Apoptosis and syncytial fusion in human placental trophoblast and skeletal muscle

International Review of Cytology

Volumn 205, Issue , 2001, Pages 215-253

  Huppertz, Berthold ^a   Tews, Dominique S ^b   Kaufmann, Peter ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Apoptosis; Differentiation; Myotube; Placenta; Skeletal muscle; Syncytial fusion; Trophoblast

Indexed keywords

APOPTOSIS; CELL FUSION; HUMAN; MYOTUBE; PLACENTA; PRIORITY JOURNAL; REVIEW; SKELETAL MUSCLE; SYNCYTIUM; TROPHOBLAST;

EID: 0035028511     PISSN: 00747696     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0074-7696(01)05005-7     Document Type: Article

References (225)

1. Monoclonal antiphosphatidylserine antibody inhibits intercellular fusion of the choriocarcinoma line, JAR
2. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
3. Myogenin expression, cell cycle withdrawal, and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis
4. Calpastatin-modulation of m-calpain activity is required for myoblast fusion
5. The role of calpastatin (the specific calpain inhibitor) in myoblast differentiation and fusion
6. Calpain and calpastatin in myoblast differentiation and fusion: Effects of inhibitors
7. The calpain-calpastatin system and protein degradation in fusing myoblasts
8. Regulatory mechanisms in maintenance and modulation of transmembrane lipid asymmetry: Pathophysiological implications
9. Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud
10. The nuclear matrix in pathology
11. Electron microscopic observations on the cytotrophoblast contribution to the syncytium in the human placenta
12. Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of beta-catenin
13. Human skeletal muscle cytosols are refractory to cytochrome c-dependent activation of type-II caspases and lack APAF-1
14. Interpretation of syncytial sprouts and bridges in the human placenta
15. Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis
16. Apaf-1 (CED-4 homolog) regulates programmed cell death in mammalian development
17. Fusion competence of myoblasts rendered genetically null for N-cadherin in culture
18. Transcriptional mechanisms regulating MyoD expression in the mouse
19. Shaping limbs by apoptosis
20. Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment
21. Caspases: The executioners of apoptosis
22. Transient involvement of gap junctional communication before fusion of newborn rat myoblasts
23. Lysosomes in human placenta
24. A possible role for placental lysosomes in the formation of villous syncytiotrophoblast
25. Single-cell analysis of regulatory gene expression in quiescent and activated mouse skeletal muscle satellite cells
26. Cell death via apoptosis and its relationship to growth, development and differentiation of both tumour and normal cells
27. Proteases to die for
28. Specific cleavage of alpha-fodrin during Fas- and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1 beta-converting enzyme/Ced-3 protease distinct from the poly(ADP-ribose) polymerase protease
29. Apoptosis of epithelial cells in vivo involves tissue transglutaminase upregulation
30. Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes
31. Lens fibre cell differentiation - A link with apoptosis?
32. Apoptosis and atrophy in rat slow skeletal muscles in chronic heart failure
33. Differential expression of G1 cyclins during human placentogenesis
34. 1 checkpoint control
35. Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis
36. IAP family proteins - Suppressors of apoptosis
37. Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases
38. Presence of double-strand breaks with single-base 3′ overhangs in cells undergoing apoptosis but not necrosis
39. Bcl-2 expression identifies an early stage of myogenesis and promotes clonal expansion of muscle cells
40. Myoblast fusion requires fibronectin degradation by exteriorized m-calpain
41. Potential m-calpain substrates during myoblast fusion
42. Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c
43. ARC inhibits cytochrome c release from mitochondria and protects against hypoxia-induced apoptosis in heartderived H9c2 cells
44. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
45. Effects of divalent cations on M-cadherin expression and distribution during primary rat myogenesis in vitro
46. Plasma membrane alterations and cytoskeletal changes in apoptosis
47. Clearance: The last and often forgotten stage of apoptosis
48. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
49. Bcl-2 regulates chondrocyte morphology and aggrecan gene expression independent of caspase activation and full apoptosis
50. Transglutaminase induction by various cell death and apoptosis pathways
51. Acute infantile spinal muscular atrophy. Muscle apoptosis as a proposed pathogenetic mechanism
52. The role of gap junctions in trophoblastic cell fusion in the guinea-pig placenta
53. INK4c and its predominant association with CDK4 and CDK6 during myogenic differentiation
54. A license to kill
