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Volumn 162, Issue 1, 1999, Pages 415-422

Evaluation of the role of mitogen-activated protein kinases in the expression of inducible nitric oxide synthase by IFN-γ and TNF-α in mouse macrophages

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 6 (4 FLUOROPHENYL) 2,3 DIHYDRO 5 (4 PYRIDYL)IMIDAZO[2,1 B]THIAZOLE; ACETYLCYSTEINE; GAMMA INTERFERON; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE SYNTHASE; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR;

EID: 0032910884     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (141)

References (60)
  • 1
    • 0026323665 scopus 로고
    • Purification of the inducible murine macrophage nitric oxide synthase: Identification as a flavoprotein
    • Hevel, J. M., K. A. White, and M. A. Marletta. 1991. Purification of the inducible murine macrophage nitric oxide synthase: identification as a flavoprotein, J. Biol. Chem. 266:22789.
    • (1991) J. Biol. Chem. , vol.266 , pp. 22789
    • Hevel, J.M.1    White, K.A.2    Marletta, M.A.3
  • 2
    • 0026729267 scopus 로고
    • Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme
    • Lowenstein, C. J., C. S. Glatt, D. S. Bredt, and S. H. Snyder. 1992. Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme. Proc. Natl. Acad. Sci. USA 89:6711.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6711
    • Lowenstein, C.J.1    Glatt, C.S.2    Bredt, D.S.3    Snyder, S.H.4
  • 5
    • 0025609915 scopus 로고
    • Tumor necrosis factor-α synergizes with IFN-γ in mediating killing of Leishmania major through the induction of nitric-oxide
    • Liew, F. Y., Y. Li, and S. Millott. 1990. Tumor necrosis factor-α synergizes with IFN-γ in mediating killing of Leishmania major through the induction of nitric-oxide. J. Immunol. 145:4306.
    • (1990) J. Immunol. , vol.145 , pp. 4306
    • Liew, F.Y.1    Li, Y.2    Millott, S.3
  • 6
    • 0025648446 scopus 로고
    • Leishmania major amastigotes initiate the L-arginine-dependent killing mechanism in IFN-γ-stimulated macrophages by induction of TNF-α
    • Green, S. J., R. M. Crawford, J. T. Hockmeyer, M. S. Meltzer, and C. A. Nacy. 1990. Leishmania major amastigotes initiate the L-arginine-dependent killing mechanism in IFN-γ-stimulated macrophages by induction of TNF-α. J. Immunol. 145:4290.
    • (1990) J. Immunol. , vol.145 , pp. 4290
    • Green, S.J.1    Crawford, R.M.2    Hockmeyer, J.T.3    Meltzer, M.S.4    Nacy, C.A.5
  • 7
    • 0026549480 scopus 로고
    • Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages
    • Chan, J., Y. Xing, R. S. Magliozzo, and B. R. Bloom. 1992. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J. Exp. Med. 175:1111.
    • (1992) J. Exp. Med. , vol.175 , pp. 1111
    • Chan, J.1    Xing, Y.2    Magliozzo, R.S.3    Bloom, B.R.4
  • 9
    • 0027459588 scopus 로고
    • Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing
    • Lorsbach, R. B., W. J. Murphy, C. J. Lowenstein, S. H. Snyder, and S. W. Russell. 1993. Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. J. Biol. Chem. 268:1908.
    • (1993) J. Biol. Chem. , vol.268 , pp. 1908
    • Lorsbach, R.B.1    Murphy, W.J.2    Lowenstein, C.J.3    Snyder, S.H.4    Russell, S.W.5
  • 11
    • 0028270719 scopus 로고
    • Regulation of biosynthesis of nitric oxide
    • Nathan, C., and Q. W. Xie. 1994. Regulation of biosynthesis of nitric oxide. J. Biol. Chem. 269:13725.
