메뉴 건너뛰기




Volumn 6, Issue 3, 1997, Pages 283-291

The N-terminus of Nef from HIV-1/SIV associates with a protein complex containing Lck and a serine kinase

Author keywords

[No Author keywords available]

Indexed keywords

NEF PROTEIN; PROTEIN SERINE KINASE;

EID: 0030887932     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80331-3     Document Type: Article
Times cited : (141)

References (36)
  • 1
    • 0028180868 scopus 로고
    • Nef induces CD4 endocytosis: Requirement for acritical dileucine motif in the membrane-proximal CD4 cytoplasmic domain
    • Aiken, C., Konner, J., Landau, N.B., Lenburg, M.E., and Trono, D. (1994). Nef induces CD4 endocytosis: requirement for acritical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell 76, 853-864.
    • (1994) Cell , vol.76 , pp. 853-864
    • Aiken, C.1    Konner, J.2    Landau, N.B.3    Lenburg, M.E.4    Trono, D.5
  • 2
    • 0028485232 scopus 로고
    • HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization
    • Baur, A.S., Sawai, E.T., Dazin, P., Fantl, W.J., Cheng Mayer, C., and Peterlin, B.M. (1994). HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization. Immunity 1, 373-384.
    • (1994) Immunity , vol.1 , pp. 373-384
    • Baur, A.S.1    Sawai, E.T.2    Dazin, P.3    Fantl, W.J.4    Cheng Mayer, C.5    Peterlin, B.M.6
  • 4
    • 0029021821 scopus 로고
    • In vitro binding and phosphorylation of human immunodeficiency virus type 1 Nef protein by serine/threonine protein kinase
    • Bodeus, M., Marie-Cardine, A., Bougeret, C., Ramos-Morales, F., and Benarous, R. (1995). In vitro binding and phosphorylation of human immunodeficiency virus type 1 Nef protein by serine/threonine protein kinase. J. Gen. Virol. 76, 1337-1344.
    • (1995) J. Gen. Virol. , vol.76 , pp. 1337-1344
    • Bodeus, M.1    Marie-Cardine, A.2    Bougeret, C.3    Ramos-Morales, F.4    Benarous, R.5
  • 6
    • 0028302998 scopus 로고
    • Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene
    • Chowers, M.Y., Spina, C.A., Kwoh, T.J., Fitch, N.J., Richman, D.D., and Guatelli, J.C. (1994). Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene. J. Virol. 68, 2906-2914.
    • (1994) J. Virol. , vol.68 , pp. 2906-2914
    • Chowers, M.Y.1    Spina, C.A.2    Kwoh, T.J.3    Fitch, N.J.4    Richman, D.D.5    Guatelli, J.C.6
  • 8
    • 0020983488 scopus 로고
    • Detection and quantitation of phosphotyrosine in proteins
    • Cooper, J.A., Sefton, B.M., and Hunter, T. (1983). Detection and quantitation of phosphotyrosine in proteins. Meth. Enzymol. 99, 387-405.
    • (1983) Meth. Enzymol. , vol.99 , pp. 387-405
    • Cooper, J.A.1    Sefton, B.M.2    Hunter, T.3
  • 9
    • 0001888446 scopus 로고
    • Regulation of HIV gene expression
    • Cullen, B.R. (1995). Regulation of HIV gene expression. AIDS 9 (suppl. A), 19-32.
    • (1995) AIDS , vol.9 , Issue.SUPPL. A , pp. 19-32
    • Cullen, B.R.1
  • 12
    • 0028258948 scopus 로고
    • Stability and proteolytic domains of Nef protein from human immunodeficiency virus (HIV) type 1
    • Freund, J., Kellner, R., Houthaeve, T., and Kalbitzer, H.R. (1994a). Stability and proteolytic domains of Nef protein from human immunodeficiency virus (HIV) type 1. Eur. J. Biochem. 221, 811-819.
    • (1994) Eur. J. Biochem. , vol.221 , pp. 811-819
    • Freund, J.1    Kellner, R.2    Houthaeve, T.3    Kalbitzer, H.R.4
  • 13
    • 0027999147 scopus 로고
    • A possible regulation of negative factor (Nef) activity of human immunodeficiency virus type 1 by the viral protease
    • Freund, J., Kellner, R., Konvalinka, J., Wolber, V., Kräusslich, H.G., and Kalbitzer, H.R. (1994b). A possible regulation of negative factor (Nef) activity of human immunodeficiency virus type 1 by the viral protease. FEBS Lett. 223, 589-593.
    • (1994) FEBS Lett. , vol.223 , pp. 589-593
    • Freund, J.1    Kellner, R.2    Konvalinka, J.3    Wolber, V.4    Kräusslich, H.G.5    Kalbitzer, H.R.6
  • 14
    • 0028839344 scopus 로고
    • HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase
    • Gallay, P., Swingler, S., Song, J., Bushman, F., and Trono, D. (1995). HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase. Cell 83, 569-576.
    • (1995) Cell , vol.83 , pp. 569-576
    • Gallay, P.1    Swingler, S.2    Song, J.3    Bushman, F.4    Trono, D.5
