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Volumn 8, Issue 4, 1998, Pages 497-508

Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection

Author keywords

[No Author keywords available]

Indexed keywords

CD22 ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 0032055828     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80554-3     Document Type: Article
Times cited : (387)

References (49)
  • 1
    • 0031468121 scopus 로고    scopus 로고
    • Self-reactive B cells are neither eliminated nor inactivated by autoantigen expressed on thyroid epithelial cells
    • Akkaraju, S., Canaan, K., and Goodnow, C.C. (1997). Self-reactive B cells are neither eliminated nor inactivated by autoantigen expressed on thyroid epithelial cells. J. Exp. Med. 186, 2005-2012.
    • (1997) J. Exp. Med. , vol.186 , pp. 2005-2012
    • Akkaraju, S.1    Canaan, K.2    Goodnow, C.C.3
  • 2
    • 0028157607 scopus 로고
    • A selective defect in IgM antigen receptor synthesis and transport causes loss of cell surface IgM expression on tolerant B lymphocytes
    • Bell, S.E., and Goodnow, C.C. (1994). A selective defect in IgM antigen receptor synthesis and transport causes loss of cell surface IgM expression on tolerant B lymphocytes. EMBO J. 13, 816-826.
    • (1994) EMBO J. , vol.13 , pp. 816-826
    • Bell, S.E.1    Goodnow, C.C.2
  • 3
    • 0030891168 scopus 로고    scopus 로고
    • Leukocyte protein tyrosine kinases: Potential targets for drug discovery
    • Bolen, J.B., and Brugge, J.S. (1997). Leukocyte protein tyrosine kinases: potential targets for drug discovery. Annu. Rev. Immunol. 15, 371-404.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 371-404
    • Bolen, J.B.1    Brugge, J.S.2
  • 4
    • 0028880729 scopus 로고
    • Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene
    • Bories, J.-C., Willerford, D.M., Grévin, D., Davidson, L., Camus, A., Martin, P., Stéhelin, D., and Alt, F.W. (1995). Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene. Nature 377, 635-638.
    • (1995) Nature , vol.377 , pp. 635-638
    • Bories, J.-C.1    Willerford, D.M.2    Grévin, D.3    Davidson, L.4    Camus, A.5    Martin, P.6    Stéhelin, D.7    Alt, F.W.8
  • 5
    • 0025739498 scopus 로고
    • Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases
    • Burkhardt, A.L., Brunswick, M., Bolen, J.B., and Mond, J.J. (1991). Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases. Proc. Natl. Acad. Sci. USA 88, 7410-7414.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7410-7414
    • Burkhardt, A.L.1    Brunswick, M.2    Bolen, J.B.3    Mond, J.J.4
  • 6
    • 0026637001 scopus 로고
    • Association between B-lymphocyte membrane immunoglobulin and multiple members of the src family of protein tyrosine kinases
    • Campbell, M.A., and Sefton, B.M. (1992). Association between B-lymphocyte membrane immunoglobulin and multiple members of the src family of protein tyrosine kinases. Mol. Cell. Biol. 12, 2315-2321.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2315-2321
    • Campbell, M.A.1    Sefton, B.M.2
  • 7
    • 0029048060 scopus 로고
    • Phosphotyrosine-dependent association between CD22 and the protein tyrosine phosphatase 1C
    • Campbell, M.A., and Klinman, N.R. (1995). Phosphotyrosine-dependent association between CD22 and the protein tyrosine phosphatase 1C. Eur. J. Immunol. 25, 1573-1579.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1573-1579
    • Campbell, M.A.1    Klinman, N.R.2
  • 8
    • 0030740148 scopus 로고    scopus 로고
    • Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and downregulation
    • Chan, V.W.F., Meng, F., Soriano, P., DeFranco, A.L., and Lowell, C.A. (1997). Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and downregulation. Immunity 7, 69-81.
