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Volumn 89, Issue 4, 1997, Pages 1288-1298

Evidence for a large compartment of IgM-expressing memory B cells in humans

Author keywords

[No Author keywords available]

Indexed keywords

CD23 ANTIGEN; CD38 ANTIGEN; GLOBOTRIAOSYLCERAMIDE; IMMUNOGLOBULIN D; IMMUNOGLOBULIN M;

EID: 1842405428     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v89.4.1288     Document Type: Article
Times cited : (282)

References (77)
  • 2
    • 0027260343 scopus 로고
    • The maturation of the immune response
    • Berek C, Ziegner M: The maturation of the immune response. Immunol Today 14:400, 1993
    • (1993) Immunol Today , vol.14 , pp. 400
    • Berek, C.1    Ziegner, M.2
  • 3
    • 0026060620 scopus 로고
    • Intraclonal generation of antibody mutants in germinal centers
    • Jacob J, Kelsoe G, Rajewsky K, Weiss U: Intraclonal generation of antibody mutants in germinal centers. Nature 354:389, 1991
    • (1991) Nature , vol.354 , pp. 389
    • Jacob, J.1    Kelsoe, G.2    Rajewsky, K.3    Weiss, U.4
  • 4
    • 0027491651 scopus 로고
    • Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections
    • Küppers R, Zhao M, Hansmann M-L, Rajewsky K: Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections. EMBO J 12:4955, 1993
    • (1993) EMBO J , vol.12 , pp. 4955
    • Küppers, R.1    Zhao, M.2    Hansmann, M.-L.3    Rajewsky, K.4
  • 5
    • 0026331458 scopus 로고
    • Maturation of the immune response in germinal centers
    • Berek C, Berger A, Apel M: Maturation of the immune response in germinal centers. Cell 67:1121, 1991
    • (1991) Cell , vol.67 , pp. 1121
    • Berek, C.1    Berger, A.2    Apel, M.3
  • 6
    • 0025601012 scopus 로고
    • The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response
    • Weiss U, Rajewsky K: The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response. J Exp Med 172:1681, 1990
    • (1990) J Exp Med , vol.172 , pp. 1681
    • Weiss, U.1    Rajewsky, K.2
  • 7
    • 0023103574 scopus 로고
    • Isolation of high-affinity memory B cells: Phycoerythrin as a probe for antigen-binding cells
    • Hayakawa K, Ishii R, Yamasaki K, Kishimoto T, Hardy RR: Isolation of high-affinity memory B cells: Phycoerythrin as a probe for antigen-binding cells. Proc Natl Acad Sci USA 84:1379, 1987
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 1379
    • Hayakawa, K.1    Ishii, R.2    Yamasaki, K.3    Kishimoto, T.4    Hardy, R.R.5
  • 8
    • 0024989657 scopus 로고
    • Maintenance of B-cell memory by long-lived cells generated from proliferating precursors
    • Schittek B, Rajewsky K: Maintenance of B-cell memory by long-lived cells generated from proliferating precursors. Nature 346:749, 1990
    • (1990) Nature , vol.346 , pp. 749
    • Schittek, B.1    Rajewsky, K.2
  • 9
    • 0026647158 scopus 로고
    • Natural occurrence and origin of somatically mutated memory B cells in mice
    • Schittek B, Rajewsky K: Natural occurrence and origin of somatically mutated memory B cells in mice. J Exp Med 176:427, 1992
    • (1992) J Exp Med , vol.176 , pp. 427
    • Schittek, B.1    Rajewsky, K.2
  • 10
    • 0013803936 scopus 로고
    • Antigens in immunity. VII. Analysis of immunological memory
    • Nossal GJV, Austin CM, Ada GL: Antigens in immunity. VII. Analysis of immunological memory. Immunology 9:333, 1965
    • (1965) Immunology , vol.9 , pp. 333
    • Nossal, G.J.V.1    Austin, C.M.2    Ada, G.L.3
  • 11
    • 1842319040 scopus 로고
    • Immunological memory of IgM and IgG type antibodies. I. Requirements of antigen dose for induction and of time interval for development of memory
