-
1
-
-
0026323665
-
Purification of the inducible murine macrophage nitric oxide synthase: Identification as a flavoprotein
-
Hevel, J. M., K. A. White, and M. A. Marletta. 1991. Purification of the inducible murine macrophage nitric oxide synthase: identification as a flavoprotein, J. Biol. Chem. 266:22789.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 22789
-
-
Hevel, J.M.1
White, K.A.2
Marletta, M.A.3
-
2
-
-
0026729267
-
Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme
-
Lowenstein, C. J., C. S. Glatt, D. S. Bredt, and S. H. Snyder. 1992. Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme. Proc. Natl. Acad. Sci. USA 89:6711.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 6711
-
-
Lowenstein, C.J.1
Glatt, C.S.2
Bredt, D.S.3
Snyder, S.H.4
-
3
-
-
0026569273
-
Cloning and characterization of inducible nitric oxide synthase from mouse macrophages
-
Xie, Q.-W., H. J. Cho, J. Calaycay, R. A. Mumford, K. M. Swiderek, T. D. Lee, A. Ding, T. Troso, and C. Nathan. 1992. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 256:225.
-
(1992)
Science
, vol.256
, pp. 225
-
-
Xie, Q.-W.1
Cho, H.J.2
Calaycay, J.3
Mumford, R.A.4
Swiderek, K.M.5
Lee, T.D.6
Ding, A.7
Troso, T.8
Nathan, C.9
-
4
-
-
0028999596
-
Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase
-
MacMicking, J. D., C. Nathan, G. Hom, N. Chartrain, D. S. Fletcher, M. Trumbauer, K. Stevens, Q.-W. Xie, K. Sokol, N. Hutchinson, H. Chen, and J. S. Mudgett. 1995. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 81:641.
-
(1995)
Cell
, vol.81
, pp. 641
-
-
Macmicking, J.D.1
Nathan, C.2
Hom, G.3
Chartrain, N.4
Fletcher, D.S.5
Trumbauer, M.6
Stevens, K.7
Xie, Q.-W.8
Sokol, K.9
Hutchinson, N.10
Chen, H.11
Mudgett, J.S.12
-
5
-
-
0025609915
-
Tumor necrosis factor-α synergizes with IFN-γ in mediating killing of Leishmania major through the induction of nitric-oxide
-
Liew, F. Y., Y. Li, and S. Millott. 1990. Tumor necrosis factor-α synergizes with IFN-γ in mediating killing of Leishmania major through the induction of nitric-oxide. J. Immunol. 145:4306.
-
(1990)
J. Immunol.
, vol.145
, pp. 4306
-
-
Liew, F.Y.1
Li, Y.2
Millott, S.3
-
6
-
-
0025648446
-
Leishmania major amastigotes initiate the L-arginine-dependent killing mechanism in IFN-γ-stimulated macrophages by induction of TNF-α
-
Green, S. J., R. M. Crawford, J. T. Hockmeyer, M. S. Meltzer, and C. A. Nacy. 1990. Leishmania major amastigotes initiate the L-arginine-dependent killing mechanism in IFN-γ-stimulated macrophages by induction of TNF-α. J. Immunol. 145:4290.
-
(1990)
J. Immunol.
, vol.145
, pp. 4290
-
-
Green, S.J.1
Crawford, R.M.2
Hockmeyer, J.T.3
Meltzer, M.S.4
Nacy, C.A.5
-
7
-
-
0026549480
-
Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages
-
Chan, J., Y. Xing, R. S. Magliozzo, and B. R. Bloom. 1992. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J. Exp. Med. 175:1111.
-
(1992)
J. Exp. Med.
, vol.175
, pp. 1111
-
-
Chan, J.1
Xing, Y.2
Magliozzo, R.S.3
Bloom, B.R.4
-
8
-
-
0027488067
-
Inhibition of viral replication by interferon-γ-induced nitric oxide synthase
-
Karupiah, G., Q.-w. Xie, R. M. L. Buller, C. Nathan, C. Duarte, and J. D. MacMicking. 1993. Inhibition of viral replication by interferon-γ-induced nitric oxide synthase. Science 261:1445.
