-
1
-
-
0027933180
-
NMR solution structure of the recombinant tick anticoagulant protein (rTAP), a factor Xa inhibitor from the tick Ornithodoros moubata
-
Antuch, W., Guntert, P., Billeter, M., Hawthorne, T., Grossenbacher, H. & Wuthrich, K. (1994). NMR solution structure of the recombinant tick anticoagulant protein (rTAP), a factor Xa inhibitor from the tick Ornithodoros moubata. FEES Letters, 352, 251-257.
-
(1994)
FEES Letters
, vol.352
, pp. 251-257
-
-
Antuch, W.1
Guntert, P.2
Billeter, M.3
Hawthorne, T.4
Grossenbacher, H.5
Wuthrich, K.6
-
2
-
-
0024465016
-
Isolation of human blood coagulation alpha-factor Xa by soybean trypsin inhibitor-Sepharose chromatography and its active-site titration with fluorescein mono-p-guanidinobenzoate
-
Bock, P. E., Craig, P. A., Olson, S. T. & Singh, P. (1989). Isolation of human blood coagulation alpha-factor Xa by soybean trypsin inhibitor-Sepharose chromatography and its active-site titration with fluorescein mono-p-guanidinobenzoate. Arch. Biochem. Biophys. 273, 375-388.
-
(1989)
Arch. Biochem. Biophys.
, vol.273
, pp. 375-388
-
-
Bock, P.E.1
Craig, P.A.2
Olson, S.T.3
Singh, P.4
-
3
-
-
0027050807
-
The refined 1.9 Å X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human a-thrombin. Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, structure-function relationships
-
Bode, W., Turk, D. & Karshikov, A. (1992). The refined 1.9 Å X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human a-thrombin. Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, structure-function relationships. Protein Sci. 1, 426-471.
-
(1992)
Protein Sci.
, vol.1
, pp. 426-471
-
-
Bode, W.1
Turk, D.2
Karshikov, A.3
-
4
-
-
0029923976
-
X-ray structure of active site-inhibited clotting factor Xa
-
Brandstetter, H., Kuehnet, A., Bode, W., Huber, R., Saal, W., Wirthensohn, K. & Engh, A. (1996). X-ray structure of active site-inhibited clotting factor Xa. J. Biol. Chem. 271, 29988-29992.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 29988-29992
-
-
Brandstetter, H.1
Kuehnet, A.2
Bode, W.3
Huber, R.4
Saal, W.5
Wirthensohn, K.6
Engh, A.7
-
5
-
-
0023140814
-
Crystallographic R factor refinement by molecular dynamics
-
Brünger, A. T., Kuriyan, J. & Karplus, M. (1987). Crystallographic R factor refinement by molecular dynamics. Science, 235, 458-460.
-
(1987)
Science
, vol.235
, pp. 458-460
-
-
Brünger, A.T.1
Kuriyan, J.2
Karplus, M.3
-
6
-
-
0030043489
-
Cation-π interactions in chemistry and biology: A new view of benzene, Phe Tyr, and Trp
-
Dougherty, D. A. (1996). Cation-π interactions in chemistry and biology: a new view of benzene, Phe Tyr, and Trp. Science, 271, 163-168.
-
(1996)
Science
, vol.271
, pp. 163-168
-
-
Dougherty, D.A.1
-
7
-
-
0026677581
-
Site-directed analysis of the functional domains in the factor Xa inhibitor tick anticoagulant peptide: Identification of two distinct regions that constitute the enzyme recognition sites
-
Dunwiddie, C. T., Neeper, M. P., Nutt, E. M., Waxman, L., Smith, S. E., Hofmann, K. J., Lumann, P. K., Garsky, V. M. & Vlasuk, G. P. (1992). Site-directed analysis of the functional domains in the factor Xa inhibitor tick anticoagulant peptide: identification of two distinct regions that constitute the enzyme recognition sites. Biochemistry, 31, 12126-12131.
