The effect of β-turn structure on the permeation of peptides across monolayers of bovine brain microvessel endothelial cells

Pharmaceutical Research

Volumn 14, Issue 10, 1997, Pages 1341-1348

  Sorensen, Mette ^a   Steenberg, Betina ^a   Knipp, Gregory T ^b   Wang, Wen ^b   Steffansen, Bente ^a   Frokjaer, Sven ^a   Borchardt, Ronald T ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF KANSAS   (United States)

Author keywords

BBMEC monolayers; Bovine brain microvessel endothelial cells; Passive diffusion; Peptide delivery; Solution conformation; Transcellular diffusion

Indexed keywords

PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DIFFUSION; DRUG STRUCTURE; DRUG TRANSPORT; ENDOTHELIUM CELL; IN VITRO STUDY; MICROVASCULATURE; NONHUMAN; PERMEABILITY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CATTLE; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; MICROCIRCULATION; OLIGOPEPTIDES; PERMEABILITY; PROTEIN STRUCTURE, SECONDARY; SOLUTIONS; STRUCTURE-ACTIVITY RELATIONSHIP; TIGHT JUNCTIONS;

EID: 0030770994     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012104301773     Document Type: Article

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