-
(1993)
Science
, vol.261
, pp. 1445
-
-
Karupiah, G.1
Xie, Q.-W.2
Buller, R.M.L.3
Nathan, C.4
Duarte, C.5
MacMicking, J.D.6
-
9
-
-
0027459588
-
Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing
-
Lorsbach, R. B., W. J. Murphy, C. J. Lowenstein, S. H. Snyder, and S. W. Russell. 1993. Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. J. Biol. Chem. 268:1908.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 1908
-
-
Lorsbach, R.B.1
Murphy, W.J.2
Lowenstein, C.J.3
Snyder, S.H.4
Russell, S.W.5
-
10
-
-
0031010661
-
Identification of nitric oxide synthase as a protective locus against tuberculosis
-
MacMicking, J. D., R. J. North, R. LaCourse, J. S. Mudgett, S. K. Shah, and C. F. Nathan. 1997. Identification of nitric oxide synthase as a protective locus against tuberculosis. Proc. Natl. Acad. Sci. USA 94:5243.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5243
-
-
MacMicking, J.D.1
North, R.J.2
LaCourse, R.3
Mudgett, J.S.4
Shah, S.K.5
Nathan, C.F.6
-
11
-
-
0028270719
-
Regulation of biosynthesis of nitric oxide
-
Nathan, C., and Q. W. Xie. 1994. Regulation of biosynthesis of nitric oxide. J. Biol. Chem. 269:13725.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 13725
-
-
Nathan, C.1
Xie, Q.W.2
-
12
-
-
0023408236
-
Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: Precursors and role of the respiratory burst
-
Iyengar, R., D. J. Stuehr, and M. A. Marletta. 1987. Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst. Proc. Natl. Acad. Sci. USA 84:6369.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 6369
-
-
Iyengar, R.1
Stuehr, D.J.2
Marletta, M.A.3
-
13
-
-
0023706894
-
Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages: Comparison of activating cytokines and evidence for independent production
-
Ding, A. H., C. F. Nathan, and D. J. Stuehr. 1988. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages: comparison of activating cytokines and evidence for independent production. J. Immunol. 141:2407.
-
(1988)
J. Immunol.
, vol.141
, pp. 2407
-
-
Ding, A.H.1
Nathan, C.F.2
Stuehr, D.J.3
-
14
-
-
0023796162
-
Interferon-γ and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages
-
Drapier, J. C., J. Wietzerbin, and J. B. J. Hibbs. 1988. Interferon-γ and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages. Eur. J. Immunol. 18:1587.
-
(1988)
Eur. J. Immunol.
, vol.18
, pp. 1587
-
-
Drapier, J.C.1
Wietzerbin, J.2
Hibbs, J.B.J.3
-
15
-
-
0028061860
-
Synergistic cooperation between phorbol ester and IFN-γ for induction of nitric oxide synthesis in murine peritoneal macrophages
-
Jun, C. D., B. M. Choi, H. Ryu, J. Y. Um, H. J. Kwak, B. S. Lee, S. G. Paik, H. M. Kim, and H. T. Chung. 1994. Synergistic cooperation between phorbol ester and IFN-γ for induction of nitric oxide synthesis in murine peritoneal macrophages. J. Immunol. 153:3684.
-
(1994)
J. Immunol.
, vol.153
, pp. 3684
-
-
Jun, C.D.1
Choi, B.M.2
Ryu, H.3
Um, J.Y.4
Kwak, H.J.5
Lee, B.S.6
Paik, S.G.7
Kim, H.M.8
Chung, H.T.9
-
16
-
-
0028243464
-
Regulation of nitric-oxide synthase mRNA expression by interferon-γ and picolinic acid
-
Melillo, G., G. W. Cox, A. Biragyn, L. A. Sheffler, and L. Varesio. 1994. Regulation of nitric-oxide synthase mRNA expression by interferon-γ and picolinic acid. J. Biol. Chem. 269:8128.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 8128
-
-
Melillo, G.1
Cox, G.W.2
Biragyn, A.3
Sheffler, L.A.4
Varesio, L.5
-
17
-
-
0028786601
-
A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
-
Melillo, G., T. Musso, A. Sica, L. S. Taylor, G. W. Cox, and L. Varesio. 1995. A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J. Exp. Med. 182:1683.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1683
-
-
Melillo, G.1
Musso, T.2
Sica, A.3
Taylor, L.S.4
Cox, G.W.5
Varesio, L.6
-
18
-
-
0030587161
-
Regulation of inducible nitric oxide synthase expression in IFN-γ-treated murine macrophages cultured under hypoxic conditions
-
Melillo, G., L. S. Taylor, A. Brooks, G. W. Cox, and L. Varesio. 1996. Regulation of inducible nitric oxide synthase expression in IFN-γ-treated murine macrophages cultured under hypoxic conditions. J. Immunol. 157:2638.
