A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFκB in human endothelial cells

Journal of Biological Chemistry

Volumn 275, Issue 20, 2000, Pages 15458-15465

  Madge, Lisa A ^a   Pober, Jordan S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; MITOGEN ACTIVATED PROTEIN KINASE; NUCLEAR FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; TUMOR NECROSIS FACTOR; WORTMANNIN;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INFLAMMATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REPORTER GENE; TRANSCRIPTION REGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; APOPTOSIS; CELLS, CULTURED; CHROMONES; CULTURE MEDIA, SERUM-FREE; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; INTERLEUKIN-1; KINETICS; MORPHOLINES; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; TUMOR NECROSIS FACTOR-ALPHA; UMBILICAL VEINS;

EID: 0034685915     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M001237200     Document Type: Article

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