-
1
-
-
0025201426
-
Purification and characterization of phosphoinositide 3-kinase from rat liver
-
Carpenter CL, Duckworth BC, Auger KR, Cohen B, Schaffhausen BS, Cantley LC: Purification and characterization of phosphoinositide 3-kinase from rat liver. J Biol Chem 1990, 265: 19704-19711.
-
(1990)
J Biol Chem
, vol.265
, pp. 19704-19711
-
-
Carpenter, C.L.1
Duckworth, B.C.2
Auger, K.R.3
Cohen, B.4
Schaffhausen, B.S.5
Cantley, L.C.6
-
2
-
-
0026720350
-
Phosphatidylinositol 3-kinase: Structure and expression of the 110 kd catalytic subunit
-
Hiles ID, Otsu M, Volinia S, Fry MJ, Gout I, Dhand R, Panayotou G, Ruiz-Larrea F, Thompson A, Totty NF et al.: Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit. Cell 1992, 70:419-429.
-
(1992)
Cell
, vol.70
, pp. 419-429
-
-
Hiles, I.D.1
Otsu, M.2
Volinia, S.3
Fry, M.J.4
Gout, I.5
Dhand, R.6
Panayotou, G.7
Ruiz-Larrea, F.8
Thompson, A.9
Totty, N.F.10
-
3
-
-
0027905021
-
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting
-
Schu PV, Takegawa K, Fry MJ, Stack JH, Waterfield MD, Emr SD: Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science 1993, 260:88-91.
-
(1993)
Science
, vol.260
, pp. 88-91
-
-
Schu, P.V.1
Takegawa, K.2
Fry, M.J.3
Stack, J.H.4
Waterfield, M.D.5
Emr, S.D.6
-
4
-
-
0028981018
-
A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system
-
Volinia S, Dhand R, Vanhaesebroeck B, MacDougall LK, Stein R, Zvelebil MJ, Domin J, Panaretou C, Waterfield MD: A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system. EMBO J 1995, 14:3339-3348.
-
(1995)
EMBO J
, vol.14
, pp. 3339-3348
-
-
Volinia, S.1
Dhand, R.2
Vanhaesebroeck, B.3
MacDougall, L.K.4
Stein, R.5
Zvelebil, M.J.6
Domin, J.7
Panaretou, C.8
Waterfield, M.D.9
-
5
-
-
0029090212
-
Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase
-
Stoyanov B, Volinia S, Hanck T, Rubio I, Loubtchenkov M, Malek D, Stoyanova S, Vanhaesebroeck B, Dhand R, Nurnberg B et al.: Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase. Science 1995, 269:690-693. This paper describes the cDNA cloning and characteristics of a PI kinase that is activated by both a and β/γ subunits of the G protein transducin.
-
(1995)
Science
, vol.269
, pp. 690-693
-
-
Stoyanov, B.1
Volinia, S.2
Hanck, T.3
Rubio, I.4
Loubtchenkov, M.5
Malek, D.6
Stoyanova, S.7
Vanhaesebroeck, B.8
Dhand, R.9
Nurnberg, B.10
-
6
-
-
0027450410
-
A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity
-
Carpenter CL, Auger KR, Duckworth BC, Hou WM, Schaffhausen B, Cantley LC: A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity. Mol Cell Biol 1993, 13:1657-1665.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 1657-1665
-
-
Carpenter, C.L.1
Auger, K.R.2
Duckworth, B.C.3
Hou, W.M.4
Schaffhausen, B.5
Cantley, L.C.6
-
7
-
-
0027953284
-
PI 3-kinase is a dual specificity enzyme: Autoregulation by an intrinsic protein-serine kinase activity
-
Dhand R, Hiles I, Panayotou G, Roche S, Fry MJ, Gout I, Totty NF, Truong O, Vicendo P, Yonezawa K et al.: PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity. EMBO J 1994, 13:522-533.
-
(1994)
EMBO J
, vol.13
, pp. 522-533
-
-
Dhand, R.1
Hiles, I.2
Panayotou, G.3
Roche, S.4
Fry, M.J.5
Gout, I.6
Totty, N.F.7
Truong, O.8
Vicendo, P.9
Yonezawa, K.10
-
8
-
-
0028110018
-
Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities
-
Stack JH, Emr SD: Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities. J Biol Chem 1994, 269:31552-31562.
