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Volumn 29, Issue 3, 1999, Pages 269-279

A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro

Author keywords

[No Author keywords available]

Indexed keywords

16ALPHA CYANOPREGNENOLONE; ALKALINE PHOSPHATASE PLACENTA ISOENZYME; CARBAMAZEPINE; CLOTRIMAZOLE; CYTOCHROME P450; DEXAMETHASONE; ERYTHROMYCIN; GLUCOCORTICOID RECEPTOR; METYRAPONE; MIFEPRISTONE; PHENOBARBITAL; PHENYLBUTAZONE; PHENYTOIN; RIFAMPICIN; SULFINPYRAZONE; TROLEANDOMYCIN; XENOBIOTIC AGENT;

EID: 0033000991     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/004982599238669     Document Type: Article
Times cited : (78)

References (44)
  • 1
    • 0018718742 scopus 로고
    • Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line
    • ADEN, D. P., FOGEL, A., PLOTKIN, S., DAMJANOV, I. and KNOWLES, B. B., 1979, Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line. Nature, 282, 615-616.
    • (1979) Nature , vol.282 , pp. 615-616
    • Aden, D.P.1    Fogel, A.2    Plotkin, S.3    Damjanov, I.4    Knowles, B.B.5
  • 3
    • 0029992789 scopus 로고    scopus 로고
    • Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes
    • BARWICK, J., QUATTROCHI, L., MILLS, A. S., POTENZA, C., TUKEY, R. H. and GUZELIAN, P. S., 1996, Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes. Molecular Pharmacology, 50, 10-16.
    • (1996) Molecular Pharmacology , vol.50 , pp. 10-16
    • Barwick, J.1    Quattrochi, L.2    Mills, A.S.3    Potenza, C.4    Tukey, R.H.5    Guzelian, P.S.6
  • 4
    • 0024545638 scopus 로고
    • Gene regulation by steroid hormones
    • BEATO, M., 1989, Gene regulation by steroid hormones. Cell, 56, 335-344.
    • (1989) Cell , vol.56 , pp. 335-344
    • Beato, M.1
  • 5
    • 0026520777 scopus 로고
    • Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16α-carbonitrile: Analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes
    • BURGER, H.-J., SCHUETZ, J. D., SCHUETZ, E. G. and GUZELIAN, P. S., 1992, Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16α-carbonitrile: analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes. Proceedings of the National Academy of Sciences, USA, 89, 2145-2149.
    • (1992) Proceedings of the National Academy of Sciences, USA , vol.89 , pp. 2145-2149
    • Burger, H.-J.1    Schuetz, J.D.2    Schuetz, E.G.3    Guzelian, P.S.4
  • 6
    • 0000326727 scopus 로고    scopus 로고
    • Drug discovery and drug metabolism
    • CASHMAN, J. R., 1996, Drug discovery and drug metabolism. Drug Discovery Today, 1, 209-216.
    • (1996) Drug Discovery Today , vol.1 , pp. 209-216
    • Cashman, J.R.1
  • 7
    • 0026496950 scopus 로고
    • The role of individual human cytochromes P450 in drug metabolism and clinical response
    • CHOLERTON, S., DALY, A. K. and IDLE, J. R., 1992, The role of individual human cytochromes P450 in drug metabolism and clinical response. TIPS, 13, 434-439.
    • (1992) TIPS , vol.13 , pp. 434-439
    • Cholerton, S.1    Daly, A.K.2    Idle, J.R.3
  • 9
    • 0023913120 scopus 로고
    • The steroid and thyroid hormone receptor superfamily
    • EVANS, R. M., 1988, The steroid and thyroid hormone receptor superfamily. Science, 240, 889-895.
    • (1988) Science , vol.240 , pp. 889-895
    • Evans, R.M.1
  • 10
    • 0026011273 scopus 로고
    • Protein binding of cortisol by means of competitive adsorption: Application to cortisol binding by serum of sixteen eutherian mammals
    • FENSKE, M., 1991, Protein binding of cortisol by means of competitive adsorption: application to cortisol binding by serum of sixteen eutherian mammals. Comparative Biochemistry and Physiology, 98, 61-66.
