-
1
-
-
0029987839
-
The instructive role of innate immunity in the acquired immune response
-
Fearon D.T., Locksley R.M. The instructive role of innate immunity in the acquired immune response. Science. 272:1996;50-53.
-
(1996)
Science
, vol.272
, pp. 50-53
-
-
Fearon, D.T.1
Locksley, R.M.2
-
2
-
-
0033591428
-
Phylogenetic perspectives in innate immunity
-
This review summarizes our current knowledge on innate immunity mechanisms in insects and mammals
-
Hoffmann J.A., Kafatos F.C., Janeway C.A., Ezekowitz R.A. Phylogenetic perspectives in innate immunity. Science. 284:1999;1313-1318. This review summarizes our current knowledge on innate immunity mechanisms in insects and mammals.
-
(1999)
Science
, vol.284
, pp. 1313-1318
-
-
Hoffmann, J.A.1
Kafatos, F.C.2
Janeway, C.A.3
Ezekowitz, R.A.4
-
3
-
-
0030595339
-
The dorsoventral regulatory gene cassette spaetzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre B., Nicolas E., Michaut L., Reichhart J.M., Hoffmann J.A. The dorsoventral regulatory gene cassette spaetzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 86:1996;973-983.
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.M.4
Hoffmann, J.A.5
-
4
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R., Preston-Hurlburt P., Janeway C. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature. 388:1997;394-397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway, C.3
-
5
-
-
0031905311
-
A family of human receptors structurally related to Drosophila Toll
-
Rock F., Hardiman G., Timans J., Kastelein R., Bazan J. A family of human receptors structurally related to Drosophila Toll. Proc Natl Acad Sci USA. 95:1998;588-593.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 588-593
-
-
Rock, F.1
Hardiman, G.2
Timans, J.3
Kastelein, R.4
Bazan, J.5
-
6
-
-
0032100444
-
Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: Evidence for a multi-gene receptor family in humans
-
Chaudhary P.M., Ferguson C., Nguyen V., Nguyen O., Massa H.F., Eby M., Jasmin A., Trask B.J., Hood L., Nelson P.S. Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans. Blood. 91:1998;4020-4027.
-
(1998)
Blood
, vol.91
, pp. 4020-4027
-
-
Chaudhary, P.M.1
Ferguson, C.2
Nguyen, V.3
Nguyen, O.4
Massa, H.F.5
Eby, M.6
Jasmin, A.7
Trask, B.J.8
Hood, L.9
Nelson, P.S.10
-
8
-
-
0032473360
-
A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway
-
This paper reveals that surface epithelia of Drosophila can be induced to express the antifungal peptide drosomycin
-
Ferrandon D., Jung A., Criqui M., Lemaitre B., Uttenweiler-Joseph S., Michaut L., Reichhart J.M., Hoffmann J.A. A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway. EMBO J. 17:1998;1217-1227. This paper reveals that surface epithelia of Drosophila can be induced to express the antifungal peptide drosomycin.
-
(1998)
EMBO J
, vol.17
, pp. 1217-1227
-
-
Ferrandon, D.1
Jung, A.2
Criqui, M.3
Lemaitre, B.4
Uttenweiler-Joseph, S.5
Michaut, L.6
Reichhart, J.M.7
Hoffmann, J.A.8
-
10
-
-
0033231380
-
Drosophila cecropin as an antifungal agent
-
Ekengren S., Hultmark D. Drosophila cecropin as an antifungal agent. Insect Biochem Mol Biol. 29:1999;965-972.
