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Volumn 72, Issue 7, 1998, Pages 5820-5830

Role of the SH3-ligand domain of simian immunodeficiency virus Nef in interaction with Nef-associated kinase and simian aids in rhesus macaques

Author keywords

[No Author keywords available]

Indexed keywords

NEF ASSOCIATED KINASE; NEF PROTEIN; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

EID: 0031777959     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.7.5820-5830.1998     Document Type: Article
Times cited : (69)

References (56)
  • 1
    • 0030788298 scopus 로고    scopus 로고
    • A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 Nef alleles in lymphocyte activation
    • Alexander, L., Z. Du, M. Rosenzweig, J. U. Jung, and R. C. Desrosiers. 1997. A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 Nef alleles in lymphocyte activation. J. Virol. 71:6094-6099.
    • (1997) J. Virol. , vol.71 , pp. 6094-6099
    • Alexander, L.1    Du, Z.2    Rosenzweig, M.3    Jung, J.U.4    Desrosiers, R.C.5
  • 2
    • 0028915798 scopus 로고
    • Proline-rich sequences that bind to Src homology 3 domains with individual specificities
    • Alexandropoulos, K., G. Cheng, and D. Baltimore. 1995. Proline-rich sequences that bind to Src homology 3 domains with individual specificities. Proc. Natl. Acad. Sci. USA 92:3110-3114.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3110-3114
    • Alexandropoulos, K.1    Cheng, G.2    Baltimore, D.3
  • 3
    • 2642676749 scopus 로고    scopus 로고
    • Human immunodeficiency virus-related infections in animal models
    • V. T. Devita, S. Hellman, and S. A. Rosenberg (ed.), Lippincott-Raven, Philadelphia, Pa
    • Allan, J. S. 1997. Human immunodeficiency virus-related infections in animal models, p. 15-27. In V. T. Devita, S. Hellman, and S. A. Rosenberg (ed.), AIDS - etiology, diagnosis, treatment and prevention. Lippincott-Raven, Philadelphia, Pa.
    • (1997) AIDS - Etiology, Diagnosis, Treatment and Prevention , pp. 15-27
    • Allan, J.S.1
  • 4
    • 0028944667 scopus 로고
    • Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques
    • Baba, T. W., Y. S. Jeong, D. Pennick, R. Bronson, M. F. Greene, and R. M. Ruprecht. 1995. Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques. Science 267:1820-1825.
    • (1995) Science , vol.267 , pp. 1820-1825
    • Baba, T.W.1    Jeong, Y.S.2    Pennick, D.3    Bronson, R.4    Greene, M.F.5    Ruprecht, R.M.6
  • 5
    • 0025818336 scopus 로고
    • In vitro macrophage tropism of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac)
    • Banapour, B., M. L. Marthas, R. J. Munn, and P. A. Luciw. 1991. In vitro macrophage tropism of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac). Virology 183:12-19.
    • (1991) Virology , vol.183 , pp. 12-19
    • Banapour, B.1    Marthas, M.L.2    Munn, R.J.3    Luciw, P.A.4
  • 6
    • 0028485232 scopus 로고
    • HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization
    • Baur, A. S., E. T. Sawai, P. Dazin, W. J. Fantl, C. Cheng-Mayer, and B. M. Peterlin. 1994. HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization. Immunity 1:373-384.
    • (1994) Immunity , vol.1 , pp. 373-384
    • Baur, A.S.1    Sawai, E.T.2    Dazin, P.3    Fantl, W.J.4    Cheng-Mayer, C.5    Peterlin, B.M.6
  • 7
    • 0030025111 scopus 로고    scopus 로고
    • Immune dysregulation in Ethiopian immigrants in Israel: Relevance to helminth infections?
    • Bentwich, Z., Z. Weisman, C. Moroz, S. Bar-Yehuda, and A. Kalinkovich. 1996. Immune dysregulation in Ethiopian immigrants in Israel: relevance to helminth infections? Clin. Exp. Immunol. 103:239-243.
    • (1996) Clin. Exp. Immunol. , vol.103 , pp. 239-243
    • Bentwich, Z.1    Weisman, Z.2    Moroz, C.3    Bar-Yehuda, S.4    Kalinkovich, A.5
  • 8
    • 0028173343 scopus 로고
    • The role of Nef in the replication cycle of the human and simian immunodeficiency viruses
    • Cullen, B. R. 1994. The role of Nef in the replication cycle of the human and simian immunodeficiency viruses. Virology 205:1-6.