    • Valentova V, Cerny J, Ivanyi J: Immunological memory of IgM and IgG type antibodies. I. Requirements of antigen dose for induction and of time interval for development of memory. Folia Biol 13:101, 1967
    • (1967) Folia Biol , vol.13 , pp. 101
    • Valentova, V.1    Cerny, J.2    Ivanyi, J.3
  • 12
    • 0014881986 scopus 로고
    • Determination of antibody class in a system of cooperating antigenic determinants
    • Schirrmacher V, Rajewsky K: Determination of antibody class in a system of cooperating antigenic determinants. J Exp Med 132:1019, 1970
    • (1970) J Exp Med , vol.132 , pp. 1019
    • Schirrmacher, V.1    Rajewsky, K.2
  • 13
    • 0025107997 scopus 로고
    • Heavy-chain class switch does not terminate somatic mutation
    • Shan H, Shlomchik M, Weigert M: Heavy-chain class switch does not terminate somatic mutation. J Exp Med 172:531, 1990
    • (1990) J Exp Med , vol.172 , pp. 531
    • Shan, H.1    Shlomchik, M.2    Weigert, M.3
  • 14
    • 0026786650 scopus 로고
    • High frequency of somatically mutated IgM molecules in the human adult B cell repertoire
    • Van Es JH, Gmelig-Meyling FHJ, Logtenberg T: High frequency of somatically mutated IgM molecules in the human adult B cell repertoire. Eur J Immunol 22: 2761, 1992
    • (1992) Eur J Immunol , vol.22 , pp. 2761
    • Van Es, J.H.1    Gmelig-Meyling, F.H.J.2    Logtenberg, T.3
  • 15
    • 0026772275 scopus 로고
    • Immunoglobulin heavy chain gene expression in peripheral blood B lymphocytes
    • Huang C, Steward AK, Schwartz RS, Stollar BD: Immunoglobulin heavy chain gene expression in peripheral blood B lymphocytes. J Clin Invest 89:1331, 1992
    • (1992) J Clin Invest , vol.89 , pp. 1331
    • Huang, C.1    Steward, A.K.2    Schwartz, R.S.3    Stollar, B.D.4
  • 16
    • 0027420437 scopus 로고
    • κ genes with no or little somatic mutation throughout life
    • κ genes with no or little somatic mutation throughout life. Eur J Immunol 23:3272, 1993
    • (1993) Eur J Immunol , vol.23 , pp. 3272
    • Klein, U.1    Küppers, R.2    Rajewsky, K.3
  • 17
    • 0027382370 scopus 로고
    • A majority of Ig H chain cDNA of normal human adult blood lymphocytes resembles cDNA for fetal Ig and natural autoantibodies
    • Huang C, Stollar BD: A majority of Ig H chain cDNA of normal human adult blood lymphocytes resembles cDNA for fetal Ig and natural autoantibodies. J Immunol 151:5290, 1993
    • (1993) J Immunol , vol.151 , pp. 5290
    • Huang, C.1    Stollar, B.D.2
  • 19
    • 0022630009 scopus 로고
    • Human peripheral blood B lymphocyte subpopulations: Functional and phenotypic analysis of surface IgD positive and negative subsets
    • Jelinek DF, Splawski JB, Lipsky PE: Human peripheral blood B lymphocyte subpopulations: Functional and phenotypic analysis of surface IgD positive and negative subsets. J Immunol 136:83, 1986
    • (1986) J Immunol , vol.136 , pp. 83
    • Jelinek, D.F.1    Splawski, J.B.2    Lipsky, P.E.3
  • 20
    • 0025351843 scopus 로고
    • A phenotypic study of B lymphocyte subpopulations in human bone marrow
    • Chapple MR, MacLennan ICM, Johnson GD: A phenotypic study of B lymphocyte subpopulations in human bone marrow. Clin Exp Immunol 81:166, 1990
    • (1990) Clin Exp Immunol , vol.81 , pp. 166
    • Chapple, M.R.1    MacLennan, I.C.M.2    Johnson, G.D.3
  • 21
    • 0016738010 scopus 로고
    • Rapid flow cytometric analysis of mammalian cell cycle by propidium iodide staining
    • Krishan A: Rapid flow cytometric analysis of mammalian cell cycle by propidium iodide staining. J Cell Biol 66:188, 1975
    • (1975) J Cell Biol , vol.66 , pp. 188
    • Krishan, A.1
