메뉴 건너뛰기




Volumn 122, Issue 1-2, 1998, Pages 127-133

DX9065a, an Xa inhibitor, inhibits prothrombin-induced A549 lung adenocarcinoma cell proliferation

Author keywords

Cancer procoagulant; DX9065a; Thrombin

Indexed keywords

2 [4 [(1 ACETIMIDOYL 3 PYRROLIDINYL)OXY]PHENYL] 3 (7 AMIDINO 2 NAPHTHYL)PROPIONIC ACID; ANTIMITOTIC AGENT; BLOOD CLOTTING FACTOR 10A; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; PROTHROMBIN; THROMBIN; THROMBIN RECEPTOR;

EID: 0032498258     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(97)00379-0     Document Type: Article
Times cited : (10)

References (22)
  • 2
    • 0027492461 scopus 로고
    • Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor
    • McNamara C.A., Sarembock I.J., Gimple L.W., Fenton J.W., Coughlin S.R., Owens G.K. Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor. J. Clin. Invest. 91:1993;94-98.
    • (1993) J. Clin. Invest. , vol.91 , pp. 94-98
    • McNamara, C.A.1    Sarembock, I.J.2    Gimple, L.W.3    Fenton, J.W.4    Coughlin, S.R.5    Owens, G.K.6
  • 3
    • 0023186924 scopus 로고
    • Two growth factor signalling pathways in fibroblasts distinguished by pertussis toxin
    • Chambard J.C., Paris S., L'Allemain G., Pouyssegur J. Two growth factor signalling pathways in fibroblasts distinguished by pertussis toxin. Nature. 326:1987;800-803.
    • (1987) Nature , vol.326 , pp. 800-803
    • Chambard, J.C.1    Paris, S.2    L'Allemain, G.3    Pouyssegur, J.4
  • 4
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu T.K., Hung D.T., Wheaton V.I., Coughlin S.R. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell. 64:1991;1057-1068.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.K.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 5
    • 0018622772 scopus 로고
    • The contribution of bovine factor V and factor Va to the activity of prothrombinase
    • Nesheim M.E., Taswell J.B., Mann K.G. The contribution of bovine factor V and factor Va to the activity of prothrombinase. J. Biol. Chem. 254:1979;10952-10962.
    • (1979) J. Biol. Chem. , vol.254 , pp. 10952-10962
    • Nesheim, M.E.1    Taswell, J.B.2    Mann, K.G.3
  • 6
    • 0028559218 scopus 로고
    • Activation of prothrombin by a novel membrane-associated protease. An alternative pathway for thrombin generation independent of the coagulation cascade
    • Sekiya F., Usui H., Inoue K., Fukudome K., Morita T. Activation of prothrombin by a novel membrane-associated protease. An alternative pathway for thrombin generation independent of the coagulation cascade. J. Biol. Chem. 269:1994;32441-32445.
    • (1994) J. Biol. Chem. , vol.269 , pp. 32441-32445
    • Sekiya, F.1    Usui, H.2    Inoue, K.3    Fukudome, K.4    Morita, T.5
  • 8
    • 0022371596 scopus 로고
    • The turnover of thrombin-thrombomodulin complex in cultured human umbilical vein endothelial cells and A549 lung cancer cells. Endocytosis and degradation of thrombin
    • Maruyama I., Majerus P.W. The turnover of thrombin-thrombomodulin complex in cultured human umbilical vein endothelial cells and A549 lung cancer cells. Endocytosis and degradation of thrombin. J. Biol. Chem. 260:1985;15432-15438.
    • (1985) J. Biol. Chem. , vol.260 , pp. 15432-15438
    • Maruyama, I.1    Majerus, P.W.2
  • 10
    • 0022358277 scopus 로고
    • Measurement of cell proliferation in microculture using Hoechst 33342 for the rapid semiautomated microfluorimetric determination of chromatin DNA
    • Richards W.L., Song M.K., Krutzsch H., Evarts R.P., Marsden E., Thorgeirsson S.S. Measurement of cell proliferation in microculture using Hoechst 33342 for the rapid semiautomated microfluorimetric determination of chromatin DNA. Exp. Cell. Res. 159:1985;235-246.
    • (1985) Exp. Cell. Res. , vol.159 , pp. 235-246
    • Richards, W.L.1    Song, M.K.2    Krutzsch, H.3    Evarts, R.P.4    Marsden, E.5    Thorgeirsson, S.S.6
  • 11
    • 0028054862 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet beta-cells
    • Yada T., Sakurada M., Ihida K., Nakata M., Murata F., Arimura A., Kikuchi M. Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet beta-cells. J. Biol. Chem. 269:1994;1290-1293.