    • (1997) Immunity , vol.7 , pp. 69-81
    • Chan, V.W.F.1    Meng, F.2    Soriano, P.3    Defranco, A.L.4    Lowell, C.A.5
  • 9
    • 0028961264 scopus 로고
    • Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection
    • Cyster, J.G., and Goodnow, C.C. (1995). Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection. Immunity 2, 13-24.
    • (1995) Immunity , vol.2 , pp. 13-24
    • Cyster, J.G.1    Goodnow, C.C.2
  • 10
    • 0030950344 scopus 로고    scopus 로고
    • Tuning antigen receptor signaling by CD22: Integrating cues from antigens and the microenvironment
    • Cyster, J.G., and Goodnow, C.C. (1997). Tuning antigen receptor signaling by CD22: integrating cues from antigens and the microenvironment. Immunity 6, 509-517.
    • (1997) Immunity , vol.6 , pp. 509-517
    • Cyster, J.G.1    Goodnow, C.C.2
  • 11
    • 0030023652 scopus 로고    scopus 로고
    • CD45 sets thresholds for negative and positive selection of B lymphocytes
    • Cyster, J.G., Healy, J.I., Kishihara, K., Mak, T.W., Thomas, M.L., and Goodnow, C.C. (1996). CD45 sets thresholds for negative and positive selection of B lymphocytes. Nature 381, 325-328.
    • (1996) Nature , vol.381 , pp. 325-328
    • Cyster, J.G.1    Healy, J.I.2    Kishihara, K.3    Mak, T.W.4    Thomas, M.L.5    Goodnow, C.C.6
  • 12
    • 0030831199 scopus 로고    scopus 로고
    • The complexity of signaling pathways activated by the BCR
    • DeFranco, A.L. (1997). The complexity of signaling pathways activated by the BCR. Curr. Opin. Immunol. 9, 296-308.
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 296-308
    • DeFranco, A.L.1
  • 14
    • 0028990463 scopus 로고
    • Genetic contributions to lupus-like disease in (NZBxNZW)F1 mice
    • Drake, C.G., Rozzo, S.J., Vyse, T.J., Palmer, E., and Kotzin, B.L. (1995). Genetic contributions to lupus-like disease in (NZBxNZW)F1 mice. Immunol. Rev. 144, 51-74.
    • (1995) Immunol. Rev. , vol.144 , pp. 51-74
    • Drake, C.G.1    Rozzo, S.J.2    Vyse, T.J.3    Palmer, E.4    Kotzin, B.L.5
  • 15
    • 0025761215 scopus 로고
    • Ligation of membrane Ig leads to calcium-mediated phosphorylation of the proto-oncogene product, Ets-1
    • Fisher, C.L., Ghysdael, J., and Gambier, J.C. (1991). Ligation of membrane Ig leads to calcium-mediated phosphorylation of the proto-oncogene product, Ets-1. J. Immunol. 146, 1743-1749.
    • (1991) J. Immunol. , vol.146 , pp. 1743-1749
    • Fisher, C.L.1    Ghysdael, J.2    Gambier, J.C.3
  • 16
    • 0029965138 scopus 로고    scopus 로고
    • Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires
    • Goodnow, C.C. (1996). Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires. Proc. Natl. Acad. Sci. USA 93, 2264-2271.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2264-2271
    • Goodnow, C.C.1
  • 18
    • 0024455288 scopus 로고
    • Induction of self-tolerance in mature peripheral B lymphocytes
    • Goodnow, C.C., Crosbie, J., Jorgensen, H., Brink, R.A., and Basten, A. (1989). Induction of self-tolerance in mature peripheral B lymphocytes. Nature 342, 385-391.
    • (1989) Nature , vol.342 , pp. 385-391
    • Goodnow, C.C.1    Crosbie, J.2    Jorgensen, H.3    Brink, R.A.4    Basten, A.5
  • 19
    • 0025948793 scopus 로고
    • Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
    • Hartley, S.B., Crosbie, J., Brink, R., Kantor, A.A., Basten, A., and Goodnow, C.C. (1991). Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens. Nature 353, 765-768.
