메뉴 건너뛰기




Volumn 163, Issue 4, 1999, Pages 1894-1905

The B cell antigen receptor activates the AKT (protein kinase B)/glycogen synthase kinase-3 signaling pathway via phosphatidylinositol 3- kinase

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE ANTIGEN; GLYCOGEN SYNTHASE KINASE 3; LYMPHOCYTE ANTIGEN RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; SERINE; THREONINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 0033566911     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (122)

References (89)
  • 1
    • 0028931028 scopus 로고
    • Signal transduction by the antigen receptors of B and T lymphocytes
    • Gold, M. R., and L. Matsuuchi. 1995. Signal transduction by the antigen receptors of B and T lymphocytes. Int. Rev. Cytol. 157:181.
    • (1995) Int. Rev. Cytol. , vol.157 , pp. 181
    • Gold, M.R.1    Matsuuchi, L.2
  • 2
    • 0031897046 scopus 로고    scopus 로고
    • Positive versus negative signaling by lymphocyte antigen receptors
    • Healy, J. I., and C. C. Goodnow. 1998. Positive versus negative signaling by lymphocyte antigen receptors. Anna. Rev. Immunol. 16:645.
    • (1998) Anna. Rev. Immunol. , vol.16 , pp. 645
    • Healy, J.I.1    Goodnow, C.C.2
  • 3
    • 0030831199 scopus 로고    scopus 로고
    • The complexity of signaling pathways activated by the BCR
    • DeFranco, A. L. 1997. The complexity of signaling pathways activated by the BCR. Curr. Opin. Immunol. 9:296.
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 296
    • DeFranco, A.L.1
  • 4
    • 0029882545 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase activation in normal human B lymphocytes: Differential sensitivity of growth and differentiation to wortmannin
    • Aagaard-Tillery, K. M., and D. F. Jelinek. 1996. Phosphatidylinositol 3-kinase activation in normal human B lymphocytes: differential sensitivity of growth and differentiation to wortmannin. J. Immunol. 156:4543.
    • (1996) J. Immunol. , vol.156 , pp. 4543
    • Aagaard-Tillery, K.M.1    Jelinek, D.F.2
  • 5
    • 0030068527 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-kinase activity is required for the anti-Ig-mediated growth inhibition of a human B-lymphoma cell line
    • Beckwith, M., R. G. Fenton, I. M. Katona, and D. L. Longo. 1996. Phosphatidylinositol-3-kinase activity is required for the anti-Ig-mediated growth inhibition of a human B-lymphoma cell line. Blood 87:202.
    • (1996) Blood , vol.87 , pp. 202
    • Beckwith, M.1    Fenton, R.G.2    Katona, I.M.3    Longo, D.L.4
  • 6
    • 0031006326 scopus 로고    scopus 로고
    • Regulatory recruitment of signaling molecules to the cell membrane by pleckstrin-homology domains
    • Lemmon, M. A., M. Falasca, K. M. Ferguson, and J. Schlessinger. 1997. Regulatory recruitment of signaling molecules to the cell membrane by pleckstrin-homology domains. Trends Cell Biol. 7:237.
    • (1997) Trends Cell Biol. , vol.7 , pp. 237
    • Lemmon, M.A.1    Falasca, M.2    Ferguson, K.M.3    Schlessinger, J.4
  • 7
    • 0032055485 scopus 로고    scopus 로고
    • SHIP modulates immune receptor responses by regulating membrane association of Btk
    • Bolland, S., R. N. Pearse, T. Kurosaki, and J. V. Ravetch. 1998. SHIP modulates immune receptor responses by regulating membrane association of Btk. Immunity 8:508.
    • (1998) Immunity , vol.8 , pp. 508
    • Bolland, S.1    Pearse, R.N.2    Kurosaki, T.3    Ravetch, J.V.4
  • 9
    • 0032055484 scopus 로고    scopus 로고
    • Phosphatidylinositol-3,4,5-trisphosphate (Ptdlns-3, 4, 5P,)/TEC kinase dependent calcium signaling pathway: A target for SHIP-mediated inhibitory signals
    • Scharenberg, A. M., O. El-Hillal, D. Fruman, Z. Li, L. Beitz, S. Lin, I. Gout, L. C. Cantley, D. J. Rawlings, and J. -P. Kinet. 1998. Phosphatidylinositol-3,4,5-trisphosphate (Ptdlns-3, 4, 5P,)/TEC kinase dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals. EMBO J. 127:1961.
