Contribution to substrate specificity and transport of nonconserved residues in transmembrane domain 12 of human P-glycoprotein

Biochemistry

Volumn 37, Issue 46, 1998, Pages 16400-16409

  Hafkemeyer, Peter ^a   Dey, Saibal ^a   Ambudkar, Suresh V ^a   Hrycyna, Christine A ^a   Pastan, Ira ^a   Gottesman, Michael M ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; GENE PRODUCT; GLYCOPROTEIN P;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CANCER CELL; CONTROLLED STUDY; DRUG TRANSPORT; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION;

ADENOSINE TRIPHOSPHATE; ALANINE; AMINO ACID SEQUENCE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BINDING SITES; BIOLOGICAL TRANSPORT; CELL MEMBRANE; CONSERVED SEQUENCE; CRICETINAE; FLOW CYTOMETRY; FLUORESCENT DYES; GENES, MDR; GENETIC VECTORS; HUMANS; HYDROLYSIS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; P-GLYCOPROTEIN; PEPTIDE FRAGMENTS; PHOTOAFFINITY LABELS; PROTEIN STRUCTURE, TERTIARY; RATS; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; TRANSFECTION; TUMOR CELLS, CULTURED; VANADATES;

EID: 0032541975     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980871+     Document Type: Article

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