Prediction of hepatic clearance from microsomes, hepatocytes, and liver slices

Drug Metabolism Reviews

Volumn 29, Issue 4, 1997, Pages 891-922

  Brian Houston, J ^a   Carlile, David J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

6 CHLORO 4 CYCLOPROPYL 3,4 DIHYDRO 4 [(2 PYRIDYL)ETHYNYL] 2(1H) QUINAZOLINONE; ACENOCOUMAROL; BETA NAPHTHOFLAVONE; CAFFEINE; DEXAMETHASONE; DIAZEPAM; DOFETILIDE; ETHOXYCOUMARIN; ONDANSETRON; PHENOBARBITAL; PHENYTOIN; TACRINE; TOLBUTAMIDE; WARFARIN;

ANIMAL CELL; ANIMAL MODEL; CONFERENCE PAPER; DRUG CLEARANCE; DRUG METABOLISM; LIVER CELL; LIVER CLEARANCE; LIVER METABOLISM; LIVER MICROSOME; LIVER SLICE; MATHEMATICAL MODEL; NONHUMAN; RAT;

EID: 0344333422     PISSN: 03602532     EISSN: None     Source Type: Journal    
DOI: 10.3109/03602539709002237     Document Type: Conference Paper

References (30)

1. A. Rane, G. R. Wilkinson, and D. G. Shand, J. Pharmacol. Exp. Ther., 200, 420 (1977).
2. G. R. Wilkinson, Pharmacol. Rev., 39, 1 (1987).
3. J. B. Houston, Biochem. Pharmacol., 47, 1469 (1994).
4. J. R. Gillette, Ann. NY Acad. Sci., 179, 43 (1971).
5. G. R. Wilkinson and D. G. Shand, Clin. Pharmacol. Ther., 18, 377 (1975).
6. G. R. Wilkinson, in Pharmacokinetics in Risk Assessment, Drinking Water and Health, National Academy Press, Washington, DC, 1987, p. 80.
7. K. A. Hayes, B. S. Brennan, R. Chenery, and J. B. Houston, Drug Metab. Dispos., 23, 349 (1995).
8. E. I. L. Ashforth, D. J. Carlile, R. Chenery, and J. B. Houston, J. Pharmacol. Exp. Ther., 274, 761 (1995).
9. P. D. Worboys, A. Bradbury, and J. B. Houston, Xenobiotica, 26, 897 (1996).
10. L. G. M. Baars, M. T. Schepers, J. J. R. Hermans, H. J. J. Dahlmans, and H. H. W. Thijssen, J. Pharm. Pharmacol., 42, 861 (1990).
11. J. J. R. Hermans and H. H. W. Thijssen, Xenobiotica, 21, 295 (1991).
12. T. Prueksaritanont, S. K. Balani, L. M. Dwyer, J. D. Ellis, L. R. Kauffman, S. L. Varga, S. M. Pitzenberger, and A. D. Theoharides, Drug Metab. Dispos., 23, 688 (1995).
13. D. A. Smith, H. S. Rasmussen, D. A. Stopher, and D. K. Walker, Xenobiotica, 22, 709 (1992).
14. D. K. Walker, C. T. Alabaster, G. S. Congrave, M. B. Hargreaves, R. Hyland, B. C. Jones, L. J. Reed, and D. A. Smith, Drug Metabl. Dispos., 24, 447 (1996).
15. M. Kukan, Š. Bezek, W. F. Pool, and T. F. Woolf, Xenobiotica, 24, 1107 (1994).
16. K. Zomorodi, D. J. Carlile, and J. B. Houston, Xenobiotica, 25, 907 (1995).
17. D. J. Carlile, K. Zomorodi, and J. B. Houston, Drug Metab. Dispos. (1997) (in press).
18. D. J. Carlile, M. Dickins, and J. B. Houston, Br. J. Clin. Pharmacol., 38, 111 (1994).
19. J.-G. Joly, C. Doyon, and Y. Pesant, Drug Metab. Dispos., 3, 577 (1975).
20. R. Gebhardt, Pharmacol. Ther., 53, 275 (1992).
21. G. I. Murray and M. D. Burke, Biochem. Pharmacol., 50, 895 (1995).
22. M. Rowland, L. Z. Benet, and G. G. Graham, J. Pharmacokin. Biopharm., 1, 123 (1973).
23. K. S. Pang and M. Rowland, J. Pharmacokin. Biopharm., 5, 655 (1977).
24. M. S. Roberts and M. Rowland, J. Pharm. Sci., 74, 585 (1985).
25. R. Oliver, A. Jones, and M. Rowland, personal communication, 1996.
26. J. R. Gillette, in Pharmacokinetics. A Modern View (L. Z. Benet, G. Levy, and B. L. Ferrailo, eds.), Plenum Press, New York, 1984, pp. 235-252.
27. A. J. Stevens and J. B. Houston, in The Sixth Stowe Symposium on Drug Metabolism, Programme and Abstract booklet, 1996, p. 60.
28. S. E. Ball, V. E. Thiel, C. O. Tio, H.-K. Lim, J. Kao, S. Sisenwine, and J. Scatina, Drug Metab. Dispos., 24, 383 (1996).
29. P. D. Worboys, A. Bradbury, and J. B. Houston, Drug Metab. Dispos., 23, 393 (1995).
30. P. D. Worboys, A. Bradbury, and J. B. Houston, Drug Metab. Dispos., 24, 676 (1996).