Characterization of transferrin receptor in an immortalized cell line of rat brain endothelial cells, RBE4

Journal of Receptor and Signal Transduction Research

Volumn 19, Issue 1-4, 1999, Pages 729-739

  Huwyler, J ^a   Froidevaux, S ^a   Roux, F ^b   Eberle, A N ^a  

^a UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^b HÔPITAL FERNAND WIDAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

RECEPTOR ANTIBODY; TRANSFERRIN RECEPTOR;

ACCURACY; ANIMAL CELL; ANTIGEN BINDING; CELL MEMBRANE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOSOL; DISSOCIATION CONSTANT; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; RAT; RECEPTOR BINDING;

ANIMALIA; MURINAE;

EID: 0033037525     PISSN: 10799893     EISSN: None     Source Type: Journal    
DOI: 10.3109/10799899909036683     Document Type: Conference Paper

References (20)

1. Pardridge, W.M. Vector-mediated peptide drug delivery to the brain. Adv. Drug Delivery Rev. 15, 109-146, 1995.
2. Shah, D.; and Shen, W.C. Transcellular delivery of an insulin-transferrin conjugate in enterocyte-like Caco-2 cells. J. Pharm. Sci. 85, 1306-1311, 1996.
3. Aisen, P.; and Litowsky, I. Iron transport and storage. Annu. Rev. Biochem. 49, 357-393, 1980.
4. 125I]transferrin through the rat blood-brain barrier. Brain Res. 683, 164-171, 1995.
5. Jefferies, W.A.; Brandon, M.R.; Hunt, S.V.; Williams, A.F.; Gatter, K.C.; and Mason, D.Y. Transferrin receptor on endothelium of brain capillaries. Nature 312, 162-163, 1984.
6. Friden, P.M.; Walus, L.R.; Musso, G.F.; Taylor, M.A.; Malfroy, B.; and Starzyk, R.M. Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier. Proc. Natl. Acad. Sci. USA 88, 4771-4775, 1991.
7. Pardridge, W.M.; Buciak, J.L.; and Friden, P.M. Selective transport of an anti-transferrin receptor antibody through the blood-brain barrier. J. Pharmacol. Exp. Ther. 259, 66-70, 1991.
8. Pardridge, W.M.; Boado, R.J.; and Kang, Y.S. Vector-mediated delivery of a polyamide ("peptide") nucleic acid analogue through the blood-brain barrier in vivo. Proc. Natl. Acad. Sci. USA 92, 5592-5596, 1995.
9. Huwyler, J.; Wu, D.; and Pardridge, W.M. Brain drug delivery of small molecules using immunoliposomes. Proc. Natl. Acad. Sci. USA 93, 14164-14169, 1996.
10. Huwyler, J.; and Pardridge, W.M. Examination of blood-brain barrier transferrin receptor by confocal fluorescent microscopy of unfixed isolated rat brain capillaries. J. Neurochem. 70, 883-886, 1998.
11. Descamps, L.; Dehouck, M.-P.; Torpier, G.; and Cecchelli, R. Receptor-mediated transcytosis of transferrin through blood-brain barrier endothelial cells. Am. J. Physiol. 270, H1149-H1158, 1996.
12. Durieu Trautmann, O.; Federici, C.; Creminon, C.; Foignant Chaverot, N.; Roux, F.; Claire, M.; Strosberg, A.D.; and Couraud, P.O. Nitric oxide and endothelin secretion by brain microvessel endothelial cells: regulation by cyclic nucleotides. J. Cell. Physiol. 155, 104-111, 1993.
13. Roux, F.; Durieu Trautmann, O.; Chaverot, N.; Claire, M.; Mailly, P.; Bourre, J.M.; Strosberg, A.D.; and Couraud, P.O. Regulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells. J. Cell. Physiol. 159, 101-113, 1994.
14. Jefferies, W.A.; Brandon, M.R.; Williams, A.F.; and Hunt, S.V. Analysis of lymphopoietic stem cells with a monoclonal antibody to the rat transferrin receptor. Immunology 54, 333-341, 1985.
15. Begley, D.J.; Lechardeur, D.; Chen, Z.D.; Rollinson, C.; Bardoul, M.; Roux, F.; Scherman, D.; and Abbott, N.J. Functional expression of P-glycoprotein in an immortalised cell line of rat brain endothelial cells, RBE4. J. Neurochem. 67, 988-995, 1996.
16. Lee, P.H.; Nguyen, T.M.; Chung, N.N.; Schiller, P.W; and Chang, K.J. Tyrosine-iodination converts the delta-opioid peptide antagonist TIPP to an agonist. Eur. J. Pharmacol. 280, 211-214, 1995.
17. Seelig, A.; Gottschlich, R.; and Devant, R.M. A method to determine the ability of drugs to diffuse through the blood-brain barrier. Proc. Natl. Acad. Sci. USA 91, 68-72, 1994.
18. Rudolf, J.R.; Regoeczi, E.; and Southward, S. Quantification of rat hepatocyte transferrin receptors with poly- and monoclonal antibodies and protein A. Histochem. 88, 187-192, 1988.
19. Raub, T.J.; and Newton, C.R. Recycling kinetics and transcytosis of transferrin in primary cultures of bovine brain microvessel endothelial cells. J. Cellular Physiol. 149, 1991.
20. van Gelder, W.; Huijskes-Heins, M.I.E.; van Dijk, J.P.; Cleton-Soeteman, M.I.; and van Eijk, H.G. Quantification of different transferrin receptor pools in primary cultures of porcine blood-brain barrier endothelial cells. J. Neurochem. 64, 2708-2715, 1995.