메뉴 건너뛰기




Volumn 183, Issue 1, 2000, Pages 18-27

Multiple functions of p27(Kip1) and its alterations in tumor cells: A review

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER RESEARCH; CARCINOGENESIS; CELL ADHESION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; COLON CANCER; ENZYME REGULATION; HUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; REGULATORY MECHANISM;

EID: 0034011051     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(200004)183:1<18::AID-JCP3>3.0.CO;2-S     Document Type: Article
Times cited : (265)

References (132)
  • 2
    • 0030949419 scopus 로고    scopus 로고
    • Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells
    • Arber N, Doki Y, Han EK-H, Sgambato A, Zhou P, et al. 1997. Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells. Cancer Res 57:1569-1574.
    • (1997) Cancer Res , vol.57 , pp. 1569-1574
    • Arber, N.1    Doki, Y.2    Ek-H, H.3    Sgambato, A.4    Zhou, P.5
  • 3
    • 0032696891 scopus 로고    scopus 로고
    • Overexpressed cyclin D3 contributes to retaining the growth inhibitor p27 in the cytoplasm of thyroid tumor cells
    • Baldassarre G, Belletti B, Bruni P, Boccia A, Trapasso F, et al. 1999. Overexpressed cyclin D3 contributes to retaining the growth inhibitor p27 in the cytoplasm of thyroid tumor cells. J Clin Invest 104:865-874.
    • (1999) J Clin Invest , vol.104 , pp. 865-874
    • Baldassarre, G.1    Belletti, B.2    Bruni, P.3    Boccia, A.4    Trapasso, F.5
  • 4
    • 0032503572 scopus 로고    scopus 로고
    • Increased level of p21 in human ovarian tumors is associated with increased expression of CDK2, cyclin A and PCNA
    • Barboule N, Baldin V, Jozan S, Vidal S, Valette A. 1998. Increased level of p21 in human ovarian tumors is associated with increased expression of CDK2, cyclin A and PCNA. Int J Cancer 76:891-896.
    • (1998) Int J Cancer , vol.76 , pp. 891-896
    • Barboule, N.1    Baldin, V.2    Jozan, S.3    Vidal, S.4    Valette, A.5
  • 10
    • 0024429019 scopus 로고
    • Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation
    • Chen PL, Scully P, Shew JY. 1989. Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation. Cell 58:1193-1198.
    • (1989) Cell , vol.58 , pp. 1193-1198
    • Chen, P.L.1    Scully, P.2    Shew, J.Y.3
  • 15
    • 8244262438 scopus 로고    scopus 로고
    • Kip1 induces cell cycle arrest and loss of cyclin-Cdk activity in human breast cancer cells
    • Kip1 induces cell cycle arrest and loss of cyclin-Cdk activity in human breast cancer cells. Oncogene 14:2283-2289.
    • (1997) Oncogene , vol.14 , pp. 2283-2289
    • Craig, C.1    Wersto, R.2    Kim, M.3    Ohri, E.4    Li, Z.5
  • 18
  • 20
    • 0031026190 scopus 로고    scopus 로고
    • Accumulation of the p27/Kip1 cyclin-dependent kinase inhibitor and the timing of oligodendrocyte differentiation
    • Durand B, Gao FB, Raff M. 1997. Accumulation of the p27/Kip1 cyclin-dependent kinase inhibitor and the timing of oligodendrocyte differentiation. EMBO J 16:306-317.
    • (1997) EMBO J , vol.16 , pp. 306-317
    • Durand, B.1    Gao, F.B.2    Raff, M.3
  • 21
    • 0028075611 scopus 로고
    • Cdk inhibitors: On the threshold of checkpoints and development
    • Elledge SJ, Harper JW. 1994. Cdk inhibitors: on the threshold of checkpoints and development. Curr Opin Cell Biol 6:847-852.
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 847-852
    • Elledge, S.J.1    Harper, J.W.2
  • 22
    • 14444268041 scopus 로고    scopus 로고
    • Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer
    • Esposito V, Baldi A, De Luca A, Groger AM, Loda M, et al. 1997. Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer. Cancer Res 57:3381-3385.
    • (1997) Cancer Res , vol.57 , pp. 3381-3385
    • Esposito, V.1    Baldi, A.2    De Luca, A.3    Groger, A.M.4    Loda, M.5
  • 23
    • 0033580135 scopus 로고    scopus 로고
    • Kip1 induces drug resistance by preventing apotosis upstream of cytochrome c release and procaspase-3 activation in leukemic cells
    • Kip1 induces drug resistance by preventing apotosis upstream of cytochrome c release and procaspase-3 activation in leukemic cells. Oncogene 18:1411-1418.