    • (1998) EMBO J. , vol.127 , pp. 1961
    • Scharenberg, A.M.1    El-Hillal, O.2    Fruman, D.3    Li, Z.4    Beitz, L.5    Lin, S.6    Gout, I.7    Cantley, L.C.8    Rawlings, D.J.9    Kinet, J.-P.10
  • 11
    • 0032076954 scopus 로고    scopus 로고
    • CD19 as a membrane-anchored adaptor protein of B lymphocytes: Costimulation of lipid and protein kinases by recruitment of Vav
    • O'Rourke, L. M., R. Tooze, N. Turner, D. M. Sandoval, R. H. Carter, V. L. J. Tybulewicz, and D. T. Fearon. 1998. CD19 as a membrane-anchored adaptor protein of B lymphocytes: costimulation of lipid and protein kinases by recruitment of Vav. Immunity 8:635.
    • (1998) Immunity , vol.8 , pp. 635
    • O'Rourke, L.M.1    Tooze, R.2    Turner, N.3    Sandoval, D.M.4    Carter, R.H.5    Tybulewicz, V.L.J.6    Fearon, D.T.7
  • 12
    • 0028036684 scopus 로고
    • The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate-5-kinase in mammalian cells
    • Chong, L. D., A. Traynor-Kaplan, G. M. Bokoch, and M. A. Schwartz. 1994. The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate-5-kinase in mammalian cells. Cell 79:507.
    • (1994) Cell , vol.79 , pp. 507
    • Chong, L.D.1    Traynor-Kaplan, A.2    Bokoch, G.M.3    Schwartz, M.A.4
  • 13
    • 0029023942 scopus 로고
    • Rho family GTPases bind to phosphoinositide kinases
    • Tolias, K. F., L. C. Cantley, and C. L. Carpenter. 1995. Rho family GTPases bind to phosphoinositide kinases. J. Biol. Chem. 270:17656.
    • (1995) J. Biol. Chem. , vol.270 , pp. 17656
    • Tolias, K.F.1    Cantley, L.C.2    Carpenter, C.L.3
  • 14
    • 0030001638 scopus 로고    scopus 로고
    • Physical association of the small GTPase Rho with a 68-kDa phosphatidylinositol-4-phosphate-5-kinase in Swiss 3T3 cells
    • Ren, X. D., G. M. Bokoch, A. Traynor-Kaplan, G. H. Jenkins, R. A. Anderson, and M. A. Schwartz. 1996. Physical association of the small GTPase Rho with a 68-kDa phosphatidylinositol-4-phosphate-5-kinase in Swiss 3T3 cells. Mol. Biol. Cell 7:435.
    • (1996) Mol. Biol. Cell , vol.7 , pp. 435
    • Ren, X.D.1    Bokoch, G.M.2    Traynor-Kaplan, A.3    Jenkins, G.H.4    Anderson, R.A.5    Schwartz, M.A.6
  • 15
    • 0032559211 scopus 로고    scopus 로고
    • Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos
    • Nimnual, A. S., B. A. Yatsula, and D. Bar-Sagi. 1998. Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos. Science 279:560.
    • (1998) Science , vol.279 , pp. 560
    • Nimnual, A.S.1    Yatsula, B.A.2    Bar-Sagi, D.3
  • 16
  • 17
    • 0029079275 scopus 로고
    • The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
    • Franke, T. F., S. -I. Yang, T. O. Chan, K. Datta, A. Kazlauskas, D. K. Morrison, D. R. Kaplan, and P. N. Tsichlis. 1995. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81:727.
    • (1995) Cell , vol.81 , pp. 727
    • Franke, T.F.1    Yang, S.-I.2    Chan, T.O.3    Datta, K.4    Kazlauskas, A.5    Morrison, D.K.6    Kaplan, D.R.7    Tsichlis, P.N.8
  • 18
    • 0029143388 scopus 로고
    • Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing ser/thr kinase
    • Kohn, A. D., K. S. Kovacina, and R. A. Roth. 1995. Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing ser/thr kinase. EMBO J. 4288:4295.
