-
1
-
-
0023022986
-
Characterization of an in vitro blood-brain barrier model system for studying drug transport and metabolism
-
Audus, K. L.; Borchardt, R. T. Characterization of an in vitro blood-brain barrier model system for studying drug transport and metabolism. Pharm. Res. 1986, 3, 81-87.
-
(1986)
Pharm. Res.
, vol.3
, pp. 81-87
-
-
Audus, K.L.1
Borchardt, R.T.2
-
2
-
-
0000953843
-
Application of cultured endothelial cells of the brain microvasculature in the study of the blood-brain barrier
-
Miller, D. W.; Audus, K. L.; Borchardt, R. T. Application of cultured endothelial cells of the brain microvasculature in the study of the blood-brain barrier. J. Tissue Cult. Methods 1992, 14, 217-224.
-
(1992)
J. Tissue Cult. Methods
, vol.14
, pp. 217-224
-
-
Miller, D.W.1
Audus, K.L.2
Borchardt, R.T.3
-
3
-
-
0024267858
-
Characterization of an "in vitro" blood-brain barrier: Effects of molecular size and lipophilicity on cerebrovascular endothelial transport of drugs
-
van Bree, J. B. M. M.; de Boer, A. G.; Danhof, M.; Ginsel, L. A.; Breimer, D. D. Characterization of an "in vitro" blood-brain barrier: Effects of molecular size and lipophilicity on cerebrovascular endothelial transport of drugs. J. Pharmacol. Exp. Ther. 1988, 247, 1233-1239.
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.247
, pp. 1233-1239
-
-
Van Bree, J.B.M.M.1
De Boer, A.G.2
Danhof, M.3
Ginsel, L.A.4
Breimer, D.D.5
-
4
-
-
0025329190
-
Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier
-
Pardridge, W. M.; Triguero, D.; Yang, J.; Cancilla, P. A. Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier. J. Pharmacol. Exp. Ther. 1990, 253, 884-891.
-
(1990)
J. Pharmacol. Exp. Ther.
, vol.253
, pp. 884-891
-
-
Pardridge, W.M.1
Triguero, D.2
Yang, J.3
Cancilla, P.A.4
-
5
-
-
0024325094
-
The application of bovine brain microvessel endothelial-cell monolayers grown onto polycarbonate membranes in vitro to estimate the potential permeability of solutes through the blood-brain barrier
-
Shah, M. V.; Audus, K. L.; Borchardt, R. T. The application of bovine brain microvessel endothelial-cell monolayers grown onto polycarbonate membranes in vitro to estimate the potential permeability of solutes through the blood-brain barrier. Pharm. Res. 1989, 6, 624-627.
-
(1989)
Pharm. Res.
, vol.6
, pp. 624-627
-
-
Shah, M.V.1
Audus, K.L.2
Borchardt, R.T.3
-
6
-
-
0000352082
-
Pharmacology of the blood-brain barrier
-
Neuwelt, E. A., Ed.; Plenum: New York
-
Fenstermacher, J. D. Pharmacology of the Blood-Brain Barrier. In Implications of the Blood-Brain Barrier and Its Manipulation; Neuwelt, E. A., Ed.; Plenum: New York, 1989; Vol. 1, pp 137-155.
-
(1989)
Implications of the Blood-brain Barrier and Its Manipulation
, vol.1
, pp. 137-155
-
-
Fenstermacher, J.D.1
-
7
-
-
0021840830
-
Cross-linked collagen surface for cell culture that is stable, uniform, and optically superior to conventional surfaces
-
Macklis, J. D.; Sidman, R. L.; Shine, H. D. Cross-linked collagen surface for cell culture that is stable, uniform, and optically superior to conventional surfaces. In Vitro Cell. Dev. Biol. 1985, 21, 189-194.
-
(1985)
In Vitro Cell. Dev. Biol.