-
(1996)
J. Immunol.
, vol.157
, pp. 2638
-
-
Melillo, G.1
Taylor, L.S.2
Brooks, A.3
Cox, G.W.4
Varesio, L.5
-
19
-
-
0027255749
-
Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon γ and bacterial tipopolysaccharide
-
Xie, Q., R. Whisnant, and C. Nathan. 1993. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon γ and bacterial tipopolysaccharide. J. Exp. Med. 177:1779.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1779
-
-
Xie, Q.1
Whisnant, R.2
Nathan, C.3
-
20
-
-
0026442689
-
Tumor necrosis factor-α-dependent production of reactive nitrogen intermediates mediates IFN-γ plus IL-2-induced murine macrophage tumoricidal activity
-
Cox, G. W., G. Melillo, U. Chattopadhyay, D. Mullet, R. H. Fertel, and L. Varesio. 1992. Tumor necrosis factor-α-dependent production of reactive nitrogen intermediates mediates IFN-γ plus IL-2-induced murine macrophage tumoricidal activity. J. Immunol. 149:3290.
-
(1992)
J. Immunol.
, vol.149
, pp. 3290
-
-
Cox, G.W.1
Melillo, G.2
Chattopadhyay, U.3
Mullet, D.4
Fertel, R.H.5
Varesio, L.6
-
21
-
-
0027368278
-
Macrophage nitric oxide synthase gene: Two upstream regions mediate induction by interferon γ and lipopolysaccharide
-
Lowenstein, C. J., E. W. Alley, P. Raval, A. D. Snowman, S. H. Snyder, S. W. Russell, and W. J. Murphy. 1993. Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon γ and lipopolysaccharide. Proc. Natl. Acad. Sci. USA 90:9730.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 9730
-
-
Lowenstein, C.J.1
Alley, E.W.2
Raval, P.3
Snowman, A.D.4
Snyder, S.H.5
Russell, S.W.6
Murphy, W.J.7
-
22
-
-
0028348307
-
Requirement for transcription factor IRF-1 in NO synthase induction in macrophages
-
Kamijo, R., H. Harada, T. Matsuyama, M. Bosland, J. Gerecitano, D. Shapiro, J. Le, S. I. Koh, T. Kimura, S. Green, T. W. Mak, T. Taniguchi, and J. Vilcek. 1994. Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science 263:1612.
-
(1994)
Science
, vol.263
, pp. 1612
-
-
Kamijo, R.1
Harada, H.2
Matsuyama, T.3
Bosland, M.4
Gerecitano, J.5
Shapiro, D.6
Le, J.7
Koh, S.I.8
Kimura, T.9
Green, S.10
Mak, T.W.11
Taniguchi, T.12
Vilcek, J.13
-
23
-
-
0028106830
-
Role of interferon regulatory factor 1 in induction of nitric oxide synthase
-
Martin, E., C. Nathan, and Q. W. Xie. 1994. Role of interferon regulatory factor 1 in induction of nitric oxide synthase. J. Exp. Med. 180:977.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 977
-
-
Martin, E.1
Nathan, C.2
Xie, Q.W.3
-
24
-
-
13344282731
-
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
-
Meraz, M. A., J. M. White, K. C. F. Sheenan, E. A. Bach, S. J. Rodig, A. C. Greenlund, D. Campbell, K. Carver-Moore, R. N. DuBois, R. Clark, M. Aguet, and R. D. Schreiber. 1996. Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84:431.