  • 15
    • 0027450321 scopus 로고
    • The negative effect of human immunodeficiency virus type 1 Nef on cell surface CD4 expression is not species specific and requires the cytoplasmic domain of CD4
    • Garcia, J.V., Alfano, J., and Miller, A.D. (1993). The negative effect of human immunodeficiency virus type 1 Nef on cell surface CD4 expression is not species specific and requires the cytoplasmic domain of CD4. J. Virol. 67, 1511-1516.
    • (1993) J. Virol. , vol.67 , pp. 1511-1516
    • Garcia, J.V.1    Alfano, J.2    Miller, A.D.3
  • 16
    • 0029046227 scopus 로고
    • Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef
    • Goldsmith, M.A., Warmerdam, M.T., Atchinson, R.E., Miller, M.D., and Greene, W.C. (1995). Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef. J. Virol. 69, 4112-4121.
    • (1995) J. Virol. , vol.69 , pp. 4112-4121
    • Goldsmith, M.A.1    Warmerdam, M.T.2    Atchinson, R.E.3    Miller, M.D.4    Greene, W.C.5
  • 17
    • 0028887886 scopus 로고
    • Human immunodeficiency virus type 1 Nef protein inhibits activation pathways in peripheral blood mononuclear cells and T-cell lines
    • Greenway, A., Azad, A., and McPhee, D. (1995). Human immunodeficiency virus type 1 Nef protein inhibits activation pathways in peripheral blood mononuclear cells and T-cell lines. J. Virol. 69, 1842-1850.
    • (1995) J. Virol. , vol.69 , pp. 1842-1850
    • Greenway, A.1    Azad, A.2    McPhee, D.3
  • 18
    • 0029795040 scopus 로고    scopus 로고
    • The CD4 determinant for downregulation by HIV-1 Nef directly binds Nef: Mapping of the Nef binding surface by NMR
    • Grzesiek, S., Stahl, S.J., Wingfield, P.T., and Bax, A. (1996). The CD4 determinant for downregulation by HIV-1 Nef directly binds Nef: mapping of the Nef binding surface by NMR. Biochemistry 35, 10256-10261.
    • (1996) Biochemistry , vol.35 , pp. 10256-10261
    • Grzesiek, S.1    Stahl, S.J.2    Wingfield, P.T.3    Bax, A.4
  • 19
    • 0026605537 scopus 로고
    • CLUSTAL V: Improved software for multiple sequence alignments
    • Higgins, D.G., Bleasby, A.J., and Fuchs, R. (1992). CLUSTAL V: improved software for multiple sequence alignments. Comput. Appl. Biosci. 8, 189-191.
    • (1992) Comput. Appl. Biosci. , vol.8 , pp. 189-191
    • Higgins, D.G.1    Bleasby, A.J.2    Fuchs, R.3
  • 21
    • 0028835788 scopus 로고
    • Brief report: Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection
    • Kirchhoff, F., Greenough, T.C., Brettler, D.B., Sullivan, J.L., and Desrosiers, R.C. (1995). Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection. N. Engl. J. Med. 332, 228-232.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 228-232
    • Kirchhoff, F.1    Greenough, T.C.2    Brettler, D.B.3    Sullivan, J.L.4    Desrosiers, R.C.5
  • 22
    • 0343494918 scopus 로고    scopus 로고
    • Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain
    • Lee, C.H., Saksela, K., Mirza, U.A., Chait, B.T., and Kuriyan, J. (1996). Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain. Cell 85, 931-942.
    • (1996) Cell , vol.85 , pp. 931-942
    • Lee, C.H.1    Saksela, K.2    Mirza, U.A.3    Chait, B.T.4    Kuriyan, J.5
  • 23
    • 0030475891 scopus 로고    scopus 로고
    • CDC42 and Rac1 are implicated in the activation of the Net-associated kinase and replication of HIV-1
    • Lu, X., Wu, X., Plemenitas, A., Yu, H., Sawai, E.T., Abo, A., and Peterlin, B.M. (1996). CDC42 and Rac1 are implicated in the activation of the Net-associated kinase and replication of HIV-1. Curr. Biol. 6, 1677-1684.
    • (1996) Curr. Biol. , vol.6 , pp. 1677-1684
    • Lu, X.1    Wu, X.2    Plemenitas, A.3    Yu, H.4    Sawai, E.T.5    Abo, A.6    Peterlin, B.M.7
  • 24
    • 0026077650 scopus 로고
    • Expression of the type 1 human immunodeficiency virus Nef protein in T cells prevents antigen receptor-mediated induction of interleukin 2 mRNA
    • Luria, S., Chambers, I., and Berg, P. (1991). Expression of the type 1 human immunodeficiency virus Nef protein in T cells prevents antigen receptor-mediated induction of interleukin 2 mRNA. Proc. Natl. Acad. Sci. USA 88, 5326-5330.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5326-5330
    • Luria, S.1    Chambers, I.2    Berg, P.3
  • 25
    • 0028006247 scopus 로고
