-
1
-
-
0029965138
-
Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires
-
Goodnow, C.C. 1996. Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires. Proc. Natl. Acad. Sci. USA. 93:2264-2271.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 2264-2271
-
-
Goodnow, C.C.1
-
2
-
-
0027447188
-
Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death
-
Hartley, S.B., M.P. Cooke, D.A. Fulcher, A.W. Harris, S. Cory, A. Basten, and C.C. Goodnow. 1993. Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death. Cell. 72:325-335.
-
(1993)
Cell
, vol.72
, pp. 325-335
-
-
Hartley, S.B.1
Cooke, M.P.2
Fulcher, D.A.3
Harris, A.W.4
Cory, S.5
Basten, A.6
Goodnow, C.C.7
-
3
-
-
0024529870
-
Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes
-
Nemazee, D., and K. Bürki. 1989. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes. Nature (Lond.). 337:562-566.
-
(1989)
Nature (Lond.)
, vol.337
, pp. 562-566
-
-
Nemazee, D.1
Bürki, K.2
-
4
-
-
0026762942
-
Transgenic mice and analysis of B-cell tolerance
-
Goodnow, C.C. 1992. Transgenic mice and analysis of B-cell tolerance. Annu. Rev. Immunol. 10:489-518.
-
(1992)
Annu. Rev. Immunol.
, vol.10
, pp. 489-518
-
-
Goodnow, C.C.1
-
5
-
-
0030250062
-
The "clonal selection hypothesis" and current concepts of B cell tolerance
-
Klinman, N.R. 1996. The "clonal selection hypothesis" and current concepts of B cell tolerance. Immunity. 5:189-195.
-
(1996)
Immunity
, vol.5
, pp. 189-195
-
-
Klinman, N.R.1
-
6
-
-
0025817420
-
Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen
-
Adelstein, S., H. Pritchard-Briscoe, T.A. Anderson, J. Crosbie, G. Gammon, R.H. Loblay, A. Basten, and C.C. Goodnow. 1991. Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen. Science (Wash. DC). 251:1223-1225.
-
(1991)
Science (Wash. DC)
, vol.251
, pp. 1223-1225
-
-
Adelstein, S.1
Pritchard-Briscoe, H.2
Anderson, T.A.3
Crosbie, J.4
Gammon, G.5
Loblay, R.H.6
Basten, A.7
Goodnow, C.C.8
-
7
-
-
0025923308
-
Clonal deletion of autospecific B lymphocytes
-
Nemazee, D., D. Russell, B. Arnold, G. Haemmerling, J. Allison, J.F. Miller, G. Morahan, and K. Buerki. 1991. Clonal deletion of autospecific B lymphocytes. Immunol. Rev. 122: 117-132.
-
(1991)
Immunol. Rev.
, vol.122
, pp. 117-132
-
-
Nemazee, D.1
Russell, D.2
Arnold, B.3
Haemmerling, G.4
Allison, J.5
Miller, J.F.6
Morahan, G.7
Buerki, K.8
-
8
-
-
0030901968
-
The CD19/21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity
-
Tedder, T.F., M. Inaoki, and S. Sato. 1997. The CD19/21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity. Immunity. 6:107-118.
-
(1997)
Immunity
, vol.6
, pp. 107-118
-
-
Tedder, T.F.1
Inaoki, M.2
Sato, S.3
-
9
-
-
0029987839
-
The instructive role of innate immunity in the acquired immune response
-
Fearon, D.T., and R.M. Locksley. 1996. The instructive role of innate immunity in the acquired immune response. Science (Wash. DC). 272:50-54.
-
(1996)
Science (Wash. DC)
, vol.272
, pp. 50-54
-
-
Fearon, D.T.1
Locksley, R.M.2
-
10
-
-
0026587743
-
CD19: Lowering the threshold for antigen receptor stimulation of B lymphocytes
-
Carter, R.H., and D.T. Fearon. 1992. CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes. Science (Wash. DC). 256:105-107.
-
(1992)
Science (Wash. DC)
, vol.256
, pp. 105-107
-
-
Carter, R.H.1
Fearon, D.T.2
-
11
-
-
0030593030
-
C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity
-
Dempsey, P.W., M.E.D. Allison, S. Akkaraju, C.C. Goodnow, and D.T. Fearon. 1996. C3d of complement as a molecular adjuvant: bridging innate and acquired immunity. Science (Wash. DC). 271:348-350.