    • (1995) EMBO J. , vol.4288 , pp. 4295
    • Kohn, A.D.1    Kovacina, K.S.2    Roth, R.A.3
  • 20
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated protein kinase B
    • Cross, D. A. E., D. R. Alessi, P. Cohen, M. Andjelkovic, and B. A. Hemmings. 1995. Inhibition of glycogen synthase kinase-3 by insulin mediated protein kinase B. Nature 378:785.
    • (1995) Nature , vol.378 , pp. 785
    • Cross, D.A.E.1    Alessi, D.R.2    Cohen, P.3    Andjelkovic, M.4    Hemmings, B.A.5
  • 21
    • 0029160069 scopus 로고
    • Protein kinase B (c-akt) in phosphatidylinositol 3-kinase signal transduction
    • Burgering, B. M. T., and P. J. Coffer. 1995. Protein kinase B (c-akt) in phosphatidylinositol 3-kinase signal transduction. Nature 376:599.
    • (1995) Nature , vol.376 , pp. 599
    • Burgering, B.M.T.1    Coffer, P.J.2
  • 22
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
    • del Peso, L., M. Gonzales-Garcia, C. Page, R. Herrera, and G. Nunez. 1997. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 278:687.
    • (1997) Science , vol.278 , pp. 687
    • Del Peso, L.1    Gonzales-Garcia, M.2    Page, C.3    Herrera, R.4    Nunez, G.5
  • 23
    • 0030908525 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 s6 kinase
    • Reif, K., B. M. T. Burgering, and D. A. Cantrell. 1997. Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase. J. Biol. Chem. 272:14426.
    • (1997) J. Biol. Chem. , vol.272 , pp. 14426
    • Reif, K.1    Burgering, B.M.T.2    Cantrell, D.A.3
  • 24
    • 0032560514 scopus 로고    scopus 로고
    • Dissociation of cytokine-induced phosphorylation of bad and activation of PKB/akt: Involvment of MEK upstream of BAD phosphorylation
    • Scheid, M. P., and V. Duronio. 1998. Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvment of MEK upstream of BAD phosphorylation. Proc. Natl. Acad. Sci. USA 95:7439.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7439
    • Scheid, M.P.1    Duronio, V.2
  • 25
    • 0029943605 scopus 로고    scopus 로고
    • Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal transducing kinase pathways
    • Klippel, A., C. Reinhard, W. M. Kavanaugh, G. Apell, M. A. Escobedo, and L. T. Williams. 1996. Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal transducing kinase pathways. Mol. Cell. Biol. 16:4117.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4117
    • Klippel, A.1    Reinhard, C.2    Kavanaugh, W.M.3    Apell, G.4    Escobedo, M.A.5    Williams, L.T.6
  • 26
    • 0032189381 scopus 로고    scopus 로고
    • Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation
    • Coffer, P. J., J. Jin, and J. R. Woodgett. 1998. Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem. J. 335:1.
    • (1998) Biochem. J. , vol.335 , pp. 1
    • Coffer, P.J.1    Jin, J.2    Woodgett, J.R.3
  • 27
    • 0030991386 scopus 로고    scopus 로고
    • High affinity binding of inosilol phosphates and phosphoinositides to the pleckstrin homology domain of RAC/protein kinase B and their influence on the kinase activity
    • Frech, M., M. Andjelkovic, E. Ingley, K. K. Reddy, J. R. Falck, and B. A. Hemmings. 1997. High affinity binding of inosilol phosphates and phosphoinositides to the pleckstrin homology domain of RAC/Protein kinase B and their influence on the kinase activity. J. Biol. Chem. 272:8474.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8474
    • Frech, M.1    Andjelkovic, M.2    Ingley, E.3    Reddy, K.K.4    Falck, J.R.5    Hemmings, B.A.6
  • 29
    • 0032079523 scopus 로고    scopus 로고
    • PKB and Rac are activated in parallel within a PI3-kinase controlled signalling pathway
    • Welch, H., A. Eguinoa, L. R. Stephens, and P. T. Hawkins. 1998. PKB and Rac are activated in parallel within a PI3-kinase controlled signalling pathway. J. Biol. Chem. 273:11248.