55. Levels of hepatocyte growth factor and its messenger ribonucleic acid in uncomplicated pregnancies and those complicated by preeclampsia
56. Persistent expression of MNF identifies myogenic stem cells in postnatal muscles
57. Lamins and lamin-associated proteins
58. Caspases cleave focal adhesion kinase during apoptosis to generate a FRNK-like polypeptide
59. A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo
60. Cell deaths in normal vertebrate ontogeny
61. Bcl-2 family members and the mitochondria in apoptosis
62. Sequential and rapid activation of select caspases during apoptosis of normal intestinal epithelial cells
63. MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation
64. Gamma-sarcoglycan deficiency leads to muscle membrane defects and apoptosis independent of dystrophin
65. Differential requirement for caspase 9 in apoptotic pathways in vivo
66. Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD
67. Fas and Fas-ligand are expressed in the uteroplacental unit of first-trimester pregnancy
68. Analysis of the role of Bcl-2 in apoptosis
69. Cleavage of beta-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: Evidence for a role for caspases and metalloproteinases
70. The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation
71. Nonionic detergents induce dimerization among members of the Bcl-2 family
72. Bax in murline thymus is a soluble monomeric protein that displays differential detergent-induced conformations
73. Cytosol-to-membrane redistribution of bax and Bcl-xL during apoptosis
74. Role of calpain in skeletal-muscle protein degradation
75. Apoptosis-inducing members of the tumor necrosis factor supergene family: Potential functions in placentae - A review
76. ADAMs and cell fusion
77. Trophoblast apoptosis and placental development - A workshop report
78. Villous cytotrophoblast regulation of the syncytial apoptotic cascade in the human placenta
79. The apoptosis cascade - Orphological and immunohistochemical methods for its visualization
80. The apoptosis cascade progresses during turnover of human trophoblast: Analysis of villous cytotrophoblast and syncytial fragments in vitro
81. Oxygen modulates the balance between apoptosis and necrosis in human villous trophoblast
82. Trophoblastzellen im strömenden blut
83. A role for caspases in lens fiber differentiation
84. Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis
85. Syncytial knots and intervillous bridges in the human placenta: An ultrastructural study
86. Untersuchungen über die langhanszellen in der menschlichen placenta
87. Enzymhistochemische untersuchungen an reifen menschlichen placentazotten. I. Reifungs- und alterungsvorgänge am trophoblasten
88. Enzymhistochemische untersuchungen an reifen menschlichen placentazotten. II. Zur gliederung des syncytiotrophoblasten
89. Die ultrastruktur von langhanszellen in pathologischen menschlichen placenten
90. Die funktionelle bedeutung der langhanszellen der menschlichen placenta
91. Cleavage of actin by interleukin 1β-converting enzyme to reverse DNase I inhibition
92. An electron-microscope study of liver cell necrosis due to heliotrine
93. An electron microscopic study of liver cell necrosis due to albitocin
94. Shrinkage necrosis: A distinct mode of cellular death
95. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
96. Proteolytic activities that mediate apoptosis
97. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
98. The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
99. RNA synthesis and splicing interferes with DNA in situ end labeling techniques used to detect apoptosis
100. MyoD protein accumulates in satellite cells and is neurally regulated in regenerating myotubes and skeletal muscle fibers
101. Maternal anemia results in increased proliferation in human placental villi
102. ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases
103. Immunohistochemical analysis of McI-1 protein in human tissues. Differential regulation of McI-1 and Bcl-2 protein production suggests a unique role for McI-1 in control of programmed cell death in vivo
104. The mitochondrial death/life regulator in apoptosis and necrosis
105. Purification of a calcium-activated neutral proteinase from human placenta
106. Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution
107. Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcriptional arrest
108. Desmin-lacZ transgene expression and regeneration within skeletal muscle transplants
109. Deciphering the pathways of life and death
110. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
111. Apoptosis and atrophy in rat slow skeletal muscles in chronic heart failure
112. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
113. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kB activation prevents cell death
114. The ATP binding cassette transporter ABCl is required for the engulfment of corpses generated by apoptotic cell death
115. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
116. Modulation of phosphatidylserine epitope expression by Be Wo cells during forskolin treatment