    • (1991) Nature , vol.353 , pp. 765-768
    • Hartley, S.B.1    Crosbie, J.2    Brink, R.3    Kantor, A.A.4    Basten, A.5    Goodnow, C.C.6
  • 20
    • 0027447188 scopus 로고
    • Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death
    • Hartley, S.B., Cooke, M.P., Fulcher, D.A., Harris, A.W., Cory, S., Basten, A., and Goodnow, C.C. (1993). Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death. Cell 72, 325-335.
    • (1993) Cell , vol.72 , pp. 325-335
    • Hartley, S.B.1    Cooke, M.P.2    Fulcher, D.A.3    Harris, A.W.4    Cory, S.5    Basten, A.6    Goodnow, C.C.7
  • 21
  • 22
    • 0030795735 scopus 로고    scopus 로고
    • Molecular mechanisms in B cell antigen receptor signaling
    • Kurosaki, T. (1997). Molecular mechanisms in B cell antigen receptor signaling. Curr. Opin. Immunol. 9, 309-318.
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 309-318
    • Kurosaki, T.1
  • 24
    • 0030047811 scopus 로고    scopus 로고
    • CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-γ1 upon B cell activation
    • Law, C.-L., Sidorenko, S.P., Chandran, K.A., Zhao, Z., Shen, S.-H., Fischer, E.H., and Clark, E.A. (1996). CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-γ1 upon B cell activation. J. Exp. Med. 183, 547-560.
    • (1996) J. Exp. Med. , vol.183 , pp. 547-560
    • Law, C.-L.1    Sidorenko, S.P.2    Chandran, K.A.3    Zhao, Z.4    Shen, S.-H.5    Fischer, E.H.6    Clark, E.A.7
  • 26
    • 0026533967 scopus 로고
    • Development and follicular localization of tolerant lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic mice
    • Mason, D.Y., Jones, M., and Goodnow, C.C. (1992). Development and follicular localization of tolerant lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic mice. Int. Immunol. 4, 163-175.
    • (1992) Int. Immunol. , vol.4 , pp. 163-175
    • Mason, D.Y.1    Jones, M.2    Goodnow, C.C.3
  • 27
    • 0031179651 scopus 로고    scopus 로고
    • Genetic dissection of systemic lupus erythematosus pathogenesis
    • Mohan, C., Morel, L., Yang, P., and Wakeland, E.K. (1997). Genetic dissection of systemic lupus erythematosus pathogenesis. J. Immunol. 159, 454-465.
    • (1997) J. Immunol. , vol.159 , pp. 454-465
    • Mohan, C.1    Morel, L.2    Yang, P.3    Wakeland, E.K.4
  • 28
  • 29
    • 0031570375 scopus 로고    scopus 로고
    • Functional dissection of systemic lupus erythematosus using congenic mouse strains
    • Morel, L., Mohan, C., Ying, Y., Croker, B.P., Tian, N., Deng, A., and Wakeland, E.K. (1997). Functional dissection of systemic lupus erythematosus using congenic mouse strains. J. Immunol. 158, 6019-6028.
    • (1997) J. Immunol. , vol.158 , pp. 6019-6028
    • Morel, L.1    Mohan, C.2    Ying, Y.3    Croker, B.P.4    Tian, N.5    Deng, A.6    Wakeland, E.K.7
  • 30
    • 0028806216 scopus 로고
    • Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyndeficient mice
    • Nishizumi, H., Taniuchi, I., Yamanashi, Y., Kitamura, D., Ilic, D., Mori, S., Watanabe, T., and Yamamoto, T. (1995). Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyndeficient mice. Immunity 3, 549-560.