, vol.21
, pp. 189-194
-
-
Macklis, J.D.1
Sidman, R.L.2
Shine, H.D.3
-
8
-
-
71849104860
-
Protein measurement with the folin phenol reagent
-
Lowry, O. H.; Rosebrough, N. J.; Farr, A. L.; Randall, R. J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 1951, 193, 265-275.
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
9
-
-
0026293045
-
Blood-brain barrier: Transport studies in isolated brain capillaries and in cultured brain endothelial cells
-
Academic Press: New York
-
Takakura, Y.; Audus, K. L.; Borchardt, R. T. Blood-brain barrier: Transport studies in isolated brain capillaries and in cultured brain endothelial cells. In Advances in Pharmacology; Academic Press: New York, 1991; Vol. 22, pp 137-165.
-
(1991)
Advances in Pharmacology
, vol.22
, pp. 137-165
-
-
Takakura, Y.1
Audus, K.L.2
Borchardt, R.T.3
-
10
-
-
0025102678
-
The use of cultured epithelial and endothelial cells for drug transport and metabolism studies
-
Audus, K. L.; Bartel, R. L.; Hidalgo, I. J.; Borchardt, R. T. The use of cultured epithelial and endothelial cells for drug transport and metabolism studies. Pharm. Res. 1990, 7, 435-451.
-
(1990)
Pharm. Res.
, vol.7
, pp. 435-451
-
-
Audus, K.L.1
Bartel, R.L.2
Hidalgo, I.J.3
Borchardt, R.T.4
-
11
-
-
0027423294
-
The blood-brain barrier in vitro: The second decade
-
Joo, F. The blood-brain barrier in vitro: The second decade. Neurochem. Int. 1993, 23, 499-521.
-
(1993)
Neurochem. Int.
, vol.23
, pp. 499-521
-
-
Joo, F.1
-
12
-
-
0026502638
-
The cerebral microvessels in culture, an update
-
Joo, F. The cerebral microvessels in culture, an update. J. Neurochem. 1992, 58, 1-17.
-
(1992)
J. Neurochem.
, vol.58
, pp. 1-17
-
-
Joo, F.1
-
13
-
-
0019821977
-
Primary culture of capillary endothelium from rat brain
-
Bowman, P. D.; Betz, A. L.; Ar, D.; Wolinsky, J. S.; Penney, J. B.; Shivers, R. R.; Goldstein, G. W. Primary culture of capillary endothelium from rat brain. In Vitro 1981, 17, 353-362.
-
(1981)
In Vitro
, vol.17
, pp. 353-362
-
-
Bowman, P.D.1
Betz, A.L.2
Ar, D.3
Wolinsky, J.S.4
Penney, J.B.5
Shivers, R.R.6
Goldstein, G.W.7
-
14
-
-
0018938093
-
Isolation and characterization of brain endothelial cells: Morphology and enzyme activity
-
Williams, S. T.; Gillis, J. F.; Matthews, M. A.; Wagner, R. C.; Bitensky, M. W. Isolation and characterization of brain endothelial cells: morphology and enzyme activity. J. Neurochem. 1980, 32, 374-381.
-
(1980)
J. Neurochem.
, vol.32
, pp. 374-381
-
-
Williams, S.T.1
Gillis, J.F.2
Matthews, M.A.3
Wagner, R.C.4
Bitensky, M.W.5
-
15
-
-
0030457859
-
Localization of purine metabolizing enzymes in bovine brain microvessel endothelial cells: An enzymatic blood-brain barrier for dideoxynucleosides?
-
Johnson, M. D.; Anderson, B. D. Localization of purine metabolizing enzymes in bovine brain microvessel endothelial cells: an enzymatic blood-brain barrier for dideoxynucleosides? Pharm. Res. 1996, 13, 1881-1886.
-
(1996)
Pharm. Res.
