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Volumn 64, Issue 2, 1998, Pages 259-264

Endotoxin activation of mitogen-activated protein kinase in THP-1 cells; diminished activation following endotoxin desensitization

Author keywords

ERK; G proteins; Phorbol myristate acetate; Thromboxane A2

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ENDOTOXIN; GUANINE NUCLEOTIDE BINDING PROTEIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; PERTUSSIS TOXIN; PHORBOL 13 ACETATE 12 MYRISTATE; THROMBOXANE A2;

EID: 0031927625     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.64.2.259     Document Type: Article
Times cited : (35)

References (57)
  • 2
    • 0024272982 scopus 로고
    • Cachetin/TNF-alpha in septic shock and septic adult respiratory distress syndrome
    • Tracey, K. J., Lowry, S. F., Cerami, A. (1988) Cachetin/TNF-alpha in septic shock and septic adult respiratory distress syndrome. Am. Rev. Respir. Dis. 138, 1377-1379.
    • (1988) Am. Rev. Respir. Dis. , vol.138 , pp. 1377-1379
    • Tracey, K.J.1    Lowry, S.F.2    Cerami, A.3
  • 3
    • 0001448673 scopus 로고
    • Role of cyclo-oxygenase products in septic shock
    • E. Nuegebauer and J. Holaday, eds.
    • Simmons, T., Halushka, P., Cook, J. (1993) Role of cyclo-oxygenase products in septic shock. In Handbook on Mediators in Septic Shock (E. Nuegebauer and J. Holaday, eds.), 395-418.
    • (1993) Handbook on Mediators in Septic Shock , pp. 395-418
    • Simmons, T.1    Halushka, P.2    Cook, J.3
  • 5
    • 0001394860 scopus 로고
    • Mechanisms of endotoxin tolerance. III. The refractory state during continuous intravenous infusions of endotoxin
    • Greisman, S. E., Woodward, W. E. (1965) Mechanisms of endotoxin tolerance. III. The refractory state during continuous intravenous infusions of endotoxin. J. Exp. Med. 121, 911-933.
    • (1965) J. Exp. Med. , vol.121 , pp. 911-933
    • Greisman, S.E.1    Woodward, W.E.2
  • 8
    • 0025764159 scopus 로고
    • Preexposure of macrophages to low doses of lipopolysaccharide inhibits the expression of tumor necrosis factor-alpha mRNA but not of IL-1 beta mRNA
    • Takasuka, N., Tokunaga, T., Akagawa, K. S. (1991) Preexposure of macrophages to low doses of lipopolysaccharide inhibits the expression of tumor necrosis factor-alpha mRNA but not of IL-1 beta mRNA. J. Immunol. 146, 3824-3830.
    • (1991) J. Immunol. , vol.146 , pp. 3824-3830
    • Takasuka, N.1    Tokunaga, T.2    Akagawa, K.S.3
  • 9
    • 0029161483 scopus 로고
    • Tolerance to lipopolysaccharide in human blood monocytes
    • Ziegler-Heitbrock, H. W., Frankenberger, M., Wedel, A. (1995) Tolerance to lipopolysaccharide in human blood monocytes. Immunobiol. 193, 217-223.
    • (1995) Immunobiol. , vol.193 , pp. 217-223
    • Ziegler-Heitbrock, H.W.1    Frankenberger, M.2    Wedel, A.3
  • 11
    • 0024842903 scopus 로고
    • Lipopolysaccharide induces hyporesponsiveness to its own action in RAW 264.7 cells
    • Virca, G. D., Kim, S. Y., Glaser, K. B., Ulevitch, R. J. (1989) Lipopolysaccharide induces hyporesponsiveness to its own action in RAW 264.7 cells. J. Biol. Chem. 264, 21951-21956.
    • (1989) J. Biol. Chem. , vol.264 , pp. 21951-21956
    • Virca, G.D.1    Kim, S.Y.2    Glaser, K.B.3    Ulevitch, R.J.4
  • 13
    • 0029895464 scopus 로고    scopus 로고
    • Defective translation of tumor necrosis factor mRNA in lipopolysaccharide-tolerant macrophages
    • Marchant, A., Gueydan, C., Houzet, L., Amraoui, Z., Sels, A., Huez, G., Goldman, M., Kruys, V. (1996) Defective translation of tumor necrosis factor mRNA in lipopolysaccharide-tolerant macrophages. J. Inflamm. 46, 114-123.