    • (1998) J. Biol. Chem. , vol.273 , pp. 11248
    • Welch, H.1    Eguinoa, A.2    Stephens, L.R.3    Hawkins, P.T.4
  • 31
    • 0031127305 scopus 로고    scopus 로고
    • Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
    • Alessi, D. R., S. R. James, C. P. Downes, A. B. Holmes, P. R. J. Gaffney, C. B. Reese, and P. Cohen. 1997. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα. Curr. Biol. 7:261.
    • (1997) Curr. Biol. , vol.7 , pp. 261
    • Alessi, D.R.1    James, S.R.2    Downes, C.P.3    Holmes, A.B.4    Gaffney, P.R.J.5    Reese, C.B.6    Cohen, P.7
  • 32
    • 0032482374 scopus 로고    scopus 로고
    • Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B
    • Anderson, K. E., J. Coadwell, L. R. Stephens, and P. T. Hawkins. 1998. Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B. Curr. Biol. 8:684.
    • (1998) Curr. Biol. , vol.8 , pp. 684
    • Anderson, K.E.1    Coadwell, J.2    Stephens, L.R.3    Hawkins, P.T.4
  • 33
    • 0032530482 scopus 로고    scopus 로고
    • Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase-3 and protein kinase B/Akt by the integrin-linked kinase
    • Delcommenne, M., C. Tan, V. Gray, L. Rue, J. Woodgett, and S. Dedhar. 1998. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase-3 and protein kinase B/Akt by the integrin-linked kinase. Proc. Natl. Acad. Sci. USA 95:11211.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 11211
    • Delcommenne, M.1    Tan, C.2    Gray, V.3    Rue, L.4    Woodgett, J.5    Dedhar, S.6
  • 34
    • 0028834557 scopus 로고
    • Role of phosphatidylinositol 3-OH-kinase activity in the inhibition of apoptosis in hemopoietic cells: Phosphatidylinositol 3-OH-kinase inhibitors reveal a difference in signaling between interleukin-3 and granulocyte-macrophage colony stimulating factor
    • Scheid, M. P., R. W. Lauener, and V. Duronio. 1995. Role of phosphatidylinositol 3-OH-kinase activity in the inhibition of apoptosis in hemopoietic cells: phosphatidylinositol 3-OH-kinase inhibitors reveal a difference in signaling between interleukin-3 and granulocyte-macrophage colony stimulating factor. Biochem. J. 312:159.
    • (1995) Biochem. J. , vol.312 , pp. 159
    • Scheid, M.P.1    Lauener, R.W.2    Duronio, V.3
  • 35
    • 0028963084 scopus 로고
    • Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor
    • Yao, R., and G. M. Cooper. 1995. Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. Science 267:2003.
    • (1995) Science , vol.267 , pp. 2003
    • Yao, R.1    Cooper, G.M.2
  • 36
    • 0030694175 scopus 로고    scopus 로고
    • Activated phosphtidylinositol 3-kinase and Akt promote survival of superior cervical neurons
    • Philpott, K. L., M. J. McCarthy, A. Klippel, and L. L. Rubin. 1997. Activated phosphtidylinositol 3-kinase and Akt promote survival of superior cervical neurons. J. Cell Biol. 139:809.
    • (1997) J. Cell Biol. , vol.139 , pp. 809
    • Philpott, K.L.1    McCarthy, M.J.2    Klippel, A.3    Rubin, L.L.4
  • 37
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: Downstream AKTion blocks apoptosis
    • Franke, T. F., D. R. Kaplan, and L. C. Cantley. 1997. PI3K: downstream AKTion blocks apoptosis. Cell 88:435.
    • (1997) Cell , vol.88 , pp. 435
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 38
    • 0031053360 scopus 로고    scopus 로고
    • Akt signaling: Linking membrane events to life and death decisions
    • Hemmings, B. A. 1997. Akt signaling: linking membrane events to life and death decisions. Science 275:628.
    • (1997) Science , vol.275 , pp. 628
    • Hemmings, B.A.1
  • 40
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta, S. R., H. Dudek, X. Tao, S. Masters, H. Fu, Y. Gotoh, and M. E. Greenberg. 1997. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91:231.