-
(1996)
Science (Wash. DC)
, vol.271
, pp. 348-350
-
-
Dempsey, P.W.1
Allison, M.E.D.2
Akkaraju, S.3
Goodnow, C.C.4
Fearon, D.T.5
-
12
-
-
0029094609
-
Abnormal B lymphocyte development, activation and differentiation in mice that lack or overexpress the CD19 signal transduction molecule
-
Engel, P., L.-J. Zhou, D.C. Ord, S. Sato, B. Koller, and T.F. Tedder. 1995. Abnormal B lymphocyte development, activation and differentiation in mice that lack or overexpress the CD19 signal transduction molecule. Immunity. 3:39-50.
-
(1995)
Immunity
, vol.3
, pp. 39-50
-
-
Engel, P.1
Zhou, L.-J.2
Ord, D.C.3
Sato, S.4
Koller, B.5
Tedder, T.F.6
-
13
-
-
0029064680
-
Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice
-
Rickert, R.C., K. Rajewsky, and J. Roes. 1995. Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice. Nature (Lond.). 376: 352-355.
-
(1995)
Nature (Lond.)
, vol.376
, pp. 352-355
-
-
Rickert, R.C.1
Rajewsky, K.2
Roes, J.3
-
14
-
-
0029558617
-
The CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation
-
Sato, S., D.A. Steeber, and T.F. Tedder. 1995. The CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation. Proc. Natl. Acad. Sci. USA. 92:11558-11562.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 11558-11562
-
-
Sato, S.1
Steeber, D.A.2
Tedder, T.F.3
-
15
-
-
0028355752
-
Tissue-specific expression of the human CD19 gene in transgenic mice inhibits antigen-independent B lymphocyte development
-
Zhou, L.-J., H.M. Smith, T.J. Waldschmidt, R. Schwarting, J. Daley, and T.F. Tedder. 1994. Tissue-specific expression of the human CD19 gene in transgenic mice inhibits antigen-independent B lymphocyte development. Mol. Cell. Biol. 14: 3884-3894.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 3884-3894
-
-
Zhou, L.-J.1
Smith, H.M.2
Waldschmidt, T.J.3
Schwarting, R.4
Daley, J.5
Tedder, T.F.6
-
16
-
-
0030588569
-
CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity
-
Sato, S., N. Ono, D.A. Steeber, D.S. Pisetsky, and T.F. Tedder. 1996. CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity. J. Immunol. 156:4371-4378.
-
(1996)
J. Immunol.
, vol.156
, pp. 4371-4378
-
-
Sato, S.1
Ono, N.2
Steeber, D.A.3
Pisetsky, D.S.4
Tedder, T.F.5
-
17
-
-
0023729241
-
Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
-
Goodnow, C.C., J. Crosbie, S. Adelstein, T.B. Lavoie, S.J. Smith-Gill, R.A. Brink, H. Pritchard-Briscoe, J.S. Wotherspoon, R.H. Loblay, K. Raphael et al. 1988. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature (Lond.). 334:676-682.
-
(1988)
Nature (Lond.)
, vol.334
, pp. 676-682
-
-
Goodnow, C.C.1
Crosbie, J.2
Adelstein, S.3
Lavoie, T.B.4
Smith-Gill, S.J.5
Brink, R.A.6
Pritchard-Briscoe, H.7
Wotherspoon, J.S.8
Loblay, R.H.9
Raphael, K.10
-
18
-
-
0031253851
-
Regulation of B lymphocyte development and activation by the CD19/CD21/CD81/Leu 13 complex requires the cytoplasmic domain of CD19
-
Sato, S., A.S. Miller, M.C. Howard, and T.F. Tedder. 1997. Regulation of B lymphocyte development and activation by the CD19/CD21/CD81/Leu 13 complex requires the cytoplasmic domain of CD19. J. Immunol. 159:3278-3287.
-
(1997)
J. Immunol.
, vol.159
, pp. 3278-3287
-
-
Sato, S.1
Miller, A.S.2
Howard, M.C.3
Tedder, T.F.4
-
19
-
-
0031570122
-
CD19 expression levels regulate B lymphocyte development: Human CD19 restores normal function in mice lacking endogenous CD19
-
Sato, S., D.A. Steeber, P.J. Jansen, and T.F. Tedder. 1997. CD19 expression levels regulate B lymphocyte development: human CD19 restores normal function in mice lacking endogenous CD19. J. Immunol. 158:4662-4669.
-
(1997)
J. Immunol.
, vol.158
, pp. 4662-4669
-
-
Sato, S.1
Steeber, D.A.2
Jansen, P.J.3
Tedder, T.F.4
-
20
-
-
0025948793
-
Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
-
Hartley, S.B., J. Crosbie, R. Brink, A.A. Kantor, A. Basten, and C.C. Goodnow. 1991. Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens. Nature (Lond.). 353:765-769.