-
(1999)
Insect Biochem Mol Biol
, vol.29
, pp. 965-972
-
-
Ekengren, S.1
Hultmark, D.2
-
11
-
-
0031446642
-
Drosophila host defense: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms
-
Lemaitre B., Reichhart J.M., Hoffmann J.A. Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proc Natl Acad Sci USA. 94:1997;14614-14619.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14614-14619
-
-
Lemaitre, B.1
Reichhart, J.M.2
Hoffmann, J.A.3
-
12
-
-
0027220975
-
κb-like motifs regulate the induction of immune genes in Drosophila
-
Engstrom Y., Kadayalil L., Sun S., Samakovlis C., Hultmark D., Faye I. κB-like motifs regulate the induction of immune genes in Drosophila. J Mol Biol. 232:1993;327-333.
-
(1993)
J Mol Biol
, vol.232
, pp. 327-333
-
-
Engstrom, Y.1
Kadayalil, L.2
Sun, S.3
Samakovlis, C.4
Hultmark, D.5
Faye, I.6
-
13
-
-
0028559509
-
Insect immunity. A transgenic analysis in Drosophila defines several functional domains in the diptericin promoter
-
Meister M., Braun A., Kappler C., Reichhart J.M., Hoffmann J.A. Insect immunity. A transgenic analysis in Drosophila defines several functional domains in the diptericin promoter. EMBO J. 13:1994;5958-5966.
-
(1994)
EMBO J
, vol.13
, pp. 5958-5966
-
-
Meister, M.1
Braun, A.2
Kappler, C.3
Reichhart, J.M.4
Hoffmann, J.A.5
-
14
-
-
0029730738
-
A conserved signaling pathway: The Drosophila Toll-dorsal pathway
-
Belvin M.P., Anderson K.V. A conserved signaling pathway: the Drosophila Toll-dorsal pathway. Ann Rev Cell Dev Biol. 12:1996;393-416.
-
(1996)
Ann Rev Cell Dev Biol
, vol.12
, pp. 393-416
-
-
Belvin, M.P.1
Anderson, K.V.2
-
15
-
-
0031897632
-
NF-κB and Rel proteins: Evolutionarily conserved mediators of immune responses
-
Ghosh S., May M.J., Kopp E.B. NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol. 16:1998;225-260.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
16
-
-
0032562285
-
In vivo regulation of the IκB homologue cactus during the immune response of Drosophila
-
Nicolas E., Reichhart J.M., Hoffmann J.A., Lemaitre B. In vivo regulation of the IκB homologue cactus during the immune response of Drosophila. J Biol Chem. 273:1998;10463-10469.
-
(1998)
J Biol Chem
, vol.273
, pp. 10463-10469
-
-
Nicolas, E.1
Reichhart, J.M.2
Hoffmann, J.A.3
Lemaitre, B.4
-
17
-
-
0028865526
-
A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense
-
Lemaitre B., Kromer-Metzger E., Michaut L., Nicolas E., Meister M., Georgel P., Reichhart J.M., Hoffmann J.A. A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense. Proc Natl Acad Sci USA. 92:1995;9365-9469.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9365-9469
-
-
Lemaitre, B.1
Kromer-Metzger, E.2
Michaut, L.3
Nicolas, E.4
Meister, M.5
Georgel, P.6
Reichhart, J.M.7
Hoffmann, J.A.8
-
18
-
-
0032485392
-
Regulated nuclear import of Rel proteins in the Drosophila immune response
-
This report presents the identification of a set of immune response deficiency (ird) mutants in which synthesis of the antibacterial peptide diptericin is reduced or abolished
-
Wu L.P., Anderson K.V. Regulated nuclear import of Rel proteins in the Drosophila immune response. Nature. 392:1998;93-97. This report presents the identification of a set of immune response deficiency (ird) mutants in which synthesis of the antibacterial peptide diptericin is reduced or abolished.
