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Volumn 9, Issue 6, 1998, Pages 1589-1601

Cleavage of β-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: Evidence for a role for caspases and metalloproteinases

Author keywords

[No Author keywords available]

Indexed keywords

CADHERIN; CATENIN; METALLOPROTEIN; PLAKOGLOBIN;

EID: 0031867833     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.9.6.1589     Document Type: Article
Times cited : (237)

References (59)
  • 1
    • 0028578064 scopus 로고
    • Assembly of the cadherin-catenin complex in vitro with recombinant proteins
    • Aberle, H., Butz, S., Stappert, J., Weissig, H., Kemler, R., and Hoschuetzky, H. (1994). Assembly of the cadherin-catenin complex in vitro with recombinant proteins. J. Cell Sci. 107, 3655-3663.
    • (1994) J. Cell Sci. , vol.107 , pp. 3655-3663
    • Aberle, H.1    Butz, S.2    Stappert, J.3    Weissig, H.4    Kemler, R.5    Hoschuetzky, H.6
  • 2
    • 0030061120 scopus 로고    scopus 로고
    • Single amino acid substitutions in proteins of the armadillo gene family abolish their binding to α-catenin
    • Aberle, H., Schwartz, H., Hoschuetzky, H., and Kemler R. (1996). Single amino acid substitutions in proteins of the armadillo gene family abolish their binding to α-catenin. J. Biol. Chem. 271, 1520-1526.
    • (1996) J. Biol. Chem. , vol.271 , pp. 1520-1526
    • Aberle, H.1    Schwartz, H.2    Hoschuetzky, H.3    Kemler, R.4
  • 3
    • 0030836799 scopus 로고    scopus 로고
    • Cellular redistribution of protein tyrosine phosphatases LAR and PTPsigma by inducible proteolytic processing
    • Aicher, B., Lerch, M.M, Muller, T., Schilling, J., and Ullrich, A. (1997). Cellular redistribution of protein tyrosine phosphatases LAR and PTPsigma by inducible proteolytic processing. J. Cell Biol. 138, 681-696.
    • (1997) J. Cell Biol. , vol.138 , pp. 681-696
    • Aicher, B.1    Lerch, M.M.2    Muller, T.3    Schilling, J.4    Ullrich, A.5
  • 4
    • 0030872246 scopus 로고    scopus 로고
    • Endothelial-dependent mechanisms regulate leukocyte transmigration: A process involving the proteasome and disruption of the vascular endothelial-cadherin complex at endothelial cell-to-cell junctions
    • Allport, J.R., Ding, H., Collins, T., Gerritsen, M.E., and Luscinskas, F.W. (1997). Endothelial-dependent mechanisms regulate leukocyte transmigration: a process involving the proteasome and disruption of the vascular endothelial-cadherin complex at endothelial cell-to-cell junctions. J. Exp. Med. 186, 517-527.
    • (1997) J. Exp. Med. , vol.186 , pp. 517-527
    • Allport, J.R.1    Ding, H.2    Collins, T.3    Gerritsen, M.E.4    Luscinskas, F.W.5
  • 5
    • 0031044652 scopus 로고    scopus 로고
    • Mammalian cell death proteases: A family of highly conserved aspartate specific cysteine proteases
    • Alnemri, E.S. (1997). Mammalian cell death proteases: a family of highly conserved aspartate specific cysteine proteases. J. Cell. Biochem. 64, 33-42.
    • (1997) J. Cell. Biochem. , vol.64 , pp. 33-42
    • Alnemri, E.S.1
  • 6
    • 15844406752 scopus 로고    scopus 로고
    • Diverse cell surface protein ectodomains are shed by a system sensitive to metalloproteinase inhibitors
    • Arribas, J., Coodly, L., Vollmer, P., Kishimoto, T.K., Rose-John, S., and Massagué, J. (1997). Diverse cell surface protein ectodomains are shed by a system sensitive to metalloproteinase inhibitors. J. Biol. Chem. 271, 11376-11382.