    • (1997) Cell , vol.91 , pp. 231
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 43
    • 0031433335 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F
    • Brennan, P., J. W. Babbage, B. M. T. Burgering, B. Groner, K. Reif, and D. A. Cantrell. 1997. Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F. Immunity 7:679.
    • (1997) Immunity , vol.7 , pp. 679
    • Brennan, P.1    Babbage, J.W.2    Burgering, B.M.T.3    Groner, B.4    Reif, K.5    Cantrell, D.A.6
  • 44
    • 0032520009 scopus 로고    scopus 로고
    • 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt (PKB) signaling pathway
    • Gingras, A. C., S. G. Kennedy, M. A. O'Leary, N. Sonenberg, and N. Hay. 1998. 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt (PKB) signaling pathway. Genes Dev. 12:502.
    • (1998) Genes Dev. , vol.12 , pp. 502
    • Gingras, A.C.1    Kennedy, S.G.2    O'Leary, M.A.3    Sonenberg, N.4    Hay, N.5
  • 45
    • 0031833563 scopus 로고    scopus 로고
    • Mammalian target of rapamycin: Immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling
    • Abraham, R. T. 1998. Mammalian target of rapamycin: immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling. Curr. Opin. Immunol. 10:330.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 330
    • Abraham, R.T.1
  • 46
    • 0028034233 scopus 로고
    • Insulin-dependent stimulation of protein synthesis by phosphorylalion of a regulator of 5′-cap function
    • Pause, A., G. J. Belsham, A. C. Gingras, O. Donze, T. A. Lin, J. C. Lawrence, and N. Sonenberg. 1994. Insulin-dependent stimulation of protein synthesis by phosphorylalion of a regulator of 5′-cap function. Nature 371:762.
    • (1994) Nature , vol.371 , pp. 762
    • Pause, A.1    Belsham, G.J.2    Gingras, A.C.3    Donze, O.4    Lin, T.A.5    Lawrence, J.C.6    Sonenberg, N.7
  • 47
    • 0032491579 scopus 로고    scopus 로고
    • Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway
    • Muise-Helmericks, R. C., H. L. Grimes, A. Bellacosa, S. E. Malstrom, P. N. Tsichlis, and N. Rosen. 1998. Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway. J. Biol. Chem. 273:29864.
    • (1998) J. Biol. Chem. , vol.273 , pp. 29864
    • Muise-Helmericks, R.C.1    Grimes, H.L.2    Bellacosa, A.3    Malstrom, S.E.4    Tsichlis, P.N.5    Rosen, N.6
  • 49
    • 16944366762 scopus 로고    scopus 로고
    • Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and β-adrenergic agonists in rat epididymal fat cells: Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms
    • Moule, S. K., G. I. Welsh, N. J. Edgell, E. J. Foulstone, C. G. Proud, and R. M. Denton. 1997. Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and β-adrenergic agonists in rat epididymal fat cells: activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms. J. Biol. Chem. 272:7713.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7713
    • Moule, S.K.1    Welsh, G.I.2    Edgell, N.J.3    Foulstone, E.J.4    Proud, C.G.5    Denton, R.M.6
  • 50
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family: Regulation and function
    • Rao, A., C. Luo, and P. G. Hogan. 1997. Transcription factors of the NFAT family: regulation and function. Annu. Rev. Immunol. 15:707.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 707
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 51
  • 52
    • 0031239961 scopus 로고    scopus 로고
    • Rapid targeting of nuclear proteins to the cytoplasm
    • Klemm, J. D., C. R. Beals, and G. R. Crabtree. 1997. Rapid targeting of nuclear proteins to the cytoplasm. Curr. Biol. 7:638.
    • (1997) Curr. Biol. , vol.7 , pp. 638
    • Klemm, J.D.1    Beals, C.R.2    Crabtree, G.R.3
  • 55
    • 0032498112 scopus 로고    scopus 로고
    • Regulation of eukaryotic inflation factor eIF2B: Glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin
    • Welsh, G. I., C. M. Miller, A. J. Loughlin, N. T. Price, and C. G. Proud. 1998. Regulation of eukaryotic inflation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin. FEBS Lett. 421:125.