    • (1996) J. Inflamm. , vol.46 , pp. 114-123
    • Marchant, A.1    Gueydan, C.2    Houzet, L.3    Amraoui, Z.4    Sels, A.5    Huez, G.6    Goldman, M.7    Kruys, V.8
  • 14
    • 0027451272 scopus 로고
    • Lipopolysaccharide structure-function relationship in activation versus reprogramming of mouse peritoneal macrophages
    • Zhang, X., Morrison, D. C. (1993) Lipopolysaccharide structure-function relationship in activation versus reprogramming of mouse peritoneal macrophages. J. Leukoc. Biol. 54, 444-450.
    • (1993) J. Leukoc. Biol. , vol.54 , pp. 444-450
    • Zhang, X.1    Morrison, D.C.2
  • 15
    • 0028989086 scopus 로고
    • Suppression of TNF-alpha mRNA expression in LPS-primed macrophages occurs at the level of nuclear factor-kappa B activation, but not at the level of protein kinase C or CD14 expression
    • Takasuka, N., Matsuura, K., Yamamoto, S., Akagawa, K. S. (1995) Suppression of TNF-alpha mRNA expression in LPS-primed macrophages occurs at the level of nuclear factor-kappa B activation, but not at the level of protein kinase C or CD14 expression. J. Immunol. 154, 4803-4812.
    • (1995) J. Immunol. , vol.154 , pp. 4803-4812
    • Takasuka, N.1    Matsuura, K.2    Yamamoto, S.3    Akagawa, K.S.4
  • 17
    • 0028440854 scopus 로고
    • Endotoxin tolerance: Effects on lethality and macrophage thromboxane (B2) and interleukin 6 production
    • Chen, H., Halushka, P. V., Cook, J. A. (1994) Endotoxin tolerance: effects on lethality and macrophage thromboxane (B2) and interleukin 6 production. Shock 1, 366-371.
    • (1994) Shock , vol.1 , pp. 366-371
    • Chen, H.1    Halushka, P.V.2    Cook, J.A.3
  • 18
    • 0029249276 scopus 로고
    • Increased nitric oxide synthesis during the development of endotoxin tolerance
    • Zingarelli, B., Halushka, P. V., Caputi, A. P., Cook, J. A. (1995) Increased nitric oxide synthesis during the development of endotoxin tolerance. Shock 3, 102-108.
    • (1995) Shock , vol.3 , pp. 102-108
    • Zingarelli, B.1    Halushka, P.V.2    Caputi, A.P.3    Cook, J.A.4
  • 20
    • 0029148462 scopus 로고
    • Mechanisms of reprogrammed macrophage endotoxin signal transduction after lipopolysaccharide pretreatment
    • West, M. A., Seatter, S. C., Bellingham, J., Clair, L. (1995) Mechanisms of reprogrammed macrophage endotoxin signal transduction after lipopolysaccharide pretreatment. Surgery 118, 220-228.
    • (1995) Surgery , vol.118 , pp. 220-228
    • West, M.A.1    Seatter, S.C.2    Bellingham, J.3    Clair, L.4
  • 22
    • 0029890168 scopus 로고    scopus 로고
    • Endotoxin signal transduction in macrophages
    • Sweet, M., Hume, D. (1996) Endotoxin signal transduction in macrophages. J. Leukoc. Biol. 60, 8-26.
    • (1996) J. Leukoc. Biol. , vol.60 , pp. 8-26
    • Sweet, M.1    Hume, D.2
  • 23
    • 0027424403 scopus 로고
    • Endotoxin induces rapid protein tyrosine phosphorylation in 70Z/3 cells expressing CD14
    • Han, J., Lee, J. D., Tobias, P. S., Ulevitch, R. J. (1993) Endotoxin induces rapid protein tyrosine phosphorylation in 70Z/3 cells expressing CD14. J. Biol. Chem. 268, 25009-25014.