-
(1992)
Biochemistry
, vol.31
, pp. 12126-12131
-
-
Dunwiddie, C.T.1
Neeper, M.P.2
Nutt, E.M.3
Waxman, L.4
Smith, S.E.5
Hofmann, K.J.6
Lumann, P.K.7
Garsky, V.M.8
Vlasuk, G.P.9
-
8
-
-
0028153795
-
Planar stacking interactions of arginine and aromatic side-chains in proteins
-
Flocco, M. M. & Mowbray, S. L. (1994). Planar stacking interactions of arginine and aromatic side-chains in proteins. J. Mol. Biol. 235, 709-717.
-
(1994)
J. Mol. Biol.
, vol.235
, pp. 709-717
-
-
Flocco, M.M.1
Mowbray, S.L.2
-
9
-
-
33947092515
-
Structural basis of the activation and action of trypsin
-
Huber, R. & Bode, W. (1978). Structural basis of the activation and action of trypsin. Ace. Chem. Res. 11, 114-122.
-
(1978)
Ace. Chem. Res.
, vol.11
, pp. 114-122
-
-
Huber, R.1
Bode, W.2
-
11
-
-
0026751368
-
Reaction pathway for inhibition of blood coagulation factor Xa by tick anticoagulant peptide
-
Jordan, S. P., Mao, S. S., Lewis, S. D. & Shafer, J. A. (1992). Reaction pathway for inhibition of blood coagulation factor Xa by tick anticoagulant peptide. Biochemistry, 31, 5374-5380.
-
(1992)
Biochemistry
, vol.31
, pp. 5374-5380
-
-
Jordan, S.P.1
Mao, S.S.2
Lewis, S.D.3
Shafer, J.A.4
-
12
-
-
0030852320
-
X-ray structure of antistasin at 1.9 Å resolution and its modelled complex with blood coagulation factor Xa
-
Lapatto, R., Krengel, U., Schreuder, H. A., Arkema, A., de. Boer, B., Kalk, K. H., Hol, W. G. J., Groothehuis, P. D. J., Mulders, J. W. M., Dijkema, R., Theunissen, H. J. M. & Dijkstra, B. W. (1997). X-ray structure of antistasin at 1.9 Å resolution and its modelled complex with blood coagulation factor Xa. EMBO J. 16, 5151-5161.
-
(1997)
EMBO J.
, vol.16
, pp. 5151-5161
-
-
Lapatto, R.1
Krengel, U.2
Schreuder, H.A.3
Arkema, A.4
De Boer, B.5
Kalk, K.H.6
Hol, W.G.J.7
Groothehuis, P.D.J.8
Mulders, J.W.M.9
Dijkema, R.10
Theunissen, H.J.M.11
Dijkstra, B.W.12
-
14
-
-
0026502250
-
Largescale purification and characterization of recombinant tick anticoagulant peptide
-
Lehman, E. D., Schaefer, T. F., Przysiecki, C. T., Joyce, J. G., Bailey, F. J. & Schulman, C. A. (1992). Largescale purification and characterization of recombinant tick anticoagulant peptide. J. Chromatog. 574, 225-235.
-
(1992)
J. Chromatog.
, vol.574
, pp. 225-235
-
-
Lehman, E.D.1
Schaefer, T.F.2
Przysiecki, C.T.3
Joyce, J.G.4
Bailey, F.J.5
Schulman, C.A.6
-
15
-
-
14744306357
-
A novel process for the large-scale purification of recombinant tick anticoagulant peptide using perfusion chromatography
-
Lehman, E. D., Joyce, J. G., Freymeyer, D. K., Bailey, F. J., Herber, W. K. & Miller, W. J. (1993). A novel process for the large-scale purification of recombinant tick anticoagulant peptide using perfusion chromatography. Bio/Technology, 11, 207-212.