-
(1991)
Nature (Lond.)
, vol.353
, pp. 765-769
-
-
Hartley, S.B.1
Crosbie, J.2
Brink, R.3
Kantor, A.A.4
Basten, A.5
Goodnow, C.C.6
-
21
-
-
0024455288
-
Induction of self-tolerance in mature peripheral B lymphocytes
-
Goodnow, C.C., J. Crosbie, H. Jorgensen, R.A. Brink, and A. Basten. 1989. Induction of self-tolerance in mature peripheral B lymphocytes. Nature (Lond.). 342:385-391.
-
(1989)
Nature (Lond.)
, vol.342
, pp. 385-391
-
-
Goodnow, C.C.1
Crosbie, J.2
Jorgensen, H.3
Brink, R.A.4
Basten, A.5
-
22
-
-
0030499431
-
CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: Altered signaling in CD22-deficient mice
-
Sato, S., A.S. Miller, M. Inaoki, C.B. Bock, P.J. Jansen, M.L.K. Tang, and T.F. Tedder. 1996. CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. Immunity. 5:551-562.
-
(1996)
Immunity
, vol.5
, pp. 551-562
-
-
Sato, S.1
Miller, A.S.2
Inaoki, M.3
Bock, C.B.4
Jansen, P.J.5
Tang, M.L.K.6
Tedder, T.F.7
-
23
-
-
0026758271
-
The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules
-
Bradbury, L.E., G.S. Kansas, S. Levy, R.L. Evans, and T.F. Tedder. 1992. The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules. J. Immunol. 149:2841-2850.
-
(1992)
J. Immunol.
, vol.149
, pp. 2841-2850
-
-
Bradbury, L.E.1
Kansas, G.S.2
Levy, S.3
Evans, R.L.4
Tedder, T.F.5
-
24
-
-
0026533967
-
Development and follicular localization of tolerant B lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic mice
-
Mason, D.Y., M. Jones, and C.C. Goodnow. 1992. Development and follicular localization of tolerant B lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic mice. Intl. Immunol. 4:163-175.
-
(1992)
Intl. Immunol.
, vol.4
, pp. 163-175
-
-
Mason, D.Y.1
Jones, M.2
Goodnow, C.C.3
-
25
-
-
0028127965
-
Immunoglobulin signal transductibn guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells
-
Cooke, M.P., A.W. Heath, K.M. Shokat, Y. Zeng, F.D. Finkelman, P.S. Linsley, M. Howard, and C.C. Goodnow. 1994. Immunoglobulin signal transductibn guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells. J. Exp. Med. 179:425-438.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 425-438
-
-
Cooke, M.P.1
Heath, A.W.2
Shokat, K.M.3
Zeng, Y.4
Finkelman, F.D.5
Linsley, P.S.6
Howard, M.7
Goodnow, C.C.8
-
26
-
-
0028961264
-
Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection
-
Cyster, J.G., and C.C. Goodnow. 1995. Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection. Immunity. 2:13-24.
-
(1995)
Immunity
, vol.2
, pp. 13-24
-
-
Cyster, J.G.1
Goodnow, C.C.2
-
27
-
-
26744451309
-
CD19 and CD22 reciprocally regulate Vav tyrosine phosphorylation during B lymphocyte signaling
-
In press
-
Sato, S., P.J. Jansen, and T.F. Tedder. 1997. CD19 and CD22 reciprocally regulate Vav tyrosine phosphorylation during B lymphocyte signaling. Proc. Natl. Acad. Sci. USA. In press.
-
(1997)
Proc. Natl. Acad. Sci. USA
-
-
Sato, S.1
Jansen, P.J.2
Tedder, T.F.3
-
28
-
-
0001853916
-
Murine models of lupus
-
R.G. Lahita, editor. Churchill Livingston, Edinburgh
-
Theofilopoulos, A.N. 1992. Murine models of lupus. In Systemic Lupus Erythematosus. R.G. Lahita, editor. Churchill Livingston, Edinburgh. 121-194.
-
(1992)
Systemic Lupus Erythematosus
, pp. 121-194
-
-
Theofilopoulos, A.N.1
-
29
-
-
0028129894
-
Effects of the lpr mutation on elimination and inactivation of self-reactive B cells
-
Rathmell, J.C., and C.C. Goodnow. 1994. Effects of the lpr mutation on elimination and inactivation of self-reactive B cells. J. Immunol. 153:2831-2842.