, vol.13
, pp. 1881-1886
-
-
Johnson, M.D.1
Anderson, B.D.2
-
16
-
-
0021020420
-
Brain metabolism: A perspective from the blood-brain barrier
-
Pardridge, W. M. Brain metabolism: A perspective from the blood-brain barrier. Physiol. Rev. 1983, 63, 1481-1535.
-
(1983)
Physiol. Rev.
, vol.63
, pp. 1481-1535
-
-
Pardridge, W.M.1
-
17
-
-
0031031742
-
In vitro models to predict blood-brain barrier permeability
-
Eddy, E. P.; Maleef, B. E.; Hart, T. K.; Smith, P. L. In vitro models to predict blood-brain barrier permeability. Adv. Drug Delivery Rev. 1997, 23, 185-198.
-
(1997)
Adv. Drug Delivery Rev.
, vol.23
, pp. 185-198
-
-
Eddy, E.P.1
Maleef, B.E.2
Hart, T.K.3
Smith, P.L.4
-
18
-
-
0001165874
-
Blood-brain barrier
-
Renkin, E. M., Michel, C. C., Eds.; American Physiological Society: Washington, DC
-
Fenstermacher, J. D.; Rapoport, S. I. Blood-brain barrier. In Handbook of Physiology. Section 2: The Cardiovascular System. Vol IV: Microcirculation.; Renkin, E. M., Michel, C. C., Eds.; American Physiological Society: Washington, DC, 1984; Vol. IV, pp 969-1000.
-
(1984)
Handbook of Physiology. Section 2: The Cardiovascular System. Vol IV: Microcirculation
, vol.4
, pp. 969-1000
-
-
Fenstermacher, J.D.1
Rapoport, S.I.2
-
19
-
-
0018398457
-
Drug entry into the brain
-
Rapoport, S. I.; Ohno, K.; Pettigrew, K. D. Drug entry into the brain. Brain Res. 1979, 172, 354-359.
-
(1979)
Brain Res.
, vol.172
, pp. 354-359
-
-
Rapoport, S.I.1
Ohno, K.2
Pettigrew, K.D.3
-
20
-
-
0028299612
-
In vitro and in vivo transport of zidovudine (AZT) across the blood-brain barrier and the effect of transport inhibitors
-
Masereeuw, R.; Jaehde, U.; Langemeijer, M. W. E.; de Boer, A. G.; Breimer, D. D. In vitro and in vivo transport of zidovudine (AZT) across the blood-brain barrier and the effect of transport inhibitors. Pharm. Res. 1994, 11, 324-330.
-
(1994)
Pharm. Res.
, vol.11
, pp. 324-330
-
-
Masereeuw, R.1
Jaehde, U.2
Langemeijer, M.W.E.3
De Boer, A.G.4
Breimer, D.D.5
-
21
-
-
0025140975
-
Brain and cerebrospinal fluid uptake of zidovudine (AZT) in rats after intravenous injection
-
Galinsky, R. E.; Hoesterey, B. L.; Anderson, B. D. Brain and cerebrospinal fluid uptake of zidovudine (AZT) in rats after intravenous injection. Life Sci. 1990, 47, 781-788.
-
(1990)
Life Sci.
, vol.47
, pp. 781-788
-
-
Galinsky, R.E.1
Hoesterey, B.L.2
Anderson, B.D.3
-
22
-
-
0023898828
-
Pyrimidine dideoxyribonucleosides: Selectivity of penetration into cerebrospinal fluid
-
Collins, J. M.; Klecker, R. W., Jr.; Kelley, J. A.; Roth, J. S.; McCully, C. L.; Balis, F. M.; Poplack, D. G. Pyrimidine dideoxyribonucleosides: Selectivity of penetration into cerebrospinal fluid. J. Pharmacol. Exp. Ther. 1988, 245, 466-470.