    • (1994) J. Biol. Chem. , vol.269 , pp. 13725
    • Nathan, C.1    Xie, Q.W.2
  • 12
    • 0023408236 scopus 로고
    • Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: Precursors and role of the respiratory burst
    • Iyengar, R., D. J. Stuehr, and M. A. Marletta. 1987. Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst. Proc. Natl. Acad. Sci. USA 84:6369.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 6369
    • Iyengar, R.1    Stuehr, D.J.2    Marletta, M.A.3
  • 13
    • 0023706894 scopus 로고
    • Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages: Comparison of activating cytokines and evidence for independent production
    • Ding, A. H., C. F. Nathan, and D. J. Stuehr. 1988. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages: comparison of activating cytokines and evidence for independent production. J. Immunol. 141:2407.
    • (1988) J. Immunol. , vol.141 , pp. 2407
    • Ding, A.H.1    Nathan, C.F.2    Stuehr, D.J.3
  • 14
    • 0023796162 scopus 로고
    • Interferon-γ and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages
    • Drapier, J. C., J. Wietzerbin, and J. B. J. Hibbs. 1988. Interferon-γ and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages. Eur. J. Immunol. 18:1587.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 1587
    • Drapier, J.C.1    Wietzerbin, J.2    Hibbs, J.B.J.3
  • 15
    • 0028061860 scopus 로고
    • Synergistic cooperation between phorbol ester and IFN-γ for induction of nitric oxide synthesis in murine peritoneal macrophages
    • Jun, C. D., B. M. Choi, H. Ryu, J. Y. Um, H. J. Kwak, B. S. Lee, S. G. Paik, H. M. Kim, and H. T. Chung. 1994. Synergistic cooperation between phorbol ester and IFN-γ for induction of nitric oxide synthesis in murine peritoneal macrophages. J. Immunol. 153:3684.
    • (1994) J. Immunol. , vol.153 , pp. 3684
    • Jun, C.D.1    Choi, B.M.2    Ryu, H.3    Um, J.Y.4    Kwak, H.J.5    Lee, B.S.6    Paik, S.G.7    Kim, H.M.8    Chung, H.T.9
  • 16
    • 0028243464 scopus 로고
    • Regulation of nitric-oxide synthase mRNA expression by interferon-γ and picolinic acid
    • Melillo, G., G. W. Cox, A. Biragyn, L. A. Sheffler, and L. Varesio. 1994. Regulation of nitric-oxide synthase mRNA expression by interferon-γ and picolinic acid. J. Biol. Chem. 269:8128.
    • (1994) J. Biol. Chem. , vol.269 , pp. 8128
    • Melillo, G.1    Cox, G.W.2    Biragyn, A.3    Sheffler, L.A.4    Varesio, L.5
  • 17
    • 0028786601 scopus 로고
    • A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
    • Melillo, G., T. Musso, A. Sica, L. S. Taylor, G. W. Cox, and L. Varesio. 1995. A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J. Exp. Med. 182:1683.
    • (1995) J. Exp. Med. , vol.182 , pp. 1683
    • Melillo, G.1    Musso, T.2    Sica, A.3    Taylor, L.S.4    Cox, G.W.5    Varesio, L.6
  • 18
    • 0030587161 scopus 로고    scopus 로고
    • Regulation of inducible nitric oxide synthase expression in IFN-γ-treated murine macrophages cultured under hypoxic conditions
    • Melillo, G., L. S. Taylor, A. Brooks, G. W. Cox, and L. Varesio. 1996. Regulation of inducible nitric oxide synthase expression in IFN-γ-treated murine macrophages cultured under hypoxic conditions. J. Immunol. 157:2638.
    • (1996) J. Immunol. , vol.157 , pp. 2638
    • Melillo, G.1    Taylor, L.S.2    Brooks, A.3    Cox, G.W.4    Varesio, L.5
  • 19
    • 0027255749 scopus 로고
    • Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon γ and bacterial tipopolysaccharide
    • Xie, Q., R. Whisnant, and C. Nathan. 1993. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon γ and bacterial tipopolysaccharide. J. Exp. Med. 177:1779.