    • (1993) J. Biol. Chem. , vol.268 , pp. 25009-25014
    • Han, J.1    Lee, J.D.2    Tobias, P.S.3    Ulevitch, R.J.4
  • 24
    • 0025879557 scopus 로고
    • Endotoxin-induced arachidonic acid metabolism requires de novo protein synthesis and protein kinase C activation
    • Geisel, J., Cook, J. A., Coffee, K. A., Wise, W. C., Halushka, P. V. (1991) Endotoxin-induced arachidonic acid metabolism requires de novo protein synthesis and protein kinase C activation. Biochim. Biophys. Acta 1085, 15-20.
    • (1991) Biochim. Biophys. Acta , vol.1085 , pp. 15-20
    • Geisel, J.1    Cook, J.A.2    Coffee, K.A.3    Wise, W.C.4    Halushka, P.V.5
  • 25
    • 84973824945 scopus 로고
    • Endotoxin tolerance is not a LPS-specific phenomenon: Partial mimicry with IL-1, IL-10, and TGFβ
    • Cavaillon, J., Pitton, C., Fitting, C. (1994) Endotoxin tolerance is not a LPS-specific phenomenon: partial mimicry with IL-1, IL-10, and TGFβ. J. Endotoxin Res. 1, 21-29.
    • (1994) J. Endotoxin Res. , vol.1 , pp. 21-29
    • Cavaillon, J.1    Pitton, C.2    Fitting, C.3
  • 26
    • 0028068084 scopus 로고
    • Involvement of protein kinase C and protein tyrosine kinase in lipopolysaccharide-induced TNF-alpha and IL-1 beta production by human monocytes
    • Shapira, L., Takashiba, S., Champagne, C., Amar, S., Van Dyke, T. E. (1994) Involvement of protein kinase C and protein tyrosine kinase in lipopolysaccharide-induced TNF-alpha and IL-1 beta production by human monocytes. J. Immunol. 153, 1818-1824.
    • (1994) J. Immunol. , vol.153 , pp. 1818-1824
    • Shapira, L.1    Takashiba, S.2    Champagne, C.3    Amar, S.4    Van Dyke, T.E.5
  • 27
    • 0025076237 scopus 로고
    • Altered responses to modulators of guanine nucleotide binding protein activity in endotoxin tolerance
    • Coffee, K. A., Halushka, P. V., Wise, W. C., Cook, J. A. (1990) Altered responses to modulators of guanine nucleotide binding protein activity in endotoxin tolerance. Biochim. Biophys. Acta 1035, 201-205.
    • (1990) Biochim. Biophys. Acta , vol.1035 , pp. 201-205
    • Coffee, K.A.1    Halushka, P.V.2    Wise, W.C.3    Cook, J.A.4
  • 28
    • 0030927529 scopus 로고    scopus 로고
    • Endotoxin-induced desensitization of THP-1 cells is not associated with altered G protein binding or content
    • Durando, M., Makhlouf, M., Simmons-Wagner, R., Halushka, P., Cook J. (1997) Endotoxin-induced desensitization of THP-1 cells is not associated with altered G protein binding or content. J. Endotoxin Res. 4, 97-103.
    • (1997) J. Endotoxin Res. , vol.4 , pp. 97-103
    • Durando, M.1    Makhlouf, M.2    Simmons-Wagner, R.3    Halushka, P.4    Cook, J.5
  • 30
    • 0028261211 scopus 로고
    • Lipopolysaccharide-mediated signal transduction through phospholipase D activation in monocytic cell lines
    • Natarajan, V., Iwamoto, G. K. (1994) Lipopolysaccharide-mediated signal transduction through phospholipase D activation in monocytic cell lines. Biochim. Biophys. Acta 1213, 14-20.
    • (1994) Biochim. Biophys. Acta , vol.1213 , pp. 14-20
    • Natarajan, V.1    Iwamoto, G.K.2
  • 31
    • 0028535921 scopus 로고
    • Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the Ras/Raf-1/MEK/MAPK pathway
    • Geppert, D., Whitehurst, C., Thompson, P., Beutler, B. (1994) Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the Ras/Raf-1/MEK/MAPK pathway. Mol. Med. 1, 93-103.
