Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling

EMBO Journal

Volumn 16, Issue 4, 1997, Pages 673-684

  Iafrate, A John ^b   Bronson, Scott ^a   Skowronski, Jacek ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

CD4; Nef; T cell activation; T cell receptor

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; NEF PROTEIN; T LYMPHOCYTE RECEPTOR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CELLULAR IMMUNITY; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; RECEPTOR BLOCKING; SIMIAN IMMUNODEFICIENCY VIRUS; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD; ANTIGENS, CD3; ANTIGENS, CD4; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; COS CELLS; DNA-BINDING PROTEINS; GENE EXPRESSION; GENE PRODUCTS, NEF; HIV-1; HUMANS; JURKAT CELLS; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHOPROTEINS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SIMIAN IMMUNODEFICIENCY VIRUS; TRANSCRIPTION FACTORS, TFII;

EID: 0031039979     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.4.673     Document Type: Article

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