    • (1993) J. Exp. Med. , vol.177 , pp. 1779
    • Xie, Q.1    Whisnant, R.2    Nathan, C.3
  • 20
    • 0026442689 scopus 로고
    • Tumor necrosis factor-α-dependent production of reactive nitrogen intermediates mediates IFN-γ plus IL-2-induced murine macrophage tumoricidal activity
    • Cox, G. W., G. Melillo, U. Chattopadhyay, D. Mullet, R. H. Fertel, and L. Varesio. 1992. Tumor necrosis factor-α-dependent production of reactive nitrogen intermediates mediates IFN-γ plus IL-2-induced murine macrophage tumoricidal activity. J. Immunol. 149:3290.
    • (1992) J. Immunol. , vol.149 , pp. 3290
    • Cox, G.W.1    Melillo, G.2    Chattopadhyay, U.3    Mullet, D.4    Fertel, R.H.5    Varesio, L.6
  • 23
    • 0028106830 scopus 로고
    • Role of interferon regulatory factor 1 in induction of nitric oxide synthase
    • Martin, E., C. Nathan, and Q. W. Xie. 1994. Role of interferon regulatory factor 1 in induction of nitric oxide synthase. J. Exp. Med. 180:977.
    • (1994) J. Exp. Med. , vol.180 , pp. 977
    • Martin, E.1    Nathan, C.2    Xie, Q.W.3
  • 25
    • 0029901302 scopus 로고    scopus 로고
    • Differential dysregulation of nitric oxide production in macrophages with targeted disruptions of IFN regulatory factor-1 and -2 genes
    • Salkowski, C. A., S. A. Barber, G. R. Detore, and S. N. Vogel. 1996. Differential dysregulation of nitric oxide production in macrophages with targeted disruptions of IFN regulatory factor-1 and -2 genes. J. Immunol. 156:3107.
    • (1996) J. Immunol. , vol.156 , pp. 3107
    • Salkowski, C.A.1    Barber, S.A.2    Detore, G.R.3    Vogel, S.N.4
  • 26
    • 0027939931 scopus 로고
    • Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase
    • Xie, Q.-W., Y. Kashiwabara, and C. Nathan. 1994. Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase. J. Biol. Chem. 269:4705.
    • (1994) J. Biol. Chem. , vol.269 , pp. 4705
    • Xie, Q.-W.1    Kashiwabara, Y.2    Nathan, C.3
  • 27
    • 0028984578 scopus 로고
    • Activation of p42 mapk/erk2 following engagement of TNF receptor CD120a (p55) in mouse macrophages
    • Winston, B. W., and D. W. H. Riches. 1995. Activation of p42 mapk/erk2 following engagement of TNF receptor CD120a (p55) in mouse macrophages. J. Immunol. 155:1525.
    • (1995) J. Immunol. , vol.155 , pp. 1525
    • Winston, B.W.1    Riches, D.W.H.2
  • 29
    • 0031279104 scopus 로고    scopus 로고
    • Activation of p38 mapk, MKK3, and MKK4 by tumor necrosis factor-α in mouse bone marrow-derived macrophages
    • Winston, B. W., E. D. Chan, G. L. Johnson, and D. W. H. Riches. 1997. Activation of p38 mapk, MKK3, and MKK4 by tumor necrosis factor-α in mouse bone marrow-derived macrophages. J. Immunol. 159:4491.