    • (1991) Comparative Biochemistry and Physiology , vol.98 , pp. 61-66
    • Fenske, M.1
  • 11
    • 0027348416 scopus 로고
    • Use of established hepatoma cell lines in biotoxicology
    • FERRO, M., BASSI, A. M., PENCO, S. and NANNI, G., 1993, Use of established hepatoma cell lines in biotoxicology. Cytotechnology, 11, S126-129.
    • (1993) Cytotechnology , vol.11
    • Ferro, M.1    Bassi, A.M.2    Penco, S.3    Nanni, G.4
  • 12
    • 0026753655 scopus 로고
    • Interleukin 6 down regulates the expression of transcripts encoding cytochrome P450 1A1, 1A2 and IIIA3 in human hepatoma cells
    • FUKUDA, Y., ISHIDA, N., NOGUCHI, T., KAPPAS, A. and SASSA, S., 1992, Interleukin 6 down regulates the expression of transcripts encoding cytochrome P450 1A1, 1A2 and IIIA3 in human hepatoma cells. Biochemical and Biophysical Research Communications, 184, 960-965.
    • (1992) Biochemical and Biophysical Research Communications , vol.184 , pp. 960-965
    • Fukuda, Y.1    Ishida, N.2    Noguchi, T.3    Kappas, A.4    Sassa, S.5
  • 14
    • 0025184340 scopus 로고
    • Mechanism-based inactivation of human liver microsomal cytochrome P-450 IIIA4 by gestodene
    • GUENGERICH, F. P., 1990, Mechanism-based inactivation of human liver microsomal cytochrome P-450 IIIA4 by gestodene. Chemical Research in Toxicology, 3, 363-371.
    • (1990) Chemical Research in Toxicology , vol.3 , pp. 363-371
    • Guengerich, F.P.1
  • 15
    • 0027137429 scopus 로고
    • Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers and its transcriptional control
    • HASHIMOTO, H., TOIDE, K., KITAMURA, R., FUJITA, M., TAGAWA, S., ITOH, S. and KAMATAKI, T., 1993, Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers and its transcriptional control. European Journal of Biochemistry, 218, 585-595.
    • (1993) European Journal of Biochemistry , vol.218 , pp. 585-595
    • Hashimoto, H.1    Toide, K.2    Kitamura, R.3    Fujita, M.4    Tagawa, S.5    Itoh, S.6    Kamataki, T.7
  • 16
    • 0024601325 scopus 로고
    • Co-induction of multiple hepatic cytochrome P-450 proteins and their mRNAs in rats treated with imidazole antimycotic agents
    • HOSTETLER, K. A., WRIGHTON, S. A., MOLOWA, D. T., THOMAS, P. E., LEVIN, W. and GUZELIAN, P. S., 1988, Co-induction of multiple hepatic cytochrome P-450 proteins and their mRNAs in rats treated with imidazole antimycotic agents. Molecular Pharmacology, 35, 279-285.
    • (1988) Molecular Pharmacology , vol.35 , pp. 279-285
    • Hostetler, K.A.1    Wrighton, S.A.2    Molowa, D.T.3    Thomas, P.E.4    Levin, W.5    Guzelian, P.S.6
  • 17
    • 0029906308 scopus 로고    scopus 로고
    • Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif
    • HUSS, J. M., WANG, S. I., ASTROM, A., McQUIDDY, P. and KASPER, C. B., 1996, Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif. Proceedings of the National Academy of Sciences, USA, 93, 4666-4670.
    • (1996) Proceedings of the National Academy of Sciences, USA , vol.93 , pp. 4666-4670
    • Huss, J.M.1    Wang, S.I.2    Astrom, A.3    McQuiddy, P.4    Kasper, C.B.5
  • 18
    • 0029991350 scopus 로고    scopus 로고
    • Transfecting mammalian cells: Optimization of critical parameters affecting calcium-phosphate precipitate formation
    • JORDAN, M., SCHALLHORN, A. and WURM F. M., 1996, Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formation. Nucleic Acids Research, 24, 596-601.
    • (1996) Nucleic Acids Research , vol.24 , pp. 596-601
