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Volumn 831, Issue 1-2, 1999, Pages 229-236

Transport mechanisms for the antidepressant citalopram in brain microvessel endothelium

Author keywords

Antidepressant; Blood brain barrier; Bovine brain microvessel endothelial cell; Carrier; Enantiomer; P glycoprotein; Selective serotonin reuptake inhibitor; Stereoselectivity; Transport

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); CITALOPRAM; CYCLOSPORIN A; CYTOCHROME P450 ISOENZYME; DOPAMINE; DRUG CARRIER; GLYCOPROTEIN P; RHODAMINE 123; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; TRYPTOPHAN;

EID: 0033549263     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01461-4     Document Type: Article
Times cited : (66)

References (36)
  • 3
    • 0022640577 scopus 로고
    • Catecholamine-metabolizing enzymes of bovine brain microvessel endothelial cell monolayers
    • A. Baranczyk-Kuzma, K.L. Audus, R.T. Borchardt, Catecholamine-metabolizing enzymes of bovine brain microvessel endothelial cell monolayers, J. Neurochem. 46 (1986) 1956-1960.
    • (1986) J. Neurochem. , vol.46 , pp. 1956-1960
    • Baranczyk-Kuzma, A.1    Audus, K.L.2    Borchardt, R.T.3
  • 4
    • 0025172015 scopus 로고
    • Differential scanning calorimetry study of the interaction of antidepressant drugs, noradrenaline, and 5-hydroxytryptamine with a membrane model
    • M. Bauer, C. Megret, A. Lamure, C. Lacabanne, M.-J. Fauran-Clavel, Differential scanning calorimetry study of the interaction of antidepressant drugs, noradrenaline, and 5-hydroxytryptamine with a membrane model, J. Pharm. Sci. 79 (1990) 897-901.
    • (1990) J. Pharm. Sci. , vol.79 , pp. 897-901
    • Bauer, M.1    Megret, C.2    Lamure, A.3    Lacabanne, C.4    Fauran-Clavel, M.-J.5
  • 5
    • 0028926704 scopus 로고
    • Comparative pharmacokinetics of selective serotonin reuptake inhibitors: A look behind the mirror
    • P. Baumann, B. Rochat, Comparative pharmacokinetics of selective serotonin reuptake inhibitors: a look behind the mirror, Int. Clin. Psychopharmacol. 10 (1995) 15-21, Suppl 1.
    • (1995) Int. Clin. Psychopharmacol. , vol.10 , Issue.1 SUPPL. , pp. 15-21
    • Baumann, P.1    Rochat, B.2
  • 6
    • 0026034668 scopus 로고
    • Stereoselective efflux of (E)-10-hydroxynortriptyline enantiomers from the cerebrospinal fluid of depressed patients
    • L. Bertilsson, K. Otani, M.L. Dahl, C. Nordin, A. Aberg-Wistedt, Stereoselective efflux of (E)-10-hydroxynortriptyline enantiomers from the cerebrospinal fluid of depressed patients, Pharmacol. Toxicol. 68 (1991) 100-103.
    • (1991) Pharmacol. Toxicol. , vol.68 , pp. 100-103
    • Bertilsson, L.1    Otani, K.2    Dahl, M.L.3    Nordin, C.4    Aberg-Wistedt, A.5
  • 8
    • 0029903801 scopus 로고    scopus 로고
    • Non-response to citalopram in depressive patients: Pharmacokinetic and clinical consequences of a fluvoxamine augmentation
    • G. Bondolfi, C. Chautems, B. Rochat, G. Bertschy, P. Baumann, Non-response to citalopram in depressive patients: pharmacokinetic and clinical consequences of a fluvoxamine augmentation, Psychopharmacology 128 (1996) 421-425.
    • (1996) Psychopharmacology , vol.128 , pp. 421-425
    • Bondolfi, G.1    Chautems, C.2    Rochat, B.3    Bertschy, G.4    Baumann, P.5
  • 10
