Impact of age on hypermutation of immunoglobulin variable genes in humans

Journal of Clinical Immunology

Volumn 21, Issue 2, 2001, Pages 102-115

  Rosner, K ^a   Winter, D B ^a   Kasmer, C ^a   Skovgaard, G L ^b   Tarone, R E ^c   Bohr, V A ^a   Gearhart, P J ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b Rigshospitalet   (Denmark)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Aging; Antibody selection; Hypermutation; Immunoglobulin genes; Mismatch repair

Indexed keywords

COMPLEMENTARY DNA; IMMUNOGLOBULIN; IMMUNOGLOBULIN HEAVY CHAIN; MICROSATELLITE DNA;

ADULT; AGED; AGING; ARTICLE; B LYMPHOCYTE; DNA SEQUENCE; GENE LOCATION; GENE MUTATION; HUMAN; HUMAN EXPERIMENT; IMMUNOGLOBULIN VARIABLE REGION; MICROSATELLITE INSTABILITY; MOLECULAR CLONING; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; AGING; BASE SEQUENCE; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR SEQUENCE DATA; MUTATION;

EID: 0035045853     PISSN: 02719142     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011003821798     Document Type: Article

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