Drug-stimulated nucleotide trapping in the human multidrug transporter MDR1: Cooperation of the nucleotide binding domains

Journal of Biological Chemistry

Volumn 273, Issue 17, 1998, Pages 10132-10138

  Szabó, Katalin ^a   Welker, Ervin ^a   Bakos, Éva ^a   Müller, Marianna ^a   Roninson, Igor ^b   Váradi, András ^a   Sarkadi, Balázs ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE (CALCIUM MAGNESIUM); ADENOSINE TRIPHOSPHATASE INHIBITOR; CALCEIN; FLUOROURACIL; GLYCOPROTEIN P; MEMBRANE PROTEIN; N ETHYLMALEIMIDE; NUCLEOTIDE BINDING PROTEIN; RHODAMINE; VANADIC ACID; VERAPAMIL; VINCRISTINE;

ANIMAL CELL; ARTICLE; CANCER CELL; CONFORMATIONAL TRANSITION; DELETION MUTANT; DRUG BINDING SITE; DRUG HYDROLYSIS; DRUG PROTEIN BINDING; DRUG TRANSPORT; ENZYME KINETICS; ENZYME SUBSTRATE COMPLEX; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE TRANSPORT; PRIORITY JOURNAL;

ADENINE NUCLEOTIDES; ADENOSINE TRIPHOSPHATASES; BINDING SITES; CYCLOSPORINE; ENZYME INHIBITORS; ETHYLMALEIMIDE; FLUORESCEINS; FLUOROURACIL; HUMANS; P-GLYCOPROTEIN; PROTEIN BINDING; RECOMBINANT PROTEINS; VERAPAMIL;

EID: 0032562795     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.17.10132     Document Type: Article

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