    • 0029785013 scopus 로고    scopus 로고
    • 3H]paroxetine to caudate nucleus and microvessels from porcine brain
    • 3H]paroxetine to caudate nucleus and microvessels from porcine brain, NeuroReport 7 (1996) 1405-1408.
    • (1996) NeuroReport , vol.7 , pp. 1405-1408
    • Brust, P.1    Bergmann, R.2    Johannsen, B.3
  • 11
    • 0028981588 scopus 로고
    • 3H]imipramine indicates the presence of a specific serotonin transport system on endothelial cells of porcine brain
    • 3H]imipramine indicates the presence of a specific serotonin transport system on endothelial cells of porcine brain, Neurosci. Lett. 194 (1995) 21-24.
    • (1995) Neurosci. Lett. , vol.194 , pp. 21-24
    • Brust, P.1    Bergmann, R.2    Johannsen, B.3
  • 12
    • 0030010301 scopus 로고    scopus 로고
    • Pharmacokinetic fluvoxamine-clomipramine interaction with favorable therapeutic consequences in therapy-resistant depressive patient
    • P. Conus, G. Bondolfi, C.B. Eap, F. Macciardi, P. Baumann, Pharmacokinetic fluvoxamine-clomipramine interaction with favorable therapeutic consequences in therapy-resistant depressive patient, Pharmacopsychiatry 29 (1996) 108-110.
    • (1996) Pharmacopsychiatry , vol.29 , pp. 108-110
    • Conus, P.1    Bondolfi, G.2    Eap, C.B.3    Macciardi, F.4    Baumann, P.5
  • 13
    • 0030604062 scopus 로고    scopus 로고
    • Use of rhodamine 123 to examine the functional activity of P-glycoprotein in primary cultured brain microvessel endothelial cell monolayers
    • M. Fontaine, W.F. Elmquist, D.W. Miller, Use of rhodamine 123 to examine the functional activity of P-glycoprotein in primary cultured brain microvessel endothelial cell monolayers, Life Sci. 59 (1996) 1521-1531.
    • (1996) Life Sci. , vol.59 , pp. 1521-1531
    • Fontaine, M.1    Elmquist, W.F.2    Miller, D.W.3
  • 14
    • 0027163885 scopus 로고
    • Drug concentrations in mouse brain at pharmacologically active doses of fluoxetine enantiomers
    • R.W. Fuller, H.D. Snoddy, Drug concentrations in mouse brain at pharmacologically active doses of fluoxetine enantiomers, Biochem. Pharmacol. 45 (1993) 2355-2358.
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 2355-2358
    • Fuller, R.W.1    Snoddy, H.D.2
  • 17
    • 0020416931 scopus 로고
    • Citalopram - Pharmacological profile of specific serotonin uptake inhibitor with antidepressant activity
    • J. Hyttel, Citalopram - Pharmacological profile of specific serotonin uptake inhibitor with antidepressant activity, Prog. Neuropsychopharmacol. Biol. Psychiatry 6 (1982) 277-295.
    • (1982) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.6 , pp. 277-295
    • Hyttel, J.1
  • 18
    • 0026539075 scopus 로고
    • The pharmacological effect of citalopram residues in the (S)-(+)-enantiomer
    • J. Hyttel, K.P. Bogeso, J. Perregaard, C. Sanchez, The pharmacological effect of citalopram residues in the (S)-(+)-enantiomer, J. Neural Transm. 88 (1992) 157-160.
    • (1992) J. Neural Transm. , vol.88 , pp. 157-160
    • Hyttel, J.1    Bogeso, K.P.2    Perregaard, J.3    Sanchez, C.4
  • 19
    • 0029943119 scopus 로고    scopus 로고
    • Endothelial cells of the brain and other organ systems: Some similarities and differences
    • F. Joo, Endothelial cells of the brain and other organ systems: some similarities and differences, Prog. Neurobiol. 48 (1996) 255-273.