-
(1994)
J Biol Chem
, vol.269
, pp. 31552-31562
-
-
Stack, J.H.1
Emr, S.D.2
-
9
-
-
0027768699
-
Phosphatidylinositol 4-kinase: Gene structure and requirement for yeast cell viability
-
Flanagan CA, Schnieders EA, Emerick AW, Kunisawa R, Admon A, Thorner J: Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability. Science 1993, 262:1444-1448.
-
(1993)
Science
, vol.262
, pp. 1444-1448
-
-
Flanagan, C.A.1
Schnieders, E.A.2
Emerick, A.W.3
Kunisawa, R.4
Admon, A.5
Thorner, J.6
-
10
-
-
0027979837
-
A novel gene, STT4, encodes a phosphatidylinositol 4-kinase in the PKC1 protein kinase pathway of Saccharomyces cerevisiae
-
Yoshida S, Ohya Y, Goebl M, Nakano A, Anraku Y: A novel gene, STT4, encodes a phosphatidylinositol 4-kinase in the PKC1 protein kinase pathway of Saccharomyces cerevisiae. J Biol Chem 1994, 269:1166-1172.
-
(1994)
J Biol Chem
, vol.269
, pp. 1166-1172
-
-
Yoshida, S.1
Ohya, Y.2
Goebl, M.3
Nakano, A.4
Anraku, Y.5
-
11
-
-
0028032480
-
Cloning and characterization of a human phosphatidylinositol 4-kinase
-
Wong K, Cantley LC: Cloning and characterization of a human phosphatidylinositol 4-kinase. J Biol Chem 1994, 269:28878-28884.
-
(1994)
J Biol Chem
, vol.269
, pp. 28878-28884
-
-
Wong, K.1
Cantley, L.C.2
-
12
-
-
0028812255
-
The sequence of phosphatidylinositol-4-phosphate 5-kinase defines a novel family of lipid kinases
-
Boronenkov IV, Anderson RA: The sequence of phosphatidylinositol-4-phosphate 5-kinase defines a novel family of lipid kinases. J Biol Chem 1995, 270:2881-2884. The first cDNA clone of a Ptdlns 4-P 5K is described. Surprisingly, it has no homology with other phosphoinositide kinases.
-
(1995)
J Biol Chem
, vol.270
, pp. 2881-2884
-
-
Boronenkov, I.V.1
Anderson, R.A.2
-
13
-
-
0029024442
-
Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast
-
Yamamoto A, DeWald DB, Boronenkov IV, Anderson RA, Emr SD, Koshland D: Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast. Mol Biol Cell 1995, 6:525-539.
-
(1995)
Mol Biol Cell
, vol.6
, pp. 525-539
-
-
Yamamoto, A.1
DeWald, D.B.2
Boronenkov, I.V.3
Anderson, R.A.4
Emr, S.D.5
Koshland, D.6
-
14
-
-
0028856331
-
When is a lipid kinase not a lipid kinase? When it's a protein kinase
-
Hunter T: When is a lipid kinase not a lipid kinase? When it's a protein kinase. Cell 1995, 83:1-4.
-
(1995)
Cell
, vol.83
, pp. 1-4
-
-
Hunter, T.1
-
15
-
-
0029103330
-
Control of p70 S6 kinase by kinase activity of FRAP in vivo
-
Brown EJ, Beal PA, Keith CT, Chen J, Shin TB, Schreiber SL: Control of p70 S6 kinase by kinase activity of FRAP in vivo. Nature 1995, 377:441-446.
-
(1995)
Nature
, vol.377
, pp. 441-446
-
-
Brown, E.J.1
Beal, P.A.2
Keith, C.T.3
Chen, J.4
Shin, T.B.5
Schreiber, S.L.6
-
16
-
-
0029156599
-
DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product
-
Hartley KO, Gell D, Smith GC, Zhang H, Divecha N, Connelly MA, Admon A, Lees-Miller SP, Anderson CW, Jackson SP: DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell 1995, 82:849-856.
-
(1995)
Cell
, vol.82
, pp. 849-856
-
-
Hartley, K.O.1
Gell, D.2
Smith, G.C.3
Zhang, H.4
Divecha, N.5
Connelly, M.A.6
Admon, A.7
Lees-Miller, S.P.8
Anderson, C.W.9
Jackson, S.P.10
-
17
-
-
0029102357
-
The rapamycin and FKBP12 target (RAFT) displays phosphatidylinositol kinase activity
-
Sabatini D, Pierchala B, Barrow R, Schell M, Snyder S: The rapamycin and FKBP12 target (RAFT) displays phosphatidylinositol kinase activity. J Biol Chem 1995, 270:20875-20878.
