Regulation of Raf-1 kinase by TNF via its second messenger ceramide and cross-talk with mitogenic signalling

EMBO Journal

Volumn 17, Issue 3, 1998, Pages 732-742

  Müller, Gertraud ^a   Storz, Peter ^a   Bourteele, Soizic ^a   Döppler, Heike ^a   Pfizenmaier, Klaus ^a   Mischak, Harald ^b   Philipp, Alex ^b   Kaiser, Christian ^b   Kolch, Walter ^c  

^a UNIVERSITY OF STUTTGART   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

Ceramide; Epidermal growth factor; Raf 1 kinase; Ras; Tumour necrosis factor

Indexed keywords

CERAMIDE; EPIDERMAL GROWTH FACTOR; PROTEIN KINASE; RAF PROTEIN; RAS PROTEIN; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; RHABDOMYOSARCOMA; SECOND MESSENGER; SIGNAL TRANSDUCTION;

3T3 CELLS; ANIMALS; BINDING SITES; CARBON RADIOISOTOPES; CELLS, CULTURED; CERAMIDES; COS CELLS; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; GUANOSINE TRIPHOSPHATE; HELA CELLS; HUMANS; MAP KINASE KINASE 1; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGENS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-RAF; RAS PROTEINS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; INSECTA; MAMMALIA;

EID: 0040885889     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.3.732     Document Type: Article

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