    • (1994) J. Biol. Chem. , vol.269 , pp. 1290-1293
    • Yada, T.1    Sakurada, M.2    Ihida, K.3    Nakata, M.4    Murata, F.5    Arimura, A.6    Kikuchi, M.7
  • 13
    • 0028225565 scopus 로고
    • Thrombin receptor agonist peptide decreases thrombomodulin activity in cultured human umbilical vein endothelial cells
    • Maruyama Y., Maruyama I., Soejima Y. Thrombin receptor agonist peptide decreases thrombomodulin activity in cultured human umbilical vein endothelial cells. Biochem. Biophys. Res. Commun. 199:1994;1262-1269.
    • (1994) Biochem. Biophys. Res. Commun. , vol.199 , pp. 1262-1269
    • Maruyama, Y.1    Maruyama, I.2    Soejima, Y.3
  • 14
    • 0026075254 scopus 로고
    • 'Thrombin' receptor-directed ligand accounts for activation by thrombin of platelet phospholipase C and accumulation of 3-phosphorylated phosphoinositides
    • Huang R.S., Sorisky A., Church W.R., Simons E.R., Rittenhouse S.E. 'Thrombin' receptor-directed ligand accounts for activation by thrombin of platelet phospholipase C and accumulation of 3-phosphorylated phosphoinositides. J. Biol. Chem. 266:1991;18435-18438.
    • (1991) J. Biol. Chem. , vol.266 , pp. 18435-18438
    • Huang, R.S.1    Sorisky, A.2    Church, W.R.3    Simons, E.R.4    Rittenhouse, S.E.5
  • 15
    • 0027165150 scopus 로고
    • The mitogen-activated protein kinase signal transduction pathway
    • Davis R.J. The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem. 268:1993;14553-14556.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14553-14556
    • Davis, R.J.1
  • 16
    • 0023105461 scopus 로고
    • Thrombosis and cancer
    • Dvorak H.F. Thrombosis and cancer. Hum. Pathol. 18:1987;275-284.
    • (1987) Hum. Pathol. , vol.18 , pp. 275-284
    • Dvorak, H.F.1
  • 17
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • Dvorak H.M. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N. Engl. J. Med. 315:1986;1650-1659.
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1650-1659
    • Dvorak, H.M.1
  • 18
    • 0029858997 scopus 로고    scopus 로고
    • Characterization of an inducible endothelial cell prothrombin activator
    • Liu L., Rodgers G.M. Characterization of an inducible endothelial cell prothrombin activator. Blood. 88:1996;2989-2994.
    • (1996) Blood , vol.88 , pp. 2989-2994
    • Liu, L.1    Rodgers, G.M.2
  • 19
    • 0027216694 scopus 로고
    • Phospholipase A2-induced stimulation of A549 lung adenocarcinoma cell line proliferation
    • Tokumoto H., Croxtall J.D., Choudhury Q., Flower R.J. Phospholipase A2-induced stimulation of A549 lung adenocarcinoma cell line proliferation. Biochem. Biophys. Acta. 1169:1993;236-242.
    • (1993) Biochem. Biophys. Acta , vol.1169 , pp. 236-242
    • Tokumoto, H.1    Croxtall, J.D.2    Choudhury, Q.3    Flower, R.J.4
  • 20
    • 0028206839 scopus 로고
    • Differential role of extra- and intracellular calcium in bradykinin and interleukin 1 alpha stimulation of arachidonic acid release from A549 cells
    • Tokumoto H., Croxtall J.D., Flower R.J. Differential role of extra- and intracellular calcium in bradykinin and interleukin 1 alpha stimulation of arachidonic acid release from A549 cells. Biochem. Biophys. Acta. 1211:1994;301-309.
    • (1994) Biochem. Biophys. Acta , vol.1211 , pp. 301-309
    • Tokumoto, H.1    Croxtall, J.D.2    Flower, R.J.3
  • 21
    • 0025972602 scopus 로고
    • Thrombin stimulation of synthesis and secretion of fibronectin by human A549 epithelial cells and mouse LB fibroblasts
    • Kang Y.H., Kedar V.P., Maheshwari R.K. Thrombin stimulation of synthesis and secretion of fibronectin by human A549 epithelial cells and mouse LB fibroblasts. J. Histochem. Cytochem. 39:1991;413-423.
    • (1991) J. Histochem. Cytochem. , vol.39 , pp. 413-423
    • Kang, Y.H.1    Kedar, V.P.2    Maheshwari, R.K.3
  • 22
    • 0019503942 scopus 로고
    • A factor X-activating cysteine protease from malignant tissue
    • Gordon S.G., Cross B.A. A factor X-activating cysteine protease from malignant tissue. J. Clin. Invest. 67:1981;1665-1671.
    • (1981) J. Clin. Invest. , vol.67 , pp. 1665-1671
    • Gordon, S.G.1    Cross, B.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.