    • (1994) Virology , vol.205 , pp. 1-6
    • Cullen, B.R.1
  • 11
    • 0027962645 scopus 로고
    • Two binding orientations for peptides to the Src SH3 domain development of a general model for SH3-ligand interactions
    • Feng, S., J. K. Chen, H. Yu, J. A. Simon, and S. L. Schreiber. 1994. Two binding orientations for peptides to the Src SH3 domain development of a general model for SH3-ligand interactions. Science 266:1241-1247.
    • (1994) Science , vol.266 , pp. 1241-1247
    • Feng, S.1    Chen, J.K.2    Yu, H.3    Simon, J.A.4    Schreiber, S.L.5
  • 12
    • 0024334683 scopus 로고
    • Identification and biologic characterization of an acutely lethal variant of simian immunodeficiency virus from sooty mangabeys (SIV/SMM)
    • Fultz P. N., H. M. McClure, D. C. Anderson, and W. M. Switzer. 1989. Identification and biologic characterization of an acutely lethal variant of simian immunodeficiency virus from sooty mangabeys (SIV/SMM). AIDS Res Hum. Retroviruses 5:397-409.
    • (1989) AIDS Res Hum. Retroviruses , vol.5 , pp. 397-409
    • Fultz, P.N.1    McClure, H.M.2    Anderson, D.C.3    Switzer, W.M.4
  • 13
    • 0029830139 scopus 로고    scopus 로고
    • The acaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1
    • Galisteo, M. L., J. Chernoff, Y.-C. Su, E. Y. Skolnick, and J. Schlessinger. 1996. The acaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1. J. Biol. Chem. 271:20997-21000.
    • (1996) J. Biol. Chem. , vol.271 , pp. 20997-21000
    • Galisteo, M.L.1    Chernoff, J.2    Su, Y.-C.3    Skolnick, E.Y.4    Schlessinger, J.5
  • 14
    • 0029046227 scopus 로고
    • Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef
    • Goldsmith, M. A., M. T. Warmerdam, R. E. Archison, M. D. Miller, and W. C. Greene. 1995. Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef. J. Virol. 69:4112-4121.
    • (1995) J. Virol. , vol.69 , pp. 4112-4121
    • Goldsmith, M.A.1    Warmerdam, M.T.2    Archison, R.E.3    Miller, M.D.4    Greene, W.C.5
  • 15
    • 0029881450 scopus 로고    scopus 로고
    • The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase
    • Grzesiek, S., A. Bax, G. M. Clore, A. M. Gronenborn, S. J. Hu, J. Kaufman, I. Palmer, S. J. Stahl, and P. T. Wingfield. 1996. The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase. Nat. Struct. Biol. 3:340-345.
    • (1996) Nat. Struct. Biol. , vol.3 , pp. 340-345
    • Grzesiek, S.1    Bax, A.2    Clore, G.M.3    Gronenborn, A.M.4    Hu, S.J.5    Kaufman, J.6    Palmer, I.7    Stahl, S.J.8    Wingfield, P.T.9
  • 16
    • 0031039979 scopus 로고    scopus 로고
    • Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling
    • Iafrate, J. A., S. Bronson, and J. Skowronski. 1997. Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling. EMBO J. 16:673-684.
    • (1997) EMBO J. , vol.16 , pp. 673-684
    • Iafrate, J.A.1    Bronson, S.2    Skowronski, J.3
  • 17
    • 0023029916 scopus 로고
    • Humoral immune responses to T cell tropic retrovirus simian T lymphotropic virus type II in monkeys with experimentally induced acquired immune deficiency-like syndrome
    • Kannagi, M., M. Kiyotaki, R. C. Desrosiers, K. A. Reimann, N. W. King, L. M. Waldron, and N. L. Letvin. 1986. Humoral immune responses to T cell tropic retrovirus simian T lymphotropic virus type II in monkeys with experimentally induced acquired immune deficiency-like syndrome. J. Clin. Invest. 78:1229-1236.
    • (1986) J. Clin. Invest. , vol.78 , pp. 1229-1236
    • Kannagi, M.1    Kiyotaki, M.2    Desrosiers, R.C.3    Reimann, K.A.4    King, N.W.5    Waldron, L.M.6    Letvin, N.L.7
  • 18
    • 0030338655 scopus 로고    scopus 로고
    • The role of host genetics in the natural history of HIV-1 infection: The needles in the haystack
    • Keet, I. P. M., M. R. Klein, J. J. Just, and R. A. Kaslow. 1996. The role of host genetics in the natural history of HIV-1 infection: the needles in the haystack. AIDS 10:S59-S67.