    • (1997) J. Biol. Chem. , vol.271 , pp. 11376-11382
    • Arribas, J.1    Coodly, L.2    Vollmer, P.3    Kishimoto, T.K.4    Rose-John, S.5    Massagué, J.6
  • 7
    • 0030614352 scopus 로고    scopus 로고
    • NH2-terminal deletion of β-catenin results in stable colocalization of mutant β-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion
    • Barth, A.I. M., Pollack, A.L., Altschuler, Y., Mostov, K.E., and Nelson, W.J. (1997). NH2-terminal deletion of β-catenin results in stable colocalization of mutant β-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion. J. Cell Biol. 136, 693-706.
    • (1997) J. Cell Biol. , vol.136 , pp. 693-706
    • Barth, A.I.M.1    Pollack, A.L.2    Altschuler, Y.3    Mostov, K.E.4    Nelson, W.J.5
  • 9
    • 8044257704 scopus 로고    scopus 로고
    • A metalloproteinase disintegrin that releases tumor-necrosis factor-α from cells
    • Black, R.A., et al. (1997). A metalloproteinase disintegrin that releases tumor-necrosis factor-α from cells. Nature 385, 729-733.
    • (1997) Nature , vol.385 , pp. 729-733
    • Black, R.A.1
  • 10
    • 0021172113 scopus 로고
    • Avian myeloblastosis virus and E26 virus oncogene products are nuclear proteins
    • Boyle, W.J., Lampert, M.A., Lipsick, J.S., and Baluda, M.A. (1984) Avian myeloblastosis virus and E26 virus oncogene products are nuclear proteins. Proc. Natl. Acad. Sci. USA 81, 4265-4269.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 4265-4269
    • Boyle, W.J.1    Lampert, M.A.2    Lipsick, J.S.3    Baluda, M.A.4
  • 11
    • 0028788309 scopus 로고
    • Microfilament reorganization during apoptosis: The role of Gas2, a possible substrate for ICE-like proteases
    • Brancolini, C., Benedetti, M., and Schneider, C. (1995). Microfilament reorganization during apoptosis: the role of Gas2, a possible substrate for ICE-like proteases. EMBO J. 14, 5179-5190.
    • (1995) EMBO J. , vol.14 , pp. 5179-5190
    • Brancolini, C.1    Benedetti, M.2    Schneider, C.3
  • 12
    • 0027255942 scopus 로고
    • Apoptosis and disease
    • Carson, D.A., and Ribeiro, J.M. (1993). Apoptosis and disease. Lancet 341, 1251-1254.
    • (1993) Lancet , vol.341 , pp. 1251-1254
    • Carson, D.A.1    Ribeiro, J.M.2
  • 13
    • 0029890823 scopus 로고    scopus 로고
    • Apopain/CPP 32 cleaves proteins that are essential for cellular repair: A fundamental principle of apoptotic death
    • Casciola-Rosen, L., Nicholson, D.W., Chong, T., Rowan, K.R. Thornberry, N.A., Miller, D.K., and Rosen, A. (1996). Apopain/CPP 32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death. J. Exp. Med. 183, 1957-1964.
    • (1996) J. Exp. Med. , vol.183 , pp. 1957-1964
    • Casciola-Rosen, L.1    Nicholson, D.W.2    Chong, T.3    Rowan, K.R.4    Thornberry, N.A.5    Miller, D.K.6    Rosen, A.7
  • 15
    • 0028919856 scopus 로고
    • A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes
    • Crowe, P.D., Walter, B.N., Mohler, K.M., Otten-Evans, C., Black, R.A., and Ware, C.F. (1995).A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes. J. Exp. Med. 181, 1205-1210.
