Functional clarification of MCT1-mediated transport of monocarboxylic acids at the blood-brain barrier using in vitro cultured cells and in vivo BUI studies

Pharmaceutical Research

Volumn 17, Issue 1, 2000, Pages 55-62

  Kido, Yasuto ^a,b   Tamai, Ikumi ^a,b   Okamoto, Mototsugu ^a   Suzuki, Fumio ^c   Tsuji, Akira ^a,b  

^a KANAZAWA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Benzoic acid; Blood brain barrier; Immortalized cell; MCT1; Membrane transport; Monocarboxylic acid

Indexed keywords

BENZOIC ACID; CARBOXYLIC ACID; CARRIER PROTEIN; LACTIC ACID;

ACTIVE TRANSPORT; ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; CAPILLARY ENDOTHELIUM; CELL CULTURE; CELL IMMORTALIZATION; ENDOTHELIUM CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MEMBRANE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; RAT; STEREOSPECIFICITY; TRANSPORT KINETICS;

ANIMALS; BENZOIC ACID; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN; CARRIER PROTEINS; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; HYDROGEN-ION CONCENTRATION; LACTIC ACID; MALE; MONOCARBOXYLIC ACID TRANSPORTERS; RATS; RATS, WISTAR; RNA, MESSENGER;

EID: 0034053017     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007518525161     Document Type: Article

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