    • (1999) Oncogene , vol.18 , pp. 1411-1418
    • Eymin, B.1    Haugg, M.2    Droin, N.3    Sordet, O.4    Dimanche-Boitrel, M.-T.5    Solary, E.6
  • 24
    • 0030027049 scopus 로고    scopus 로고
    • Dependence of cyclin E-CDK2 kinase activity on cell anchorage
    • Fang F, Orend G, Watanabe N, Hunter T, Ruoslahti E. 1996. Dependence of cyclin E-CDK2 kinase activity on cell anchorage. Science 271:499-502.
    • (1996) Science , vol.271 , pp. 499-502
    • Fang, F.1    Orend, G.2    Watanabe, N.3    Hunter, T.4    Ruoslahti, E.5
  • 33
    • 0028168242 scopus 로고
    • INK4B is a potential effector of TGF-β-induced cell cycle arrest
    • INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 371:257-261.
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 34
    • 0027496935 scopus 로고
    • The p21kd Cdk interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper JW, Adami G, Wei N, Keyomarsi K, Elledge SJ 1993. The p21kd Cdk interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 35
    • 0030611391 scopus 로고    scopus 로고
    • Kip1 in gamma interferon-mediated growth arrest of mammary epithelial cells and related defects in mammary carcinoma cells
    • Kip1 in gamma interferon-mediated growth arrest of mammary epithelial cells and related defects in mammary carcinoma cells. Oncogene 14-2111-2122.
    • (1997) Oncogene , vol.14 , pp. 2111-2122
    • Harvat, B.L.1    Seth, P.2    Jetten, A.M.3
  • 36
    • 0031750613 scopus 로고    scopus 로고
    • Ink4a is associated with, but not sufficient for, induction of squamous differentiation
    • Ink4a is associated with, but not sufficient for, induction of squamous differentiation. J Cell Sci 1111:1185-1196.
    • (1998) J Cell Sci , vol.1111 , pp. 1185-1196
    • Harvat, B.L.1    Wang, A.2    Seth, P.3    Jetten, A.M.4
  • 38
    • 0029670477 scopus 로고    scopus 로고
    • Kip1 accumulation during the cell cycle
    • Kip1 accumulation during the cell cycle. Science 271:1861-1864.
    • (1996) Science , vol.271 , pp. 1861-1864
    • Hengst, L.1    Reed, S.I.2
  • 40
    • 0026802989 scopus 로고
    • Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
    • Hinds PW, Mittnacht S, Dulic V, Arnold A, Reed SI, Weinberg RA. 1992. Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell 70:993-1006.
    • (1992) Cell , vol.70 , pp. 993-1006
    • Hinds, P.W.1    Mittnacht, S.2    Dulic, V.3    Arnold, A.4    Reed, S.I.5    Weinberg, R.A.6
  • 41
    • 0028918388 scopus 로고
    • Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6
    • Hirai H, Roussel MF, Kato J, Ashmun RA, Sherr CJ. 1995. Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6. Mol Cell Biol 15:2672-2681.
    • (1995) Mol Cell Biol , vol.15 , pp. 2672-2681
    • Hirai, H.1    Roussel, M.F.2    Kato, J.3    Ashmun, R.A.4    Sherr, C.J.5
  • 43
    • 0033525188 scopus 로고    scopus 로고
    • Kip1 degradation through its regulation of cyclin E/CDK2 activity
    • Kip1 degradation through its regulation of cyclin E/CDK2 activity. J Biol Chem 274:3396-3401.
    • (1999) J Biol Chem , vol.274 , pp. 3396-3401
    • Hu, W.1    Bellone, C.J.2    Baldassare, J.J.3
  • 44
    • 0027938209 scopus 로고
    • Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
    • Hunter T, Pines J. 1994. Cyclins and cancer II: cyclin D and CDK inhibitors come of age. Cell 79:573-582.
    • (1994) Cell , vol.79 , pp. 573-582
    • Hunter, T.1    Pines, J.2
  • 45
    • 0030758940 scopus 로고    scopus 로고
    • Molecular analysis of p21 and p27 genes in human pituitary adenomas
    • Ikeda H, Yoshimoto T, Shida N. 1997. Molecular analysis of p21 and p27 genes in human pituitary adenomas. Br J Cancer 76:1119-1123.