-
(1994)
J. Immunol.
, vol.153
, pp. 2831-2842
-
-
Rathmell, J.C.1
Goodnow, C.C.2
-
30
-
-
0029285129
-
Quantitative flocytometric analysis of B cell surface antigens in patients with autoimmune diseases
-
Oooto, Y., T. Ikemoto, T. Nakagawa, and A. Shimizu. 1995. Quantitative flocytometric analysis of B cell surface antigens in patients with autoimmune diseases. Jpn. J. Clin. Pathol. 43:381-384.
-
(1995)
Jpn. J. Clin. Pathol.
, vol.43
, pp. 381-384
-
-
Oooto, Y.1
Ikemoto, T.2
Nakagawa, T.3
Shimizu, A.4
-
31
-
-
0030023652
-
Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45
-
Cyster, J.G., J.I. Healy, K. Kishihara, T.W. Mak, M.L. Thomas, and C.C. Goodnow. 1996. Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45. Nature (Lond.). 381:325-328.
-
(1996)
Nature (Lond.)
, vol.381
, pp. 325-328
-
-
Cyster, J.G.1
Healy, J.I.2
Kishihara, K.3
Mak, T.W.4
Thomas, M.L.5
Goodnow, C.C.6
-
32
-
-
0026060647
-
Intersection of the complement and immune systems: A signal transduction complex of the B lymphocyte containing complement receptor type 2 and CD19
-
Matsumoto, A.K., J. Kopicky-Burd, R.H. Carter, D.A. Tuveson, T.F. Tedder, and D.T. Fearon. 1991. Intersection of the complement and immune systems: a signal transduction complex of the B lymphocyte containing complement receptor type 2 and CD19. J. Exp. Med. 173:55-64.
-
(1991)
J. Exp. Med.
, vol.173
, pp. 55-64
-
-
Matsumoto, A.K.1
Kopicky-Burd, J.2
Carter, R.H.3
Tuveson, D.A.4
Tedder, T.F.5
Fearon, D.T.6
-
33
-
-
0017102756
-
Role of complement in the induction of immunological responses
-
Pepys, M.B. 1976. Role of complement in the induction of immunological responses. Transplant. Rev. 32:93-120.
-
(1976)
Transplant. Rev.
, vol.32
, pp. 93-120
-
-
Pepys, M.B.1
-
34
-
-
0022388544
-
Growth control of activated, synchronized murine B cells by the C3d fragment of human complement
-
Melchers, F., A. Erdei, T. Schulz, and M.P. Dierich. 1985. Growth control of activated, synchronized murine B cells by the C3d fragment of human complement. Nature (Lond.). 317:264-267.
-
(1985)
Nature (Lond.)
, vol.317
, pp. 264-267
-
-
Melchers, F.1
Erdei, A.2
Schulz, T.3
Dierich, M.P.4
-
35
-
-
0028958669
-
The CD19/CR2/ TAPA-1 complex of B lymphocytes: Linking natural to acquired immunity
-
Fearon, D.T., and R.H. Carter. 1995. The CD19/CR2/ TAPA-1 complex of B lymphocytes: linking natural to acquired immunity. Annu. Rev. Immunol. 13:127-149.
-
(1995)
Annu. Rev. Immunol.
, vol.13
, pp. 127-149
-
-
Fearon, D.T.1
Carter, R.H.2
-
36
-
-
15844412034
-
Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen
-
Ahearn, J.M., M.B. Fischer, D. Croix, S. Goerg, M. Ma, J. Xia, X. Zhou, R.G. Howard, T.L. Rothstein, and M.C. Carroll. 1996. Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen. Immunity. 4:251-262.
-
(1996)
Immunity
, vol.4
, pp. 251-262
-
-
Ahearn, J.M.1
Fischer, M.B.2
Croix, D.3
Goerg, S.4
Ma, M.5
Xia, J.6
Zhou, X.7
Howard, R.G.8
Rothstein, T.L.9
Carroll, M.C.10
-
37
-
-
0029926153
-
Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2
-
Molina, H., V.M. Holers, B. Li, Y.-F. Fang, S. Mariathasan, J. Goellner, J. Strauss-Schoenberger, R.W. Karr, and D.D. Chaplin. 1996. Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2. Proc. Natl. Acad. Sci. USA. 93:3357-3361.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 3357-3361
-
-
Molina, H.1
Holers, V.M.2
Li, B.3
Fang, Y.-F.4
Mariathasan, S.5
Goellner, J.6
Strauss-Schoenberger, J.7
Karr, R.W.8
Chaplin, D.D.9
|