-
(1998)
Nature
, vol.392
, pp. 93-97
-
-
Wu, L.P.1
Anderson, K.V.2
-
19
-
-
0032496389
-
Two distinct pathways can control expression of the Drosophila antimicrobial peptide metchnikowin
-
This paper reports that metchnikowin, a peptide with both antibacterial and antifungal activities, is regulated independently by the Toll and the imd pathways
-
Levashina E.A., Ohresser S., Lemaitre B., Imler J.L. Two distinct pathways can control expression of the Drosophila antimicrobial peptide metchnikowin. J Mol Biol. 278:1998;515-527. This paper reports that metchnikowin, a peptide with both antibacterial and antifungal activities, is regulated independently by the Toll and the imd pathways.
-
(1998)
J Mol Biol
, vol.278
, pp. 515-527
-
-
Levashina, E.A.1
Ohresser, S.2
Lemaitre, B.3
Imler, J.L.4
-
20
-
-
0030663332
-
The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense
-
Williams M., Rodriguez A., Kimbrell D., Eldon E. The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense. EMBO J. 16:1997;6120-6130.
-
(1997)
EMBO J
, vol.16
, pp. 6120-6130
-
-
Williams, M.1
Rodriguez, A.2
Kimbrell, D.3
Eldon, E.4
-
21
-
-
0033522129
-
Dorsal-B, a splice variant of the Drosophila factor Dorsal, is a novel Rel/NF-κB transcriptional activator
-
Gross I., Georgel P., Oertel-Buchheit P., Schnarr M., Reichhart J.M. Dorsal-B, a splice variant of the Drosophila factor Dorsal, is a novel Rel/NF-κB transcriptional activator. Gene. 228:1999;233-242.
-
(1999)
Gene
, vol.228
, pp. 233-242
-
-
Gross, I.1
Georgel, P.2
Oertel-Buchheit, P.3
Schnarr, M.4
Reichhart, J.M.5
-
22
-
-
0027443688
-
Dif, a dorsal-related gene that mediates an immune response in Drosophila
-
Ip Y., Reach M., Enstrom Y., Kadalayil L., Cai H., Gonzalez-Crespo S., Tatei K., Levine M. Dif, a dorsal-related gene that mediates an immune response in Drosophila. Cell. 75:1993;753-763.
-
(1993)
Cell
, vol.75
, pp. 753-763
-
-
Ip, Y.1
Reach, M.2
Enstrom, Y.3
Kadalayil, L.4
Cai, H.5
Gonzalez-Crespo, S.6
Tatei, K.7
Levine, M.8
-
23
-
-
0029840669
-
Origins of immunity: Relish, a compound Rel-like gene in the antibacterial defense of Drosophila
-
Dushay M., Asling B., Hultmark D. Origins of immunity: Relish, a compound Rel-like gene in the antibacterial defense of Drosophila. Proc Natl Acad Sci USA. 93:1996;10343-10347.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10343-10347
-
-
Dushay, M.1
Asling, B.2
Hultmark, D.3
-
24
-
-
0028877993
-
Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila
-
Lemaitre B., Meister M., Govind S., Georgel P., Steward R., Reichhart J.M., Hoffmann J.A. Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila. EMBO J. 14:1995;536-545.
-
(1995)
EMBO J
, vol.14
, pp. 536-545
-
-
Lemaitre, B.1
Meister, M.2
Govind, S.3
Georgel, P.4
Steward, R.5
Reichhart, J.M.6
Hoffmann, J.A.7
-
25
-
-
0033118490
-
Toll receptor-mediated Drosophila immune response requires Dif, an NF-κB factor
-
This paper shows that Dif is involved in the induction of drosomycin and defensin during the immune response in Drosophila adults
-
Meng X., Khanuja B.S., Ip Y.T. Toll receptor-mediated Drosophila immune response requires Dif, an NF-κB factor. Genes Dev. 13:1999;792-797. This paper shows that Dif is involved in the induction of drosomycin and defensin during the immune response in Drosophila adults.