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.245
, pp. 466-470
-
-
Collins, J.M.1
Klecker R.W., Jr.2
Kelley, J.A.3
Roth, J.S.4
McCully, C.L.5
Balis, F.M.6
Poplack, D.G.7
-
23
-
-
0024991044
-
Modeling the enhanced uptake of zidovudine (AZT) into the cerebrospinal fluid. 1. Effect of probenecid
-
Sawchuk, R. J.; Heydaya, M. A. Modeling the enhanced uptake of zidovudine (AZT) into the cerebrospinal fluid. 1. Effect of probenecid. Pharm. Res. 1990, 7, 332-338.
-
(1990)
Pharm. Res.
, vol.7
, pp. 332-338
-
-
Sawchuk, R.J.1
Heydaya, M.A.2
-
24
-
-
0031946993
-
In vitro blood-brain barrier permeability of nevirapine compared to other HIV antiretroviral agents
-
Glynn, S. L.; Yazdanian, M. In vitro blood-brain barrier permeability of nevirapine compared to other HIV antiretroviral agents. J. Pharm. Sci. 1998, 87, 306-310.
-
(1998)
J. Pharm. Sci.
, vol.87
, pp. 306-310
-
-
Glynn, S.L.1
Yazdanian, M.2
-
25
-
-
0026719204
-
Drug transfer across the blood-brain barrier: Correlation between in vitro and in vivo models
-
Dehouck, M. P.; Jolliet-Riant, P.; Bree, F.; Fruchart, J. C.; Cecchelli, R.; Tillement, J. P. Drug transfer across the blood-brain barrier: correlation between in vitro and in vivo models. J. Neurochem. 1992, 58, 1790-1797.
-
(1992)
J. Neurochem.
, vol.58
, pp. 1790-1797
-
-
Dehouck, M.P.1
Jolliet-Riant, P.2
Bree, F.3
Fruchart, J.C.4
Cecchelli, R.5
Tillement, J.P.6
-
26
-
-
0025265046
-
An easier, reproducible, and mass-production method to study the blood-brain barrier in vitro
-
Dehouck, M.-P.; Meresse, S.; Delorme, P.; Fruchart, J.-C.; Cecchelli, R. An easier, reproducible, and mass-production method to study the blood-brain barrier in vitro. J. Neurochem. 1990, 54, 1798-1801.
-
(1990)
J. Neurochem.
, vol.54
, pp. 1798-1801
-
-
Dehouck, M.-P.1
Meresse, S.2
Delorme, P.3
Fruchart, J.-C.4
Cecchelli, R.5
-
27
-
-
0029775029
-
Signal transduction and glial cell modulation of cultured brain microvessel endothelial cell tight junctions
-
Raub, T. J. Signal transduction and glial cell modulation of cultured brain microvessel endothelial cell tight junctions. Am. J. Physiol. 1996, 271, C495-C503.
-
(1996)
Am. J. Physiol.
, vol.271
-
-
Raub, T.J.1
-
28
-
-
0026322983
-
A cell culture model of the blood-brain barrier
-
Rubin, L. L.; Hall, D. E.; Porter, S.; Barbu, K.; Cannon, C.; Horner, H. C.; Janatpour, M.; Liaw, C. W.; Manning, K.; Morales, J.; Tanner, L. I.; Tomaselli, K. J.; Bard, F. A cell culture model of the blood-brain barrier. J. Cell Biol. 1991, 115, 1725-1735.
-
(1991)
J. Cell Biol.
, vol.115
, pp. 1725-1735
-
-
Rubin, L.L.1
Hall, D.E.2
Porter, S.3
Barbu, K.4
Cannon, C.5
Horner, H.C.6
Janatpour, M.7
Liaw, C.W.8
Manning, K.9
Morales, J.10
Tanner, L.I.11
Tomaselli, K.J.12
Bard, F.13
-
29
-
-
0027163839
-
Drug transfer across the blood-brain barrier: Comparison of in vitro and in vivo models
-
Drewes, L. R., Betz, A. L., Eds.; Plenum Press: New York
-
Chesne, C.; Dehouck, M. P.; Jolliet-Riant, P.; Bree, F.; Tillement, J. P.; Dehouck, B.; Fruchart, J. C.; Cecchelli, R. Drug transfer across the blood-brain barrier: comparison of in vitro and in vivo models. In Frontiers in Cerebral Vascular Biology: Transport and Its Regulation; Drewes, L. R., Betz, A. L., Eds.; Plenum Press: New York, 1993; pp 113-115.