-
(1995)
J Biol Chem
, vol.270
, pp. 20875-20878
-
-
Sabatini, D.1
Pierchala, B.2
Barrow, R.3
Schell, M.4
Snyder, S.5
-
18
-
-
0028584245
-
The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors
-
Roche S, Koegl M, Courtneidge SA: The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors. Proc Natl Acad Sci USA 1994, 9113:9185-9189.
-
(1994)
Proc Natl Acad Sci USA
, vol.9113
, pp. 9185-9189
-
-
Roche, S.1
Koegl, M.2
Courtneidge, S.A.3
-
19
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez VP, Warne PH, Dhand R, Vanhaesebroeck B, Gout I, Fry MJ, Waterfield MD, Downward J: Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 1994, 370:527-532. This paper reports the association of PI3K with Ras in vitro, and demonstrates an increase in levels of the phosphoinositide products whose synthesis is catalyzed by PI3K in PC12 cells expressing PI3K and dominant-negative V12 Ras. These data place PI3K downstream of Ras.
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez, V.P.1
Warne, P.H.2
Dhand, R.3
Vanhaesebroeck, B.4
Gout, I.5
Fry, M.J.6
Waterfield, M.D.7
Downward, J.8
-
20
-
-
0028918408
-
Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase
-
Hu Q, Klippel A, Muslin AJ, Fantl WJ, Williams LT: Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase. Science 1995, 268:100-102. A constitutively active PI3K induces Fos, and a dominant-negative (N17) Ras and dominant-negative Raf block Fos induction by PI3K. These data place PI3K upstream of Ras.
-
(1995)
Science
, vol.268
, pp. 100-102
-
-
Hu, Q.1
Klippel, A.2
Muslin, A.J.3
Fantl, W.J.4
Williams, L.T.5
-
21
-
-
0028143039
-
Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression
-
Jhun BH, Rose DW, Seely BL, Rameh L, Cantley L, Saltiel AR, Olefsky JM: Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression. Mol Cell Biol 1994, 14:7466-7475.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 7466-7475
-
-
Jhun, B.H.1
Rose, D.W.2
Seely, B.L.3
Rameh, L.4
Cantley, L.5
Saltiel, A.R.6
Olefsky, J.M.7
-
22
-
-
0028963084
-
Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor
-
Yao R, Cooper GM: Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. Science 1995, 2675:2003-2006. PC12 cells transfected with the PDGF receptor do not undergo apoptosis in the presence of PDGF. Cells transfected with mutant receptors that do not bind PI3K, or cells treated with wortmannin, do undergo apoptosis in the presence of PDGF.
-
(1995)
Science
, vol.2675
, pp. 2003-2006
-
-
Yao, R.1
Cooper, G.M.2
-
23
-
-
0025200830
-
Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae
-
Herman PK, Emr SD: Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae. Mol Cell Biol 1990, 10:6742-6754.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 6742-6754
-
-
Herman, P.K.1
Emr, S.D.2
-
24
-
-
0029148577
-
Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells
-
Brown WJ, DeWald DB, Emr SD, Plutner H, Balch WE: Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells. J Cell Biol 1995, 130:781-796. This paper suggests that D3-phosphorylated lipids are involved in trafficking of vesicles from the Golgi to the lysosome.
-
(1995)
J Cell Biol
, vol.130
, pp. 781-796
-
-
Brown, W.J.1
DeWald, D.B.2
Emr, S.D.3
Plutner, H.4
Balch, W.E.5
-
25
-
-
0029123267
-
Wortmannin causes mistargeting of procathepsin D. Evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes
-
Davidson HW: Wortmannin causes mistargeting of procathepsin D. Evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes. J Cell Biol 1995, 130:797-805. This paper suggests the involvement of D3-phosphorylated lipids in Golgi→lysosome transport.
-
(1995)
J Cell Biol
, vol.130
, pp. 797-805
-
-
Davidson, H.W.1
-
26
-
-
0028388146
-
Characterization of a phosphatidylinositol-specific phosphoinositide 3-kinase from mammalian cells
-
Stephens L, Cooke FT, Walters R, Jackson T, Volinia S, Gout I, Waterfield MD, Hawkins PT: Characterization of a phosphatidylinositol-specific phosphoinositide 3-kinase from mammalian cells. Curr Biol 1994, 4:203-214.
