The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck

Journal of Virology

Volumn 75, Issue 19, 2001, Pages 9378-9392

  Hanna, Z ^a   Weng, X ^a   Kay, D G ^a   Poudrier, J ^a   Lowell, C ^a   Jolicoeur, P ^a  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; HEMATOPOIETIC CELL KINASE; NEF PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL CELL; ARTICLE; BREEDING; GENE MUTATION; HUMAN IMMUNODEFICIENCY VIRUS 1; LIGAND BINDING; MOUSE; NONHUMAN; PATHOGENICITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; T LYMPHOCYTE SUBPOPULATION; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, CD4; GENES, NEF; HIV INFECTIONS; HIV-1; HUMANS; MICE; MICE, TRANSGENIC; MUTATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-HCK; SRC HOMOLOGY DOMAINS; VIRULENCE; VIRUS REPLICATION;

EID: 0034843329     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.19.9378-9392.2001     Document Type: Article

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