Fusion competence of myoblasts rendered genetically null for N-cadherin in culture

Journal of Cell Biology

Volumn 138, Issue 2, 1997, Pages 331-336

  Charlton, Carol A ^a   Mohler, William A ^a,c   Radice, Glenn L ^b,d   Hynes, Richard O ^b   Blau, Helen M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CADHERIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ADHESION; CELL AGGREGATION; CELL FUSION; MALE; MOUSE; MUSCLE DEVELOPMENT; MYOBLAST; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CADHERINS; CELL FUSION; CELLS, CULTURED; CLONE CELLS; FIBROBLAST GROWTH FACTOR 2; HOMOZYGOTE; MICE; MICE, NUDE; MUSCLE FIBERS; MUSCLE, SKELETAL; MUTATION;

ANIMALIA;

EID: 0030820050     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.138.2.331     Document Type: Article

References (40)

1. 2(+)-dependent intercellular adhesion in bovine aortic and human umbilical vein endothelial cells by heparin-binding growth factors. J. Cell. Physiol. 143:39-51.
2. Blau, H.M., C.-P. Chiu, and C. Webster. 1983. Cytoplasmic activation of human nuclear genes in stable heterokaryons. Cell. 32:1171-1180.
3. Brand-Saberi, B., A.J. Gamel, V. Krenn, T.S. Muller, J. Wilting, and B. Christ. 1996. N-cadherin is involved in myoblast migration and muscle differentiation in the avian limb bud. Dev. Biol. 178:160-173.
4. Braun, T., M.A. Rudnicki, H.H. Arnold, and R. Jacnisch. 1992. Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death. Cell. 71:369-382.
5. Cremer, H., R. Lange, A. Christoph, M. Plomann, G. Vopper, J. Roes, R. Brown, S. Baldwin, P. Kraemer, S. Scheff, et al. 1994. Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning. Nature (Lond.). 367:455-459.
6. Diaz-Gonzalez, F., J. Forsyth, B. Steiner, and M.H. Ginsberg. 1996. Transdominant inhibition of integrin function. Mol. Biol. Cell. 7:1939-1951.
7. Dickson, G., D. Peck, S.E. Moore, C.H. Barton, and F.S. Walsh. 1990. Enhanced myogenesis in NCAM-transfected mouse myoblasts. Nature (Lond.). 344:348-351.
8. Duband, J.L., S. Dufour, K. Hatta, M. Takeichi, G.M. Edelman, and J.P. Thiery. 1987. Adhesion molecules during somitogenesis in the avian embryo. J. Cell Biol. 104:1361-1374.
9. Fassler, R., and M. Meyer. 1995. Consequences of lack of β1 integrin gene expression in mice. Genes Dev. 9:1896-1908.
10. Fredette, B., U. Rutishauser, and L. Landmesser. 1993. Regulation and activity-dependence of N-cadherin, NCAM isoforms, and polysialic acid on chick myotubes during development. J. Cell Biol. 123:1867-1888.
11. Geiger, B., and O. Ayalon. 1992. Cadherins. Annu. Rev. Cell Biol. 8:307-332.
12. Gumbiner, B.M. 1996. Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell. 84:345-357.
13. Hasty, P., A. Bradley, J.H. Morris, D.G. Edmondson, J.M. Venuti, E.N. Olson, and W.H. Klein. 1993. Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene. Nature (Lond.). 364:501-506.
14. Hatta, K., S. Takagi, H. Fujisawa, and M. Takeichi. 1987. Spatial and temporal expression pattern of N-cadherin cell adhesion molecules correlated with morphogenetic processes of chicken embryos. Dev. Biol. 120: 215-227.
15. Holt, C.E., P. Lemaire, and J.B. Gurdon. 1994. Cadherin-mediated cell interactions are necessary for the activation of MyoD in Xenopus mesoderm. Proc. Natl. Acad. Sci. USA. 91:10844-10848.
16. Hynes, R.O. 1996. Targeted mutations in cell adhesion genes: what have we learned from them? Dev. Biol. 180:402-412.
17. Knudsen, K.A., S.A. McElwee, and L. Myers. 1990. A role for the neural cell adhesion molecule, NCAM, in myoblast interaction during myogenesis. Dev. Biol. 138:159-168.
18. 2(+)-dependent adhesion molecule. N-cadherin, in myoblast interaction during myogenesis. Exp. Cell Res. 188:175-184.
19. MacCalman, C.D., N. Bardeesy, P.C. Holland, and O.W. Blaschuk. 1992. Noncoordinate developmental regulation of N-cadherin. N-CAM, integrin, and fibronectin mRNA levels during myoblast terminal differentiation. Dev. Dyn. 195:127-132.