-
(1994)
Curr Biol
, vol.4
, pp. 203-214
-
-
Stephens, L.1
Cooke, F.T.2
Walters, R.3
Jackson, T.4
Volinia, S.5
Gout, I.6
Waterfield, M.D.7
Hawkins, P.T.8
-
27
-
-
0029015694
-
A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids
-
Nakanishi S, Catt JK, Balla T: A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids. Proc Natl Acad Sci USA 1995, 92:5317-5321. This paper describes a PtdIns 4K that is quite senstive to wortmannin, raising the possibility that some effects of wortmannin could be a result of inhibition of PtdIns 4K.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5317-5321
-
-
Nakanishi, S.1
Catt, J.K.2
Balla, T.3
-
28
-
-
0029058288
-
Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor trafficking
-
Joly M, Kazlauskas A, Corvera S: Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor trafficking. J Biol Chem 1995, 270:13225-13230. This paper shows that PI3K is necessary for lysosomal sorting of the PDGF receptor.
-
(1995)
J Biol Chem
, vol.270
, pp. 13225-13230
-
-
Joly, M.1
Kazlauskas, A.2
Corvera, S.3
-
29
-
-
0028786852
-
Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5
-
Li G, D'Souza-Schorey C, Barbieri MA, Roberts RL, Klippel A, Williams LT, Stahl PD: Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5. Proc Natl Acad Sci USA 1995, 92:10207-10211.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 10207-10211
-
-
Li, G.1
D'Souza-Schorey, C.2
Barbieri, M.A.3
Roberts, R.L.4
Klippel, A.5
Williams, L.T.6
Stahl, P.D.7
-
30
-
-
0028308412
-
Phosphatidylinositol 3-kinase activation Is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation
-
Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR: Phosphatidylinositol 3-kinase activation Is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 1994, 14:4902-4911.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 4902-4911
-
-
Cheatham, B.1
Vlahos, C.J.2
Cheatham, L.3
Wang, L.4
Blenis, J.5
Kahn, C.R.6
-
31
-
-
0027374488
-
Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells
-
Yano H, Nakanishi S, Kimura K, Hanai N, Saitoh Y, Fukui Y, Nonomura Y, Matsuda Y: Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J Biol Chem 1993, 268:25846-25856.
-
(1993)
J Biol Chem
, vol.268
, pp. 25846-25856
-
-
Yano, H.1
Nakanishi, S.2
Kimura, K.3
Hanai, N.4
Saitoh, Y.5
Fukui, Y.6
Nonomura, Y.7
Matsuda, Y.8
-
32
-
-
0028953311
-
ATP-dependent inositide phosphorylation required for Ca(2+)-activated secretion
-
Hay JC, Fisette PL, Jenkins GH, Fukami K, Takenawa T, Anderson RA, Martin TF: ATP-dependent inositide phosphorylation required for Ca(2+)-activated secretion. Nature 1995, 3740:173-177. A requirement for PtdIns 4-P 5K in reconstituted neurosecretion in PC12 cells is demonstrated.
-
(1995)
Nature
, vol.3740
, pp. 173-177
-
-
Hay, J.C.1
Fisette, P.L.2
Jenkins, G.H.3
Fukami, K.4
Takenawa, T.5
Anderson, R.A.6
Martin, T.F.7
-
33
-
-
0029019442
-
Signal transduction and membrane traffic: The PITP/phosphoinositide connection
-
Liscovitch M, Cantley LC: Signal transduction and membrane traffic: the PITP/phosphoinositide connection. Cell 1995, 81:659-662.
-
(1995)
Cell
, vol.81
, pp. 659-662
-
-
Liscovitch, M.1
Cantley, L.C.2
-
34
-
-
0029240537
-
Protein regulation by phosphatidylinositol lipids
-
Janmey PA: Protein regulation by phosphatidylinositol lipids. Curr Biol 1995, 2:61-65.
-
(1995)
Curr Biol
, vol.2
, pp. 61-65
-
-
Janmey, P.A.1
-
36
-
-
0029023942
-
Rho family GTPases bind to phosphoinositide kinases
-
Tolias KF, Cantley LC, Carpenter CL: Rho family GTPases bind to phosphoinositide kinases. J Biol Chem 1995, 270:17656-17659.
