Structural basis for chemical inhibition of human blood coagulation factor Xa

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 12, 1998, Pages 6630-6635

  Kamata, Kenji ^a,b   Kawamoto, Hiroshi ^b   Honma, Teruki ^b   Iwama, Toshiharu ^b   Kim, Sung Hou ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BANYU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

(3' AMIDINO 3 BIPHENYLYL) 5 (4 PYRIDYLAMINO)PENTANOIC ACID; 2 [4 [(1 ACETIMIDOYL 3 PYRROLIDINYL)OXY]PHENYL] 3 (7 AMIDINO 2 NAPHTHYL)PROPIONIC ACID; BLOOD CLOTTING FACTOR 10A; THROMBIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; BLOOD CLOTTING; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; HUMAN; HUMAN CELL; HUMAN TISSUE; INHIBITION KINETICS; PRIORITY JOURNAL; PROTEIN STRUCTURE;

BINDING SITES; BIPHENYL COMPOUNDS; ENZYME INHIBITORS; FACTOR XA; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

OXY;

EID: 0032499683     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.12.6630     Document Type: Article

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