    • (1998) FEBS Lett. , vol.421 , pp. 125
    • Welsh, G.I.1    Miller, C.M.2    Loughlin, A.J.3    Price, N.T.4    Proud, C.G.5
  • 56
    • 0032473355 scopus 로고    scopus 로고
    • Axin, a negative regulator of the wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin
    • Ikeda, S., S. Kishida, H. Yamamoto, H. Murai, S. Koyama, and A. Kikuchi. 1998. Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin. EMBO J. 17:1371.
    • (1998) EMBO J. , vol.17 , pp. 1371
    • Ikeda, S.1    Kishida, S.2    Yamamoto, H.3    Murai, H.4    Koyama, S.5    Kikuchi, A.6
  • 57
    • 0031836914 scopus 로고    scopus 로고
    • TCF: Transcriptional activator or repressor?
    • Bienz, M. 1998. TCF: transcriptional activator or repressor? Curr. Opin. Cell Biol. 10:366.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 366
    • Bienz, M.1
  • 58
    • 0032493729 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-kinase/Akt cell survival pathway
    • Pap, M., and G. M. Cooper. 1998. Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-kinase/Akt cell survival pathway. J. Biol. Chem. 273:19929.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19929
    • Pap, M.1    Cooper, G.M.2
  • 59
    • 0028002840 scopus 로고
    • Both phosphatidylinositol 3-kinase and phosphatidylinositol 4-kinase products are increased by antigen receptor signaling in B lymphocytes
    • Gold, M. R., and R. Aebersold. 1994. Both phosphatidylinositol 3-kinase and phosphatidylinositol 4-kinase products are increased by antigen receptor signaling in B lymphocytes. J. Immunol. 152:42.
    • (1994) J. Immunol. , vol.152 , pp. 42
    • Gold, M.R.1    Aebersold, R.2
  • 60
    • 0028926416 scopus 로고
    • Loss of surface immunoglobulin expression precedes B cell death by apoptosis in the bursa of Fabricius
    • Paramithiotis, E., K. A. Jacobsen, and M. J. H. Ratcliffe. 1995. Loss of surface immunoglobulin expression precedes B cell death by apoptosis in the bursa of Fabricius. J. Exp. Med. 181:105.
    • (1995) J. Exp. Med. , vol.181 , pp. 105
    • Paramithiotis, E.1    Jacobsen, K.A.2    Ratcliffe, M.J.H.3
  • 62
    • 0030018304 scopus 로고
    • A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-γ2
    • Takata, M., and T. Kurosaki. 1995. A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-γ2. J. Exp. Med. 184: 31.
    • (1995) J. Exp. Med. , vol.184 , pp. 31
    • Takata, M.1    Kurosaki, T.2
  • 63
    • 0028980409 scopus 로고
    • Requirement of phospholipase C-γ 2 activation in surface immunoglobulin M-induced B cell apoptosis
    • Takata, M., Y. Homma, and T. Kurosaki. 1995. Requirement of phospholipase C-γ 2 activation in surface immunoglobulin M-induced B cell apoptosis. J. Exp. Med. 182:907.
    • (1995) J. Exp. Med. , vol.182 , pp. 907
    • Takata, M.1    Homma, Y.2    Kurosaki, T.3
  • 64
    • 0027236954 scopus 로고
    • Production of high-titer helper-free retroviruses by transient transfection
    • Pear, W. S., G. P. Nolan, M. L. Scott, and D. Baltimore. 1993. Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA 90:8393.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8393
    • Pear, W.S.1    Nolan, G.P.2    Scott, M.L.3    Baltimore, D.4
  • 65
    • 0032837176 scopus 로고    scopus 로고
    • Rapid and efficient retrovirus-mediated gene transfer into B cell lines
    • In press
    • Krebs, D. L., Y. Yang, M. Dang, J. Haussmann, and M. R. Gold. 1999. Rapid and efficient retrovirus-mediated gene transfer into B cell lines. Meth. Cell Sci. In press.
    • (1999) Meth. Cell Sci.
