In vitro high throughput screening of compounds for favorable metabolic properties in drug discovery

Combinatorial Chemistry and High Throughput Screening

Volumn 4, Issue 3, 2001, Pages 245-263

  Masimirembwa, Collen M ^a   Thompson, Richard ^a   Andersson, Tommy B ^a  

^a ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; CYTOCHROME P450; DRUG METABOLIZING ENZYME; ERYTHROMYCIN; ITRACONAZOLE; MIDAZOLAM; NEW DRUG; ORAL CONTRACEPTIVE AGENT; PRAZIQUANTEL; QUINIDINE; TAMOXIFEN; TERFENADINE; TOLBUTAMIDE; TRIAZOLAM; WARFARIN;

DNA MICROARRAY; DRUG ABSORPTION; DRUG CLEARANCE; DRUG DISPOSITION; DRUG HALF LIFE; DRUG METABOLISM; DRUG RESEARCH; DRUG SCREENING; DRUG TRANSFORMATION; ENZYME ACTIVITY; ENZYME INHIBITION; FLUORESCENCE; HUMAN; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; LIVER CELL; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; RADIOMETRY; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW;

EID: 0035031472     PISSN: 13862073     EISSN: None     Source Type: Journal    
DOI: 10.2174/1386207013331101     Document Type: Review

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