-
(1993)
Frontiers in Cerebral Vascular Biology: Transport and Its Regulation
, pp. 113-115
-
-
Chesne, C.1
Dehouck, M.P.2
Jolliet-Riant, P.3
Bree, F.4
Tillement, J.P.5
Dehouck, B.6
Fruchart, J.C.7
Cecchelli, R.8
-
30
-
-
0000545811
-
An in situ brain perfusion technique to study cerebrovascular transport in the rat
-
Takasato, Y.; Rapoport, S. L.; Smith, Q. R. An in situ brain perfusion technique to study cerebrovascular transport in the rat. Am. J. Physiol. 1984, 247, H484-H493.
-
(1984)
Am. J. Physiol.
, vol.247
-
-
Takasato, Y.1
Rapoport, S.L.2
Smith, Q.R.3
-
31
-
-
0030954863
-
Distributed model analysis of 3′-azido-3′-deoxythymidine and 2′,3′-dideoxyinosine distribution in brain tissue and cerebrospinal fluid
-
Takasawa, K.; Terasaki, T.; Suzuki, H.; Oooie, T.; Sugiyama, Y. Distributed model analysis of 3′-azido-3′-deoxythymidine and 2′,3′-dideoxyinosine distribution in brain tissue and cerebrospinal fluid. J. Pharmacol. Exp. Ther. 1997, 282, 1509-1517.
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.282
, pp. 1509-1517
-
-
Takasawa, K.1
Terasaki, T.2
Suzuki, H.3
Oooie, T.4
Sugiyama, Y.5
-
32
-
-
0019124032
-
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability
-
Levin, V. A. Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability. J. Med. Chem. 1980, 23, 682-684.
-
(1980)
J. Med. Chem.
, vol.23
, pp. 682-684
-
-
Levin, V.A.1
-
33
-
-
0023235207
-
Effect of penetration enhancers on the permeation of mannitol, hydrocortisone and progesterone through human skin
-
Barry, B. W.; Bennett, S. L. Effect of penetration enhancers on the permeation of mannitol, hydrocortisone and progesterone through human skin. J. Pharm. Pharmacol. 1987, 39, 535-546
-
(1987)
J. Pharm. Pharmacol.
, vol.39
, pp. 535-546
-
-
Barry, B.W.1
Bennett, S.L.2
-
34
-
-
0018097665
-
Diffusion within egg lecithin bilayers resembles that within soft polymers
-
Wolosin, J. M.; Ginsburg, H.; Lieb, W. R.; Stein, W. D. Diffusion within egg lecithin bilayers resembles that within soft polymers. J. Gen. Physiol. 1978, 71, 93-100.
-
(1978)
J. Gen. Physiol.
, vol.71
, pp. 93-100
-
-
Wolosin, J.M.1
Ginsburg, H.2
Lieb, W.R.3
Stein, W.D.4
-
35
-
-
0025826715
-
Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs
-
Barchi, J. J., Jr.; Marquez, V. E.; Driscoll, J. S.; Ford, H., Jr.; Mitsuya, H.; Shirasaka, T.; Aoki, S.; Kelley, J. A. Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs. J. Med. Chem. 1991, 34, 1647-1655.
-
(1991)
J. Med. Chem.
, vol.34
, pp. 1647-1655
-
-
Barchi J.J., Jr.1
Marquez, V.E.2
Driscoll, J.S.3
Ford H., Jr.4
Mitsuya, H.5
Shirasaka, T.6
Aoki, S.7
Kelley, J.A.8
|