    • Krebs, D.L.1    Yang, Y.2    Dang, M.3    Haussmann, J.4    Gold, M.R.5
  • 66
    • 0026539160 scopus 로고
    • The membrane IgM-associated proteins MB-1 and Ig-β are sufficient to promote surface expression of a partially functional B-cell antigen receptor in a nonlymphoid cell line
    • Matsuuchi, L., M. R. Gold, A. Travis, R. Grosschedl, A. L. DeFranco, and R. B. Kelly. 1992. The membrane IgM-associated proteins MB-1 and Ig-β are sufficient to promote surface expression of a partially functional B-cell antigen receptor in a nonlymphoid cell line. Proc. Natl. Acad. Sci. USA 89:3404.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 3404
    • Matsuuchi, L.1    Gold, M.R.2    Travis, A.3    Grosschedl, R.4    DeFranco, A.L.5    Kelly, R.B.6
  • 67
    • 0030003647 scopus 로고    scopus 로고
    • Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase
    • Richards, J. D., M. R. Gold, S. L. Hourihane, A. L. DeFranco, and L. Matsuuchi. 1996. Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase. J. Biol. Chem. 271:6458.
    • (1996) J. Biol. Chem. , vol.271 , pp. 6458
    • Richards, J.D.1    Gold, M.R.2    Hourihane, S.L.3    DeFranco, A.L.4    Matsuuchi, L.5
  • 68
    • 0032483540 scopus 로고    scopus 로고
    • mu-Opioid receptor activates signaling pathways implicated in cell survival and translational control
    • Polakiewicz, R. D., S. M. Schieferl, A. C. Gingras, and M. J. Comb. 1998. mu-Opioid receptor activates signaling pathways implicated in cell survival and translational control. J. Biol. Chem. 273:23534.
    • (1998) J. Biol. Chem. , vol.273 , pp. 23534
    • Polakiewicz, R.D.1    Schieferl, S.M.2    Gingras, A.C.3    Comb, M.J.4
  • 69
    • 0032510947 scopus 로고    scopus 로고
    • Insulin, but not contraction, activates Akt/PKB in isolated rat skeletal muscle
    • Brozinick, J. T., and M. J. Birnbaum. 1998. Insulin, but not contraction, activates Akt/PKB in isolated rat skeletal muscle. J. Biol. Chem. 273:14679.
    • (1998) J. Biol. Chem. , vol.273 , pp. 14679
    • Brozinick, J.T.1    Birnbaum, M.J.2
  • 70
    • 0032053709 scopus 로고    scopus 로고
    • Mechanisms and consequences of activation of protein kinase B/Akt
    • Downward, J. 1998. Mechanisms and consequences of activation of protein kinase B/Akt. Curr. Opin. Cell Biol. 10:262.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 262
    • Downward, J.1
  • 71
    • 0029118603 scopus 로고
    • Wortmannin as a unique probe for an intracellular signaling protein, phosphoinositide 3-kinase
    • Ui, M., T. Okada, K. Hazeki, and O. Hazeki. 1995. Wortmannin as a unique probe for an intracellular signaling protein, phosphoinositide 3-kinase. Trends Biochem. Sci. 20:303.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 303
    • Ui, M.1    Okada, T.2    Hazeki, K.3    Hazeki, O.4
  • 72
    • 0030795735 scopus 로고    scopus 로고
    • Molecular mechanisms in B cell antigen receptor signaling
    • Kurosaki, T. 1997. Molecular mechanisms in B cell antigen receptor signaling. Curr. Opin. Immunol. 9:309.
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 309
    • Kurosaki, T.1
  • 73
    • 0030890949 scopus 로고    scopus 로고
    • Initiation and processing of signals from the B cell antigen receptor
    • Reth, M., and J. Wienands. 1997. Initiation and processing of signals from the B cell antigen receptor. Annu. Rev. Immunol. 15:453.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 453
    • Reth, M.1    Wienands, J.2
  • 74
    • 0028840004 scopus 로고
    • Inactivation of glycogen synthase kinase-3 by epidermal growth factor is mediated by mitogen-activated protein kinase/p90 ribosomal protein s6 kinase signaling pathways in NIH/3T3 cells
    • Eldar-Finkelman, H., R. Seger, J. R. Vandenheede, and E. G. Krebs. 1995. Inactivation of glycogen synthase kinase-3 by epidermal growth factor is mediated by mitogen-activated protein kinase/p90 ribosomal protein S6 kinase signaling pathways in NIH/3T3 cells. J. Biol. Chem. 270:987.