-
(1996)
Cell
, vol.84
, pp. 431
-
-
Meraz, M.A.1
White, J.M.2
Sheenan, K.C.F.3
Bach, E.A.4
Rodig, S.J.5
Greenlund, A.C.6
Campbell, D.7
Carver-Moore, K.8
DuBois, R.N.9
Clark, R.10
Aguet, M.11
Schreiber, R.D.12
-
25
-
-
0029901302
-
Differential dysregulation of nitric oxide production in macrophages with targeted disruptions of IFN regulatory factor-1 and -2 genes
-
Salkowski, C. A., S. A. Barber, G. R. Detore, and S. N. Vogel. 1996. Differential dysregulation of nitric oxide production in macrophages with targeted disruptions of IFN regulatory factor-1 and -2 genes. J. Immunol. 156:3107.
-
(1996)
J. Immunol.
, vol.156
, pp. 3107
-
-
Salkowski, C.A.1
Barber, S.A.2
Detore, G.R.3
Vogel, S.N.4
-
26
-
-
0027939931
-
Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase
-
Xie, Q.-W., Y. Kashiwabara, and C. Nathan. 1994. Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase. J. Biol. Chem. 269:4705.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 4705
-
-
Xie, Q.-W.1
Kashiwabara, Y.2
Nathan, C.3
-
27
-
-
0028984578
-
Activation of p42 mapk/erk2 following engagement of TNF receptor CD120a (p55) in mouse macrophages
-
Winston, B. W., and D. W. H. Riches. 1995. Activation of p42 mapk/erk2 following engagement of TNF receptor CD120a (p55) in mouse macrophages. J. Immunol. 155:1525.
-
(1995)
J. Immunol.
, vol.155
, pp. 1525
-
-
Winston, B.W.1
Riches, D.W.H.2
-
28
-
-
0030657873
-
Preferential activation of the p46 isoform of JNK/SAPK in mouse macrophages by TNFα
-
Chan, E. D., B. W. Winston, M. B. Jarpe, M. W. Wynes, and D. W. H. Riches. 1997. Preferential activation of the p46 isoform of JNK/SAPK in mouse macrophages by TNFα. Proc. Natl. Acad. Sci. USA 94:13169.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13169
-
-
Chan, E.D.1
Winston, B.W.2
Jarpe, M.B.3
Wynes, M.W.4
Riches, D.W.H.5
-
29
-
-
0031279104
-
Activation of p38 mapk, MKK3, and MKK4 by tumor necrosis factor-α in mouse bone marrow-derived macrophages
-
Winston, B. W., E. D. Chan, G. L. Johnson, and D. W. H. Riches. 1997. Activation of p38 mapk, MKK3, and MKK4 by tumor necrosis factor-α in mouse bone marrow-derived macrophages. J. Immunol. 159:4491.
-
(1997)
J. Immunol.
, vol.159
, pp. 4491
-
-
Winston, B.W.1
Chan, E.D.2
Johnson, G.L.3
Riches, D.W.H.4
-
30
-
-
0028864350
-
Preferential involvement of MEK1 in the TNFα induced activation of p42 mapk/erk2 in mouse macrophages
-
Winston, B. W., L. K. Remigio, and D. W. H. Riches. 1995. Preferential involvement of MEK1 in the TNFα induced activation of p42 mapk/erk2 in mouse macrophages. J. Biol. Chem. 270:27391.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27391
-
-
Winston, B.W.1
Remigio, L.K.2
Riches, D.W.H.3
-
31
-
-
0028986629
-
TNFα rapidly activates the MEK/MAP kinase cascade in an MEKK-dependent, c-Raf-1-independent fashion in mouse macrophages
-
Winston, B. W., C. A. Lange-Carter, A. M. Gardner, G. L. Johnson, and D. W. H. Riches. 1995. TNFα rapidly activates the MEK/MAP kinase cascade in an MEKK-dependent, c-Raf-1-independent fashion in mouse macrophages. Proc. Natl. Acad. Sci. USA 92:1614.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 1614
-
-
Winston, B.W.1
Lange-Carter, C.A.2
Gardner, A.M.3
Johnson, G.L.4
Riches, D.W.H.5
-
32
-
-
0028327239
-
Functional switching of macrophage responses to TNFα by interferons: Implications for the pleiotropic activities of TNFα
-
Lake, F. R., P. W. Noble, P. M. Henson, and D. W. H. Riches. 1994. Functional switching of macrophage responses to TNFα by interferons: implications for the pleiotropic activities of TNFα. J. Clin. Invest. 93:1661.