    • (1995) J. Exp. Med. , vol.181 , pp. 1205-1210
    • Crowe, P.D.1    Walter, B.N.2    Mohler, K.M.3    Otten-Evans, C.4    Black, R.A.5    Ware, C.F.6
  • 16
    • 0029959632 scopus 로고    scopus 로고
    • Specific cleavage of α-fodrin during Fas- and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1β-converting enzyme/CED-3 protease distinct from the poly(ADP-ribose) polymerase protease
    • Cryns, V.L., Bergeron, L., Zhu, H., Li, H., and Yuan, J. (1996). Specific cleavage of α-fodrin during Fas- and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1β-converting enzyme/CED-3 protease distinct from the poly(ADP-ribose) polymerase protease. J. Biol. Chem. 271, 31277-31282.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31277-31282
    • Cryns, V.L.1    Bergeron, L.2    Zhu, H.3    Li, H.4    Yuan, J.5
  • 17
    • 0029972351 scopus 로고    scopus 로고
    • Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions
    • Del Maschio, A., Zanetti, A., Corada, M., Rival, Y., Ruco, L., Lampugnani, M.G., and Dejana, E. (1996). Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions. J. Cell Biol. 135, 497-510.
    • (1996) J. Cell Biol. , vol.135 , pp. 497-510
    • Del Maschio, A.1    Zanetti, A.2    Corada, M.3    Rival, Y.4    Ruco, L.5    Lampugnani, M.G.6    Dejana, E.7
  • 18
    • 0025721095 scopus 로고
    • Membrane proteins with soluble counterparts: Role of proteolysis in the release of transmembrane proteins
    • Ehlers, M.R.W., and Riordan, J.F. (1991). Membrane proteins with soluble counterparts: Role of proteolysis in the release of transmembrane proteins. Biochemistry 30, 10065-10074.
    • (1991) Biochemistry , vol.30 , pp. 10065-10074
    • Ehlers, M.R.W.1    Riordan, J.F.2
  • 19
    • 0028057613 scopus 로고
    • Disruption of epithelial cell-matrix interactions induces apoptosis
    • Frisch, S.M., and Francis, H. (1994). Disruption of epithelial cell-matrix interactions induces apoptosis. J. Cell Biol. 124, 619-626.
    • (1994) J. Cell Biol. , vol.124 , pp. 619-626
    • Frisch, S.M.1    Francis, H.2
  • 20
    • 0028485654 scopus 로고
    • Processing of rumor necrosis factor-α precursor by metalloproteinases
    • Gearing, A.J.H. et al. (1994). Processing of rumor necrosis factor-α precursor by metalloproteinases. Nature 370, 555-557.
    • (1994) Nature , vol.370 , pp. 555-557
    • Gearing, A.J.H.1
  • 21
    • 0021041091 scopus 로고
    • Bovine brain and pituitary fibroblast growth factors: Comparison of their abilities to support the proliferation of human and bovine vascular endothelial cells
    • Gospodarowicz, D., Cheng, J., and Lirette, M. (1983). Bovine brain and pituitary fibroblast growth factors: comparison of their abilities to support the proliferation of human and bovine vascular endothelial cells. J. Cell Biol. 97, 1677-1685.
    • (1983) J. Cell Biol. , vol.97 , pp. 1677-1685
    • Gospodarowicz, D.1    Cheng, J.2    Lirette, M.3
  • 22
    • 0028132171 scopus 로고
    • Classification of signals for blocking apoptosis in vascular endothelial cells
    • Hase, M., Araki, S., Kaji, K., and Hayashi, H. (1994). Classification of signals for blocking apoptosis in vascular endothelial cells. J. Biochem. 116, 905-909.
    • (1994) J. Biochem. , vol.116 , pp. 905-909
    • Hase, M.1    Araki, S.2    Kaji, K.3    Hayashi, H.4
  • 23
    • 0028918891 scopus 로고
    • In vivo analysis of cadherin function in the mouse intestinal epithelium: Essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death
    • Hermiston, M.L., and Gordon, J.I. (1995). In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death. J. Cell Biol. 129, 489-506.
    • (1995) J. Cell Biol. , vol.129 , pp. 489-506
    • Hermiston, M.L.1    Gordon, J.I.2
  • 24
    • 0031025031 scopus 로고    scopus 로고
    • Expression of a disintegrin-like protein in cultured vascular cells and in vivo
    • Herren, B., Raines, E.W., and Ross, R. (1997). Expression of a disintegrin-like protein in cultured vascular cells and in vivo. FASEB J. 11, 173-180.
