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Volumn 275, Issue 32, 2000, Pages 25031-25038

Conserved Walker A Ser residues in the catalytic sites of P-glycoprotein are critical for catalysis and involved primarily at the transition state step

(4) Urbatsch, I L a Gimi, K a Wilke Mounts, S a Seniors, A E a

a UNIVERSITY OF ROCHESTER MEDICAL CENTER (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN P;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CANCER CHEMOTHERAPY; CATALYSIS; CONFORMATIONAL TRANSITION; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CA(2+) MG(2+)-ATPASE; CATALYSIS; CATALYTIC DOMAIN; CLONING, MOLECULAR; CONSENSUS SEQUENCE; CONSERVED SEQUENCE; KINETICS; MAGNESIUM; MAMMALS; MUTAGENESIS, SITE-DIRECTED; P-GLYCOPROTEIN; PICHIA; POINT MUTATION; SERINE; VANADATES;

EID: 0034637483 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M003962200 Document Type: Article

Times cited : (52)

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