Qualitative regulation of B cell antigen receptor signaling by CD19: Selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilization

Journal of Experimental Medicine

Volumn 186, Issue 11, 1997, Pages 1897-1910

  Buhl, Anne Mette ^a   Pleiman, Christopher M ^c   Rickert, Robert C ^d   Cambier, John C ^a,b  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c Cadus Pharmaceutical Corporation   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE ANTIGEN; CALCIUM ION; CD19 ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE;

ANTIGEN BINDING; ARTICLE; CALCIUM MOBILIZATION; DOSE TIME EFFECT RELATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; HYDROLYSIS; PRIORITY JOURNAL; QUALITATIVE DIAGNOSIS; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; ANTIGENS, CD19; BINDING SITES; CALCIUM; DNA, COMPLEMENTARY; ENZYME INHIBITORS; EXTRACELLULAR SPACE; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE; INTRACELLULAR FLUID; MAST-CELL SARCOMA; MICE; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-TYROSINE KINASES; RECEPTORS, ANTIGEN, B-CELL; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SPLEEN; TUMOR CELLS, CULTURED;

EID: 0030734715     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.186.11.1897     Document Type: Article

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