    • Jordan, M.1    Schallhorn, A.2    Wurm, F.M.3
  • 25
    • 0024237552 scopus 로고
    • Cytochrome P-450 in human liver microsomes: High-performance liquid chromatographic isolation of three forms and their characterisation
    • KOMORI, M., HASHIZUME, T., OHI, H., MIURA, T., KITADA, M., NAGASHIMA, K. and KAMATAKI, T., 1988, Cytochrome P-450 in human liver microsomes: high-performance liquid chromatographic isolation of three forms and their characterisation. Journal of Biochemistry, 104, 912-916.
    • (1988) Journal of Biochemistry , vol.104 , pp. 912-916
    • Komori, M.1    Hashizume, T.2    Ohi, H.3    Miura, T.4    Kitada, M.5    Nagashima, K.6    Kamataki, T.7
  • 26
    • 0028608020 scopus 로고
    • Metabolism of cytochrome P450 3A substrates in vivo administered by the same route. Lack of correlation between alfentanil clearance and erythromycin breath test
    • KRIVORUK, Y., KINIRONS, M. T., WOOD, A. J. J. and WOOD, M., 1994, Metabolism of cytochrome P450 3A substrates in vivo administered by the same route. Lack of correlation between alfentanil clearance and erythromycin breath test. Clinical Pharmacology and Therapeutics, 56, 608-614.
    • (1994) Clinical Pharmacology and Therapeutics , vol.56 , pp. 608-614
    • Krivoruk, Y.1    Kinirons, M.T.2    Wood, A.J.J.3    Wood, M.4
  • 27
    • 0027946944 scopus 로고
    • The induction of five rat hepatic P450 Cytochromes by phenobarbital and similarly acting compounds is regulated by a sexually dimorphic, dietary-dependent endocrine factor that is highly strain specific
    • LARSEN, M. C., BRAKE, P. B., PARMAR, D. and JEFCOATE, C. R., 1994, The induction of five rat hepatic P450 Cytochromes by phenobarbital and similarly acting compounds is regulated by a sexually dimorphic, dietary-dependent endocrine factor that is highly strain specific. Archives of Biochemistry and Biophysics, 315, 24-34.
    • (1994) Archives of Biochemistry and Biophysics , vol.315 , pp. 24-34
    • Larsen, M.C.1    Brake, P.B.2    Parmar, D.3    Jefcoate, C.R.4
  • 30
    • 2642674399 scopus 로고    scopus 로고
    • Development of an in vitro reporter gene assay to assess xenobiotic induction of the human CYP3A4 gene
    • OGG, M. S., GRAY, T. J. B. and GIBSON, G. G., 1997, Development of an in vitro reporter gene assay to assess xenobiotic induction of the human CYP3A4 gene. European Journal of Drug Metabolism and Pharmacokinetics, 22, 311-313.
    • (1997) European Journal of Drug Metabolism and Pharmacokinetics , vol.22 , pp. 311-313
    • Ogg, M.S.1    Gray, T.J.B.2    Gibson, G.G.3
  • 31
  • 32
    • 0028789188 scopus 로고
    • A novel cis-acting element in a liver cytochrome P450 3A gene confers synergistic induction by glucocorticoids plus glucocorticoids
    • QUATTROCHI, L., MILLS, A. S., BARWICK, J. L., YOCKEY, C. B. and GUZELIAN, P. S., 1995, A novel cis-acting element in a liver cytochrome P450 3A gene confers synergistic induction by glucocorticoids plus glucocorticoids. Journal of Biological Chemistry, 270, 28917-28923.
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 28917-28923
    • Quattrochi, L.1    Mills, A.S.2    Barwick, J.L.3    Yockey, C.B.4    Guzelian, P.S.5
  • 33
    • 0027427551 scopus 로고
    • Regulation of human liver cytochromes P-450 in family 3A in primary and continuous culture of human hepatocytes
    • SCHUETZ, E. G., SCHUETZ, J. D., STROM, S. C., THOMPSON, M. T., FISHER, R. A., MOLOWA, D. T., LI, D. and GUZELIAN, P. S., 1993, Regulation of human liver cytochromes P-450 in family 3A in primary and continuous culture of human hepatocytes. Hepatology, 18, 1254-1262.
