Structure/function analyses of recombinant variants of human factor Xa: Factor Xa incorporation into prothrombinase on the thrombin-activated platelet surface is not mimicked by synthetic phospholipid vesicles

Biochemistry

Volumn 37, Issue 14, 1998, Pages 5029-5038

  Larson, Peter J ^a,b   Camire, Rodney M ^c   Wong, Dore ^b   Fasano, Nicholas C ^b   Monroe, Dougald M ^d   Tracy, Paula B ^c   High, Katherine A ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c UNIVERSITY OF VERMONT   (United States)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; BLOOD CLOTTING FACTOR 10A; GLUTAMIC ACID; HYDROXYAPATITE; PHOSPHOLIPID; PROTEIN; RECOMBINANT BLOOD CLOTTING FACTOR 10A; SNAKE VENOM; THROMBIN; UNCLASSIFIED DRUG; VITAMIN K GROUP;

ARTICLE; CARBOXYLATION; COMPLEX FORMATION; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOAFFINITY CHROMATOGRAPHY; PHOSPHOLIPID VESICLE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; THROMBOCYTE;

BLOOD COAGULATION; BLOOD PLATELETS; CELL LINE; CELL MEMBRANE; FACTOR XA; HUMANS; HYDROLYSIS; MOLECULAR MIMICRY; MUTAGENESIS, SITE-DIRECTED; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN; THROMBOPLASTIN;

SERPENTES; VIPER;

EID: 0032492690     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972428p     Document Type: Article

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