    • (1995) Immunity , vol.3 , pp. 549-560
    • Nishizumi, H.1    Taniuchi, I.2    Yamanashi, Y.3    Kitamura, D.4    Ilic, D.5    Mori, S.6    Watanabe, T.7    Yamamoto, T.8
  • 34
    • 0027175115 scopus 로고
    • Association of CD22 with the B cell antigen receptor
    • Peaker, C.J., and Neuberger, M.S. (1993). Association of CD22 with the B cell antigen receptor. Eur. J. Immunol. 23, 1358-1363.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1358-1363
    • Peaker, C.J.1    Neuberger, M.S.2
  • 35
    • 0028129894 scopus 로고
    • Effects of the lpr mutation on elimination and inactivation of self-reactive B cells
    • Rathmell, J.C., and Goodnow, C.C. (1994). Effects of the lpr mutation on elimination and inactivation of self-reactive B cells. J. Immunol. 153, 2831-2842.
    • (1994) J. Immunol. , vol.153 , pp. 2831-2842
    • Rathmell, J.C.1    Goodnow, C.C.2
  • 36
    • 0030499431 scopus 로고    scopus 로고
    • CD22 is both a positive and a negative regulator of B lymphocyte antigen receptor signal transduction: Altered signaling in CD22-deficient mice
    • Sato, S., Miller, A.S., Inaoki, M., Bock, C.B., Jansen, P.J., Tang, M.L., and Tedder, T.F. (1996). CD22 is both a positive and a negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. Immunity 5, 551-562.
    • (1996) Immunity , vol.5 , pp. 551-562
    • Sato, S.1    Miller, A.S.2    Inaoki, M.3    Bock, C.B.4    Jansen, P.J.5    Tang, M.L.6    Tedder, T.F.7
  • 37
    • 0031570122 scopus 로고    scopus 로고
    • CD19 expression levels regulate B lymphocyte development: Human CD19 restores normal function in mice lacking endogenous CD19
    • Sato, S., Steeber, D.A., Jansen, P.J., and Tedder, T.F. (1997). CD19 expression levels regulate B lymphocyte development: human CD19 restores normal function in mice lacking endogenous CD19. J. Immunol. 158, 4662-4669.
    • (1997) J. Immunol. , vol.158 , pp. 4662-4669
    • Sato, S.1    Steeber, D.A.2    Jansen, P.J.3    Tedder, T.F.4
  • 38
    • 0025997867 scopus 로고
    • Ras and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase
    • Simon, M.A., Bowtell, D.D.L., Dodson, G.S., Laverty, T.R., and Rubin, G.M. (1991) Ras and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase. Cell 67, 701-716.
    • (1991) Cell , vol.67 , pp. 701-716
    • Simon, M.A.1    Bowtell, D.D.L.2    Dodson, G.S.3    Laverty, T.R.4    Rubin, G.M.5
  • 40
    • 0028869486 scopus 로고
    • The basis of autoimmunity: Part I. Mechanisms of aberrant self-recognition
    • Theofilopoulos, A.N. (1995a). The basis of autoimmunity: Part I. Mechanisms of aberrant self-recognition. Immunol. Today 16, 90-98.
    • (1995) Immunol. Today , vol.16 , pp. 90-98
    • Theofilopoulos, A.N.1
  • 41
    • 0028919313 scopus 로고
    • The basis of autoimmunity: Part II. Genetic predisposition
    • Theofilopoulos, A.N. (1995b). The basis of autoimmunity: Part II. Genetic predisposition. Immunol. Today 16, 150-159.
    • (1995) Immunol. Today , vol.16 , pp. 150-159
    • Theofilopoulos, A.N.1
  • 42
    • 0030834178 scopus 로고    scopus 로고
    • Counterregulation by the coreceptors CD19 and CD22 of MAP kinase activation by membrane immunoglobulin
    • Tooze, R.M., Doody, G.M., and Fearon, D.T. (1997). Counterregulation by the coreceptors CD19 and CD22 of MAP kinase activation by membrane immunoglobulin. Immunity 7, 59-67.