  • 22
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N: Single-step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156, 1987
    • (1987) Anal Biochem , vol.162 , pp. 156
    • Chomczynski, P.1    Sacchi, N.2
  • 23
    • 0027753103 scopus 로고
    • Detection of clonal B cell populations in paraffin-embedded tissues by polymerase chain reaction
    • Küppers R, Zhao M, Rajewsky K, Hansmann M-L: Detection of clonal B cell populations in paraffin-embedded tissues by polymerase chain reaction. Am J Pathol 143:230, 1993
    • (1993) Am J Pathol , vol.143 , pp. 230
    • Küppers, R.1    Zhao, M.2    Rajewsky, K.3    Hansmann, M.-L.4
  • 25
    • 0027198854 scopus 로고
    • Cell cycle regulation of the glyceraldehyde-3-phosphate dehydrogenase/ uracil DNA glycosylase gene in normal human cells
    • Mansur NR, Meyer-Siegler K, Wurzer JC, Sirover MA: Cell cycle regulation of the glyceraldehyde-3-phosphate dehydrogenase/ uracil DNA glycosylase gene in normal human cells. Nucleic Acids Res 21:993, 1993
    • (1993) Nucleic Acids Res , vol.21 , pp. 993
    • Mansur, N.R.1    Meyer-Siegler, K.2    Wurzer, J.C.3    Sirover, M.A.4
  • 26
  • 27
    • 0027688019 scopus 로고
    • The variable region genes of the human immunoglobulin κ locus
    • Schäble KF, Zachau HG: The variable region genes of the human immunoglobulin κ locus. Biol Chem Hoppe Seyler 374:1001, 1993
    • (1993) Biol Chem Hoppe Seyler , vol.374 , pp. 1001
    • Schäble, K.F.1    Zachau, H.G.2
  • 28
    • 0028964162 scopus 로고
    • Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid upregulation of B7.1 and B7.2
    • Liu Y-J, Barthelemy C, de Bouteiller O, Arpin C, Durand I, Banchereau J: Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid upregulation of B7.1 and B7.2. Immunity 2:239, 1995
    • (1995) Immunity , vol.2 , pp. 239
    • Liu, Y.-J.1    Barthelemy, C.2    De Bouteiller, O.3    Arpin, C.4    Durand, I.5    Banchereau, J.6
  • 30
    • 0028270307 scopus 로고
    • Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/ matrix attachment region
    • Betz AG, Milstein C, Gonzalez-Fernandez A, Pannell R, Larson T, Neuberger MS: Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/ matrix attachment region. Cell 77:239, 1994
    • (1994) Cell , vol.77 , pp. 239
    • Betz, A.G.1    Milstein, C.2    Gonzalez-Fernandez, A.3    Pannell, R.4    Larson, T.5    Neuberger, M.S.6
  • 33
    • 0020051098 scopus 로고
    • Evolution of immunoglobulin κ J region genes
    • Hieter PA, Maizel JV, Leder P: Evolution of immunoglobulin κ J region genes. J Biol Chem 257:1516, 1982
    • (1982) J Biol Chem , vol.257 , pp. 1516
    • Hieter, P.A.1    Maizel, J.V.2    Leder, P.3
  • 35
    • 0021948168 scopus 로고
    • Interleukin 2 receptors on human B cells. Implications for the role of interleukin 2 in human B cell function
    • Muraguchi A, Kehrl JH, Longo DL, Volkman DJ, Smith KA, Fauci AS: Interleukin 2 receptors on human B cells. Implications for the role of interleukin 2 in human B cell function. J Exp Med 161:181, 1985
    • (1985) J Exp Med , vol.161 , pp. 181
    • Muraguchi, A.1    Kehrl, J.H.2    Longo, D.L.3    Volkman, D.J.4    Smith, K.A.5    Fauci, A.S.6
  • 36
    • 0002530934 scopus 로고
    • Cluster report: CD71
    • Knapp H, Dörken B, Gilks WR, Rieber EP, Schmidt RE, Stein H, Von dem Borne AEG (eds): Oxford, UK, Oxford
    • Schwarting R, Stein H: Cluster report: CD71, in Knapp H, Dörken B, Gilks WR, Rieber EP, Schmidt RE, Stein H, Von dem Borne AEG (eds): Leucocyte Typing IV. White Cell Differentiation Antigens. Oxford, UK, Oxford, 1990, p 455