    • (1994) Mol. Med. , vol.1 , pp. 93-103
    • Geppert, D.1    Whitehurst, C.2    Thompson, P.3    Beutler, B.4
  • 32
    • 0027296047 scopus 로고
    • Lipopolysaccharide-induced protein tyrosine phosphorylation in human macrophages is mediated by CD14
    • Weinstein, S. L., June, C. H., De Franco, A. L. (1993) Lipopolysaccharide-induced protein tyrosine phosphorylation in human macrophages is mediated by CD14. J. Immunol. 151, 3829-3838.
    • (1993) J. Immunol. , vol.151 , pp. 3829-3838
    • Weinstein, S.L.1    June, C.H.2    De Franco, A.L.3
  • 33
    • 0027144465 scopus 로고
    • Protein tyrosine kinase activation is required for lipopolysaccharide induction of cytokines in human blood monocytes
    • Geng, Y., Zhang, B., Lotz, M. (1993) Protein tyrosine kinase activation is required for lipopolysaccharide induction of cytokines in human blood monocytes. J. Immunol. 151, 6692-6700.
    • (1993) J. Immunol. , vol.151 , pp. 6692-6700
    • Geng, Y.1    Zhang, B.2    Lotz, M.3
  • 34
    • 0026659881 scopus 로고
    • Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophages
    • Weinstein, S. L., Sanghera, J. S., Lemke, K., De Franco, A. L., Pelech, S. L. (1992) Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophages. J. Biol. Chem. 267, 14955-14962.
    • (1992) J. Biol. Chem. , vol.267 , pp. 14955-14962
    • Weinstein, S.L.1    Sanghera, J.S.2    Lemke, K.3    De Franco, A.L.4    Pelech, S.L.5
  • 35
    • 0028099853 scopus 로고
    • Signaling pathways mediated by the mitogen-activated protein (MAP) kinase kinase/MAP kinase cascade
    • Matsuda, S., Gotoh, Y., Nishida, E. (1994) Signaling pathways mediated by the mitogen-activated protein (MAP) kinase kinase/MAP kinase cascade. J. Leukoc. Biol. 56, 548-553.
    • (1994) J. Leukoc. Biol. , vol.56 , pp. 548-553
    • Matsuda, S.1    Gotoh, Y.2    Nishida, E.3
  • 36
    • 0027171230 scopus 로고
    • Desensitization of macrophages to endotoxin effects is not correlated with a down-regulation of lipopolysaccharide-binding sites
    • Fahmi, H., Chaby, R. (1993) Desensitization of macrophages to endotoxin effects is not correlated with a down-regulation of lipopolysaccharide-binding sites. Cell Immunol. 150, 219-229.
    • (1993) Cell Immunol. , vol.150 , pp. 219-229
    • Fahmi, H.1    Chaby, R.2
  • 37
    • 0032062331 scopus 로고    scopus 로고
    • Suppressed thromboxane production in endotoxin-desensitized THP-1 cells is not a result of decreased prostaglandin H synthetase activity
    • in press
    • Durando, M., Fernando, L., Ashton, S., Halushka, P. V., Cook, J. A. (1998) Suppressed thromboxane production in endotoxin-desensitized THP-1 cells is not a result of decreased prostaglandin H synthetase activity. Shock in press.
    • (1998) Shock
    • Durando, M.1    Fernando, L.2    Ashton, S.3    Halushka, P.V.4    Cook, J.A.5
  • 38
    • 0031059229 scopus 로고    scopus 로고
    • LPS pretreatment reprograms macrophage LPS-stimulated TNF and IL-1 release without protein tyrosine kinase activation
    • West, B., Seatter, Clair, Bellingham (1997) LPS pretreatment reprograms macrophage LPS-stimulated TNF and IL-1 release without protein tyrosine kinase activation. J. Leukoc. Biol. 61, 88-95.
    • (1997) J. Leukoc. Biol. , vol.61 , pp. 88-95
    • West, B.1    Seatter2    Clair3    Bellingham4
  • 39
    • 0028176297 scopus 로고
    • cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells
    • Faure, M., Voyno-Yasenetskaya, T. A., Bourne, H. R. (1994) cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells. J. Biol. Chem. 269, 7851-7854.