    • (1997) FASEB J. , vol.11 , pp. 173-180
    • Herren, B.1    Raines, E.W.2    Ross, R.3
  • 26
    • 0345343608 scopus 로고    scopus 로고
    • Nuclear localization of β-catenin by interaction with transcription factor LEF-1
    • Huber, O., Korn, R., McLaughlin, J., Ohsugi, M., Herrmann, B.C., and Kemler, R. (1996). Nuclear localization of β-catenin by interaction with transcription factor LEF-1. Mech. Dev. 59, 3-10.
    • (1996) Mech. Dev. , vol.59 , pp. 3-10
    • Huber, O.1    Korn, R.2    McLaughlin, J.3    Ohsugi, M.4    Herrmann, B.C.5    Kemler, R.6
  • 27
    • 0028572556 scopus 로고
    • E-cadherin and APC compete for the interaction with β-catenin and the cytoskeleton
    • Hülsken, J., Birchmeier, W., and Behrens, J. (1994). E-cadherin and APC compete for the interaction with β-catenin and the cytoskeleton. J. Cell Biol. 127, 2061-2069.
    • (1994) J. Cell Biol. , vol.127 , pp. 2061-2069
    • Hülsken, J.1    Birchmeier, W.2    Behrens, J.3
  • 28
    • 0015822275 scopus 로고
    • Culture of human endothelial cells derived from umbilical veins: Identification by morphologic and immunologic criteria
    • Jaffe, E.A., Nachman, R.L,. Becker, C.G., and Minick, R.C. (1973) Culture of human endothelial cells derived from umbilical veins: identification by morphologic and immunologic criteria. J. Clin. Invest. 52, 2745-2756.
    • (1973) J. Clin. Invest. , vol.52 , pp. 2745-2756
    • Jaffe, E.A.1    Nachman, R.L.2    Becker, C.G.3    Minick, R.C.4
  • 31
    • 0030820875 scopus 로고    scopus 로고
    • Caspase-3-generated fragment of gelsolin: Effector of morphological change in apoptosis
    • Kothakota, S., et al. (1997). Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science 278, 294-298.
    • (1997) Science , vol.278 , pp. 294-298
    • Kothakota, S.1
  • 32
    • 0028900299 scopus 로고
    • The molecular organization of endothelial cell to cell junctions: Differential association of plakoglobin, β-catenin, and α-catenin with vascular endothelial cadherin (VE-cadherin)
    • Lampugnani, M.G., Corada, M., Caveda, L., Breviario, F., Ayalon, O., Geiger, B., and Dejana, E. (1995). The molecular organization of endothelial cell to cell junctions: Differential association of plakoglobin, β-catenin, and α-catenin with vascular endothelial cadherin (VE-cadherin). J. Cell Biol. 129, 203-217.
    • (1995) J. Cell Biol. , vol.129 , pp. 203-217
    • Lampugnani, M.G.1    Corada, M.2    Caveda, L.3    Breviario, F.4    Ayalon, O.5    Geiger, B.6    Dejana, E.7
  • 36
    • 0028483534 scopus 로고
    • Regulation of tumor necrosis factor-α processing by a metalloproteinase inhibitor
    • McGeehan, G.M. et al. (1994). Regulation of tumor necrosis factor-α processing by a metalloproteinase inhibitor. Nature 370, 558-561.
    • (1994) Nature , vol.370 , pp. 558-561
    • McGeehan, G.M.1
  • 37
    • 0028466705 scopus 로고
    • Protection against a lethal dose of endotoxin by an inhibitor of rumor necrosis factor processing
    • Mohler, K.M. et al. (1994). Protection against a lethal dose of endotoxin by an inhibitor of rumor necrosis factor processing. Nature 370, 218-220.
    • (1994) Nature , vol.370 , pp. 218-220
    • Mohler, K.M.1
  • 39
    • 8044250278 scopus 로고    scopus 로고
    • Cloning of a disintegrin-metalloproteinase that processes precursor tumor-necrosis factor-α
    • Moss, M.L. et al. (1997). Cloning of a disintegrin-metalloproteinase that processes precursor tumor-necrosis factor-α. Nature 385, 733-736.
