Microfabricated centrifugal microfluidic systems: Characterization and multiple enzymatic assays

Analytical Chemistry

Volumn 71, Issue 20, 1999, Pages 4669-4678

  Duffy, David C ^a   Gillis, Heather L ^a   Lin, Joe ^a   Sheppard Jr , Norman F ^a   Kellogg, Gregory J ^a  

^a Gamera Bioscience   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLY(METHYL METHACRYLATE);

ANALYTIC METHOD; ARTICLE; CALORIMETRY; CENTRIFUGAL ANALYZER; CHEMICAL PARAMETERS; ENZYME ASSAY; ENZYME KINETICS; LIQUID; PHYSICAL PARAMETERS; PUMP;

EID: 0032746841     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac990682c     Document Type: Article

References (38)

1. Harrison, D. J., van den Berg, A., Eds. Micro Total Analysis Systems '98; Kluwer Academic Publishers: Dordrecht, 1998.
2. Manz, A., Becker, H., Eds. Microsystem Technology in Chemistry and Life Sciences; Springer-Verlag: Berlin, Germany, 1998.
3. Ramsey, J. M.; Jacobsen, S. C.; Knapp, M. R. Nature Med. 1995, 1, 1093-1096.
4. Kricka, L. J.; Wilding, P. Micromechanics and Nanotechnology. In Handbook of Clinical Automation, Robotics, and Optimization; Kost, G. J., Welsh, J., Eds; John Wiley and Sons: New York, 1996: pp 45-77.
5. Kovacs, G. T. A. Micromachined Transducers Sourcebook; WCB/McGraw-Hill: Boston, 1998.
6. Madou, M. Fundamentals of Microfabrication; CRC Press: Boca Raton, FL, 1997; pp 426-447.
7. For a review, see: Effenhauser, C. S.; Bruin, G. J. M.; Paulus, A. Electrophoresis 1997, 18, 2203-2213.
8. Grossman, P. D., Colburn, J. C., Eds. Capillary Electrophoresis: Theory and Practice; Academic Press: San Diego, 1992; pp 4-14.
9. Scott, C. S.; Burtis, C. A. Anal. Chem. 1973, 45, 327A-340A.
10. Scott, C. S.; Burtis, C. A. Centrifugal Analysis in Clinical Chemistry; Praeger: New York, 1980.
11. Schembri, C. T.; Ostoich, V.; Lingane, P. J.; Burd, T. L.; Buhl, S. N. Clin. Chem. 1992, 38, 1665-1670.
12. Schembri, C. T.; Burd, T. L.; Kopfsill, A. R.; Shea, L. R.; Braynin, B. J. Autom. Chem. 1995, 17, 99-104.
13. Madou, M.; Kellogg, G. J. Proc. SPIE 1998, 3259, 80-93.
14. Duffy, D. C.; McDonald, J. C.; Schueller, O. J. A.; Whitesides, G. M. Anal. Chem. 1998, 70, 4974-4984.
15. Lorenz, H.; Despont, M.; Fahrni, N.; Brugger, J.; Renaud, P.; Vettiger, P. Sens. Actuators A 1998, 64, 33-39.
16. Norman, R. A. Principles of Bioinstrumentation; Wiley: New York, 1988; pp 283-308.
17. Galambos, P.; Forster, F. K. in ref 1, pp 189-192.
18. Walker, J. R. Machining Fundamentals; Goodheart-Willcox Co.: South Holland, IL, 1993.
19. Renaud, P.; van Lintel, H.; Heuschkel, M.; Guérin, L. in ref 1, pp 17-22.
20. Paul, P. H.; Arnold, D. W.; Rakestraw, D. J., in ref 1, pp 49-52.
21. Chien, S.; Usami, S.; Skalak, R. In Handbook of Physiology; Renkin, E. M., Michel, C. C., Eds.; American Physiological Society: Bethesda, MD, 1984.
22. Wilding, P.; Pfahler, J.; Bau, H. H.; Zemel, J. N.; Kricka, L. J. Clin. Chem. 1994, 40, 43-47.
23. Fung, Y. C. Biomechanics, 2nd ed., Springer-Verlag: New York, 1993; pp 66-108.
24. The flow rates of DMSO were calculated using values of the viscosity and density taken from: CRC Handbook of Chemistry and Physics, 78th ed.; Lide, D. R., Ed; CRC Press: Boca Raton, FL, 1997.
25. Adamson, A. W.; Gast, A. P. Physical Chemistry of Surfaces, 6th ed.; Wiley: New York, 1997; pp 4-8.
26. We do not believe, however, that the use of these burst valves is limited to thicker channels: by using a photoresist that was optimized for thinner (10 μm) features, reproducible thicknesses and hence burst frequencies could be achieved.
27. For an example of high-throughput screening of inhibitors using enzymatic assays, see: Ambrose, W. P.; Semin, D. J.; Robbins, D. L.; Van Orden; Kashem; M. A.; Hamilton, S. A.; Nelson, R. M.; Jett, J. H.; Keller, R. A. Anal. Biochem. 1998, 263, 150-157.
28. Hadd, A. G.; Raymond, D. E.; Halliwell, J. W.; Jacobsen, S. C.; Ramsey, J. M. Anal. Chem. 1997, 69, 3407-3412.
29. Moser, I.; Jobst, G.; Svasek, P.; Varahram, M.; Urban, G. Sens. Actuators B 1997, 44, 377-380.
30. Harrison, D. J.; Fluri, K.; Chiem, N.; Tang, T.; Fan, Z. Sens. Actuators B 1996, 33, 105-109.
31. Koutny, L. B.; Schmalzing, D.; Taylor, T. A.; Fuchs, M. Anal. Chem. 1996, 68, 18-22.
32. Chiem, N.; Harrison, D. J. Anal. Chem. 1997, 69, 373-378.
33. Duffy, D. C.; Gillis, H. L.; Goldman, J.; Sheppard, N. F.; Kellogg, G. J., unpublished results, 1999.
34. Foulds, N. C.; Wilshere, J. M.; Green, M. J. Anal. Chim. Acta 1990, 229, 57-62.
35. Sáchez-Cabezudo, M.; Fernández-Romero, J. M.; Luque de Castro, M. D. Anal. Chim. Acta 1995, 308, 159-163.
36. Henderson, P. J. F. In Enzyme Assays: A Practical Approach; Eisenthal, R., Danson, M. J., Eds.; Oxford University Press: Oxford, U.K., 1995; Chapter 10, pp 277-316.
37. Foulds, N. C.; Frew, J. E.; Green, M. J. In Biosensors: A Practical Approach; Cass, A. E. G., Ed.; Oxford University Press: Oxford, U.K., 1990; Chapter 4, pp 97-124.
38. Persidis, A. Nature Biotechol. 1998, 16, 488-489.