    • (1996) Prog. Neurobiol. , vol.48 , pp. 255-273
    • Joo, F.1
  • 20
    • 0027423294 scopus 로고
    • The blood, brain barrier in vitro: The second decade
    • F. Joo, The blood, brain barrier in vitro: the second decade, Neurochem. Int. 23 (1993) 499-521.
    • (1993) Neurochem. Int. , vol.23 , pp. 499-521
    • Joo, F.1
  • 21
    • 0031893146 scopus 로고    scopus 로고
    • Organic cation transporters in intestine, kidney, liver, and brain
    • H. Koepsell, Organic cation transporters in intestine, kidney, liver, and brain, Annu. Rev. Physiol. 60 (1998) 243-260.
    • (1998) Annu. Rev. Physiol. , vol.60 , pp. 243-260
    • Koepsell, H.1
  • 22
    • 0030984995 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitor, induced serotonin syndrome: Review
    • R. Lane, D. Baldwin, Selective serotonin reuptake inhibitor, induced serotonin syndrome: review, J. Clin. Psychopharmacol. 17 (1997) 208-221.
    • (1997) J. Clin. Psychopharmacol. , vol.17 , pp. 208-221
    • Lane, R.1    Baldwin, D.2
  • 23
    • 0030053701 scopus 로고    scopus 로고
    • Transport of dopamine at the blood-brain barrier of the guinea pig: Inhibition by psychotropic drugs and nicotine
    • C.L. Martet, J.B. Mackic, J.D. Adams Jr., J.G. McComb, M.H. Weiss, B.V. Zlokovic, Transport of dopamine at the blood-brain barrier of the guinea pig: inhibition by psychotropic drugs and nicotine, Pharm. Res. 13 (1996) 290-295.
    • (1996) Pharm. Res. , vol.13 , pp. 290-295
    • Martet, C.L.1    Mackic, J.B.2    Adams J.D., Jr.3    McComb, J.G.4    Weiss, M.H.5    Zlokovic, B.V.6
  • 24
    • 23544431706 scopus 로고    scopus 로고
    • Is the probenecid-sensitive transporter in the blood-brain barrier multidrug resistance associated protein (MRP)?
    • D.W. Miller, H.Y. Han, D. Carrney, Is the probenecid-sensitive transporter in the blood-brain barrier multidrug resistance associated protein (MRP)?, Pharm. Res. 14 (1997) S332.
    • (1997) Pharm. Res. , vol.14
    • Miller, D.W.1    Han, H.Y.2    Carrney, D.3
  • 26
    • 0030727889 scopus 로고    scopus 로고
    • Citalopram - A review of its pharmacology, clinical efficacy and tolerability in the treatment of depression
    • S. Noble, P. Benfield, Citalopram - A review of its pharmacology, clinical efficacy and tolerability in the treatment of depression, CNS Drugs 8 (1997) 410-431.
    • (1997) CNS Drugs , vol.8 , pp. 410-431
    • Noble, S.1    Benfield, P.2
  • 27
    • 0030957623 scopus 로고    scopus 로고
    • Identification of three cytochrome P450 isozymes involved in N-demethylation of citalopram enantiomers in human liver microsomes
    • B. Rochat, M. Amey, M. Gillet, U.A. Meyer, P. Baumann, Identification of three cytochrome P450 isozymes involved in N-demethylation of citalopram enantiomers in human liver microsomes, Pharmacogenetics 7 (1997) 1-10.
    • (1997) Pharmacogenetics , vol.7 , pp. 1-10
    • Rochat, B.1    Amey, M.2    Gillet, M.3    Meyer, U.A.4    Baumann, P.5
  • 28
    • 0028863052 scopus 로고
    • Determination of the enantiomers of citalopram its demethylated and propionic acid metabolites in human plasma by chiral HPLC