    • (1996) AIDS , vol.10
    • Keet, I.P.M.1    Klein, M.R.2    Just, J.J.3    Kaslow, R.A.4
  • 19
  • 20
    • 0030836543 scopus 로고    scopus 로고
    • Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques
    • Lang, S. M., A. J. Iafrate, C. Stahl-Hennig, E. M. Kuhn, T. Nisslein, F.-J. Kaup, M. Maupt, G. Hunsmann, J. Skowronski, and F. Kirchoff. 1997. Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques. Nat. Med. 3:860-865.
    • (1997) Nat. Med. , vol.3 , pp. 860-865
    • Lang, S.M.1    Iafrate, A.J.2    Stahl-Hennig, C.3    Kuhn, E.M.4    Nisslein, T.5    Kaup, F.-J.6    Maupt, M.7    Hunsmann, G.8    Skowronski, J.9    Kirchoff, F.10
  • 21
    • 0028805516 scopus 로고
    • A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein
    • Lee, C. H., B. Leung, M. A. Lemmon, J. Zheng, D. Cowburn, J. Kuriyan, and K. Saksela. 1995. A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein. EMBO J. 14: 5006-5015.
    • (1995) EMBO J. , vol.14 , pp. 5006-5015
    • Lee, C.H.1    Leung, B.2    Lemmon, M.A.3    Zheng, J.4    Cowburn, D.5    Kuriyan, J.6    Saksela, K.7
  • 22
    • 0343494918 scopus 로고    scopus 로고
    • Crystal structure of the conserved core of HIV-1 Nef complexed with a src family of SH3 domain
    • Lee, C. H., K. Saksela, U. A. Mirza, B. T. Chait, and J. Kuriyan. 1996. Crystal structure of the conserved core of HIV-1 Nef complexed with a src family of SH3 domain. Cell 85:931-942.
    • (1996) Cell , vol.85 , pp. 931-942
    • Lee, C.H.1    Saksela, K.2    Mirza, U.A.3    Chait, B.T.4    Kuriyan, J.5
  • 23
    • 0028568643 scopus 로고
    • Establishing specific retrovirus-free breeding colonies of macaques: An approach to primary screening and surveillance
    • Lerche, N., J. L. Yee, and M. B. Jennings. 1994. Establishing specific retrovirus-free breeding colonies of macaques: an approach to primary screening and surveillance. Lab. Anim. Sci. 44:217-221.
    • (1994) Lab. Anim. Sci. , vol.44 , pp. 217-221
    • Lerche, N.1    Yee, J.L.2    Jennings, M.B.3
  • 24
    • 0031401409 scopus 로고    scopus 로고
    • Screening for simian type-D retrovirus infection in macaques, using nested polymerase chain reaction
    • Lerche, N. W., R. F. Cotterman, M. D. Dobson, J. L. Yee, A. N. Rosenthal, and W. M. Heneine. 1997. Screening for simian type-D retrovirus infection in macaques, using nested polymerase chain reaction. Lab. Anim. Sci. 47:263-268.
    • (1997) Lab. Anim. Sci. , vol.47 , pp. 263-268
    • Lerche, N.W.1    Cotterman, R.F.2    Dobson, M.D.3    Yee, J.L.4    Rosenthal, A.N.5    Heneine, W.M.6
  • 25
    • 0028148629 scopus 로고
    • Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains
    • Lim, W. A., F. M. Richards, and R. O. Fox. 1994. Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains. Nature 372:375-379.
    • (1994) Nature , vol.372 , pp. 375-379
    • Lim, W.A.1    Richards, F.M.2    Fox, R.O.3
  • 26
    • 0031080595 scopus 로고    scopus 로고
    • Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck
    • Lu, W., S. Katz, R. Gupta, and B. J. Mayer. 1997. Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck. Curr. Biol. 7:85-94.
    • (1997) Curr. Biol. , vol.7 , pp. 85-94
    • Lu, W.1    Katz, S.2    Gupta, R.3    Mayer, B.J.4
  • 27
    • 0030475891 scopus 로고    scopus 로고
    • CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1
    • Lu, X., X. Wu, A. Plemenitas, H. Yu, E. T. Sawai, A. Abo, and B. M. Peterlin. 1996. CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1. Curr. Biol. 6:1677-1684.
    • (1996) Curr. Biol. , vol.6 , pp. 1677-1684
    • Lu, X.1    Wu, X.2    Plemenitas, A.3    Yu, H.4    Sawai, E.T.5    Abo, A.6    Peterlin, B.M.7
  • 28
    • 0030775332 scopus 로고    scopus 로고
    • Activation of the T-cell receptor signaling pathway by Nef from an aggressive strain of simian immunodeficiency virus
    • Luo, W., and B. M. Peterlin. 1997. Activation of the T-cell receptor signaling pathway by Nef from an aggressive strain of simian immunodeficiency virus. J. Virol. 71:9531-9537.
