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Volumn 26, Issue 2, 1998, Pages 85-90

Metabolic screening using on-line ultrafiltration mass spectrometry

Author keywords

[No Author keywords available]

Indexed keywords

10 HYDROXYIMIPRAMINE; 2 HYDROXYIMIPRAMINE; CHLORPROMAZINE; CYTOCHROME P450; DRUG METABOLITE; IMIPRAMINE; IMIPRAMINOXIDE; N DESMETHYLIMIPRAMINE; NARINGENIN; PENTOXYRESORUFIN; QUINIDINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCLASSIFIED DRUG;

EID: 0031913816     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (62)

References (18)
  • 1
    • 0000074870 scopus 로고    scopus 로고
    • Strategy and tactics in combinatorial organic synthesis: Application to drug discovery
    • Gordon EM, Gallop MA and Patel DV (1996) Strategy and tactics in combinatorial organic synthesis: application to drug discovery. Acc Chem Res 29:144-154.
    • (1996) Acc Chem Res , vol.29 , pp. 144-154
    • Gordon, E.M.1    Gallop, M.A.2    Patel, D.V.3
  • 2
    • 2842561522 scopus 로고    scopus 로고
    • Synthesis and applications of small molecule libraries
    • Thompson LA and Ellman JA (1996) Synthesis and applications of small molecule libraries. Chem Rev 29:132-143.
    • (1996) Chem Rev , vol.29 , pp. 132-143
    • Thompson, L.A.1    Ellman, J.A.2
  • 3
    • 0002974025 scopus 로고    scopus 로고
    • Mass spectrometry in the combinatorial chemistry revolution
    • Loo JA (1997) Mass spectrometry in the combinatorial chemistry revolution. Eur Mass Spectrom 3:93-104.
    • (1997) Eur Mass Spectrom , vol.3 , pp. 93-104
    • Loo, J.A.1
  • 4
    • 0030927388 scopus 로고    scopus 로고
    • Pulsed Ultrafiltration mass spectrometry: A new method for screening combinatorial libraries
    • van Breemen RB, Huang C-R, Nikolic D, Woodbury CP and Venton DL (1997) Pulsed Ultrafiltration mass spectrometry: A new method for screening combinatorial libraries. Anal Chem 69:2159-2164.
    • (1997) Anal Chem , vol.69 , pp. 2159-2164
    • Van Breemen, R.B.1    Huang, C.-R.2    Nikolic, D.3    Woodbury, C.P.4    Venton, D.L.5
  • 6
    • 0030022629 scopus 로고    scopus 로고
    • An overview of current cytochrome P450 technology for assessing the safety and efficacy of new materials
    • Parkinson A (1996) An overview of current cytochrome P450 technology for assessing the safety and efficacy of new materials. Toxicol Pathol 24:45-57.
    • (1996) Toxicol Pathol , vol.24 , pp. 45-57
    • Parkinson, A.1
  • 7
    • 0030588645 scopus 로고    scopus 로고
    • The use of adult human hepatocytes in primary culture and other in vitro systems to investigate drug metabolism in man
    • Maurel P (1996) The use of adult human hepatocytes in primary culture and other in vitro systems to investigate drug metabolism in man. Adv Drug Delivery Rev 22:105-132.
    • (1996) Adv Drug Delivery Rev , vol.22 , pp. 105-132
    • Maurel, P.1
  • 8
    • 0345540297 scopus 로고
    • Norepinephrine and the andrenergic receptors
    • Oxford University Press, New York
    • Nogrady T (1988) Norepinephrine and the andrenergic receptors. In Medicinal Chemistry: A Biochemical Approach, 2nd edition, p. 177, Oxford University Press, New York.
    • (1988) Medicinal Chemistry: A Biochemical Approach, 2nd Edition , pp. 177
    • Nogrady, T.1
  • 9
    • 0016157033 scopus 로고
    • Metabolism of tricyclic antidepressants