    • (1997) Br J Cancer , vol.76 , pp. 1119-1123
    • Ikeda, H.1    Yoshimoto, T.2    Shida, N.3
  • 47
    • 0032537022 scopus 로고    scopus 로고
    • Expression of the v-Src oncoprotein in fibroblasts disrupts normal regulation of the CDK inhibitor p27 and inhibits quiescence
    • Johnson D, Frame MC, Wyke JA. 1998. Expression of the v-Src oncoprotein in fibroblasts disrupts normal regulation of the CDK inhibitor p27 and inhibits quiescence. Oncogene 16:2017-2028.
    • (1998) Oncogene , vol.16 , pp. 2017-2028
    • Johnson, D.1    Frame, M.C.2    Wyke, J.A.3
  • 50
    • 0031439355 scopus 로고    scopus 로고
    • Promoting apoptosis: A novel activity associated with the cyclin-dependent kinase inhibitor p27
    • Katayose Y, Kim M, Rakkar ANS, Li Z, Cowan KH, Seth P. 1997. Promoting apoptosis: a novel activity associated with the cyclin-dependent kinase inhibitor p27. Cancer Res 57:5441-5445.
    • (1997) Cancer Res , vol.57 , pp. 5441-5445
    • Katayose, Y.1    Kim, M.2    Rakkar, A.N.S.3    Li, Z.4    Cowan, K.H.5    Seth, P.6
  • 53
    • 0029007867 scopus 로고
    • Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies
    • Kawamata N, Morosetti R, Miller CW, Park D, Spirin KS, et al. 1995. Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies. Cancer Res 55:2266-2269.
    • (1995) Cancer Res , vol.55 , pp. 2266-2269
    • Kawamata, N.1    Morosetti, R.2    Miller, C.W.3    Park, D.4    Spirin, K.S.5
  • 54
    • 0031596172 scopus 로고    scopus 로고
    • Kip1 and cyclin-dependent kinase 2 in the proliferation of non-small cell lung cancer
    • Kip1 and cyclin-dependent kinase 2 in the proliferation of non-small cell lung cancer. Am J Pathol 153:505-513.
    • (1998) Am J Pathol , vol.153 , pp. 505-513
    • Kawana, H.1    Tamaru, J.2    Tanaka, T.3    Hirai, A.4    Saito, Y.5
  • 56
    • 0033600160 scopus 로고    scopus 로고
    • Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1
    • Kortylewski M, Heinrich PC, Mackiewicz A, Schniertshauer U, Klingmuller U, et al. 1999. Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1. Oncogene 18:3742-3753.
    • (1999) Oncogene , vol.18 , pp. 3742-3753
    • Kortylewski, M.1    Heinrich, P.C.2    Mackiewicz, A.3    Schniertshauer, U.4    Klingmuller, U.5
  • 57
    • 0029133503 scopus 로고
    • Inhibition of cyclin-dependent kinase triggers neuronal differentiation of mouse neuroblastoma cells
    • Kranenburg O, Scharnhorst V, van der Eb AJ, Zantema A. 1995. Inhibition of cyclin-dependent kinase triggers neuronal differentiation of mouse neuroblastoma cells. J Cell Biol 131:227-234.
    • (1995) J Cell Biol , vol.131 , pp. 227-234
    • Kranenburg, O.1    Scharnhorst, V.2    Van Der Eb, A.J.3    Zantema, A.4
  • 59
    • 0028988158 scopus 로고
    • KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
    • KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev 9:639-649.
    • (1995) Genes Dev , vol.9 , pp. 639-649
    • Lee, M.1    Reynisdottir, I.2    Massague, J.3
  • 60
    • 0033611586 scopus 로고    scopus 로고
    • p27 is involved in N-cadherin-mediated contact inhibition of cell growth and S-phase entry
    • Levenberg S, Yarden A, Kam Z, Geiger B. 1999. p27 is involved in N-cadherin-mediated contact inhibition of cell growth and S-phase entry. Oncogene 18:869-876.
    • (1999) Oncogene , vol.18 , pp. 869-876
    • Levenberg, S.1    Yarden, A.2    Kam, Z.3    Geiger, B.4
  • 61
    • 0032431028 scopus 로고    scopus 로고
    • PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells
    • Li D-M, Sun H. 1998. PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells. Proc Natl Acad Sci USA 95:15406-15411.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15406-15411
    • Li, D.-M.1    Sun, H.2
  • 62
    • 0030065422 scopus 로고    scopus 로고
    • Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937
    • Liu M, Lee M, Cohen M, Bommakanti M, Freedman LP. 1996. Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. Genes Dev 10:142-153.