-
(1993)
Bio/Technology
, vol.11
, pp. 207-212
-
-
Lehman, E.D.1
Joyce, J.G.2
Freymeyer, D.K.3
Bailey, F.J.4
Herber, W.K.5
Miller, W.J.6
-
16
-
-
0028936409
-
NMR structure determination of tick anticoagulant peptide (TAP)
-
Lim-Wilby, M. S. L., Hallenga, K., Maeyer, M. D., Lasters, I., Vlasuk, G. P. & Brunck, T. K. (1995). NMR structure determination of tick anticoagulant peptide (TAP). Protein Sci. 4, 178-186.
-
(1995)
Protein Sci.
, vol.4
, pp. 178-186
-
-
Lim-Wilby, M.S.L.1
Hallenga, K.2
Maeyer, M.D.3
Lasters, I.4
Vlasuk, G.P.5
Brunck, T.K.6
-
17
-
-
0031050773
-
Molecular design and characterization of an α-thrombin inhibitor containing a novel p1 moiety
-
Malikayil, J. A., Burkhart, J. P., Schreuder, H. A., Broersma, R. J., Tardif, C., Kutcher, L. W., Mehdi, S., Schatzman, G. L., Neises, B. & Peet, N. P. (1997). Molecular design and characterization of an α-thrombin inhibitor containing a novel p1 moiety. Biochemistry, 36, 1034-1040.
-
(1997)
Biochemistry
, vol.36
, pp. 1034-1040
-
-
Malikayil, J.A.1
Burkhart, J.P.2
Schreuder, H.A.3
Broersma, R.J.4
Tardif, C.5
Kutcher, L.W.6
Mehdi, S.7
Schatzman, G.L.8
Neises, B.9
Peet, N.P.10
-
18
-
-
0028930192
-
Identification and characterization of variants of tick anticoagulant peptide and increased inhibitory potency toward human factor Xa
-
Mao, S. S., Huang, J., Welebob, C., Neeper, M. P., Garsky, V. M. & Shafer, J. A. (1995). Identification and characterization of variants of tick anticoagulant peptide and increased inhibitory potency toward human factor Xa. Biochemistry, 34, 5098-5103.
-
(1995)
Biochemistry
, vol.34
, pp. 5098-5103
-
-
Mao, S.S.1
Huang, J.2
Welebob, C.3
Neeper, M.P.4
Garsky, V.M.5
Shafer, J.A.6
-
19
-
-
0002452464
-
Oscillation data reduction program
-
Sawyer, L., Isaacs, N. & Bailey, S., eds, SERC Daresbury Laboratory, Warrington, UK
-
Otwinowski, Z. (1993). Oscillation data reduction program. In Proceedings of the CCP4 Study Weekend: Data Collection and Processing (Sawyer, L., Isaacs, N. & Bailey, S., eds), pp. 56-62, SERC Daresbury Laboratory, Warrington, UK.
-
(1993)
Proceedings of the CCP4 Study Weekend: Data Collection and Processing
, pp. 56-62
-
-
Otwinowski, Z.1
-
20
-
-
0025163058
-
Characterization of recombinant tick anticoagulant peptide
-
Neeper, M. P., Waxman, L., Smith, D. E., Schulman, C. A., Sardana, M., Ellis, R. E., Schaeffer, L. W., Siegel, P. K. S. & Vlasuk, G. P. (1990). Characterization of recombinant tick anticoagulant peptide. J. Biol. Chem. 265, 17746-17752.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 17746-17752
-
-
Neeper, M.P.1
Waxman, L.2
Smith, D.E.3
Schulman, C.A.4
Sardana, M.5
Ellis, R.E.6
Schaeffer, L.W.7
Siegel, P.K.S.8
Vlasuk, G.P.9
-
21
-
-
0027304964
-
Structure of human des(1-45) factor Xa at 2.2 Å resolution
-
Padmanabhan, K., Padmanabhan, K. P., Tulinsky, A., Park, C. H., Bode, W., Huber, R., Blankenslip, D. T., Cardin, A. D. & Kisiel, W. (1993). Structure of human des(1-45) factor Xa at 2.2 Å resolution. J. Mol. Biol. 232, 947-966.