    • (1993) Hepatology , vol.18 , pp. 1254-1262
    • Schuetz, E.G.1    Schuetz, J.D.2    Strom, S.C.3    Thompson, M.T.4    Fisher, R.A.5    Molowa, D.T.6    Li, D.7    Guzelian, P.S.8
  • 34
    • 0028175687 scopus 로고
    • Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver
    • SCHUETZ, J. D., BEACH, D. L. and GUZELIAN, P. S., 1994, Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver. Pharmacogenetics, 4, 11-20.
    • (1994) Pharmacogenetics , vol.4 , pp. 11-20
    • Schuetz, J.D.1    Beach, D.L.2    Guzelian, P.S.3
  • 35
    • 0027180023 scopus 로고
    • Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta
    • SCHUETZ, J. D., KAUMA, S. and GUZELIAN, P. S., 1993, Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta. Journal of Clinical Investigation, 92, 1018-1024.
    • (1993) Journal of Clinical Investigation , vol.92 , pp. 1018-1024
    • Schuetz, J.D.1    Kauma, S.2    Guzelian, P.S.3
  • 36
    • 0030059885 scopus 로고    scopus 로고
    • Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells
    • SCHUETZ, J. D., SCHUETZ, E. G., THOTTASSERY, J. V., GUZELIAN, P. S., STROM, S. C. and SUN, D., 1996, Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells. Molecular Pharmacology, 49, 63-72.
    • (1996) Molecular Pharmacology , vol.49 , pp. 63-72
    • Schuetz, J.D.1    Schuetz, E.G.2    Thottassery, J.V.3    Guzelian, P.S.4    Strom, S.C.5    Sun, D.6
  • 37
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • SHIMADA, T., YAMAZAKI, H., MIMUA, M., INUI, Y. and GUENGERICH, F. P., 1994, Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. Journal of Pharmacology and Experimental Therapeutics, 270, 414-423.
    • (1994) Journal of Pharmacology and Experimental Therapeutics , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimua, M.3    Inui, Y.4    Guengerich, F.P.5
  • 40
    • 0023024338 scopus 로고
    • Macrolide antibiotics inhibit the degradation of the glucocorticoid-responsive cytochrome P-450p in rat hepatocytes in vivo and in primary monolayer culture
    • WATKINS, P. B., WRIGHTON, S. A., SCHUETZ, E. G., MAUREL, P. and GUZELIAN, P. S., 1986, Macrolide antibiotics inhibit the degradation of the glucocorticoid-responsive cytochrome P-450p in rat hepatocytes in vivo and in primary monolayer culture. Journal of Biological Chemistry, 261, 6264-6271.
    • (1986) Journal of Biological Chemistry , vol.261 , pp. 6264-6271
    • Watkins, P.B.1    Wrighton, S.A.2    Schuetz, E.G.3    Maurel, P.4    Guzelian, P.S.5
  • 41
    • 0013628806 scopus 로고    scopus 로고
    • Effect of endotoxins on transfection efficiency in eukaryotic cells
    • WEBER, M., MOLLER, K., WELZEK, M. and SCHORR, J., 1996, Effect of endotoxins on transfection efficiency in eukaryotic cells. Qiagen News, 4-5.
    • (1996) Qiagen News , pp. 4-5
    • Weber, M.1    Moller, K.2    Welzek, M.3    Schorr, J.4
  • 44
    • 0028307115 scopus 로고
    • Induction of the cytochrome P450 3A subfamily in rat liver correlates with the binding if inducers to a microsomal protein
    • WRIGHT, M. C. and PAINE, A. J., 1994, Induction of the cytochrome P450 3A subfamily in rat liver correlates with the binding if inducers to a microsomal protein. Biochemical and Biophysical Research Communications, 201, 973-979.
    • (1994) Biochemical and Biophysical Research Communications , vol.201 , pp. 973-979
    • Wright, M.C.1    Paine, A.J.2


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