-
2
-
-
0345593816
-
Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts
-
(1999)
J. Cell Biol.
, vol.144
, pp. 1019-1031
-
-
Angers-Loustau, A.1
Cote, J.F.2
Charest, A.3
Dowbenko, D.4
Spencer, S.5
Lasky, L.A.6
Tremblay, M.L.7
-
7
-
-
0032403139
-
Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis
-
(1998)
Cancer Res.
, vol.58
, pp. 5285-5290
-
-
Davies, M.A.1
Lu, Y.2
Sano, T.3
Fang, X.4
Tang, P.5
LaPushin, R.6
Koul, D.7
Bookstein, R.8
Stokoe, D.9
Yung, W.K.10
-
8
-
-
0033152165
-
Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN
-
(1999)
Cancer Res.
, vol.59
, pp. 2551-2556
-
-
Davies, M.A.1
Koul, D.2
Dhesi, H.3
Berman, R.4
McDonnell, T.J.5
McConkey, D.6
Yung, W.K.7
Steck, P.A.8
-
28
-
-
0033376684
-
PTEN affects cell size, cell proliferation and apoptosis during Drosolphila eye development
-
(1999)
Development
, vol.126
, pp. 5365-5372
-
-
Huang, H.1
Potter, C.J.2
Tao, W.3
Li, D.-M.4
Brogiolo, W.5
Hafen, E.6
Sun, H.7
Xu, T.8
-
29
-
-
0034735594
-
ACAPs are arf6 GTPase-activating proteins that function in the cell periphery
-
(2000)
J. Cell Biol.
, vol.151
, pp. 627-638
-
-
Jackson, T.R.1
Brown, F.D.2
Nie, Z.3
Miura, K.4
Foroni, L.5
Sun, J.6
Hsu, V.W.7
Donaldson, J.G.8
Randazzo, P.A.9
-
31
-
-
0001764656
-
Phosphoinositides determine specificity of the guanine-nucleotide exchange activity of cytohesin-1 for ADP-ribosylation factors derived from a mammalian expression system
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 3784-3791
-
-
Knorr, T.1
Nagel, W.2
Kolanus, W.3
-
33
-
-
0033615538
-
Crystal structure of the PTEN tumor suppressor: Implications for its phosphoinositide phosphatase activity and membrane association
-
(1999)
Cell
, vol.99
, pp. 323-334
-
-
Lee, J.O.1
Yang, H.2
Georgescu, M.M.3
Di Cristofano, A.4
Maehama, T.5
Shi, Y.6
Dixon, J.E.7
Pandolfi, P.8
Pavletich, N.P.9
-
36
-
-
0031001041
-
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta
-
(1997)
Cancer Res.
, vol.57
, pp. 2124-2129
-
-
Li, D.M.1
Sun, H.2
-
38
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.I.6
Puc, J.7
Miliaresis, C.8
Rodgers, L.9
McCombie, R.10
-
40
-
-
0033994516
-
Form, function, and regulation of protein tyrosine phosphatases and their involvement in human diseases
-
(2000)
Semin. Immunol.
, vol.12
, pp. 75-84
-
-
Li, L.1
Dixon, J.E.2
-
42
-
-
0343183328
-
Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases
-
(2000)
Curr. Biol.
, vol.10
, pp. 401-404
-
-
Liliental, J.1
Moon, S.Y.2
Lesche, R.3
Mamillapalli, R.4
Li, D.5
Zheng, Y.6
Sun, H.7
Wu, H.8
-
43
-
-
0033604468
-
The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells
-
(1999)
Oncogene
, vol.18
, pp. 7034-7045
-
-
Lu, Y.1
Lin, Y.Z.2
LaPushin, R.3
Cuevas, B.4
Fang, X.5
Yu, S.X.6
Davies, M.A.7
Khan, H.8
Furui, T.9
Mao, M.10
-
44
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
48
-
-
0030837555
-
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual- specificity phosphatase
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9052-9057
-
-
Myers, M.P.1
Stolarov, J.P.2
Eng, C.3
Li, J.4
Wang, S.I.5
Wigler, M.H.6
Parsons, R.7
Tonks, N.K.8
-
49
-
-
0032506011
-
The lipid phosphatase activity of PTEN is critical for its tumor supressor function
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13513-13518
-
-
Myers, M.P.1
Pass, I.2
Batty, I.H.3
Van der Kaay, J.4
Stolarov, J.P.5
Hemmings, B.A.6
Wigler, M.H.7
Downes, C.P.8
Tonks, N.K.9
-
52
-
-
0029039421
-
Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors
-
(1995)
Cancer Res.