    • (1997) Immunity , vol.7 , pp. 59-67
    • Tooze, R.M.1    Doody, G.M.2    Fearon, D.T.3
  • 43
    • 0030053270 scopus 로고    scopus 로고
    • Involvement of p72syk kinase, p53/56lyn kinase and phosphatidylinositol-3 kinase in signal transduction via the human B lymphocyte antigen CD22
    • Tuscano, J., Engel, P., Tedder, T.F., Agarwal, A., and Kehrl, J.H. (1996). Involvement of p72syk kinase, p53/56lyn kinase and phosphatidylinositol-3 kinase in signal transduction via the human B lymphocyte antigen CD22. Eur. J. Immunol. 26, 1246-1252.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1246-1252
    • Tuscano, J.1    Engel, P.2    Tedder, T.F.3    Agarwal, A.4    Kehrl, J.H.5
  • 44
    • 0029985177 scopus 로고    scopus 로고
    • Analysis of dominant enhancers and suppressors of activated Notch in Drosophila
    • Verheyen, E.M., Purcell, K.J., Fortinin, M.E., and Artavanis-Tsakonas, S. (1996). Analysis of dominant enhancers and suppressors of activated Notch in Drosophila. Genetics 144, 1127-1141.
    • (1996) Genetics , vol.144 , pp. 1127-1141
    • Verheyen, E.M.1    Purcell, K.J.2    Fortinin, M.E.3    Artavanis-Tsakonas, S.4
  • 45
    • 0029982537 scopus 로고    scopus 로고
    • Genetic analysis of autoimmune disease
    • Vyse, T.J., and Todd, J.A. (1996). Genetic analysis of autoimmune disease. Cell 85, 311-318.
    • (1996) Cell , vol.85 , pp. 311-318
    • Vyse, T.J.1    Todd, J.A.2
  • 46
    • 0029838991 scopus 로고    scopus 로고
    • Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice
    • Wang, J., Koizumi, T., and Watanabe, T. (1996). Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice. J. Exp. Med. 184, 831-838.
    • (1996) J. Exp. Med. , vol.184 , pp. 831-838
    • Wang, J.1    Koizumi, T.2    Watanabe, T.3
  • 47
    • 0029847936 scopus 로고    scopus 로고
    • Evidence for a preformed transducer complex organized by the B cell antigen receptor
    • Wienands, J., Larbolette, O., and Reth, M. (1996). Evidence for a preformed transducer complex organized by the B cell antigen receptor. Proc. Natl. Acad. Sci. USA 93, 7865-7870.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7865-7870
    • Wienands, J.1    Larbolette, O.2    Reth, M.3
  • 48
    • 0025972582 scopus 로고
    • Association of B cell antigen receptor with protein tyrosine kinase Lyn
    • Yamanashi, Y., Kakiuchi, T., Mizuguchi, J., Yamamoto, T., and Toyoshima, K. (1991). Association of B cell antigen receptor with protein tyrosine kinase Lyn. Science 251, 192-194.
    • (1991) Science , vol.251 , pp. 192-194
    • Yamanashi, Y.1    Kakiuchi, T.2    Mizuguchi, J.3    Yamamoto, T.4    Toyoshima, K.5
  • 49
    • 0029124883 scopus 로고
    • Similarity of sli-1, a regulator of vulval development in C. Elegans, to the mammalian proto-oncogene c-cbl
    • Yoon, C.H., Lee, J., Jongeward, G.D., and Sternberg, P.W. (1995). Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian proto-oncogene c-cbl. Science 269, 1102-1105.
    • (1995) Science , vol.269 , pp. 1102-1105
    • Yoon, C.H.1    Lee, J.2    Jongeward, G.D.3    Sternberg, P.W.4


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