    • (1996) Genes Dev , vol.10 , pp. 142-153
    • Liu, M.1    Lee, M.2    Cohen, M.3    Bommakanti, M.4    Freedman, L.P.5
  • 64
    • 0032587495 scopus 로고    scopus 로고
    • Kip1: A multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers
    • Kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers. Am J Pathol 154:313-323.
    • (1999) Am J Pathol , vol.154 , pp. 313-323
    • Lloyd, R.V.1    Erickson, L.A.2    Jin, L.3    Kulig, E.4    Qian, X.5
  • 65
    • 0031048236 scopus 로고    scopus 로고
    • Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
    • Loda M, Cukor B, Tam SW, Lavin P, Fiorentino M, et al. 1997. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat Med 3:231-233.
    • (1997) Nat Med , vol.3 , pp. 231-233
    • Loda, M.1    Cukor, B.2    Tam, S.W.3    Lavin, P.4    Fiorentino, M.5
  • 66
    • 0033594395 scopus 로고    scopus 로고
    • Cyclin E dependent kinase activity in human breast cancer in relation to cyclin E, p27 and p21 expression and retinoblastoma protein phosphorylation
    • Lod́en M, Nielsen NH, Roos G, Emdin SO, Landberg G. 1999. Cyclin E dependent kinase activity in human breast cancer in relation to cyclin E, p27 and p21 expression and retinoblastoma protein phosphorylation. Oncogene 18:2557-2566.
    • (1999) Oncogene , vol.18 , pp. 2557-2566
    • Lod́en, M.1    Nielsen, N.H.2    Roos, G.3    Emdin, S.O.4    Landberg, G.5
  • 67
    • 0028880855 scopus 로고
    • Cyclins, cyclin-dependent kinases and Cdk inhibitors: Implications in cell cycle control and cancer
    • MacLachlan TK, Sang N, Giordano A. 1995. Cyclins, cyclin-dependent kinases and Cdk inhibitors: implications in cell cycle control and cancer. Crit Rev Eukaryot Gene Expr 5:127-156.
    • (1995) Crit Rev Eukaryot Gene Expr , vol.5 , pp. 127-156
    • MacLachlan, T.K.1    Sang, N.2    Giordano, A.3
  • 69
    • 0001208875 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor p27 as a mediator of the G1-S phase block induced by 1,25-Dihydroxyvitamin D3 in HL60 cells
    • Mang QM, Jones JB, Studzinski GP. 1996. Cyclin-dependent kinase inhibitor p27 as a mediator of the G1-S phase block induced by 1,25-Dihydroxyvitamin D3 in HL60 cells. Cancer Res 56:264-267.
    • (1996) Cancer Res , vol.56 , pp. 264-267
    • Mang, Q.M.1    Jones, J.B.2    Studzinski, G.P.3
  • 70
    • 17444427662 scopus 로고    scopus 로고
    • Frequent loss of expression of the cyclin-dependent kinase inhibitor p27 in epithelial ovarian cancer
    • Masciullo V, Sgambato A, Pacilio C, Pucci B, Ferrandina G, et al. 1999. Frequent loss of expression of the cyclin-dependent kinase inhibitor p27 in epithelial ovarian cancer. Cancer Res 59:3790-3794.
    • (1999) Cancer Res , vol.59 , pp. 3790-3794
    • Masciullo, V.1    Sgambato, A.2    Pacilio, C.3    Pucci, B.4    Ferrandina, G.5
  • 71
    • 0032547894 scopus 로고    scopus 로고
    • Kip1 in cell cycle arrest after androgen depletion in mouse mammary carcinoma cells (SC-3)
    • Kip1 in cell cycle arrest after androgen depletion in mouse mammary carcinoma cells (SC-3). Oncogene 17:2619-2627.
    • (1998) Oncogene , vol.17 , pp. 2619-2627
    • Menjo, M.1    Kaneko, Y.2    Ogata, E.3    Ikeda, K.4    Nakanishi, M.5
  • 72
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan DO. 1995. Principles of CDK regulation. Nature 374:131-134.
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 76
    • 0030010591 scopus 로고    scopus 로고
    • Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
    • Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85:707-720.