    • (1997) J. Immunol. , vol.159 , pp. 4491
    • Winston, B.W.1    Chan, E.D.2    Johnson, G.L.3    Riches, D.W.H.4
  • 30
    • 0028864350 scopus 로고
    • Preferential involvement of MEK1 in the TNFα induced activation of p42 mapk/erk2 in mouse macrophages
    • Winston, B. W., L. K. Remigio, and D. W. H. Riches. 1995. Preferential involvement of MEK1 in the TNFα induced activation of p42 mapk/erk2 in mouse macrophages. J. Biol. Chem. 270:27391.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27391
    • Winston, B.W.1    Remigio, L.K.2    Riches, D.W.H.3
  • 31
    • 0028986629 scopus 로고
    • TNFα rapidly activates the MEK/MAP kinase cascade in an MEKK-dependent, c-Raf-1-independent fashion in mouse macrophages
    • Winston, B. W., C. A. Lange-Carter, A. M. Gardner, G. L. Johnson, and D. W. H. Riches. 1995. TNFα rapidly activates the MEK/MAP kinase cascade in an MEKK-dependent, c-Raf-1-independent fashion in mouse macrophages. Proc. Natl. Acad. Sci. USA 92:1614.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1614
    • Winston, B.W.1    Lange-Carter, C.A.2    Gardner, A.M.3    Johnson, G.L.4    Riches, D.W.H.5
  • 32
    • 0028327239 scopus 로고
    • Functional switching of macrophage responses to TNFα by interferons: Implications for the pleiotropic activities of TNFα
    • Lake, F. R., P. W. Noble, P. M. Henson, and D. W. H. Riches. 1994. Functional switching of macrophage responses to TNFα by interferons: implications for the pleiotropic activities of TNFα. J. Clin. Invest. 93:1661.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1661
    • Lake, F.R.1    Noble, P.W.2    Henson, P.M.3    Riches, D.W.H.4
  • 34
    • 0027423418 scopus 로고
    • Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
    • Hibi, M., A. Lin, T. Smeal, A. Minden, and M. Karin. 1993. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev. 7:2135.
    • (1993) Genes Dev. , vol.7 , pp. 2135
    • Hibi, M.1    Lin, A.2    Smeal, T.3    Minden, A.4    Karin, M.5
  • 35
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin, H., T. Staehelin, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 4350
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 39
    • 0028935974 scopus 로고
    • Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms
    • Derijard, B., J. Raingeaud, T. Barrett, I.-H. Wu, J. Han, R. J. Ulevitch, and R. J. Davis. 1995. Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms. Science 267:682.
    • (1995) Science , vol.267 , pp. 682
    • Derijard, B.1    Raingeaud, J.2    Barrett, T.3    Wu, I.-H.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 41
    • 0028099150 scopus 로고
    • Signal transduction for nuclear factor-κB activation
    • Suzuki, Y. J., M. Mizuno, and L. Packer. 1994. Signal transduction for nuclear factor-κB activation. J. Immunol. 153:5008.
    • (1994) J. Immunol. , vol.153 , pp. 5008
    • Suzuki, Y.J.1    Mizuno, M.2    Packer, L.3
  • 42
    • 0027224017 scopus 로고
    • Cross-coupling of the NF-κB p65 and Fos/Jun transcription factors produces potentiated biological function
    • Stein, B., A. S. Baldwin, D. W. Ballard, W. C. Greene, P. Angel, and P. Herrlich. 1993. Cross-coupling of the NF-κB p65 and Fos/Jun transcription factors produces potentiated biological function. EMBO J. 12:3879.
    • (1993) EMBO J. , vol.12 , pp. 3879
    • Stein, B.1    Baldwin, A.S.2    Ballard, D.W.3    Greene, W.C.4    Angel, P.5    Herrlich, P.6
  • 43
    • 0027209915 scopus 로고
    • A cooperative interaction between NF-κB and Sp1 is required for HIV-1 enhancer activation
    • Perkins, N. D., N. L. Edwards, C. S. Duckett, A. B. Agranoff, R. M. Schmid, and G. J. Nabel. 1993. A cooperative interaction between NF-κB and Sp1 is required for HIV-1 enhancer activation. EMBO J. 12:3551.