-
(1995)
J Biol Chem
, vol.270
, pp. 17656-17659
-
-
Tolias, K.F.1
Cantley, L.C.2
Carpenter, C.L.3
-
40
-
-
0029278739
-
PDGF stimulates an increase in GTP-rac via activation of phosphoinositide 3-kinase
-
Hawkins PT, Eguinoa A, Qiu R-G, Stokoe D, Cooke FT, Walters R, Wennstrom S, Claesson-Welsh L, Evans T, Symons M, Stephens L: PDGF stimulates an increase in GTP-rac via activation of phosphoinositide 3-kinase. Curr Biol 1995, 5:393-403. For the first time, a change in the GTP-binding state of Rac is demonstrated, and PI3K is shown to be necessary for the increase in binding of GTP to Rac in response to PDGF.
-
(1995)
Curr Biol
, vol.5
, pp. 393-403
-
-
Hawkins, P.T.1
Eguinoa, A.2
Qiu, R.-G.3
Stokoe, D.4
Cooke, F.T.5
Walters, R.6
Wennstrom, S.7
Claesson-Welsh, L.8
Evans, T.9
Symons, M.10
Stephens, L.11
-
41
-
-
0028837170
-
Activation of the small GTP-binding proteins rho and rac by growth factor receptors
-
Nobes CD, Hawkins P, Stephens L, Hall A: Activation of the small GTP-binding proteins rho and rac by growth factor receptors. J Cell Sci 1995, 108:225-233.
-
(1995)
J Cell Sci
, vol.108
, pp. 225-233
-
-
Nobes, C.D.1
Hawkins, P.2
Stephens, L.3
Hall, A.4
-
42
-
-
0029154701
-
Receptor tyrosine kinase stimulates cell-matrix adhesion by phosphatidylinositol 3 kinase and phospholipase C-gamma 1 pathways
-
Kinashi T, Escobedo JA, Williams LT, Takatsu K, Springer TA: Receptor tyrosine kinase stimulates cell-matrix adhesion by phosphatidylinositol 3 kinase and phospholipase C-gamma 1 pathways. Blood 1995, 86:2086-2090.
-
(1995)
Blood
, vol.86
, pp. 2086-2090
-
-
Kinashi, T.1
Escobedo, J.A.2
Williams, L.T.3
Takatsu, K.4
Springer, T.A.5
-
43
-
-
0028895383
-
Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells
-
Serve H, Yee NS, Stella G, Sepp-Lorenzino L, Tan JC, Besmer P: Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells. EMBO J 1995, 14:473-483.
-
(1995)
EMBO J
, vol.14
, pp. 473-483
-
-
Serve, H.1
Yee, N.S.2
Stella, G.3
Sepp-Lorenzino, L.4
Tan, J.C.5
Besmer, P.6
-
44
-
-
0028560447
-
Activation of protein kinase C family members by the novel polyphosphoinositides PI-3,4-P2 and PI-3,4,5-P3
-
Toker A, Meyer M, Reddy KK, Falck JR, Aneja R, Aneja S, Parra A, Burns DJ, Ballas LM, Cantley LC: Activation of protein kinase C family members by the novel polyphosphoinositides PI-3,4-P2 and PI-3,4,5-P3. J Biol Chem 1994, 269:32358-32367.
-
(1994)
J Biol Chem
, vol.269
, pp. 32358-32367
-
-
Toker, A.1
Meyer, M.2
Reddy, K.K.3
Falck, J.R.4
Aneja, R.5
Aneja, S.6
Parra, A.7
Burns, D.J.8
Ballas, L.M.9
Cantley, L.C.10
-
45
-
-
0028560447
-
Activation of protein kinase C family members by the novel polyphosphoinositides PI-3,4-P2 and PI-3,4,5-P3
-
Toker A, Meyer M, Reddy KK, Falck JR, Aneja R, Aneja S, Parra A, Burns DJ, Ballas LM, Cantley LC: Activation of protein kinase C family members by the novel polyphosphoinositides PI-3,4-P2 and PI-3,4,5-P3. J Biol Chem 1994, 269:32358-32367.
-
(1994)
J Biol Chem
, vol.269
, pp. 32358-32367
-
-
Toker, A.1
Meyer, M.2
Reddy, K.K.3
Falck, J.R.4
Aneja, R.5
Aneja, S.6
Parra, A.7
Burns, D.J.8
Ballas, L.M.9
Cantley, L.C.10
-
46
-
-
0029084949
-
Phosphatidylinositol-3,4,5-trisphosphate stimulates phosphorylation of pleckstrin in human platelets
-
Zhang J, Falck JR, Reddy KR, Abrams CS, Zhao W, Rittenhouse SE: Phosphatidylinositol-3,4,5-trisphosphate stimulates phosphorylation of pleckstrin in human platelets. J Biol Chem 1995, 270:22807-22810.