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 1661
-
-
Lake, F.R.1
Noble, P.W.2
Henson, P.M.3
Riches, D.W.H.4
-
33
-
-
0031013545
-
Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway
-
Natoli, G., A. Costanzo, A. Ianni, D. J. Templeton, J. R. Woodgett, C. Balsano, and M. Levrero. 1997. Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway. Science 275:200
-
(1997)
Science
, vol.275
, pp. 200
-
-
Natoli, G.1
Costanzo, A.2
Ianni, A.3
Templeton, D.J.4
Woodgett, J.R.5
Balsano, C.6
Levrero, M.7
-
34
-
-
0027423418
-
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
-
Hibi, M., A. Lin, T. Smeal, A. Minden, and M. Karin. 1993. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev. 7:2135.
-
(1993)
Genes Dev.
, vol.7
, pp. 2135
-
-
Hibi, M.1
Lin, A.2
Smeal, T.3
Minden, A.4
Karin, M.5
-
35
-
-
0009482260
-
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
-
Towbin, H., T. Staehelin, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350.
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 4350
-
-
Towbin, H.1
Staehelin, T.2
Gordon, J.3
-
36
-
-
0029166667
-
A synthetic inhibitor of the mitogen-activated protein kinase cascade
-
Dudley, D. T., L. Pang, S. J. Decker, A. J. Bridges, and A. R. Saltiel. 1995. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA 92:7686.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7686
-
-
Dudley, D.T.1
Pang, L.2
Decker, S.J.3
Bridges, A.J.4
Saltiel, A.R.5
-
37
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee, J. C., J. T. Layton, P. C. McDonnel, T. F. Gallagher, S. Kumar, D. Green, D. McNulty, M. J. Blumenthal, J. R. Heys, and S. W. Landvatter. 1994. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372:739.
-
(1994)
Nature
, vol.372
, pp. 739
-
-
Lee, J.C.1
Layton, J.T.2
McDonnel, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
McNulty, D.7
Blumenthal, M.J.8
Heys, J.R.9
Landvatter, S.W.10
-
38
-
-
0028943245
-
Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2
-
Lin, A., A. Minden, H. Martinetto, F.-X. Claret, C. Lange-Carter, F. Mercurio, G. L. Johnson, and M. Karin. 1995. Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2. Science 268:286.
-
(1995)
Science
, vol.268
, pp. 286
-
-
Lin, A.1
Minden, A.2
Martinetto, H.3
Claret, F.-X.4
Lange-Carter, C.5
Mercurio, F.6
Johnson, G.L.7
Karin, M.8
-
39
-
-
0028935974
-
Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms
-
Derijard, B., J. Raingeaud, T. Barrett, I.-H. Wu, J. Han, R. J. Ulevitch, and R. J. Davis. 1995. Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms. Science 267:682.
-
(1995)
Science
, vol.267
, pp. 682
-
-
Derijard, B.1
Raingeaud, J.2
Barrett, T.3
Wu, I.-H.4
Han, J.5
Ulevitch, R.J.6
Davis, R.J.7
-
40
-
-
0028558986
-
Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun
-
Sanchez, I., R. T. Hughes, B. J. Mayer, K. Yee, J. R. Woodgett, J. Avruch, J. M. Kyriakis, and L. I. Zon. 1994. Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature 372:794.
-
(1994)
Nature
, vol.372
, pp. 794
-
-
Sanchez, I.1
Hughes, R.T.2
Mayer, B.J.3
Yee, K.4
Woodgett, J.R.5
Avruch, J.6
Kyriakis, J.M.7
Zon, L.I.8
-
41
-
-
0028099150
-
Signal transduction for nuclear factor-κB activation
-
Suzuki, Y. J., M. Mizuno, and L. Packer. 1994. Signal transduction for nuclear factor-κB activation. J. Immunol. 153:5008.
-
(1994)
J. Immunol.
, vol.153
, pp. 5008
-
-
Suzuki, Y.J.1
Mizuno, M.2
Packer, L.3
-
42
-
-
0027224017
-
Cross-coupling of the NF-κB p65 and Fos/Jun transcription factors produces potentiated biological function
-
Stein, B., A. S. Baldwin, D. W. Ballard, W. C. Greene, P. Angel, and P. Herrlich. 1993. Cross-coupling of the NF-κB p65 and Fos/Jun transcription factors produces potentiated biological function. EMBO J. 12:3879.