-
(1999)
Genes Dev
, vol.13
, pp. 792-797
-
-
Meng, X.1
Khanuja, B.S.2
Ip, Y.T.3
-
26
-
-
0033564614
-
A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF
-
This paper shows that Dorsal and Dif have a redundant function in the control of drosomycin induction during the immune response in Drosophila larvae
-
Manfruelli P., Reichhart J.M., Steward R., Hoffmann J.A., Lemaitre B. A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF. EMBO J. 18:1999;3380-3391. This paper shows that Dorsal and Dif have a redundant function in the control of drosomycin induction during the immune response in Drosophila larvae.
-
(1999)
EMBO J
, vol.18
, pp. 3380-3391
-
-
Manfruelli, P.1
Reichhart, J.M.2
Steward, R.3
Hoffmann, J.A.4
Lemaitre, B.5
-
27
-
-
0033231556
-
Relish, a central factor in the control of humoral but not cellular immunity in Drosophila
-
This report presents the characterization of relish mutants and shows that inducibility of all antimicrobial peptides upon bacterial challenge is strongly reduced in the absence of Relish
-
Hedengren M., Asling B., Dushay M., Ando I., Ekengren S., Wihlborg M., Hultmark D. Relish, a central factor in the control of humoral but not cellular immunity in Drosophila. Mol Cell. 4:1999;827-837. This report presents the characterization of relish mutants and shows that inducibility of all antimicrobial peptides upon bacterial challenge is strongly reduced in the absence of Relish.
-
(1999)
Mol Cell
, vol.4
, pp. 827-837
-
-
Hedengren, M.1
Asling, B.2
Dushay, M.3
Ando, I.4
Ekengren, S.5
Wihlborg, M.6
Hultmark, D.7
-
28
-
-
0033597935
-
Interaction and specificity of Rel-related proteins in regulating Drosophila immunity gene expression
-
This report shows that overexpression of various combinations of Dif, Dorsal and Relish factors in transfected cells results in differential levels of induction of antimicrobial peptide genes
-
Han Z.S., Ip Y.T. Interaction and specificity of Rel-related proteins in regulating Drosophila immunity gene expression. J Biol Chem. 274:1999;21355-21361. This report shows that overexpression of various combinations of Dif, Dorsal and Relish factors in transfected cells results in differential levels of induction of antimicrobial peptide genes.
-
(1999)
J Biol Chem
, vol.274
, pp. 21355-21361
-
-
Han, Z.S.1
Ip, Y.T.2
-
29
-
-
0028075756
-
Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo
-
Grosshans J., Bergmann A., Haffter P., Nüsslein-Volhard C. Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo. Nature. 372:1994;563-566.
-
(1994)
Nature
, vol.372
, pp. 563-566
-
-
Grosshans, J.1
Bergmann, A.2
Haffter, P.3
Nüsslein-Volhard, C.4
-
30
-
-
0029007386
-
Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos
-
Galindo R.L., Edwards D.N., Gillespie S.K., Wasserman S.A. Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos. Development. 121:1995;2209-2218.
-
(1995)
Development
, vol.121
, pp. 2209-2218
-
-
Galindo, R.L.1
Edwards, D.N.2
Gillespie, S.K.3
Wasserman, S.A.4
-
31
-
-
0029925960
-
Functional interactions between the pelle kinase, Toll receptor, and tube suggest a mechanism for activation of dorsal
-
Norris J.L., Manley J.L. Functional interactions between the pelle kinase, Toll receptor, and tube suggest a mechanism for activation of dorsal. Genes Dev. 10:1996;862-872.
-
(1996)
Genes Dev
, vol.10
, pp. 862-872
-
-
Norris, J.L.1
Manley, J.L.2
-
32
-
-
0033601077
-
Three-dimensional structure of a complex between the death domains of Pelle and Tube
-
Xiao T., Towb P., Wasserman S.A., Sprang S.R. Three-dimensional structure of a complex between the death domains of Pelle and Tube. Cell. 99:1999;545-555.