    • B. Rochat, M. Amey, H. Van Gelderen, B. Testa, P. Baumann, Determination of the enantiomers of citalopram its demethylated and propionic acid metabolites in human plasma by chiral HPLC, Chirality 7 (1995) 389-395.
    • (1995) Chirality , vol.7 , pp. 389-395
    • Rochat, B.1    Amey, M.2    Van Gelderen, H.3    Testa, B.4    Baumann, P.5
  • 29
    • 0031751079 scopus 로고    scopus 로고
    • Stereoselective biotransformation of the selective serotonin re-uptake inhibitor citalopram and its demethylated metabolites by monoamine oxidases in human liver
    • B. Rochat, M. Kosel, G. Boss, B. Testa, M. Gillet, P. Baumann, Stereoselective biotransformation of the selective serotonin re-uptake inhibitor citalopram and its demethylated metabolites by monoamine oxidases in human liver, Biochem. Pharmacol. 56 (1998) 15-23.
    • (1998) Biochem. Pharmacol. , vol.56 , pp. 15-23
    • Rochat, B.1    Kosel, M.2    Boss, G.3    Testa, B.4    Gillet, M.5    Baumann, P.6
  • 30
    • 0345030443 scopus 로고    scopus 로고
    • Membrane transporters: Gateways to the future
    • W. Sadee, Membrane transporters: gateways to the future, Pharm. News 4 (1997) 8-11.
    • (1997) Pharm. News , vol.4 , pp. 8-11
    • Sadee, W.1
  • 31
    • 0031870979 scopus 로고    scopus 로고
    • The absence of stereoselective P-glycoprotein-mediated transport of R/S-verapamil across the rat jejunum
    • R. Sandstrom, A. Karlsson, H. Lennernas, The absence of stereoselective P-glycoprotein-mediated transport of R/S-verapamil across the rat jejunum, J. Pharm. Pharmacol. 50 (1998) 729-735.
    • (1998) J. Pharm. Pharmacol. , vol.50 , pp. 729-735
    • Sandstrom, R.1    Karlsson, A.2    Lennernas, H.3
  • 32
    • 0024437542 scopus 로고
    • Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by bovine brain microvessel endothelial cells
    • G.K. Scriba, R.T. Borchardt, Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by bovine brain microvessel endothelial cells, Brain Res. 501 (1989) 175-178.
    • (1989) Brain Res. , vol.501 , pp. 175-178
    • Scriba, G.K.1    Borchardt, R.T.2
  • 33
    • 0032518454 scopus 로고    scopus 로고
    • A general pattern for substrate recognition by P-glycoprotein
    • A. Seelig, A general pattern for substrate recognition by P-glycoprotein, Eur. J. Biochem. 251 (1998) 252-261.
    • (1998) Eur. J. Biochem. , vol.251 , pp. 252-261
    • Seelig, A.1
  • 34
    • 0030682236 scopus 로고    scopus 로고
    • Steady-state pharmacokinetics of the enantiomers of citalopram and its metabolites in humans
    • J. Sidhu, M. Priskorn, M. Poulsen, A. Segonzac, G. Grollier, F. Larsen, Steady-state pharmacokinetics of the enantiomers of citalopram and its metabolites in humans, Chirality 9 (1997) 686-692.
    • (1997) Chirality , vol.9 , pp. 686-692
    • Sidhu, J.1    Priskorn, M.2    Poulsen, M.3    Segonzac, A.4    Grollier, G.5    Larsen, F.6
  • 35
    • 0031746091 scopus 로고    scopus 로고
    • Distinct effects of imipramine on 5-hydroxytryptamine uptake mediated by the recombinant rat serotonin transporter SERT1
    • C. Sur, H. Betz, P. Schloss, Distinct effects of imipramine on 5-hydroxytryptamine uptake mediated by the recombinant rat serotonin transporter SERT1, J. Neurochem. 70 (1998) 2545-2553.
    • (1998) J. Neurochem. , vol.70 , pp. 2545-2553
    • Sur, C.1    Betz, H.2    Schloss, P.3


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