    • (1990) Leucocyte Typing IV. White Cell Differentiation Antigens , pp. 455
    • Schwarting, R.1    Stein, H.2
  • 38
    • 0022931319 scopus 로고
    • Phenotypic and functional characterization of human LEU1 (CD5) B cells
    • Gadol N, Ault KA: Phenotypic and functional characterization of human LEU1 (CD5) B cells. Immunol Rev 93:23, 1986
    • (1986) Immunol Rev , vol.93 , pp. 23
    • Gadol, N.1    Ault, K.A.2
  • 40
    • 0023046863 scopus 로고
    • Transcriptional and posttranscriptional control of immunoglobulin mRNA production during B lymphocyte development
    • Kelley DE, Perry RP: Transcriptional and posttranscriptional control of immunoglobulin mRNA production during B lymphocyte development. Nucleic Acids Res 14:5431, 1986
    • (1986) Nucleic Acids Res , vol.14 , pp. 5431
    • Kelley, D.E.1    Perry, R.P.2
  • 42
    • 0020606415 scopus 로고
    • B4, a human B lymphocyte-associated antigen expressed on normal, mitogen-activaied, and malignant B lymphocytes
    • Nadler LM, Andersen KC, Marti G, Bates M, Park E, Daley JF, Schlossmann SF: B4, a human B lymphocyte-associated antigen expressed on normal, mitogen-activaied, and malignant B lymphocytes. J Immunol 131:244, 1983
    • (1983) J Immunol , vol.131 , pp. 244
    • Nadler, L.M.1    Andersen, K.C.2    Marti, G.3    Bates, M.4    Park, E.5    Daley, J.F.6    Schlossmann, S.F.7
  • 46
    • 0028180135 scopus 로고
    • κIII gene usage is nonstochastic in both adult and newborn peripheral B cells and that peripheral CDS+ adult B cells are oligoclonal
    • κIII gene usage is nonstochastic in both adult and newborn peripheral B cells and that peripheral CDS+ adult B cells are oligoclonal. J Clin Invest 93:2093, 1994
    • (1994) J Clin Invest , vol.93 , pp. 2093
    • Weber, J.-C.1    Blaison, G.2    Martin, T.3    Knapp, A.-M.4    Pasquali, J.-L.5
  • 47
    • 0029116259 scopus 로고
    • Somatic mutation and CDR3 lengths of immunoglobulin κ light chains expressed in patients with rheumatoid arthritis and in normal individuals
    • Bridges SL Jr, Lee SK, Johnson ML, Lavelle JC, Fowler PG, Koopman WJ, Schroeder HW Jr: Somatic mutation and CDR3 lengths of immunoglobulin κ light chains expressed in patients with rheumatoid arthritis and in normal individuals. J Clin Invest 96:831, 1995
    • (1995) J Clin Invest , vol.96 , pp. 831
    • Bridges Jr., S.L.1    Lee, S.K.2    Johnson, M.L.3    Lavelle, J.C.4    Fowler, P.G.5    Koopman, W.J.6    Schroeder Jr., H.W.7
  • 48
    • 0027428398 scopus 로고
    • Expressed human immunoglobulin κ genes and their hypermutation
    • Klein R, Jaenichen R, Zachau HG: Expressed human immunoglobulin κ genes and their hypermutation. Eur J Immunol 23:3248, 1993
    • (1993) Eur J Immunol , vol.23 , pp. 3248
    • Klein, R.1    Jaenichen, R.2    Zachau, H.G.3
  • 49
    • 0028033316 scopus 로고
    • Variable region gene analysis of B cell subsets derived from a 4-yr-old child: Somatically mutated memory B cells accumulate in the peripheral blood already at young age
    • Klein U, Küppers R, Rajewsky K: Variable region gene analysis of B cell subsets derived from a 4-yr-old child: Somatically mutated memory B cells accumulate in the peripheral blood already at young age. J Exp Med 180:1383, 1994
    • (1994) J Exp Med , vol.180 , pp. 1383
    • Klein, U.1    Küppers, R.2    Rajewsky, K.3
  • 50
    • 0027190704 scopus 로고
    • Isolation of germinal centerlike events from human spleen RNA
    • Varade WS, Insel RA: Isolation of germinal centerlike events from human spleen RNA. J Clin Invest 91:1838, 1993
    • (1993) J Clin Invest , vol.91 , pp. 1838
    • Varade, W.S.1    Insel, R.A.2
  • 52
    • 0027379716 scopus 로고