-
(1999)
Cell
, vol.99
, pp. 545-555
-
-
Xiao, T.1
Towb, P.2
Wasserman, S.A.3
Sprang, S.R.4
-
33
-
-
0026030444
-
Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity
-
Letsou A., Alexander S., Orth K., Wasserman S.A. Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity. Proc Natl Acad Sci USA. 88:1991;810-814.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 810-814
-
-
Letsou, A.1
Alexander, S.2
Orth, K.3
Wasserman, S.A.4
-
34
-
-
0030815382
-
An activity-dependent network of interactions links the Rel protein Dorsal with its cytoplasmic regulators
-
Edwards D.N., Towb P., Wasserman S.A. An activity-dependent network of interactions links the Rel protein Dorsal with its cytoplasmic regulators. Development. 124:1997;3855-3864.
-
(1997)
Development
, vol.124
, pp. 3855-3864
-
-
Edwards, D.N.1
Towb, P.2
Wasserman, S.A.3
-
35
-
-
0031901916
-
Recruitment of Tube and Pelle to signaling sites at the surface of the Drosophila embryo
-
Towb P., Galindo R.L., Wasserman S.A. Recruitment of Tube and Pelle to signaling sites at the surface of the Drosophila embryo. Development. 125:1998;2443-2450.
-
(1998)
Development
, vol.125
, pp. 2443-2450
-
-
Towb, P.1
Galindo, R.L.2
Wasserman, S.A.3
-
36
-
-
0032415862
-
Phosphorylation modulates direct interactions between the Toll receptor, Pelle kinase and Tube
-
Shen B., Manley J.L. Phosphorylation modulates direct interactions between the Toll receptor, Pelle kinase and Tube. Development. 125:1998;4719-4728.
-
(1998)
Development
, vol.125
, pp. 4719-4728
-
-
Shen, B.1
Manley, J.L.2
-
37
-
-
0032934595
-
Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal
-
Grosshans J., Schnorrer F., Nusslein-Volhard C. Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal. Mech Dev. 81:1999;127-138.
-
(1999)
Mech Dev
, vol.81
, pp. 127-138
-
-
Grosshans, J.1
Schnorrer, F.2
Nusslein-Volhard, C.3
-
38
-
-
0030694108
-
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
-
Muzio M., Ni J., Feng P., Dixit V.M. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science. 278:1997;1612-1615.
-
(1997)
Science
, vol.278
, pp. 1612-1615
-
-
Muzio, M.1
Ni, J.2
Feng, P.3
Dixit, V.M.4
-
39
-
-
0031423761
-
MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
-
Wesche H., Henzel W.J., Shillinglaw W., Li S., Cao Z. MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. Immunity. 7:1997;837-847.
-
(1997)
Immunity
, vol.7
, pp. 837-847
-
-
Wesche, H.1
Henzel, W.J.2
Shillinglaw, W.3
Li, S.4
Cao, Z.5
-
40
-
-
0032133278
-
MyD88, is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
-
Medzhitov R., Preston-Hurlburt P., Kopp E., Stadlen A., Chen C., Ghosh S., Janeway C.A. Jr. MyD88, is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol Cell. 2:1998;253-258.
-
(1998)
Mol Cell
, vol.2
, pp. 253-258
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Kopp, E.3
Stadlen, A.4
Chen, C.5
Ghosh, S.6
Janeway C.A., Jr.7
-
41
-
-
0029865142
-
IRAK: A kinase associated with the interleukin-1 receptor
-
Cao Z., Henzel W., Gao X. IRAK: a kinase associated with the interleukin-1 receptor. Science. 271:1996;1128-1131.
-
(1996)
Science
, vol.271
, pp. 1128-1131
-
-
Cao, Z.1
Henzel, W.2
Gao, X.3
-
42
-
-
0029905275
-
Developmental and tissue specific expression of a mouse Pelle-like protein kinase
-
Trofimova M., Sprenkle A., Green M., Sturgill T., Goebl M., Harrington M. Developmental and tissue specific expression of a mouse Pelle-like protein kinase. J Biol Chem. 271:1996;17609-17612.