    • The human immunodeficiency virus-1 nef gene product: A positive factor for viral infection and replication in primary lymphocytes and macrophages
    • Miller, M.D., Warmerdam, M.T., Gaston, I., Greene, W.C., and Feinberg, M.B. (1994). The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. J. Exp. Med. 179, 101-113.
    • (1994) J. Exp. Med. , vol.179 , pp. 101-113
    • Miller, M.D.1    Warmerdam, M.T.2    Gaston, I.3    Greene, W.C.4    Feinberg, M.B.5
  • 26
    • 0026674005 scopus 로고
    • Human immunodeficiency virus type 1 Nef protein inhibits NF-κB induction in human T cells
    • Niederman, T.M., Garcia, J.V., Hastings, W.R., Luria, S., and Ratner, L. (1992). Human immunodeficiency virus type 1 Nef protein inhibits NF-κB induction in human T cells. J. Virol. 66, 6213-6219.
    • (1992) J. Virol. , vol.66 , pp. 6213-6219
    • Niederman, T.M.1    Garcia, J.V.2    Hastings, W.R.3    Luria, S.4    Ratner, L.5
  • 27
    • 0028200761 scopus 로고
    • Human immunodeficiency virus type 1 Net-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4
    • Rhee, S.S., and Marsh, J.W. (1994). Human immunodeficiency virus type 1 Net-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4. J. Virol. 68, 5156-5163.
    • (1994) J. Virol. , vol.68 , pp. 5156-5163
    • Rhee, S.S.1    Marsh, J.W.2
  • 28
    • 0027291015 scopus 로고
    • Prediction of protein structure at better than 70% accuracy
    • Rost, B., and Sander, C. (1993). Prediction of protein structure at better than 70% accuracy. J. Mol. Biol. 232, 584-599.
    • (1993) J. Mol. Biol. , vol.232 , pp. 584-599
    • Rost, B.1    Sander, C.2
  • 29
    • 0028878783 scopus 로고
    • Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4
    • Saksela, K., Cheng, G., and Baltimore, D. (1995). Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4. EMBO J. 14, 484-491.
    • (1995) EMBO J. , vol.14 , pp. 484-491
    • Saksela, K.1    Cheng, G.2    Baltimore, D.3
  • 30
  • 31
    • 0029064101 scopus 로고
    • A highly conserved region and membrane targeting of Nef from primate immunodeficiency viruses are required for association with a cellular serine kinase activity
    • Sawai, E.T., Baur, A.S., Peterlin, B.M., Levy, J.A., and Cheng-Mayer, C. (1995). A highly conserved region and membrane targeting of Nef from primate immunodeficiency viruses are required for association with a cellular serine kinase activity. J. Biol. Chem. 270, 15307-15314.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15307-15314
    • Sawai, E.T.1    Baur, A.S.2    Peterlin, B.M.3    Levy, J.A.4    Cheng-Mayer, C.5
  • 32
    • 0027952787 scopus 로고
    • The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes
    • Spina, C.A., Kwoh, T.J., Chowers, M.Y., Guatelli, J.C., and Richman, D.D. (1994). The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes. J. Exp. Med. 179, 115-123.
    • (1994) J. Exp. Med. , vol.179 , pp. 115-123
    • Spina, C.A.1    Kwoh, T.J.2    Chowers, M.Y.3    Guatelli, J.C.4    Richman, D.D.5
  • 33
    • 0026705903 scopus 로고
    • Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor
    • Straus, D.B., and Weiss, A. (1992). Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell 70, 585-593.
    • (1992) Cell , vol.70 , pp. 585-593
    • Straus, D.B.1    Weiss, A.2
  • 34
    • 0028116642 scopus 로고
    • Molecular biology of the human immunodeficiency virus accessory proteins
    • Subbramanian, R.A., and Cohen, E.A. (1994). Molecular biology of the human immunodeficiency virus accessory proteins. J. Virol. 68, 6831-6835.
    • (1994) J. Virol. , vol.68 , pp. 6831-6835
    • Subbramanian, R.A.1    Cohen, E.A.2
  • 35
    • 0029150052 scopus 로고
    • HIV accessory proteins: Leading roles for the supporting cast
    • Trono, D. (1995). HIV accessory proteins: leading roles for the supporting cast. Cell 82, 189-192.
    • (1995) Cell , vol.82 , pp. 189-192
    • Trono, D.1
  • 36
    • 0027237785 scopus 로고
    • Effect of nef alleles on replication of human immunodeficiency virus type 1
    • Zazopoulos, E., and Haseltine, W.A. (1993). Effect of nef alleles on replication of human immunodeficiency virus type 1. Virology 194, 20-27.
    • (1993) Virology , vol.194 , pp. 20-27
    • Zazopoulos, E.1    Haseltine, W.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.