-
(1995)
J Biol Chem
, vol.270
, pp. 22807-22810
-
-
Zhang, J.1
Falck, J.R.2
Reddy, K.R.3
Abrams, C.S.4
Zhao, W.5
Rittenhouse, S.E.6
-
47
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering BM, Coffer PJ: Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 1995, 376:599-602.
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.1
Coffer, P.J.2
-
48
-
-
0028999052
-
Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation
-
Weng Q-P, Andrabi K, Klippel A, Kozlowski MT, Williams LT, Avruch J: Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation. Proc Natl Acad Sci USA 1995, 92:5744-5748.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5744-5748
-
-
Weng, Q.-P.1
Andrabi, K.2
Klippel, A.3
Kozlowski, M.T.4
Williams, L.T.5
Avruch, J.6
-
49
-
-
0029079275
-
The protein kinase encoded the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
-
Franke TF, Yang S-I, Chan TO, Datta K, Kazlauskas A, Morrison DK, Kaplan DR, Tsichlis PN: The protein kinase encoded the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 1995, 81:1-20.
-
(1995)
Cell
, vol.81
, pp. 1-20
-
-
Franke, T.F.1
Yang, S.-I.2
Chan, T.O.3
Datta, K.4
Kazlauskas, A.5
Morrison, D.K.6
Kaplan, D.R.7
Tsichlis, P.N.8
-
50
-
-
0028021882
-
Pleckstrin homology domains bind to phosphatidylinositol-4,5- Bisphosphate
-
Harlan JE, Hajduk PJ, Yoon HS, Fesik SW: Pleckstrin homology domains bind to phosphatidylinositol-4,5- bisphosphate. Nature 1994, 371:168-170. The first demonstration that pleckstrin homology domains are able to bind phosphoinositides.
-
(1994)
Nature
, vol.371
, pp. 168-170
-
-
Harlan, J.E.1
Hajduk, P.J.2
Yoon, H.S.3
Fesik, S.W.4
-
51
-
-
0028040136
-
D-myo-inositol 1,4,5-trisphosphate inhibits binding of phospholipase C-delta 1 to bilayer membranes
-
Cifuentes ME, Delaney T, Rebecchi MJ: D-myo-inositol 1,4,5-trisphosphate inhibits binding of phospholipase C-delta 1 to bilayer membranes. J Biol Chem 1994, 269:1945-1948.
-
(1994)
J Biol Chem
, vol.269
, pp. 1945-1948
-
-
Cifuentes, M.E.1
Delaney, T.2
Rebecchi, M.J.3
-
52
-
-
0028132554
-
Expression and characterization of an inositol 1,4,5-trisphosphate binding domain of phosphatidylinositol-specific phospholipase C-delta 1
-
Yagisawa H, Hirata M, Kanematsu T, Watanabe Y, Ozaki S, Sakuma K, Tanaka H, Yabuta N, Kamata H, Hirata H et al.: Expression and characterization of an inositol 1,4,5-trisphosphate binding domain of phosphatidylinositol-specific phospholipase C-delta 1. J Biol Chem 1994, 269:20179-20188.
-
(1994)
J Biol Chem
, vol.269
, pp. 20179-20188
-
-
Yagisawa, H.1
Hirata, M.2
Kanematsu, T.3
Watanabe, Y.4
Ozaki, S.5
Sakuma, K.6
Tanaka, H.7
Yabuta, N.8
Kamata, H.9
Hirata, H.10
-
53
-
-
0028892253
-
Phosphatidylinositol-3,4,5-P3 interacts with SH2 domains and modulates phosphoinositide 3-kinase association with tyrosine-phosphorylated proteins
-
Rameh L, Chen C-S, Cantley LC: Phosphatidylinositol-3,4,5-P3 interacts with SH2 domains and modulates phosphoinositide 3-kinase association with tyrosine-phosphorylated proteins. Cell 1995, 83:821-830.
-
(1995)
Cell
, vol.83
, pp. 821-830
-
-
Rameh, L.1
Chen, C.-S.2
Cantley, L.C.3
|