Absence of PTEN/MMAC1 pseudogene in mice

DNA and Cell Biology

Volumn 19, Issue 5, 2000, Pages 301-305

  Kwabi Addo, Bernard ^a   Thompson, Timothy C ^a   Ittmann, Michael ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATASE;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; GENE MAPPING; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PSEUDOGENE; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE;

ANIMALS; BLOTTING, SOUTHERN; DNA MUTATIONAL ANALYSIS; GENES, TUMOR SUPPRESSOR; HUMANS; MICE; PHOSPHORIC MONOESTER HYDROLASES; POLYMERASE CHAIN REACTION; PSEUDOGENES; PTEN PHOSPHOHYDROLASE; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA; RODENTIA;

EID: 0033855815     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/10445490050021212     Document Type: Article

References (18)

1. CAIRNS, P., OKAMI, K., HALACHMI, N., ESTELLER, M., HERMAN, J., JEN, J., ISSACS, W., BOVA, S., and SIDRANSKY, D. (1997). Frequent inactivation of PTEN/MMAC1 in primary prostate cancer. Cancer Res. 57, 4997-5000.
2. DAHIA, P.L.M., FITZGERALD, M.G., ZHANG, X., MARSH, D.J., ZHENG, Z., PIETSCH, T., VON DEIMLING, A., HALUSKA, F.G., HABER, D.A., and ENG, C. (1998). A highly conserved processed PTEN pseudogene is located on chromosome band 9p21. Oncogene 16, 2403-2406.
3. DI CRISTOFANO, A., PESCE, B., CORDON-CARDO, C., and PANDOLFI, P.P. (1998). PTEN is essential for embryonic development and tumor suppression. Nature Genet. 19, 348-355.
4. FUJII, G., MORIMOTO, A., BERSON, A., and BOLEN, J. (1999). Transcriptional analysis of the PTEN/MMAC1 pseudogene ψPTEN. Oncogene 18, 1765-1769
5. GULDBERG, P., THOR STRATEN, P., BIRCK, A., AHRENKIEL, V., KIRKIN, A.F., and ZEUTHEN, J. (1997). Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma. Cancer Res. 57, 3660-3663.
6. HANSEN, G.M., and JUSTICE, M.J. (1997). PTEN, a candidate tumor suppressor gene, maps to mouse chromosome 19. Mamm. Genome 9, 88-90.
7. KONG, D., SUZUKI, A., ZOU, T.T., SAKURADA, A., KEMP, L.W., WAKATSUKI, S., YOKOYAMA, T., YAMAKAWA, H., FURUKAWA, T., SATO, M., OHUCHI, N., SATO, S., YIN, J., WANG, S., ABRAHAM, J., SOUZA, R., SMOLINSKI, K., MELTZER, S., and HORII, A. (1997). PTEN1 is frequently mutated in primary endometrial carcinomas. Nature Genet. 17, 143-144.
8. LI, J., YEN, C., LIAW, D., PODSYPANINA, K., BOSE, S., WANG, S.I., PUC, J., MILIARESIS, C., RODGERS, L., MCCOMBIE, R., BIGNER, S., GIOVANELLA, B., ITTMANN, M., TYCKO, B., HIBSHOOSH, H., WIGLER, M., and PARSONS, R. (1997). PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast and prostate cancer. Science 275, 1943-1947.
9. LIAW, D., MARSH, D.J., LI, J., DAHIA, P.L.M., WANG, S.I., ZHENG, Z., BOSE, S., CALL, K.M., TSOU, H., PEACOCK, M., ENG, C. and PARSONS, R. (1997) Germline mutations of the PTEN gene is Cowden disease, an inherited breast and thyroid cancer syndrome. Nature Genet. 16, 64-67.
10. MARSH, D.J., DAHIA, P.L.M., ZHENG, Z., LIAW, D., PARSONS, R., GORIN, R.J. and ENG, C. (1997) Germline mutations in PTEN are present in Bannayan-Zonana syndrome. Nature Genet. 16, 333-334.
11. RHEI, E., KANG, L., BOGOMOLNIY, F., FEDERICI, M.G., BERGEN, P.I., and BOYD, J. (1997). Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas. Cancer Res. 57, 3657-3659.
12. STECK, P.A., PERSHOUSE, M.A., JASSER, S.A., YUNG, W.K., LIN, H., LIGON, A.H., LANGFORD, L.A., BAUMGARD, M.L., HATTIER, T., DAVIS, T., FRYE, C., HU, R., SWEDLUND, B., TENG, D.H., and TAVTIGIAN, S.V. (1997). Identification of a candidate tumor suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nature Genet. 15, 356-362.
13. THOMPSON, T.C., PARK, S.H., TIMME, T.L., REN, C., EASTHAM, J.A., DONEHOWER, L.A., BRADLEY, A., KADMON, D., and YANG, G. (1995). Loss of p53 function leads to metastasis in ras+myc-initiated mouse prostate cancer. Oncogene 10, 869-879.
14. VANIN, E.F. (1985). Processed pseudogenes: Characteristics and evolution. Annu. Rev. Genet. 19, 253-272.
15. WANG, S.I., PARSONS, R., and ITTMANN, M. (1998). Homozygous deletion of the PTEN tumor suppressor gene in a subset of prostate adenocarcinomas. Clin. Cancer Res. 4, 811-815.
16. WHANG, Y.E., WU, X., and SAWYERS, C.L. (1998). Identification of a pseudogene that can masquerade as a mutant allele of the PTEN/MMAC1 tumor suppressor gene. J. Natl. Cancer Inst. 90, 859-861.
17. WEINER, A.M., DEININGER, P.L., and EFSTRATIADIS, A. (1986). Nonviral retroposons: Genes, pseudogenes, and transposable elements generated by the reverse flow of genetic information. Annu. Rev. Biochem. 55, 631-661.
18. YANG, G., TRUONG, L., TIMME, T., REN, C., WHEELER, T., PARK, S., NASU, Y., BANGMA, C., KATTAN, M., SCARDINO, P., and THOMPSON, T. (1998). Elevated expression of calveolin is associated with prostate and breast cancer. Clin Cancer Res. 4, 1873-1880.