    • hi splenic B cells are an immature developmental intermediate in the production of long-lived marrow derived B cells
    • hi splenic B cells are an immature developmental intermediate in the production of long-lived marrow derived B cells. J Immunol 151:4431, 1993
    • (1993) J Immunol , vol.151 , pp. 4431
    • Allman, D.M.1    Ferguson, S.E.2    Lentz, V.M.3    Cancro, M.P.4
  • 53
    • 0025432829 scopus 로고
    • B cell development in the bone marrow
    • Osmond DG: B cell development in the bone marrow. Semin Immunol 2:173, 1990
    • (1990) Semin Immunol , vol.2 , pp. 173
    • Osmond, D.G.1
  • 54
    • 0028794835 scopus 로고
    • Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process
    • Reynaud CA, Garcia C, Hein WR, Weill J-C: Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process. Cell 80:115, 1995
    • (1995) Cell , vol.80 , pp. 115
    • Reynaud, C.A.1    Garcia, C.2    Hein, W.R.3    Weill, J.-C.4
  • 55
    • 0025970135 scopus 로고
    • Somatic generation of diversity in a mammalian primary lymphoid organ: The sheep ileal Peyer's patches
    • Reynaud CA, Mackay CR, Müller RG, Weill J-C: Somatic generation of diversity in a mammalian primary lymphoid organ: The sheep ileal Peyer's patches. Cell 64:995, 1991
    • (1991) Cell , vol.64 , pp. 995
    • Reynaud, C.A.1    Mackay, C.R.2    Müller, R.G.3    Weill, J.-C.4
  • 58
    • 0026578234 scopus 로고
    • Cells in the marginal zone of the spleen
    • Kraal G: Cells in the marginal zone of the spleen. Int Rev Cytol 132:31, 1992
    • (1992) Int Rev Cytol , vol.132 , pp. 31
    • Kraal, G.1
  • 59
    • 0029127069 scopus 로고
    • Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells
    • Dunn-Walters DK, Isaacson PG, Spencer J: Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells. J Exp Med 182:559, 1995
    • (1995) J Exp Med , vol.182 , pp. 559
    • Dunn-Walters, D.K.1    Isaacson, P.G.2    Spencer, J.3
  • 60
    • 0023892588 scopus 로고
    • Memory B cells in T cell-dependent antibody responses colonize the splenic marginal zones
    • Liu Y-J, Oldneld S, MacLennan ICM: Memory B cells in T cell-dependent antibody responses colonize the splenic marginal zones. Eur J Immunol 18:355, 1988
    • (1988) Eur J Immunol , vol.18 , pp. 355
    • Liu, Y.-J.1    Oldneld, S.2    MacLennan, I.C.M.3
  • 61
    • 0026845876 scopus 로고
    • Maturation and dispersal of B cell clones during T cell-dependent antibody responses
    • MacLennan ICM, Liu Y-J, Johnson GD: Maturation and dispersal of B cell clones during T cell-dependent antibody responses. Immunol Rev 126:143, 1992
    • (1992) Immunol Rev , vol.126 , pp. 143
    • MacLennan, I.C.M.1    Liu, Y.-J.2    Johnson, G.D.3
  • 64
    • 0022244199 scopus 로고
    • The human gut contains a novel population of B lymphocytes which resemble marginal zone cells
    • Spencer J, Finn T, Pulford KA, Mason DY, Isaacson G: The human gut contains a novel population of B lymphocytes which resemble marginal zone cells. Clin Exp Immunol 62:607, 1985
    • (1985) Clin Exp Immunol , vol.62 , pp. 607
    • Spencer, J.1    Finn, T.2    Pulford, K.A.3    Mason, D.Y.4    Isaacson, G.5
  • 65
    • 0028051751 scopus 로고
    • Heterogeneity of M-cell-associated B and T cells in the human Peyer's patches
    • Farstad IN, Halstensen TS, Fausa O, Brandtzaeg P: Heterogeneity of M-cell-associated B and T cells in the human Peyer's patches. Immunology 83:457, 1994
    • (1994) Immunology , vol.83 , pp. 457
    • Farstad, I.N.1    Halstensen, T.S.2    Fausa, O.3    Brandtzaeg, P.4
  • 68
    • 0019876739 scopus 로고
    • Die Milz, ein überflüssiges Organ?