    • (1997) Nature , vol.385 , pp. 733-736
    • Moss, M.L.1
  • 41
    • 0028987249 scopus 로고
    • Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-supressor protein
    • Munemitsu, S., Albert, I., Souza, B., Rubinfeld, B., and Polakis, P. (1995). Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-supressor protein. Proc. Natl. Acad. Sci. USA 92, 3046-3050.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3046-3050
    • Munemitsu, S.1    Albert, I.2    Souza, B.3    Rubinfeld, B.4    Polakis, P.5
  • 44
    • 0029787268 scopus 로고    scopus 로고
    • Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases
    • Orth, K., O'Rourke, K., Salvesen, G.S., and Dixit, V.M. (1996). Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases. J. Biol. Chem. 271, 20977-20980.
    • (1996) J. Biol. Chem. , vol.271 , pp. 20977-20980
    • Orth, K.1    O'Rourke, K.2    Salvesen, G.S.3    Dixit, V.M.4
  • 45
    • 0343196671 scopus 로고    scopus 로고
    • Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drasophila and vertebrate neurogenesis
    • Pan, D., and Rubin, G.M. (1997). Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drasophila and vertebrate neurogenesis. Cell 90, 271-280.
    • (1997) Cell , vol.90 , pp. 271-280
    • Pan, D.1    Rubin, G.M.2
  • 46
    • 0027328498 scopus 로고
    • Purification and characterization of NCAD90, a soluble endogenous form of N-Cadherin, which is generated by proteolysis during retinal development and retains adhesive and neurite-promoting function
    • Paradies, N.E., and Grunwald, G.B. (1993). Purification and characterization of NCAD90, a soluble endogenous form of N-Cadherin, which is generated by proteolysis during retinal development and retains adhesive and neurite-promoting function. J. Neurosci. Res. 36, 33-45.
    • (1993) J. Neurosci. Res. , vol.36 , pp. 33-45
    • Paradies, N.E.1    Grunwald, G.B.2
  • 47
    • 0029981294 scopus 로고    scopus 로고
    • Thrombin-induced increase in endothelial permeability is associated with changes in cell-to-cell junction organization
    • Rabiet, M.J., Plantier, J.L., Rival, Y., Genoux, Y., Lampugnani,. M. G., and Dejana, E. (1996). Thrombin-induced increase in endothelial permeability is associated with changes in cell-to-cell junction organization. Arterioscler. Thromb. Vasc. Biol. 16, 488-496.
    • (1996) Arterioscler. Thromb. Vasc. Biol. , vol.16 , pp. 488-496
    • Rabiet, M.J.1    Plantier, J.L.2    Rival, Y.3    Genoux, Y.4    Lampugnani, M.G.5    Dejana, E.6
  • 48
    • 0028072225 scopus 로고
    • Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells
    • Re, F., Zanetti, A., Sironi, M., Polentarutti, N., Lanfrancone, L., Dejana, E., and Colotta, F. (1994). Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells. J. Cell Biol. 127, 537-546.
    • (1994) J. Cell Biol. , vol.127 , pp. 537-546
    • Re, F.1    Zanetti, A.2    Sironi, M.3    Polentarutti, N.4    Lanfrancone, L.5    Dejana, E.6    Colotta, F.7
  • 49
    • 0026589695 scopus 로고
    • Evidence for endogenous proteases, mRNA level and insulin as multiple mechanisms of N-cadherin down-regulation during retinal development
    • Roark, E.F., Paradies, N.E., Lagunowich, L.A., and Grunwald, G.B. (1992). Evidence for endogenous proteases, mRNA level and insulin as multiple mechanisms of N-cadherin down-regulation during retinal development. Development 114, 973-984.
