A surfeit of RAD51-like genes?

Trends in Genetics

Volumn 15, Issue 5, 1999, Pages 166-168

  Thacker, John ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; BIODIVERSITY; DNA REPAIR; GENETIC RECOMBINATION; GENETIC VARIABILITY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; REVIEW; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 0032913521     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-9525(99)01733-3     Document Type: Short Survey

References (30)

1. Roca A.I., Cox M.M. RecA protein: structure, function, and role in recombinational DNA repair. Prog. Nucleic Acid. Res. Mol. Biol. 56:1997;129-223.
2. Baumann P., West S.C. Role of the human RAD51 protein in homologous recombination and double-stranded-break repair. Trends Biochem. Sci. 23:1998;247-251.
3. Shinohara A.et al. Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA. Nat. Genet. 4:1993;239-243.
4. Habu T.et al. The mouse and human homologues of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon skipped transcript in meiosis. Nucleic Acids Res. 24:1996;470-477.
5. Tambini C.E.et al. The XRCC2 DNA repair gene: identification of a positional candidate. Genomics. 41:1997;84-92.
6. Liu N.et al. XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages. Mol. Cell. 1:1998;783-793.
7. Cartwright R.et al. The XRCC2 repair gene from human and mouse encodes a novel member of the recA/RAD51 family. Nucleic Acids Res. 26:1998;3084-3089.
8. Rice M.C.et al. Isolation of human and mouse genes based on homology to REC2, a recombinational repair gene from the fungus Ustilago maydis. Proc. Natl. Acad. Sci. U. S. A. 94:1997;7417-7422.
9. Albala J.S.et al. Identification of a novel human RAD51 homolog, RAD51B. Genomics. 46:1997;476-479.
10. Dosanjh M.K.et al. Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes. Nucleic Acids Res. 26:1998;1179-1184.
11. Pittman D.L.et al. Identification, characterization and genetic mapping of Rad51d, a new mouse and human RAD51/RecA-related gene. Genomics. 49:1998;103-111.
12. Cartwright R.et al. Isolation of novel human and mouse members of the recA/RAD51 recombination-repair gene family. Nucleic Acids Res. 26:1998;1653-1659.
13. Game J.C. DNA double-strand breaks and the RAD50-57 genes in Saccharomyces. Semin. Cancer Biol. 4:1993;73-83.
14. Sung P. Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase. Genes Dev. 11:1997;1111-1121.
15. Shinohara A., Ogawa T. Stimulation by Rad52 of yeast Rad51-mediated recombination. Nature. 391:1998;404-407.
16. New J.H.et al. Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A. Nature. 391:1998;407-410.
17. Clever B.et al. Recombinational repair in yeast: functional interactions between Rad51 and Rad54 proteins. EMBO J. 16:1997;2535-2544.
18. Resnick M.A. The repair of double-strand breaks in DNA: a model involving recombination. J. Theor. Biol. 59:1976;97-106.
19. Jones N.J.et al. Isolation and cross-sensitivity of X-ray sensitive mutants of V79-4 hamster cells. Mutat. Res. 183:1987;279-286.
20. Fuller L.F., Painter R.B. A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication. Mutat. Res. 193:1988;109-121.
21. Haaf T.et al. Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization to synaptonemal complexes. Proc. Natl. Acad. Sci. U. S. A. 92:1995;2298-2302.
22. Bishop D.K.et al. Xrcc3 is required for assembly of Rad51 complexes in vivo. J. Biol. Chem. 273:1998;21482-21488.
23. Havre P.A.et al. The human REC2/RAD51B gene acts as a DNA damage sensor by inducing G1 delay and hypersensitivity to ultraviolet irradiation. Cancer Res. 58:1998;4733-4739.
24. Tsuzuki T.et al. Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. Proc. Natl. Acad. Sci. U. S. A. 93:1996;6236-6240.
25. Lim D-S., Hasty P. A mutation in mouse Rad51 results in an early embryonic lethal that is suppressed by a mutation in p53. Mol. Cell. Biol. 16:1996;7133-7143.
26. Sonoda E.et al. Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death. EMBO J. 17:1998;598-608.
27. Ghabriel A.et al. okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis. Genes Dev. 12:1998;2711-2723.
28. Thacker J., Ganesh A.N. DNA break repair, radioresistance of DNA synthesis, and camptothecin sensitivity in the radiation-sensitive irs mutants: comparisons to ataxia-telangiectasia cells. Mutat. Res. 235:1990;49-58.
29. Jones N.J.et al. Biochemical and genetic analysis of chinese hamster mutants irs1 and irs2 and their comparison to cultured ataxia telangiectasia cells. Mutagenesis. 5:1990;15-23.
30. Jeanmougin F.et al. Multiple sequence alignment with Clustal X. Trends Biochem. Sci. 23:1998;403-405.