    • (1993) EMBO J. , vol.12 , pp. 3551
    • Perkins, N.D.1    Edwards, N.L.2    Duckett, C.S.3    Agranoff, A.B.4    Schmid, R.M.5    Nabel, G.J.6
  • 44
    • 0029879315 scopus 로고    scopus 로고
    • Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating κB enhancer activation
    • Meyer, C. F., X. Wang, C. Chang, D. Templeton and T. H. Tan. 1996. Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating κB enhancer activation. J. Biol. Chem 271:8971.
    • (1996) J. Biol. Chem , vol.271 , pp. 8971
    • Meyer, C.F.1    Wang, X.2    Chang, C.3    Templeton, D.4    Tan, T.H.5
  • 45
    • 0029947996 scopus 로고    scopus 로고
    • MEK kinase is involved in tumor necrosis factor α-induced NF-κB activation and degradation of 1κBα
    • Hirano, M., S. Osada, T. Aoki, S. Hirai, M. Hosaka, J. Inoue, and S. Ohno. 1996. MEK kinase is involved in tumor necrosis factor α-induced NF-κB activation and degradation of 1κBα. J. Biol Chem. 271:13234.
    • (1996) J. Biol Chem. , vol.271 , pp. 13234
    • Hirano, M.1    Osada, S.2    Aoki, T.3    Hirai, S.4    Hosaka, M.5    Inoue, J.6    Ohno, S.7
  • 46
    • 0031285250 scopus 로고    scopus 로고
    • Activation of the 1κBα kinase complex by MEKK1, a kinase of the JNK pathway
    • Lee, F. S., J. Hagler, Z. J. Chen, and T. Maniatis. 1997. Activation of the 1κBα kinase complex by MEKK1, a kinase of the JNK pathway. Cell 88:213.
    • (1997) Cell , vol.88 , pp. 213
    • Lee, F.S.1    Hagler, J.2    Chen, Z.J.3    Maniatis, T.4
  • 47
    • 0029860947 scopus 로고    scopus 로고
    • Evidence for common mechanisms in the transcriptional control of type II nitric oxide synthase in isolated hepatocytes: Requirement of NFκB activation after stimulation with bacterial cell wall products and phorbol esters
    • Diaz-Guerra, M. J. M., M. Velasco, P. Martin-Sanz, and L. Bosca. 1996. Evidence for common mechanisms in the transcriptional control of type II nitric oxide synthase in isolated hepatocytes: requirement of NFκB activation after stimulation with bacterial cell wall products and phorbol esters. J. Biol. Chem. 271:30114.
    • (1996) J. Biol. Chem. , vol.271 , pp. 30114
    • Diaz-Guerra, M.J.M.1    Velasco, M.2    Martin-Sanz, P.3    Bosca, L.4
  • 49
    • 0025788098 scopus 로고
    • Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
    • Smeal, T., B. Binetruy, D. A. Mercola, M. Birrer, and M. Karin. 1991. Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature 354:494.
    • (1991) Nature , vol.354 , pp. 494
    • Smeal, T.1    Binetruy, B.2    Mercola, D.A.3    Birrer, M.4    Karin, M.5
  • 50
    • 0028130213 scopus 로고
    • Tumor necrosis factor α stimulates AP-1 activity through prolonged activation of the c-Jun kinase
    • Westwick, J. K., C. Weitzel, A. Minden, M. Karin, and D. A. Brenner. 1994. Tumor necrosis factor α stimulates AP-1 activity through prolonged activation of the c-Jun kinase. J. Biol. Chem. 269:26396.
    • (1994) J. Biol. Chem. , vol.269 , pp. 26396
    • Westwick, J.K.1    Weitzel, C.2    Minden, A.3    Karin, M.4    Brenner, D.A.5
  • 51
    • 0027296741 scopus 로고
    • Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements
    • Du, W., D. Thanos, and T. Maniatis. 1993. Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements. Cell 74:887.
    • (1993) Cell , vol.74 , pp. 887
    • Du, W.1    Thanos, D.2    Maniatis, T.3
  • 52
    • 0030712362 scopus 로고    scopus 로고
    • Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes
    • Da Silva, J., B. Pierrat, J. L. Mary, and W. Lesslauer. 1997. Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes. J. Biol. Chem. 272:28373.