117. Analysis of events associated with serum deprivation-induced apoptosis in C3H/So18 muscle satellite cells
118. The caspase-3 precursor has a cytosolic and mitochondrial distribution: Implications for apoptotic signaling
119. Recent advances on neuronal caspases in development and neurodegeneration
120. Activation of caspase-3 and apoptosis in cerebellar granule cells
121. Ultrastructural features of cellular maturation and aging in human trophoblast
122. Structural properties of the putative fusion peptide of fertillin, a protein active in sperm-egg fusion, upon interaction with the lipid bilayer
123. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Ab1
124. CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene
125. Satellite cells of skeletal muscle fibers
126. Proliferation, differentiation and apoptosis in villous trophoblast at 13-41 weeks of gestation (including observations on annulate lamellae and nuclear pore complexes)
127. Regulation of cell division cycle progression by bcl-2 expression: A potential mechanism for inhibition of programmed cell death
128. Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak
129. Multiple domains of DFF45 bind synergistically to DFF40: Roles of caspase cleavage and sequestration of activator domain of DFF40
130. Expression of G1 cyclins and cyclin-dependent kinase-2 activity during terminal differentiation of cultured human trophoblast
131. Is intercellular communication via gap junctions required for myoblast fusion?
132. Muscle apoptosis in humans occurs in normal and denervated muscle, but not in myotonic dystrophy, dystrophinopathies or inflammatory disease
133. Mitochondria and apoptosis
134. The role of the caspase family of cysteine proteases in apoptosis
135. Myogenic stem cells reside in a small subset of muscle cells that express Bcl-2 and are resistant to apoptosis
136. Seeking muscle stem cells
137. Laminin alpha 2 chain-null mutant mice by targeted disruption of the Lama2 gene: A new model of merosin (laminin 2)-deficient congenital muscular dystrophy
138. Defining the regulatory networks for muscle development
139. alpha-dystroglycan is a laminin receptor involved in extracellular matrix assembly on myotubes and muscle cell viability
140. The apoptotic and nonapoptotic nature of the terminal differentiation of erythroid cells
141. Transgenic mouse models of muscle aging
142. FLICE, a novel FADD-homologous ICE/CED-3-lyike protease, is recruited to the CD95 (Fas/APO-1) death - Inducing signaling complex
143. Apoptotic changes occur in syncytiotrophoblast of human placental villi where fibrin type fibrinoid is deposited at discontinuities in the villous trophoblast
144. Molecular cloning and characterization of two novel pro-apoptotic isoforms of caspase-10
145. Targeting of Bcl-2 to the mitochondrial outer membrane by a COOH-terminal signal anchor sequence
146. Evidence in the mouse for self-renewing stem cells in the formation of a segmented longitudinal structure, the myotome
147. Bcl-2 and Bax protein expression in human myopathies
148. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
149. Expression of a Bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo
150. Identification of mRNAs associated with programmed cell death in immature thymocytes
151. Fas activates NF-kB and induces apoptosis in T-cell lines by signaling pathways distinct from those induced by TNF-alpha
152. Apoptosis in rodent peri-implantation embryos: Differential susceptibility of inner cell mass and trophectoderm cell lineages - A review
153. Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex
154. Human tumour necrosis factor: Precursor structure, expression and homology to lymphotoxin
155. Lack of transglutaminase protein crosslinking leads to leakage of macromolecules from dying cells: Relationship to development of autoimmunity in MRL lpr/lpr mice
156. The CD95 (APO-1/Fas) receptor activates NF-kB independently of its cytotoxic function
157. Blocking gap junctional intercellular communication in myoblasts inhibits myogenin and MRF4 expression
158. Age-dependent changes in myogenic precursor cell compartment sizes. Evidence for the existence of a stem cell
159. Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein
160. Double identity for proteins of the Bcl-2 family
161. Macrophage-induced apoptosis of extravillous trophoblast cells limits endovascular trophoblast invasion in pre-eclampsia - In vivo findings and in vitro evidence
162. Studies of human placental morphogenesis. I. Radioautographic studies of human placenta utilizing tritiated thymidine
163. Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c
164. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
165. Implication of calpain in caspase activation during B cell clonal deletion
166. Expression of Fas ligand by human cytotrophoblasts: Implications in placentation and fetal survival
167. Differentiation-dependent expression of the Bcl-2 proto-oncogene in the human trophoblast lineage