-
(1993)
J. Mol. Biol.
, vol.232
, pp. 947-966
-
-
Padmanabhan, K.1
Padmanabhan, K.P.2
Tulinsky, A.3
Park, C.H.4
Bode, W.5
Huber, R.6
Blankenslip, D.T.7
Cardin, A.D.8
Kisiel, W.9
-
22
-
-
0025329390
-
The structure of a complex of recombinant hirudin and human α-thrombin
-
Rydel, T. J., Ravichandran, K. G., Tulinsky, A., Bode, W., Huber, R., Roitsch, C. & Fenton, J. W., II (1990). The structure of a complex of recombinant hirudin and human α-thrombin. Science, 249, 277-280.
-
(1990)
Science
, vol.249
, pp. 277-280
-
-
Rydel, T.J.1
Ravichandran, K.G.2
Tulinsky, A.3
Bode, W.4
Huber, R.5
Roitsch, C.6
Fenton J.W. II7
-
23
-
-
0025866812
-
Refined structure of the hirudin-thrombin complex
-
Rydel, T. J., Tulinsky, A., Bode, W. & Huber, R. (1991). Refined structure of the hirudin-thrombin complex. J. Mol. Biol. 221, 583-601.
-
(1991)
J. Mol. Biol.
, vol.221
, pp. 583-601
-
-
Rydel, T.J.1
Tulinsky, A.2
Bode, W.3
Huber, R.4
-
24
-
-
0028824422
-
Crystal structures of factor Xa specific inhibitors in complex with trypsin: Structural grounds for inhibition of factor Xa and selectivity against thrombin
-
Stubbs, M. T., Huber, R. & Bode, W. (1995). Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin. FEBS Letters, 375, 103-107.
-
(1995)
FEBS Letters
, vol.375
, pp. 103-107
-
-
Stubbs, M.T.1
Huber, R.2
Bode, W.3
-
25
-
-
0029957955
-
The ornithodorin-thrombin crystal structure, a key to the TAP enigma?
-
van de Locht, A., Stubbs, M. T., Bode, W., Friedrich, T., Bollschweiler, C., Hoftken, W. & Huber, R. (1996). The ornithodorin-thrombin crystal structure, a key to the TAP enigma? EMBO J. 15, 6011-6017.
-
(1996)
EMBO J.
, vol.15
, pp. 6011-6017
-
-
Van De Locht, A.1
Stubbs, M.T.2
Bode, W.3
Friedrich, T.4
Bollschweiler, C.5
Hoftken, W.6
Huber, R.7
-
26
-
-
0025375504
-
Tick anticoagulant peptide (tap) is a novel inhibitor of blood coagulation factor Xa
-
Waxman, L., Smith, D. E., Arcuri, K. E. & Vlasuk, G. P. (1990). Tick anticoagulant peptide (tap) is a novel inhibitor of blood coagulation factor Xa. Science, 248, 593-596.
-
(1990)
Science
, vol.248
, pp. 593-596
-
-
Waxman, L.1
Smith, D.E.2
Arcuri, K.E.3
Vlasuk, G.P.4
-
27
-
-
0030586091
-
Antithrombotic actions of selective inhibitors of blood coagulation factor Xa in rat models of thrombosis
-
Wong, P. C., Crain, E. J., Nguan, O., Watson, C. A. & Racanelli, A. (1996). Antithrombotic actions of selective inhibitors of blood coagulation factor Xa in rat models of thrombosis. Thrombosis Res. 83, 117-126.
-
(1996)
Thrombosis Res.
, vol.83
, pp. 117-126
-
-
Wong, P.C.1
Crain, E.J.2
Nguan, O.3
Watson, C.A.4
Racanelli, A.5
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