    • (1992) Development , vol.114 , pp. 973-984
    • Roark, E.F.1    Paradies, N.E.2    Lagunowich, L.A.3    Grunwald, G.B.4
  • 50
    • 0028953279 scopus 로고
    • The APC protein and E-cadherin form similar but independent complexes with α-catenin, β-catenin and plakoglobin
    • Rubinfeld, B., Souza, B., Albert, I., Munemitsu, S., and Polakis, P. (1995). The APC protein and E-cadherin form similar but independent complexes with α-catenin, β-catenin and plakoglobin. J. Biol. Chem. 270, 5549-5555.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5549-5555
    • Rubinfeld, B.1    Souza, B.2    Albert, I.3    Munemitsu, S.4    Polakis, P.5
  • 51
    • 0030900696 scopus 로고    scopus 로고
    • Stabilization of β-catenin by genetic defects in melanoma cell lines
    • Rubinfeld, B., Robbins, P., El-Gamil, M., Albert, I., Porfiri, E., and Polakis, P. (1997). Stabilization of β-catenin by genetic defects in melanoma cell lines. Science 275, 1790-1792.
    • (1997) Science , vol.275 , pp. 1790-1792
    • Rubinfeld, B.1    Robbins, P.2    El-Gamil, M.3    Albert, I.4    Porfiri, E.5    Polakis, P.6
  • 52
    • 0030918572 scopus 로고    scopus 로고
    • Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2
    • Rudel, T., and Bokoch, G.M. (1997). Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science 276, 1571-1574.
    • (1997) Science , vol.276 , pp. 1571-1574
    • Rudel, T.1    Bokoch, G.M.2
  • 53
    • 0029123863 scopus 로고
    • Identification of plakoglobin domains required for association with N-cadherin and a-catenin
    • Sacco, P.A., McGranahan, T.M., Wheelock, M.J., and Johnson, K.R. (1995). Identification of plakoglobin domains required for association with N-cadherin and a-catenin. J. Biol. Chem. 270, 20201-20206.
    • (1995) J. Biol. Chem. , vol.270 , pp. 20201-20206
    • Sacco, P.A.1    McGranahan, T.M.2    Wheelock, M.J.3    Johnson, K.R.4
  • 54
    • 0026583744 scopus 로고
    • Expression of the receptor-linked protein tyrosine phosphatase LAR: Proteolytic cleavage and shedding of the CAM-like extracellular region
    • Streuli, M., Krueger, N.X., Ariniello, P.D., Tang, M., Munro, J.M., Blattler, J.M., Adler, D.A., Disteche, C.M., and Saito, H. (1992). Expression of the receptor-linked protein tyrosine phosphatase LAR: proteolytic cleavage and shedding of the CAM-like extracellular region. EMBO J. 11, 897-907.
    • (1992) EMBO J. , vol.11 , pp. 897-907
    • Streuli, M.1    Krueger, N.X.2    Ariniello, P.D.3    Tang, M.4    Munro, J.M.5    Blattler, J.M.6    Adler, D.A.7    Disteche, C.M.8    Saito, H.9
  • 56
    • 0028943734 scopus 로고
    • Apoptosis in pathogenesis and treatment of disease
    • Thompson, C.B. (1995). Apoptosis in pathogenesis and treatment of disease. Science 267, 1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 57
    • 0030849093 scopus 로고    scopus 로고
    • A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
    • Thornberry, N.A. et al. (1997).A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272, 17907-17911.
    • (1997) J. Biol. Chem. , vol.272 , pp. 17907-17911
    • Thornberry, N.A.1
  • 58
    • 0030054646 scopus 로고    scopus 로고
    • Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene
    • Uyttendaele, H., Marazzi, G., Wu, G., Yan, Q., Sassoon, D., and Kitajewski, J. (1996). Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene. Development 122, 2251-2259.
    • (1996) Development , vol.122 , pp. 2251-2259
    • Uyttendaele, H.1    Marazzi, G.2    Wu, G.3    Yan, Q.4    Sassoon, D.5    Kitajewski, J.6
  • 59
    • 0030999806 scopus 로고    scopus 로고
    • Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF
    • van de Wetering, M., et al. (1997). Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 88, 789-799.
    • (1997) Cell , vol.88 , pp. 789-799
    • Van De Wetering, M.1


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