-
(1993)
EMBO J.
, vol.12
, pp. 3879
-
-
Stein, B.1
Baldwin, A.S.2
Ballard, D.W.3
Greene, W.C.4
Angel, P.5
Herrlich, P.6
-
43
-
-
0027209915
-
A cooperative interaction between NF-κB and Sp1 is required for HIV-1 enhancer activation
-
Perkins, N. D., N. L. Edwards, C. S. Duckett, A. B. Agranoff, R. M. Schmid, and G. J. Nabel. 1993. A cooperative interaction between NF-κB and Sp1 is required for HIV-1 enhancer activation. EMBO J. 12:3551.
-
(1993)
EMBO J.
, vol.12
, pp. 3551
-
-
Perkins, N.D.1
Edwards, N.L.2
Duckett, C.S.3
Agranoff, A.B.4
Schmid, R.M.5
Nabel, G.J.6
-
44
-
-
0029879315
-
Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating κB enhancer activation
-
Meyer, C. F., X. Wang, C. Chang, D. Templeton and T. H. Tan. 1996. Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating κB enhancer activation. J. Biol. Chem 271:8971.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 8971
-
-
Meyer, C.F.1
Wang, X.2
Chang, C.3
Templeton, D.4
Tan, T.H.5
-
45
-
-
0029947996
-
MEK kinase is involved in tumor necrosis factor α-induced NF-κB activation and degradation of 1κBα
-
Hirano, M., S. Osada, T. Aoki, S. Hirai, M. Hosaka, J. Inoue, and S. Ohno. 1996. MEK kinase is involved in tumor necrosis factor α-induced NF-κB activation and degradation of 1κBα. J. Biol Chem. 271:13234.
-
(1996)
J. Biol Chem.
, vol.271
, pp. 13234
-
-
Hirano, M.1
Osada, S.2
Aoki, T.3
Hirai, S.4
Hosaka, M.5
Inoue, J.6
Ohno, S.7
-
46
-
-
0031285250
-
Activation of the 1κBα kinase complex by MEKK1, a kinase of the JNK pathway
-
Lee, F. S., J. Hagler, Z. J. Chen, and T. Maniatis. 1997. Activation of the 1κBα kinase complex by MEKK1, a kinase of the JNK pathway. Cell 88:213.
-
(1997)
Cell
, vol.88
, pp. 213
-
-
Lee, F.S.1
Hagler, J.2
Chen, Z.J.3
Maniatis, T.4
-
47
-
-
0029860947
-
Evidence for common mechanisms in the transcriptional control of type II nitric oxide synthase in isolated hepatocytes: Requirement of NFκB activation after stimulation with bacterial cell wall products and phorbol esters
-
Diaz-Guerra, M. J. M., M. Velasco, P. Martin-Sanz, and L. Bosca. 1996. Evidence for common mechanisms in the transcriptional control of type II nitric oxide synthase in isolated hepatocytes: requirement of NFκB activation after stimulation with bacterial cell wall products and phorbol esters. J. Biol. Chem. 271:30114.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30114
-
-
Diaz-Guerra, M.J.M.1
Velasco, M.2
Martin-Sanz, P.3
Bosca, L.4
-
48
-
-
0026004501
-
Phosphorylation of c-jun mediated by MAP kinases
-
Pulverer, B. J., J. M. Kyriakis, J. Avruch, E. Nikolakaki, and J. R. Woodgett. 1991. Phosphorylation of c-jun mediated by MAP kinases. Nature 353:670.
-
(1991)
Nature
, vol.353
, pp. 670
-
-
Pulverer, B.J.1
Kyriakis, J.M.2
Avruch, J.3
Nikolakaki, E.4
Woodgett, J.R.5
-
49
-
-
0025788098
-
Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
-
Smeal, T., B. Binetruy, D. A. Mercola, M. Birrer, and M. Karin. 1991. Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature 354:494.