168. Detection of pro-caspase-3 in cytosol and mitochondria of various tissues
169. Apoptosis of skeletal muscles during development and disease
170. Apoptotic myonuclei in human Duchenne muscular dystrophy
171. Morphologic criteria and detection of apoptosis
172. Phagocytic docking without shocking
173. Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis
174. Skeletal muscle satellite cells: Changes in proliferation potential as a function of age
175. Skeletal muscle satellite cells
176. Multiple Bcl-2 family members demonstrate selective dimerizations with Bax
177. A low-calcium-requiring calcium-activated neutral proteinase from human placenta
178. Serial killers: Ordering caspase activation events in apoptosis
179. Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
180. A unique pattern of expression of the four muscle regulatory factors distinguishes somitic from embryonic, fetal, and newborn mouse myogenic cells
181. Somite subdomains, muscle cell origins, and the four muscle regulatory factor proteins
182. The effects of aging on satellite cells in skeletal muscles of mice and rats
183. Ontogeny of hepatocyte growth factor (HGF) and its receptor (c-met) in human placenta: Reduced HGF expression in intrauterine growth restriction
184. Identification of placental cytokine-producing cells in term and preterm labor
185. Cleavage of lamin A by Mch2α but not CPP32: Multiple ICE-related proteases with distinct substrate recognition properties are active in apoptosis
186. 2+-dependent endonuclease of bull seminal plasma induced by ADP-ribosylation
187. HGF/SF is present in normal adult skeletal muscle and is capable of activating satellite cells
188. Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
189. DNA fragmentation and bcl-2 expression in infantile spinal muscular atrophy
190. Apoptosis-related proteins in skeletal muscle fibers of spinal muscular atrophy
191. DNA-fragmentation and expression of apoptosis-related proteins in muscular dystrophies
192. DNA-fragmentation and apoptosis-related proteins of muscle cells in motor neuron disorders
193. DNA-fragmentation and expression of apoptosis-related proteins in experimentally denervated and reinnervated rat facial muscle
194. Monoclonal antibody-mediated tumor regression by induction of apoptosis
195. Trophoblasts express Fas ligand: A proposed mechanism for immune privilege in placenta and maternal invasion
196. Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor
197. Bcl-xL is a negative regulator of caspase-3 activation in immature neurons during development
198. Merosin and laminin in myogenesis; specific requirement for merosin in myotube stability and survival
199. 1) in muscle function and survival. Disrupted expression in merosin-deficient congenital muscular dystrophy
200. Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival
201. Caspases and caspase inhibitors
202. Antiphosphatidylserine antibody removes annexin-V and facilitates the binding of prothrombin at the surface of a choriocarcinoma model of trophoblast differentiation
203. Cell cycle exit upon myogenic differentiation
204. Rb functions to inhibit apoptosis during myocyte differentiation
205. Calpain activation is upstream of caspases in radiation-induced apoptosis
206. Accelerated age-related decline in replicative life-span of Duchenne muscular dystrophy myoblasts: Implications for cell and gene therapy
207. Caspase activation in the terminal differentiation of human epidermal keratinocytes
208. Cleavage of focal adhesion kinase by caspases during apoptosis
209. Back and forth: The regulation and function of transbilayer phospholipid movement in eukaryotic cells
210. Membrane events involved in fusion of uterine epithelial cells in pseudopregnant rabbits
211. Caspase-dependent activation of calpain during drug-induced apoptosis
212. Members of the Bcl-2 and caspase families regulate nuclear degeneration during chick lens fibre differentiation
213. A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor
214. Cell heterogeneity upon myogenic differentiation: Down-regulation of MyoD and Myf-5 generates "reserve cell"
215. Transducing signals of life and death
216. Cytotoxicity of tumor necrosis factor-alpha and gamma-interferon against primary human placental trophoblasts
217. Expression of the human p55 and p75 tumor necrosis factor receptors in primary villous trophoblasts and their role in cytotoxic signal transduction
218. Skeletal muscle determination and differentiation: Story of a core regulatory network and its context
219. Involvement of M-cadherin in terminal differentiation of skeletal muscle cells
220. Multiple proteases are involved in thymocyte apoptosis
221. Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions
222. Demonstration of the expression of CD95 ligand transcript and protein in human placenta
223. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
224. An APAF-1-cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9