Perspectives on factor Xa inhibition

Current Medicinal Chemistry

Volumn 8, Issue 2, 2001, Pages 101-119

  Rai, R ^a   Sprengeler, P A ^a   Elrod, K C ^a   Young, W B ^a  

^a Axys Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 [(1 ACETIMIDOYL 3 PYRROLIDINYL)OXY]PHENYL] 3 (7 AMIDINO 2 NAPHTHYL)PROPIONIC ACID; 2,6 BIS(3 AMIDINOPHENOXY) 3,5 DIFLUORO 4 METHYLPYRIDINE; AMIDINE; AMINOPYRIDINE DERIVATIVE; ANTICOAGULANT AGENT; BENZAMIDINE DERIVATIVE; BENZENE DERIVATIVE; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 10A INHIBITOR; BX 5633; FIBRIN; FIBRINOGEN; FX 2212A; HEPARIN; ISOQUINOLINE DERIVATIVE; LIGAND; N [1 (2 AMINOIMINOMETHYL 4 THIENYLMETHYL) 2 OXO 3 PYRROLIDINYL] 7 METHOXY N METHYL 2 NAPHTHALENESULFONAMIDE; N [2 (5 AMIDINO 2 HYDROXYPHENOXY) 3,5 DIFLUORO 6 [3 (1 METHYL 1H 2 IMIDAZOLIN 2 YL)PHENOXY] 4 PYRIDINYL] N METHYLGLYCINE; PIPERIDINE DERIVATIVE; PROTEIN; PROTHROMBIN; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; RPR 130737; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; THROMBIN; TRYPSIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; [N [4 [(1 ACETIMIDOYL 4 PIPERIDYL)OXY]PHENYL] N [(7 AMIDINO 2 NAPHTHYL)METHYL]SULFAMOYL]ACETIC ACID;

ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BLOOD CLOT; BLOOD CLOTTING; CATALYSIS; DRUG EFFECT; DRUG POTENCY; DRUG SELECTIVITY; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STRUCTURE; LIGAND BINDING; NONHUMAN; PHYSIOLOGY; PROTEIN BINDING; THROMBOSIS; TOXICITY;

EID: 0035004409     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867013373822     Document Type: Article

References (119)

1. Current Opinion in cardiovascular, pulmonary and renal investigational drugs