LPS induction of gene expression in human monocytes

Cellular Signalling

Volumn 13, Issue 2, 2001, Pages 85-94

  Guha, Mausumee ^a   Mackman, Nigel ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

CD14; Endotoxin; LBP; MAPK; Monocytes; NF B; Septic shock; TLR4

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE PYRIDINYL IMIDAZOLE; BACTERIUM LIPOPOLYSACCHARIDE; CD14 ANTIGEN; CELL SURFACE RECEPTOR; CYTOKINE; GENISTEIN; I KAPPA B; IMIDAZOLE DERIVATIVE; LIPOPOLYSACCHARIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PERTUSSIS TOXIN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR; U 0216; UNCLASSIFIED DRUG;

CHEMICAL STRUCTURE; GENE ACTIVATION; GENE EXPRESSION; GENE INDUCTION; GRAM NEGATIVE BACTERIUM; HUMAN; MOLECULAR RECOGNITION; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SEPTIC SHOCK; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD14; ANTIGENS, SURFACE; DROSOPHILA PROTEINS; HUMANS; LIPOPOLYSACCHARIDES; LYMPHOCYTE ANTIGEN 96; MAP KINASE SIGNALING SYSTEM; MEMBRANE GLYCOPROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; MONOCYTES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN BINDING; RECEPTORS, CELL SURFACE; SEPSIS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

NEGIBACTERIA;

EID: 0035104119     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0898-6568(00)00149-2     Document Type: Review

References (152)

1. Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site