    • (1994) J. Biol. Chem. , vol.269 , pp. 7851-7854
    • Faure, M.1    Voyno-Yasenetskaya, T.A.2    Bourne, H.R.3
  • 40
    • 0028240869 scopus 로고
    • Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits
    • Crespo, P., Xu, N., Simonds, W. F., Gutkind, J. S. (1994) Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits [see comments]. Nature 369, 418-420.
    • (1994) Nature , vol.369 , pp. 418-420
    • Crespo, P.1    Xu, N.2    Simonds, W.F.3    Gutkind, J.S.4
  • 41
    • 0028971687 scopus 로고
    • Gi2-mediated activation of the MAP kinase cascade
    • Pace, A. M., Faure, M., Bourne, H. R. (1995) Gi2-mediated activation of the MAP kinase cascade. Mol. Biol. Cell 6, 1685-1695.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 1685-1695
    • Pace, A.M.1    Faure, M.2    Bourne, H.R.3
  • 42
    • 0029892373 scopus 로고    scopus 로고
    • Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors
    • Wan, Y., Kurosaki, T., Huang, X. Y. (1996) Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors. Nature 380, 541-544.
    • (1996) Nature , vol.380 , pp. 541-544
    • Wan, Y.1    Kurosaki, T.2    Huang, X.Y.3
  • 43
    • 0027967441 scopus 로고
    • A labile transcriptional repressor modulates endotoxin tolerance
    • LaRue, K. E., McCall, C. E. (1994) A labile transcriptional repressor modulates endotoxin tolerance. J. Coop. Med. 180, 2269-2275.
    • (1994) J. Coop. Med. , vol.180 , pp. 2269-2275
    • Larue, K.E.1    McCall, C.E.2
  • 44
    • 0022477274 scopus 로고
    • Differential alteration of lipoxygenase and cyclooxygenase metabolism by rat peritoneal macrophages induced by endotoxin tolerance
    • Rogers, T. S., Halushka, P. V., Wise, W. C., Cook, J. A. (1986) Differential alteration of lipoxygenase and cyclooxygenase metabolism by rat peritoneal macrophages induced by endotoxin tolerance. Prostaglandins 31, 639-650.
    • (1986) Prostaglandins , vol.31 , pp. 639-650
    • Rogers, T.S.1    Halushka, P.V.2    Wise, W.C.3    Cook, J.A.4
  • 46
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • Alessi, D. R., Cuenda, A., Cohen, P., Dudley, D. T., Saltiel, A. R. (1995) PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270, 27489-27494.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 48
    • 0027936755 scopus 로고
    • A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
    • Han, J., Lee, J. D., Bibbs, L., Ulevitch, R. J. (1994) A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265, 808-811.
    • (1994) Science , vol.265 , pp. 808-811
    • Han, J.1    Lee, J.D.2    Bibbs, L.3    Ulevitch, R.J.4
  • 49
    • 0028036746 scopus 로고
    • Lipopolysaccharide induces activation of the Raf-1/MAP kinase pathway. A putative role for Raf-1 in the induction of the IL-1 beta and the TNF-alpha genes
    • Reimann, T., Buscher, D., Hipskind, R. A., Krautwald, S., Lohmann-Matthes, M. L., Baccarini, M. (1994) Lipopolysaccharide induces activation of the Raf-1/MAP kinase pathway. A putative role for Raf-1 in the induction of the IL-1 beta and the TNF-alpha genes. J. Immunol. 153, 5740-5749.
    • (1994) J. Immunol. , vol.153 , pp. 5740-5749
    • Reimann, T.1    Buscher, D.2    Hipskind, R.A.3    Krautwald, S.4    Lohmann-Matthes, M.L.5    Baccarini, M.6
  • 50
    • 0029054963 scopus 로고
    • Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events
    • Hambleton, J., McMahon, M., De Franco, A. L. (1995) Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events. J. Exp. Med. 182, 147-154.
    • (1995) J. Exp. Med. , vol.182 , pp. 147-154
    • Hambleton, J.1    McMahon, M.2    De Franco, A.L.3
  • 51
    • 0028129888 scopus 로고
    • CD14-dependent activation of protein kinase C and mitogen-activated protein kinases (p42 and p44) in human monocytes treated with bacterial lipopolysaccharide
    • Liu, M. K., Herrera-Velit, P., Brownsey, R. W., Reiner, N. E. (1994) CD14-dependent activation of protein kinase C and mitogen-activated protein kinases (p42 and p44) in human monocytes treated with bacterial lipopolysaccharide. J. Immunol. 153, 2642-2652.
