A novel pathway for tumor necrosis factor-α and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase

Journal of Biological Chemistry

Volumn 274, Issue 18, 1999, Pages 12722-12729

  Hanna, Atef N ^a   Chan, Edmond Y W ^a   Xu, James ^a   Stone, James C ^a   Brindley, David N ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b ALBERTA ENVIRONMENT AND PARKS   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; CERAMIDE; DNA; GENISTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P21; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL LINE; CERAMIDES; ENZYME ACTIVATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS P21(RAS); RATS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0033617315     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.18.12722     Document Type: Article

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