    • (1997) J. Virol. , vol.71 , pp. 9531-9537
    • Luo, W.1    Peterlin, B.M.2
  • 29
    • 0029846223 scopus 로고    scopus 로고
    • High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection
    • Mariani, R., F. Kirchhoff, T. C. Greenough, J. L. Sullivan, R. C. Desrosiers, and J. Skowronski. 1996. High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection. J. Virol. 70:7752-7764.
    • (1996) J. Virol. , vol.70 , pp. 7752-7764
    • Mariani, R.1    Kirchhoff, F.2    Greenough, T.C.3    Sullivan, J.L.4    Desrosiers, R.C.5    Skowronski, J.6
  • 30
    • 2642646062 scopus 로고    scopus 로고
    • Personal communication
    • Marthas, M. Personal communication.
    • Marthas, M.1
  • 31
    • 0027303677 scopus 로고
    • Viral determinants of simian immunodeficiency virus (SIV) virulence in rhesus macaques assessed by using attenuated and pathogenic molecular clones of SIVmac
    • Marthas, M. L., R. A. Ramos, B. L. Lohman, K. Van Rompay, R. E. Unger, C. J. Miller, B. Banapour, N. C. Pedersen, and P. A. Luciw. 1993. Viral determinants of simian immunodeficiency virus (SIV) virulence in rhesus macaques assessed by using attenuated and pathogenic molecular clones of SIVmac. J. Virol. 67:6047-6055.
    • (1993) J. Virol. , vol.67 , pp. 6047-6055
    • Marthas, M.L.1    Ramos, R.A.2    Lohman, B.L.3    Van Rompay, K.4    Unger, R.E.5    Miller, C.J.6    Banapour, B.7    Pedersen, N.C.8    Luciw, P.A.9
  • 33
    • 0028006247 scopus 로고
    • The human immunodeficiency virus-1 nef gene product: A positive factor for viral infection and replication in primary lymphocytes and macrophages
    • Miller, M. D., M. T. Warmerdam, I. Gaston, W. C. Greene, and M. B. Feinberg. 1994. The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. J. Exp. Med. 179:101-113.
    • (1994) J. Exp. Med. , vol.179 , pp. 101-113
    • Miller, M.D.1    Warmerdam, M.T.2    Gaston, I.3    Greene, W.C.4    Feinberg, M.B.5
  • 36
    • 0029793714 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Nef associates with a member of the p21-activated kinase family
    • Nunn, M. F., and J. W. Marsh. 1996. Human immunodeficiency virus type 1 Nef associates with a member of the p21-activated kinase family. J. Virol. 70: 6157-6161.
    • (1996) J. Virol. , vol.70 , pp. 6157-6161
    • Nunn, M.F.1    Marsh, J.W.2
  • 38
    • 2642641975 scopus 로고    scopus 로고
    • Planelles, V., and P. A. Luciw. Unpublished data
    • Planelles, V., and P. A. Luciw. Unpublished data.
  • 40
    • 33745158157 scopus 로고
    • A simple method of estimating fifty percent endpoints
    • Reed, L. J., and H. Muench. 1938. A simple method of estimating fifty percent endpoints. Am. J. Hyg. 27:493-497.
    • (1938) Am. J. Hyg. , vol.27 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 41
    • 0030330585 scopus 로고    scopus 로고
    • Murine and simian retrovirus models: The threshold hypothesis
    • Ruprecht, R. M., T. W. Baba, R. Rasmussen, Y. Hu, and P. L. Sharma. 1996. Murine and simian retrovirus models: the threshold hypothesis. AIDS 10: S33-S40.
    • (1996) AIDS , vol.10
    • Ruprecht, R.M.1    Baba, T.W.2    Rasmussen, R.3    Hu, Y.4    Sharma, P.L.5
  • 42
    • 0002499409 scopus 로고    scopus 로고
    • Clinical spectrum of human immunodeficiency virus diseases
    • V. T. Devita, S. Hellman, and S. A. Rosenberg (ed.), Lippincott-Raven, Philadelphia, Pa
    • Saag, M. S. 1997. Clinical spectrum of human immunodeficiency virus diseases, p. 203-213. In V. T. Devita, S. Hellman, and S. A. Rosenberg (ed.), AIDS - etiology, diagnosis, treatment and prevention. Lippincott-Raven, Philadelphia, Pa.