-
(1996)
J Biol Chem
, vol.271
, pp. 17609-17612
-
-
Trofimova, M.1
Sprenkle, A.2
Green, M.3
Sturgill, T.4
Goebl, M.5
Harrington, M.6
-
43
-
-
0033067894
-
The Toll-receptor family and control of innate immunity
-
Kopp E.B., Medzhitov R. The Toll-receptor family and control of innate immunity. Curr Opin Immunol. 11:1999;13-18.
-
(1999)
Curr Opin Immunol
, vol.11
, pp. 13-18
-
-
Kopp, E.B.1
Medzhitov, R.2
-
44
-
-
0033611551
-
A Drosophila TNF-receptor-associated factor (TRAF) binds the ste20 kinase Misshapen and activates Jun kinase
-
Liu H., Su Y.C., Becker E., Treisman J., Skolnik E.Y. A Drosophila TNF-receptor-associated factor (TRAF) binds the ste20 kinase Misshapen and activates Jun kinase. Curr Biol. 9:1999;101-104.
-
(1999)
Curr Biol
, vol.9
, pp. 101-104
-
-
Liu, H.1
Su, Y.C.2
Becker, E.3
Treisman, J.4
Skolnik, E.Y.5
-
45
-
-
0033600604
-
The beginning of the end: IκB kinase (IKK) and NF-κB activation
-
Karin M. The beginning of the end: IκB kinase (IKK) and NF-κB activation. J Biol Chem. 274:1999;27339-27342.
-
(1999)
J Biol Chem
, vol.274
, pp. 27339-27342
-
-
Karin, M.1
-
46
-
-
0032033030
-
Proteolytic processing of the Drosophila Spaetzle protein by easter generates a dimeric NGF-like molecule with ventralising activity
-
Using recombinant proteins, this paper establishes that Spaetzle is cleaved by the protease Easter, thus generating a neurotrophin-like signaling molecule
-
DeLotto Y., DeLotto R. Proteolytic processing of the Drosophila Spaetzle protein by easter generates a dimeric NGF-like molecule with ventralising activity. Mech Dev. 72:1998;141-148. Using recombinant proteins, this paper establishes that Spaetzle is cleaved by the protease Easter, thus generating a neurotrophin-like signaling molecule.
-
(1998)
Mech Dev
, vol.72
, pp. 141-148
-
-
Delotto, Y.1
Delotto, R.2
-
47
-
-
0033106265
-
Signal transduction by a protease cascade
-
A well written recent review on the molecular characterization of the proteolytic cascade activating Spaetzle in the Drosophila embryo
-
LeMosy E.K., Hong C.C., Hashimoto C. Signal transduction by a protease cascade. Trends Cell Biol. 9:1999;102-107. A well written recent review on the molecular characterization of the proteolytic cascade activating Spaetzle in the Drosophila embryo.
-
(1999)
Trends Cell Biol
, vol.9
, pp. 102-107
-
-
Lemosy, E.K.1
Hong, C.C.2
Hashimoto, C.3
-
48
-
-
0033578917
-
Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila
-
The first demonstration that Spaetzle is activated by proteolytic cleavage during the immune response in Drosophila
-
Levashina E.A., Langley E., Green C., Gubb D., Ashburner M., Hoffmann J.A., Reichhart J.M. Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila. Science. 285:1999;1917-1919. The first demonstration that Spaetzle is activated by proteolytic cleavage during the immune response in Drosophila.
-
(1999)
Science
, vol.285
, pp. 1917-1919
-
-
Levashina, E.A.1
Langley, E.2
Green, C.3
Gubb, D.4
Ashburner, M.5
Hoffmann, J.A.6
Reichhart, J.M.7
-
49
-
-
0029928757
-
The role of hemolymph coagulation in innate immunity
-
Muta T., Iwanaga S. The role of hemolymph coagulation in innate immunity. Curr Opin Immunol. 8:1996;41-47.