, vol.55
, pp. 2752-2755
-
-
Owens, L.V.1
Xu, L.2
Craven, R.J.3
Dent, G.A.4
Weiner, T.M.5
Kornberg, L.6
Liu, E.T.7
Cance, W.G.8
-
55
-
-
13044250465
-
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1563-1568
-
-
Podsypanina, K.1
Ellenson, L.H.2
Nemes, A.3
Gu, J.4
Tamura, M.5
Yamada, K.M.6
Cordon-Cardo, C.7
Catoretti, G.8
Fisher, P.E.9
Parsons, R.10
-
61
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
de la Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
Sasaki, T.6
Ruland, J.7
Penninger, J.M.8
Siderovski, D.P.9
Mak, T.W.10
-
62
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
(1997)
Nat. Genet.
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.4
Lin, H.5
Ligon, A.H.6
Langford, L.A.7
Baumgard, M.L.8
Hattier, T.9
Davis, T.10
-
63
-
-
13044305289
-
PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5-trisphosphate and Akt/protein kinase B signaling pathway
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6199-6204
-
-
Sun, H.1
Lesche, R.2
Li, D.M.3
Liliental, J.4
Zhang, H.5
Gao, J.6
Gavrilova, N.7
Mueller, B.8
Liu, X.9
Wu, H.10
-
64
-
-
13144249184
-
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
-
(1998)
Curr. Biol.
, vol.8
, pp. 1169-1178
-
-
Suzuki, A.1
de la Pompa, J.L.2
Stambolic, V.3
Elia, A.J.4
Sasaki, T.5
del Barco Barrantes, I.6
Ho, A.7
Wakeham, A.8
Itie, A.9
Khoo, W.10
-
65
-
-
0032486198
-
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
-
(1998)
Science
, vol.280
, pp. 1614-1617
-
-
Tamura, M.1
Gu, J.2
Matsumoto, K.3
Aota, S.4
Parsons, R.5
Yamada, K.M.6
-
69
-
-
0033811556
-
5′ phospholipid phosphatase SHIP-2 causes protein kinase B inactivation and cell cycle arrest in glioblastoma cells
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 6860-6871
-
-
Taylor, V.1
Wong, M.2
Brandts, C.3
Reilly, L.4
Dean, N.M.5
Cowsert, L.M.6
Moodie, S.7
Stokoe, D.8
-
71
-
-
0030297552
-
From form to function: Signaling by protein tyrosine phosphatases
-
(1996)
Cell
, vol.87
, pp. 365-368
-
-
Tonks, N.K.1
Neel, B.G.2
-
72
-
-
0035847102
-
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 993-998
-
-
Torres, J.1
Pulido, R.2
-
75
-
-
0034607876
-
GIT proteins, a novel family of phosphatidylinositol 3,4, 5- trisphophate-stimulated GTPase-activating proteins for ARF6
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13901-13906
-
-
Vitale, N.1
Patton, W.A.2
Moss, J.3
Vaughan, M.4
Lefkowitz, R.J.5
Premont, R.T.6
-
79
-
-
0032574718
-
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 5246-5250
-
-
Whang, Y.E.1
Wu, X.2
Suzuki, H.3
Reiter, R.E.4
Tran, C.5
Vessella, R.L.6
Said, J.W.7
Isaacs, W.B.8
Sawyers, C.L.9
-
80
-
-
0034636038
-
Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4233-4238
-
-
Wu, X.1
Hepner, K.2
Castelino-Prabhu, S.3
Do, D.4
Kaye, M.B.5
Yuan, X.J.6
Wood, J.7
Ross, C.8
Sawyers, C.L.9
Whang, Y.E.10
-
81
-
-
0034647496
-
Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 21477-21485
-
-
Wu, Y.1
Dowbenko, D.2
Spencer, S.3
Laura, R.4
Lee, J.5
Gu, Q.6
Lasky, L.A.7
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