20. Matsunami, H., and M. Takeichi. 1995. Fetal brain subdivisions defined by R- and E-cadherin expressions: evidence for the role of cadherin activity in region-specific, cell-cell adhesion. Dev. Biol. 172:466-478.
21. McDonald, K.A., A.F. Horwitz, and K.A. Knudsen. 1995. Adhesion molecules and skeletal myogenesis. Semin. Dev. Biol. 6:105-116.
22. Mege, R.M., D. Goudou, C. Diaz, M. Nicolet, L. Garcia, G. Geraud, and F. Rieger. 1992. N-cadherin and N-CAM in myoblast fusion: compared localisation and effect of blockade by peptides and antibodies. J. Cell Sci. 103:897-906.
23. Menko, A.S., and D. Boettiger. 1987. Occupation of the extracellular matrix receptor, integrin, is a control point for myogenic differentiation. Cell. 51:51-57.
24. Meyer, R.A., D.W. Laird, J.P. Revel, and R.G. Johnson. 1992. Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies. J. Cell Biol. 119:179-189.
25. Mohler, W.A., and H.M. Blau. 1996. Gene expression and cell fusion analyzed by lacZ complementation in mammalian cells. Proc. Natl. Acad. Sci. USA. 93:12423-12427.
26. Mortensen, R.M., D.A. Conner, S. Chao, A.A. Geisterfer-Lowrance, and J.G. Seidman. 1992. Production of homozygous mutant ES cells with a single targeting construct. Mol. Cell Biol. 12:2391-2395.
27. Nabeshima, Y., K. Hanaoka, M. Hayasaka, E. Esumi, S. Li, I. Nonaka, and Y. Nabeshima. 1993. Myogenin gene disruption results in perinatal lethality because of severe muscle defect. Nature (Lond.). 364:532-535.
28. Nolan, G.P., S. Fiering, J.F. Nicolas, and L.A. Herzenberg. 1988. Fluorescence-activated cell analysis and sorting of viable mammalian cells based on β-D-galactosidase activity after transduction of Escherichia coli lacZ. Proc. Natl. Acad. Sci. USA. 85:2603-2607.
29. Partridge, T.A., J.E. Morgan, G.R. Coulton, E.P. Hoffman, and L.M. Kunkel. 1989. Conversion of mdx myofibres from dystrophin-negative to -positive by injection of normal myoblasts. Nature (Lond.) 337:176-179.
30. Radice, G.L., H. Rayburn, H. Matsunami, K.A. Knudsen, M. Takeichi, and R.O. Hynes. 1997. Developmental defects in mouse embryos lacking N-cadherin. Dev. Biol. 181:64-78.
31. Rando, T.A., and H.M. Blau. 1994. Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy. J. Cell Biol. 125:1275-1287.
32. Rosen, G.D., J.R. Sanes, R. LaChance, J.M. Cunningham, J. Roman, and D.C. Dean. 1992. Roles for the integrin VLA-4 and its counter receptor VCAM-1 in myogenesis. Cell. 69:1107-1119.
33. Rudnicki, M.A., T. Braun, S. Hinuma, and R. Jaenisch. 1992. Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development. Cell. 71:383-390.
34. Schachner, M. 1993. The analysis of neural recognition molecules: benefits and vicissitudes of functional knock-outs using antibodies and gene ablation. Curr. Opin. Cell Biol. 5:786-790.
35. Takeichi, M. 1991. Cadherin cell adhesion receptors as a morphogenetic regulator. Science (Wash. DC). 251:1451-1455.
36. Williams, E.J., J. Furness, F.S. Walsh, and P. Doherty. 1994. Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin. Neuron. 13:583-594.
37. Williams, E.J., J. Furness, F.S. Walsh, and P. Doherty. 1994. Characterisation of the second messenger pathway underlying neurite outgrowth stimulated by FGF. Development. 120:1685-1693.
38. Yagami-Hiromasa, T., T. Sato, T. Kurisaki, K. Kamijo, Y. Nabeshima, and A. Fujisawa-Sehara. 1995. A metalloprotease-disintegrin participating in myoblast fusion. Nature (Lond.). 377:652-656.
39. Yang, J.T., T.A. Rando, W.A. Mohler, H. Rayburn, H.M. Blau, and R.O. Hynes. 1996. Genetic analysis of α-4 integrin functions in the development of mouse skeletal muscle. J. Cell Biol. 135:829-835.
40. Zeschnigk, M., D. Kozian, C. Kuch, M. Schmoll, and A. Starzinski-Powtz. 1995. Involvement of M-cadherin in terminal differentiation of skeletal muscle cells. J. Cell Sci. 108:2973-2981.