Dual enigma of somatic hypermutation of immunoglobulin variable genes: Targeting and mechanism

Immunological Reviews

Volumn 162, Issue , 1998, Pages 89-96

  Winter, David B ^a   Gearhart, Patricia J ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DOUBLE STRANDED DNA;

ALLELE; CELL NUCLEUS MATRIX; DNA FLANKING REGION; DNA SEQUENCE; DNA STRAND BREAKAGE; EVOLUTION; EXON; GENE LOCUS; GENE MUTATION; GENE REARRANGEMENT; GENE TARGETING; GENETIC RECOMBINATION; GENETIC SELECTION; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; INTRON; MEIOSIS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REVIEW; SOMATIC MUTATION; SPONTANEOUS MUTATION; TRANSCRIPTION INITIATION;

ANIMALS; ANTIBODY DIVERSITY; GENE TARGETING; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; INTRONS; MEIOSIS; MUTATION; PROMOTER REGIONS (GENETICS); TRANSGENES;

EID: 0031920676     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-065X.1998.tb01432.x     Document Type: Review

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