    • Pabst R: Die Milz, ein überflüssiges Organ? Med Klin 76:210, 1981
    • (1981) Med Klin , vol.76 , pp. 210
    • Pabst, R.1
  • 70
    • 0029971182 scopus 로고    scopus 로고
    • Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specific B cell activation
    • Toellner K-M, Gulbranson-Judge A, Taylor DR, Man-Yuen Sze D, MacLennan ICM: Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specific B cell activation. J Exp Med 183:2303, 1996
    • (1996) J Exp Med , vol.183 , pp. 2303
    • Toellner, K.-M.1    Gulbranson-Judge, A.2    Taylor, D.R.3    Man-Yuen Sze, D.4    MacLennan, I.C.M.5
  • 71
    • 0029328401 scopus 로고
    • Burkitt's lymphoma is a malignancy of mature B cells expressing somatically mutated V region genes
    • Klein U, Klein G, Ehlin-Henrikson B, Rajewsky K, Küppers R: Burkitt's lymphoma is a malignancy of mature B cells expressing somatically mutated V region genes. Mol Med 1:495, 1995
    • (1995) Mol Med , vol.1 , pp. 495
    • Klein, U.1    Klein, G.2    Ehlin-Henrikson, B.3    Rajewsky, K.4    Küppers, R.5
  • 74
    • 0030062645 scopus 로고    scopus 로고
    • Sequence analysis of immunoglobulin variable region genes that encode autoantibodies expressed by lymphomas of mucosa associated lymphoid tissue
    • Chapman CJ, Dunn-Walters DK, Stevenson FK, Hussel T, Isaacson PG, Spencer J: Sequence analysis of immunoglobulin variable region genes that encode autoantibodies expressed by lymphomas of mucosa associated lymphoid tissue. J Clin Pathol; Mol Pathol 49:M29, 1996
    • (1996) J Clin Pathol; Mol Pathol , vol.49
    • Chapman, C.J.1    Dunn-Walters, D.K.2    Stevenson, F.K.3    Hussel, T.4    Isaacson, P.G.5    Spencer, J.6
  • 75
    • 0029813167 scopus 로고    scopus 로고
    • Molecular Ig gene analysis reveals that monocytoid B cell lymphoma is a malignancy of mature B cells carrying somatically mutated V region genes and suggests that rearrangement of the kappa-deleting element (resulting in deletion of the Ig Kappa enhancers) abolishes somatic hypermutation in the human
    • Küppers R, Hajadi M, Plank L, Rajewsky K, Hansmann M-L: Molecular Ig gene analysis reveals that monocytoid B cell lymphoma is a malignancy of mature B cells carrying somatically mutated V region genes and suggests that rearrangement of the kappa-deleting element (resulting in deletion of the Ig Kappa enhancers) abolishes somatic hypermutation in the human. Eur J Immunol 26:1794, 1996
    • (1996) Eur J Immunol , vol.26 , pp. 1794
    • Küppers, R.1    Hajadi, M.2    Plank, L.3    Rajewsky, K.4    Hansmann, M.-L.5
  • 76
    • 0028820580 scopus 로고
    • H4 Ig gene family by diffuse large-cell lymphoma
    • H4 Ig gene family by diffuse large-cell lymphoma. Blood 86:3072, 1995
    • (1995) Blood , vol.86 , pp. 3072
    • Hsu, F.J.1    Levy, R.2
  • 77
    • 0021983455 scopus 로고
    • Immature sinus histiocytosis. Light- and electron-microscopic features, immunologic phenotype and relationship with marginal zone lymphocytes
    • Van den Oord JJ, De Wolf-Peters C, De Vos R, Desmet VJ: Immature sinus histiocytosis. Light-and electron-microscopic features, immunologic phenotype and relationship with marginal zone lymphocytes. Am J Pathol 118:266, 1985
    • (1985) Am J Pathol , vol.118 , pp. 266
    • Van Den Oord, J.J.1    De Wolf-Peters, C.2    De Vos, R.3    Desmet, V.J.4


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