    • (1994) J. Immunol. , vol.153 , pp. 2642-2652
    • Liu, M.K.1    Herrera-Velit, P.2    Brownsey, R.W.3    Reiner, N.E.4
  • 52
    • 0028906437 scopus 로고
    • Production of tumor necrosis factor induced by synthetic low-toxicity lipid A analog, DT-5461a, is mediated by LPS receptor sites and tyrosine kinase-MAP kinase signaling pathway in murine macrophages
    • Joto, N., Akimoto, T., Someya, K., Tohgo, A. (1995) Production of tumor necrosis factor induced by synthetic low-toxicity lipid A analog, DT-5461a, is mediated by LPS receptor sites and tyrosine kinase-MAP kinase signaling pathway in murine macrophages. Cell Immunol. 160, 1-7.
    • (1995) Cell Immunol. , vol.160 , pp. 1-7
    • Joto, N.1    Akimoto, T.2    Someya, K.3    Tohgo, A.4
  • 53
    • 0030045535 scopus 로고    scopus 로고
    • Differential induction of the mitogen-activated protein kinase pathway by bacterial lipopolysaccharide in cultured monocytes and astrocytes
    • Willis, S. A., Nisen, P. D. (1996) Differential induction of the mitogen-activated protein kinase pathway by bacterial lipopolysaccharide in cultured monocytes and astrocytes. Biochem. J. 313, 519-524.
    • (1996) Biochem. J. , vol.313 , pp. 519-524
    • Willis, S.A.1    Nisen, P.D.2
  • 54
    • 0029028786 scopus 로고
    • G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein
    • Touhara, K., Hawes, B. E., van Biesen, T., Lefkowitz, R. J. (1995) G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein. Proc. Natl. Acad. Sci. USA 92, 9284-9287.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9284-9287
    • Touhara, K.1    Hawes, B.E.2    Van Biesen, T.3    Lefkowitz, R.J.4
  • 55
    • 0029778177 scopus 로고    scopus 로고
    • Role of c-Src tyrosine kinase in G protein-coupled receptor- and βγ subunit-mediated activation of mitogen-activated protein kinases
    • Luttrell, L. M., Hawes, B. E., van Biesen, T., Luttrell, D. K., Lansing, T. J., Lefkowitz, R. J. (1996) Role of c-Src tyrosine kinase in G protein-coupled receptor-and βγ subunit-mediated activation of mitogen-activated protein kinases. J. Biol. Chem. 271, 19443-19450.
    • (1996) J. Biol. Chem. , vol.271 , pp. 19443-19450
    • Luttrell, L.M.1    Hawes, B.E.2    Van Biesen, T.3    Luttrell, D.K.4    Lansing, T.J.5    Lefkowitz, R.J.6
  • 56
    • 0027424403 scopus 로고
    • Endotoxin induces rapid protein tyrosine phosphorylation in 70Z/3 cells expressing CD14
    • Han, J., Lee, J. D., Tobias, P. S., Ulevitch, R. J. (1993) Endotoxin induces rapid protein tyrosine phosphorylation in 70Z/3 cells expressing CD14. J. Biol. Chem. 268, 25009-2514.
    • (1993) J. Biol. Chem. , vol.268 , pp. 25009-32514
    • Han, J.1    Lee, J.D.2    Tobias, P.S.3    Ulevitch, R.J.4
  • 57
    • 0028364801 scopus 로고
    • Lipopolysaccharide-induced cytokine production in human monocytes: Role of tyrosine phosphorylation in transmembrane signal transduction
    • Beaty, C. D., Franklin, T. L., Uehara, Y., Wilson, C. B. (1994) Lipopolysaccharide-induced cytokine production in human monocytes: role of tyrosine phosphorylation in transmembrane signal transduction. Eur. J. Immunol. 24, 1278-1284.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1278-1284
    • Beaty, C.D.1    Franklin, T.L.2    Uehara, Y.3    Wilson, C.B.4


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