-
(1996)
Curr Opin Immunol
, vol.8
, pp. 41-47
-
-
Muta, T.1
Iwanaga, S.2
-
50
-
-
0003654039
-
Host resistance to infection: Genetic control of lipopolysaccharide responsiveness by TOLL-like receptor genes
-
Qureshi S.T., Gros P., Malo D. Host resistance to infection: genetic control of lipopolysaccharide responsiveness by TOLL-like receptor genes. Trends Genet. 15:1999;291-294.
-
(1999)
Trends Genet
, vol.15
, pp. 291-294
-
-
Qureshi, S.T.1
Gros, P.2
Malo, D.3
-
51
-
-
0033557176
-
Toll, a new piece in the puzzle of innate immunity
-
[comment]
-
Wright S.D. Toll, a new piece in the puzzle of innate immunity. J Exp Med. 189:1999;605-609. [comment].
-
(1999)
J Exp Med
, vol.189
, pp. 605-609
-
-
Wright, S.D.1
-
52
-
-
0033557744
-
Anopheles gambiaei Ag-STAT, a new insect member of the STAT family, is activated in response to bacterial infection
-
The first indication that the JAK-STAT pathway could be involved in host defense reactions in insects
-
Barillas-Mury C., Han Y.S., Seeley D., Kafatos F.C. Anopheles gambiaei Ag-STAT, a new insect member of the STAT family, is activated in response to bacterial infection. EMBO J. 18:1999;959-967. The first indication that the JAK-STAT pathway could be involved in host defense reactions in insects.
-
(1999)
EMBO J
, vol.18
, pp. 959-967
-
-
Barillas-Mury, C.1
Han, Y.S.2
Seeley, D.3
Kafatos, F.C.4
-
53
-
-
0029824847
-
A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila
-
Sluss H.K., Han Z., Barrett T., Davis R.J., Ip Y.T. A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila. Genes Dev. 10:1996;2745-2758.
-
(1996)
Genes Dev
, vol.10
, pp. 2745-2758
-
-
Sluss, H.K.1
Han, Z.2
Barrett, T.3
Davis, R.J.4
Ip, Y.T.5
-
54
-
-
0031866058
-
A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression
-
Han Z.S., Enslen H., Hu X., Meng X., Wu I.H., Barrett T., Davis R.J., Ip Y.T. A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression. Mol Cell Biol. 18:1998;3527-3539.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3527-3539
-
-
Han, Z.S.1
Enslen, H.2
Hu, X.3
Meng, X.4
Wu, I.H.5
Barrett, T.6
Davis, R.J.7
Ip, Y.T.8
-
55
-
-
0032564398
-
Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes
-
This report shows that larvae with a strong hematopoietic defect are more sensitive to infection than their normal counterparts
-
Braun A., Hoffmann J.A., Meister M. Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes. Proc Natl Acad Sci USA. 95:1998;14337-14342. This report shows that larvae with a strong hematopoietic defect are more sensitive to infection than their normal counterparts.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14337-14342
-
-
Braun, A.1
Hoffmann, J.A.2
Meister, M.3
-
56
-
-
0031748547
-
A role for the Drosophila Toll/Cactus pathway in larval hematopoiesis
-
This paper shows that the Toll/cactus gene cassette controls blood cells proliferation and differentiation in Drosophila larvae
-
Qiu P., Pan P.C., Govind S. A role for the Drosophila Toll/Cactus pathway in larval hematopoiesis. Development. 125:1998;1909-1920. This paper shows that the Toll/cactus gene cassette controls blood cells proliferation and differentiation in Drosophila larvae.
-
(1998)
Development
, vol.125
, pp. 1909-1920
-
-
Qiu, P.1
Pan, P.C.2
Govind, S.3
|