    • (1995) J. Biol. Chem. , vol.270 , pp. 987
    • Eldar-Finkelman, H.1    Seger, R.2    Vandenheede, J.R.3    Krebs, E.G.4
  • 77
    • 0027169534 scopus 로고
    • CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase
    • Tuveson, D. A., R. H. Carter, S. P. Soltoff, and D. T. Fearon. 1993. CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase. Science 260:986.
    • (1993) Science , vol.260 , pp. 986
    • Tuveson, D.A.1    Carter, R.H.2    Soltoff, S.P.3    Fearon, D.T.4
  • 79
    • 0029671073 scopus 로고    scopus 로고
    • cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and She adaptors, and the p85 subunit of phosphatidylinositol 3-kinase
    • cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and She adaptors, and the p85 subunit of phosphatidylinositol 3-kinase. J. Biol. Chem. 271:3187.
    • (1996) J. Biol. Chem. , vol.271 , pp. 3187
    • Panchamoorthy, G.1    Fukazawa, T.2    Miyake, S.3    Soltoff, S.4    Reedquist, K.5    Druker, B.6    Shoelson, S.7    Cantley, L.8    Band, H.9
  • 80
    • 0032514897 scopus 로고    scopus 로고
    • The Gab1 protein is a docking site for multiple proteins involved in signaling by the B cell antigen receptor
    • Ingham, R. J., M. Holgado-Madruga, C. Siu, A. J. Wong, and M. R. Gold. 1998. The Gab1 protein is a docking site for multiple proteins involved in signaling by the B cell antigen receptor. J. Biol. Chem. 273:30630.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30630
    • Ingham, R.J.1    Holgado-Madruga, M.2    Siu, C.3    Wong, A.J.4    Gold, M.R.5
  • 83
    • 0028198388 scopus 로고
    • Activation of phosphatidylinositol-3′ kinase by Src-family kinase SH3 binding to the p85 subunit
    • Pleiman, C. M., W. M. Hertz, and J. C. Cambier. 1994. Activation of phosphatidylinositol-3′ kinase by Src-family kinase SH3 binding to the p85 subunit. Science 263:1609.
    • (1994) Science , vol.263 , pp. 1609
    • Pleiman, C.M.1    Hertz, W.M.2    Cambier, J.C.3
  • 86
    • 0032518467 scopus 로고    scopus 로고
    • 3-Phosphoinositide-dependent protein kinase I (PDK1) phosphorylates and activates the p70 s6 kinase in vivo and in vitro
    • Alessi, D. R., M. T. Kozlowski, Q. P. Weng, N. Morrice, and J. Avruch,. 1998. 3-phosphoinositide-dependent protein kinase I (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro. Curr. Biol. 8:69.
    • (1998) Curr. Biol. , vol.8 , pp. 69
    • Alessi, D.R.1    Kozlowski, M.T.2    Weng, Q.P.3    Morrice, N.4    Avruch, J.5
  • 87
    • 0033602281 scopus 로고    scopus 로고
    • Functional counterparts of mammalian protein kinases PDk1 and DGK in budding yeast
    • Casamayor, A., P. D. Torrance, T. Kobayashi, J. Thorner, and D. R. Alessi. 1999. Functional counterparts of mammalian protein kinases PDK1 and DGK in budding yeast. Curr. Biol. 9:186.
    • (1999) Curr. Biol. , vol.9 , pp. 186
    • Casamayor, A.1    Torrance, P.D.2    Kobayashi, T.3    Thorner, J.4    Alessi, D.R.5
  • 89
    • 0031255312 scopus 로고    scopus 로고
    • B cell receptor cross-linking prevents Fas-induced cell death by inactivating the IL-1β-converting enzyme protease and regulating Bcl-2/Bcl-x expression
    • Bras, A., C. Martinez-A., and E. Baixeras. 1997. B cell receptor cross-linking prevents Fas-induced cell death by inactivating the IL-1β-converting enzyme protease and regulating Bcl-2/Bcl-x expression. J. Immunol. 159:3168.
    • (1997) J. Immunol. , vol.159 , pp. 3168
    • Bras, A.1    Martinez-A, C.2    Baixeras, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.