-
(1991)
Nature
, vol.354
, pp. 494
-
-
Smeal, T.1
Binetruy, B.2
Mercola, D.A.3
Birrer, M.4
Karin, M.5
-
50
-
-
0028130213
-
Tumor necrosis factor α stimulates AP-1 activity through prolonged activation of the c-Jun kinase
-
Westwick, J. K., C. Weitzel, A. Minden, M. Karin, and D. A. Brenner. 1994. Tumor necrosis factor α stimulates AP-1 activity through prolonged activation of the c-Jun kinase. J. Biol. Chem. 269:26396.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26396
-
-
Westwick, J.K.1
Weitzel, C.2
Minden, A.3
Karin, M.4
Brenner, D.A.5
-
51
-
-
0027296741
-
Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements
-
Du, W., D. Thanos, and T. Maniatis. 1993. Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements. Cell 74:887.
-
(1993)
Cell
, vol.74
, pp. 887
-
-
Du, W.1
Thanos, D.2
Maniatis, T.3
-
52
-
-
0030712362
-
Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes
-
Da Silva, J., B. Pierrat, J. L. Mary, and W. Lesslauer. 1997. Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes. J. Biol. Chem. 272:28373.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28373
-
-
Da Silva, J.1
Pierrat, B.2
Mary, J.L.3
Lesslauer, W.4
-
53
-
-
0029932759
-
Interleukin-1β-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F
-
Welsh, N. 1996. Interleukin-1β-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F. J. Biol. Chem. 271:8307.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 8307
-
-
Welsh, N.1
-
54
-
-
0029826970
-
c-Rel regulation of IL-2 gene expression may be mediated through activation of AP-1
-
Shapiro, V. S., M. N. Mollenauer, W. C. Greene, and A. Weiss. 1996. c-Rel regulation of IL-2 gene expression may be mediated through activation of AP-1. J. Exp. Med. 184:1663.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1663
-
-
Shapiro, V.S.1
Mollenauer, M.N.2
Greene, W.C.3
Weiss, A.4
-
55
-
-
0030881742
-
Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor α (TNF-α) translation: Glucocorticoids inhibit TNFα translation by blocking JNK-SAPK
-
Swantek, J. L., M. L. Cobb, and T. D. Geppert. 1997. Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor α (TNF-α) translation: glucocorticoids inhibit TNFα translation by blocking JNK-SAPK. Mol. Cell. Biol. 17:6274.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 6274
-
-
Swantek, J.L.1
Cobb, M.L.2
Geppert, T.D.3
-
57
-
-
0030999565
-
Inhibition of protein geranylgeranylation causes a superinduction of nitric-oxide synthase-2 by interleukin-1β in vascular smooth muscle cells
-
Finder, J. D., J. L. Litz, M. A. Blaskovich, T. F. McGuire, Y. Qian, A. D. Hamilton, P. Davies, and S. M. Sebti. 1997. Inhibition of protein geranylgeranylation causes a superinduction of nitric-oxide synthase-2 by interleukin-1β in vascular smooth muscle cells. J. Biol. Chem. 272:13484.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13484
-
-
Finder, J.D.1
Litz, J.L.2
Blaskovich, M.A.3
McGuire, T.F.4
Qian, Y.5
Hamilton, A.D.6
Davies, P.7
Sebti, S.M.8
-
58
-
-
0030026354
-
Regulation of cytokine-inducible nitric oxide synthase in cardiac myocytes and microvascular endothelial cells: Role of extracellular signal-regulated kinases 1 and 2 (ERK1/ERK2) and Stat1α
-
Singh, K., J.-L. Balligand, T. A. Fischer, T. W. Smith, and R. A. Kelly. 1996. Regulation of cytokine-inducible nitric oxide synthase in cardiac myocytes and microvascular endothelial cells: role of extracellular signal-regulated kinases 1 and 2 (ERK1/ERK2) and Stat1α. J. Biol. Chem. 271:1111.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1111
-
-
Singh, K.1
Balligand, J.-L.2
Fischer, T.A.3
Smith, T.W.4
Kelly, R.A.5
-
60
-
-
0032032424
-
Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-α gene expression in endotoxin-stimulaled primary glial cultures
-
Bhat, N. R., P. Zhang, J. C. Lee, and E. L. Hogan. 1998. Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-α gene expression in endotoxin-stimulaled primary glial cultures. J. Neurosci. 18:1633.
-
(1998)
J. Neurosci.
, vol.18
, pp. 1633
-
-
Bhat, N.R.1
Zhang, P.2
Lee, J.C.3
Hogan, E.L.4
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