    • Gram LF (1974) Metabolism of tricyclic antidepressants. Dan Med Bull 21:218-231.
    • (1974) Dan Med Bull , vol.21 , pp. 218-231
    • Gram, L.F.1
  • 11
    • 0025733250 scopus 로고
    • Role of P450IID6, the target of the sparteine-debrisoquin oxidation polymorphism, in the metabolism of imipramine
    • Brosen K, Zeugin T and Meyer UA (1991) Role of P450IID6, the target of the sparteine-debrisoquin oxidation polymorphism, in the metabolism of imipramine. Clin Pharmacol Ther 49:609-617.
    • (1991) Clin Pharmacol Ther , vol.49 , pp. 609-617
    • Brosen, K.1    Zeugin, T.2    Meyer, U.A.3
  • 12
    • 0024260137 scopus 로고
    • Parallel pathway interactions in imipramine metabolism in rats
    • Chiba M, Fujita S and Suzuki T (1988) Parallel pathway interactions in imipramine metabolism in rats. J Pharm Sci 77:944-947.
    • (1988) J Pharm Sci , vol.77 , pp. 944-947
    • Chiba, M.1    Fujita, S.2    Suzuki, T.3
  • 13
    • 0028955961 scopus 로고
    • Brief comparison of the pharmacokinetics and pharmacodynamics of the traditional and newer antipsychotic drugs
    • DeVane CL (1995) Brief comparison of the pharmacokinetics and pharmacodynamics of the traditional and newer antipsychotic drugs. Am J Health Syst Pharm 52:S15-S18.
    • (1995) Am J Health Syst Pharm , vol.52
    • DeVane, C.L.1
  • 14
    • 0022357068 scopus 로고
    • Ethoxy-, pentoxy-, and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between different induced cytochromes P450
    • Burke MD, Thompson S, Elcombe CR, Halpert J, Haaparanta T and Mayer RT (1985) Ethoxy-, pentoxy-, and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P450. Biochem Pharmacol 34:3337-3347.
    • (1985) Biochem Pharmacol , vol.34 , pp. 3337-3347
    • Burke, M.D.1    Thompson, S.2    Elcombe, C.R.3    Halpert, J.4    Haaparanta, T.5    Mayer, R.T.6
  • 16
    • 0025685663 scopus 로고
    • In vitro inhibition of dihydropyridine oxidation and aflatoxin B1 activation in human liver microsomes by naringenin and other flavonoids
    • Guengerich FP and Kim DH (1990) In vitro inhibition of dihydropyridine oxidation and aflatoxin B1 activation in human liver microsomes by naringenin and other flavonoids. Carcinogenesis 11:2275-2279.
    • (1990) Carcinogenesis , vol.11 , pp. 2275-2279
    • Guengerich, F.P.1    Kim, D.H.2
  • 17
    • 0028828379 scopus 로고
    • High-performance liquid Chromatographic method for the analysis of imipramine metabolism in vitro by liver and brain microsomes
    • Sequeira DJ and HW Strobel (1995) High-performance liquid Chromatographic method for the analysis of imipramine metabolism in vitro by liver and brain microsomes. J Chromatogr B 673:251-258.
    • (1995) J Chromatogr B , vol.673 , pp. 251-258
    • Sequeira, D.J.1    Strobel, H.W.2
  • 18
    • 0029926747 scopus 로고    scopus 로고
    • Quinidine inhibits 7-hydroxylation of chlorpromazine in extensive metabolisers of debrisoquine
    • /accom
    • Muralidharan G, Cooper JK, Hawes EM, Korchincki ED and Midha KK (1996) Quinidine inhibits 7-hydroxylation of chlorpromazine in extensive metabolisers of debrisoquine. Eur J Clin Pharmacol 50:121-128. [/accom]
    • (1996) Eur J Clin Pharmacol , vol.50 , pp. 121-128
    • Muralidharan, G.1    Cooper, J.K.2    Hawes, E.M.3    Korchincki, E.D.4    Midha, K.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.