    • (1997) AIDS - Etiology, Diagnosis, Treatment and Prevention , pp. 203-213
    • Saag, M.S.1
  • 43
    • 0001530806 scopus 로고    scopus 로고
    • HIV-1 Nef and host cell protein kinases
    • Saksela, K. 1997. HIV-1 Nef and host cell protein kinases. Front. Biol. 2: 606-618.
    • (1997) Front. Biol. , vol.2 , pp. 606-618
    • Saksela, K.1
  • 44
    • 0028878783 scopus 로고
    • Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4
    • Saksela, K., G. Cheng, and D. Baltimore. 1995. Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4. EMBO J. 14:484-491.
    • (1995) EMBO J. , vol.14 , pp. 484-491
    • Saksela, K.1    Cheng, G.2    Baltimore, D.3
  • 46
    • 0029064101 scopus 로고
    • A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity
    • Sawai, E. T., A. S. Baur, B. M. Peterlin, J. A. Levy, and C. Cheng-Mayer. 1995. A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity. J. Biol. Chem. 270:15307-15314.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15307-15314
    • Sawai, E.T.1    Baur, A.S.2    Peterlin, B.M.3    Levy, J.A.4    Cheng-Mayer, C.5
  • 49
    • 0027533215 scopus 로고
    • Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene
    • Skowronski, J., D. Parks, and R. Mariani. 1993. Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene. EMBO J. 12: 703-713.
    • (1993) EMBO J. , vol.12 , pp. 703-713
    • Skowronski, J.1    Parks, D.2    Mariani, R.3
  • 50
    • 0029150052 scopus 로고
    • HIV accessory proteins: Leading roles for the supporting cast
    • Trono, D. 1995. HIV accessory proteins: leading roles for the supporting cast. Cell 82:189-192.
    • (1995) Cell , vol.82 , pp. 189-192
    • Trono, D.1
  • 52
    • 0030273317 scopus 로고    scopus 로고
    • HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficiency of proviral DNA synthesis
    • Wiskerchen, M., and C. Cheng-Mayer. 1997. HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficiency of proviral DNA synthesis. Virology 224:292-301.
    • (1997) Virology , vol.224 , pp. 292-301
    • Wiskerchen, M.1    Cheng-Mayer, C.2
  • 53
    • 0031026713 scopus 로고    scopus 로고
    • Resistance of neonatal monkeys to live attenuated vaccine strains of simian immunodeficiency virus
    • Wyand, M. S., K. H. Manson, A. A. Lackner, and R. C. Desrosiers. 1997. Resistance of neonatal monkeys to live attenuated vaccine strains of simian immunodeficiency virus. Nat. Med. 3:32-36.
    • (1997) Nat. Med. , vol.3 , pp. 32-36
    • Wyand, M.S.1    Manson, K.H.2    Lackner, A.A.3    Desrosiers, R.C.4
  • 54
    • 0031025991 scopus 로고    scopus 로고
    • Three-dimensional structure of the tyrosine kinase c-Src
    • Xu, W., S. C. Harrison, and M. J. Eck. 1997. Three-dimensional structure of the tyrosine kinase c-Src. Nature 385:595-602.
    • (1997) Nature , vol.385 , pp. 595-602
    • Xu, W.1    Harrison, S.C.2    Eck, M.J.3
  • 55
    • 0024247071 scopus 로고
    • Relationship of antibody responses and viral antigenemia to SIV/Delta-induce immunodeficiency disease in rhesus macaques
    • Zhang, J., L. N. Martin, E. A. Watson, R. Montelaro, M. West, L. Epstein, and M. Murphey-Corb. 1988. Relationship of antibody responses and viral antigenemia to SIV/Delta-induce immunodeficiency disease in rhesus macaques. J. Infect. Dis. 158:1277-1286.
    • (1988) J. Infect. Dis. , vol.158 , pp. 1277-1286
    • Zhang, J.1    Martin, L.N.2    Watson, E.A.3    Montelaro, R.4    West, M.5    Epstein, L.6    Murphey-Corb, M.7
  • 56
    • 0002925551 scopus 로고
    • Immunity to viruses
    • W. E. Paul (ed.), Raven Press, New York, N.Y.
    • Zinkernagel, R. M. 1993. Immunity to viruses, p. 1211-1250. In W. E. Paul (ed.), Fundamental immunology. Raven Press, New York, N.Y.
    • (1993) Fundamental Immunology , pp. 1211-1250
    • Zinkernagel, R.M.1


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