    • (1997) J. Biol. Chem. , vol.272 , pp. 28373
    • Da Silva, J.1    Pierrat, B.2    Mary, J.L.3    Lesslauer, W.4
  • 53
    • 0029932759 scopus 로고    scopus 로고
    • Interleukin-1β-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F
    • Welsh, N. 1996. Interleukin-1β-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F. J. Biol. Chem. 271:8307.
    • (1996) J. Biol. Chem. , vol.271 , pp. 8307
    • Welsh, N.1
  • 54
    • 0029826970 scopus 로고    scopus 로고
    • c-Rel regulation of IL-2 gene expression may be mediated through activation of AP-1
    • Shapiro, V. S., M. N. Mollenauer, W. C. Greene, and A. Weiss. 1996. c-Rel regulation of IL-2 gene expression may be mediated through activation of AP-1. J. Exp. Med. 184:1663.
    • (1996) J. Exp. Med. , vol.184 , pp. 1663
    • Shapiro, V.S.1    Mollenauer, M.N.2    Greene, W.C.3    Weiss, A.4
  • 55
    • 0030881742 scopus 로고    scopus 로고
    • Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor α (TNF-α) translation: Glucocorticoids inhibit TNFα translation by blocking JNK-SAPK
    • Swantek, J. L., M. L. Cobb, and T. D. Geppert. 1997. Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor α (TNF-α) translation: glucocorticoids inhibit TNFα translation by blocking JNK-SAPK. Mol. Cell. Biol. 17:6274.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6274
    • Swantek, J.L.1    Cobb, M.L.2    Geppert, T.D.3
  • 57
    • 0030999565 scopus 로고    scopus 로고
    • Inhibition of protein geranylgeranylation causes a superinduction of nitric-oxide synthase-2 by interleukin-1β in vascular smooth muscle cells
    • Finder, J. D., J. L. Litz, M. A. Blaskovich, T. F. McGuire, Y. Qian, A. D. Hamilton, P. Davies, and S. M. Sebti. 1997. Inhibition of protein geranylgeranylation causes a superinduction of nitric-oxide synthase-2 by interleukin-1β in vascular smooth muscle cells. J. Biol. Chem. 272:13484.
    • (1997) J. Biol. Chem. , vol.272 , pp. 13484
    • Finder, J.D.1    Litz, J.L.2    Blaskovich, M.A.3    McGuire, T.F.4    Qian, Y.5    Hamilton, A.D.6    Davies, P.7    Sebti, S.M.8
  • 58
    • 0030026354 scopus 로고    scopus 로고
    • Regulation of cytokine-inducible nitric oxide synthase in cardiac myocytes and microvascular endothelial cells: Role of extracellular signal-regulated kinases 1 and 2 (ERK1/ERK2) and Stat1α
    • Singh, K., J.-L. Balligand, T. A. Fischer, T. W. Smith, and R. A. Kelly. 1996. Regulation of cytokine-inducible nitric oxide synthase in cardiac myocytes and microvascular endothelial cells: role of extracellular signal-regulated kinases 1 and 2 (ERK1/ERK2) and Stat1α. J. Biol. Chem. 271:1111.
    • (1996) J. Biol. Chem. , vol.271 , pp. 1111
    • Singh, K.1    Balligand, J.-L.2    Fischer, T.A.3    Smith, T.W.4    Kelly, R.A.5
  • 60
    • 0032032424 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-α gene expression in endotoxin-stimulaled primary glial cultures
    • Bhat, N. R., P. Zhang, J. C. Lee, and E. L. Hogan. 1998. Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-α gene expression in endotoxin-stimulaled primary glial cultures. J. Neurosci. 18:1633.
    • (1998) J. Neurosci. , vol.18 , pp. 1633
    • Bhat, N.R.1    Zhang, P.2    Lee, J.C.3    Hogan, E.L.4


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