Antigenic variation in trypanosomes: Enhanced phenotypic variation in a eukaryotic parasite

Advances in Parasitology

Volumn 49, Issue , 2001, Pages 1-70

  David Barry, J ^a   McCulloch, Richard ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PARASITE ANTIGEN; VARIANT SURFACE GLYCOPROTEIN;

ANTIGENIC VARIATION; GENE ACTIVATION; GENETIC RECOMBINATION; HOST PARASITE INTERACTION; HUMAN; IMMUNE RESPONSE; LIFE CYCLE; MAMMAL; NONHUMAN; PARASITE TRANSMISSION; PARASITE VIRULENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SILENT GENE; TRANSCRIPTION REGULATION; TRYPANOSOMIASIS; TSETSE FLY; ANIMAL; EVOLUTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; PARASITOLOGY; PHYSIOLOGY; TRYPANOSOMA;

EUKARYOTA; GLOSSINA (PROPER); MAMMALIA; PROTOZOA;

ANIMALS; ANTIGENIC VARIATION; EVOLUTION; HOST-PARASITE RELATIONS; HUMANS; TRYPANOSOMA; TRYPANOSOMIASIS; TSETSE FLIES; VARIANT SURFACE GLYCOPROTEINS, TRYPANOSOMA;

EID: 0035222844     PISSN: 0065308X     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0065-308x(01)49037-3     Document Type: Review

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242. A surfeit of RAD51-like genes?
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248. Genome-wide hypermutation in a subpopulation of stationary-phase cells underlies recombination-dependent adaptive mutation
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250. Assembly and functional organization of the nucleolus: Ultrastructural analysis of Saccharomyces cerevisiae mutants
251. The rate of antigenic variation in fly-transmitted and syringe-passaged infections of Trypanosoma brucei
252. Antigenic variation in Trypanosoma brucei infections: An holistic view
253. High frequency of antigenic variation in Trypanosoma brucei rhodesiense infections
254. Independent expression of the metacyclic and bloodstream variable antigen repertoires of Trypanosoma brucei rhodesiense
255. Similarity in variable antigen type composition of Trypanosoma brucei rhodesiense populations in different sites within the mouse host
256. An estimate of the size of the metacyclic variable antigen repertoire of Trypanosoma brucei rhodesiense
257. The effects of genetic exchange on variable antigen expression in Trypanosoma brucei
258. The bloodstream differentiation-division of Trypanosoma brucei studied using mitochondrial markers
259. The viral thymidine kinase gene as a tool for the study of mutagenesis in Trypanosoma brucei
260. Trypanosoma brucei sspp. development in the tsetse fly: Characterization of the postmesocyclic stages in the foregut and proboscis
261. An analysis of cosmid clones of nuclear DNA from Trypanosoma brucei shows that the genes for variant surface glycoproteins are clustered in the genome
262. Chromosomes of Kinetoplastida
263. Antigenic variation in African trypanosomes
264. Telomere interactions may condition the programming of antigen expression in Trypanosoma brucei
265. Specific binding of proteins to the noncoding strand of a crucial element of the variant surface glycoprotein, procyclin, and ribosomal promoters of Trypanosoma brucei
266. Differential RNA elongation controls the variant surface glycoprotein gene expression sites of Trypanosoma brucei
267. The telomeric GGGTAA repeats of Trypanosoma brucei contain the hypermodified base J in both strands
268. Localization of the modified base J in telomeric VSG gene expression sites of Trypanosoma brucei
269. The modified DNA base beta-D-glucosyl-hydroxymethyluracil is not found in the tsetse fly stages of Trypanosoma brucei
270. β-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres
271. Biosynthesis and function of the modified DNA base beta-D-glucosyl-hydroxymethyluracil in Trypanosoma brucei
272. Antigenic variation in syringe passaged populations of Trypanosoma (Trypanozoon) brucei. I. Rationalization of the experimental approach
273. Comparisons of variable antigenic types produced by trypanosome strains of the subgenus Trypanozoon
274. Differentiation of African trypanosomes is controlled by a density sensing mechanism which signals cell cycle arrest via the cAMP pathway
275. A major surface glycoprotein of Trypanosoma brucei is expressed transiently during development and can be regulated post-transcriptionally by glycerol or hypoxia
276. Developmental cycles and biology of pathogenic trypanosomes
277. Waves of malarial variations
278. Chromosome structure - DNA nucleotide sequence elements of a subset of the minichromosomes of the protozoan Trypanosoma brucei
279. Apoptosis in procyclic Trypanosoma brucei rhodesiense in vitro
280. Programmed cell death in trypanosomatids
281. The antigenic structure of the HIV gp 120 envelope glycoprotein
282. A VSG expression site-associated gene confers resistance to human serum in Trypanosoma rhodesiense
283. Relationship between multiple copies of a T. brucei variable surface glycoprotein gene whose expression is not controlled by duplication
284. Genetic variation of the Borrelia burgdorferi gene vlsE involves cassette-specific, segmental gene conversion
285. Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes
286. The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei
287. Alpha-amanitin-resistant transcription units in trypanosomes - A comparison of promoter sequences for a VSG gene expression site and for the ribosomal RNA genes