    • (1996) Cell , vol.85 , pp. 707-720
    • Nakayama, K.1    Ishida, N.2    Shirane, M.3    Inomata, A.4    Inoue, T.5
  • 78
    • 0032905150 scopus 로고    scopus 로고
    • Kip1, a G1-cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome
    • Kip1, a G1-cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome. Mol Cell Biol 19:1190-1201.
    • (1999) Mol Cell Biol , vol.19 , pp. 1190-1201
    • Nguyen, H.1    Gitig, D.M.2    Koff, A.3
  • 82
    • 0029024015 scopus 로고
    • Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
    • Pagano M, Tam SW, Theodoras AM, Beer-Romero P, Del Sal G, et al. 1995. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 269:682-685.
    • (1995) Science , vol.269 , pp. 682-685
    • Pagano, M.1    Tam, S.W.2    Theodoras, A.M.3    Beer-Romero, P.4    Del Sal, G.5
  • 84
    • 0028986931 scopus 로고
    • Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias
    • Pietenpol JA, Bohlander SK, Sato Y, Papadopoulos N, Liu B, et al. 1995. Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias. Cancer Res 55:1206-1210.
    • (1995) Cancer Res , vol.55 , pp. 1206-1210
    • Pietenpol, J.A.1    Bohlander, S.K.2    Sato, Y.3    Papadopoulos, N.4    Liu, B.5
  • 86
    • 0028179669 scopus 로고
    • KIP1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest
    • KIP1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev 8:9-22.
    • (1994) Genes Dev , vol.8 , pp. 9-22
    • Polyak, K.1    Kato, J.-Y.2    Solomon, M.J.3    Sherr, C.J.4    Massague, J.5
  • 87
    • 0028176483 scopus 로고
    • KIP1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
    • KIP1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78:59-66.
    • (1994) Cell , vol.78 , pp. 59-66
    • Polyak, K.1    Lee, M.-H.2    Erdjument-Bromage, A.3    Koff, A.4    Roberts, J.M.5
  • 89
    • 0031048716 scopus 로고    scopus 로고
    • Expression of cell-cycle regulators p27 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients
    • Porter PL, Malone KE, Heagerty PJ, Alexander GM, Gatti LA, et al. 1997. Expression of cell-cycle regulators p27 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. Nat Med 3:222-225.
    • (1997) Nat Med , vol.3 , pp. 222-225
    • Porter, P.L.1    Malone, K.E.2    Heagerty, P.J.3    Alexander, G.M.4    Gatti, L.A.5
  • 91
    • 0031985094 scopus 로고    scopus 로고
    • Activated Raf-1 causes growth arrest in human small cell lung cancer cells
    • Ravi RK, Weber E, McMahon M, Williams JR, Baylin S, et al. 1998. Activated Raf-1 causes growth arrest in human small cell lung cancer cells. J Clin Invest 101:153-159.
    • (1998) J Clin Invest , vol.101 , pp. 153-159
    • Ravi, R.K.1    Weber, E.2    McMahon, M.3    Williams, J.R.4    Baylin, S.5
  • 92
    • 0029153609 scopus 로고
    • Kip/Cip and INK4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β
    • Reynisdottir I, Polyak K, Iavarone A, Massague J. 1995. Kip/Cip and INK4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev 9:1831-1845.
    • (1995) Genes Dev , vol.9 , pp. 1831-1845
    • Reynisdottir, I.1    Polyak, K.2    Iavarone, A.3    Massague, J.4
  • 96
    • 0033522231 scopus 로고    scopus 로고
    • KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity
    • KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity. Oncogene 18:1663-1676.
    • (1999) Oncogene , vol.18 , pp. 1663-1676
    • Schreiber, M.1    Muller, W.J.2    Singh, G.3    Graham, F.L.4
  • 97
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D. 1993. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 366:704-707.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 102
    • 0033153763 scopus 로고    scopus 로고
    • Kip1 expression correlates with tumor grade and with reduced disease-free survival in primary superficial bladder cancers
    • Kip1 expression correlates with tumor grade and with reduced disease-free survival in primary superficial bladder cancers. Cancer Res 59:3245-3250.
    • (1999) Cancer Res , vol.59 , pp. 3245-3250
    • Sgambato, A.1    Migaldi, M.2    Faraglia, B.3    Garagnani, L.4    Romano, G.5
  • 105
    • 0028171292 scopus 로고
    • G1 phase progression: Cycling on cue
    • Sherr CJ. 1994. G1 phase progression: cycling on cue. Cell 79:551-555.
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.J.1
  • 106
  • 107
    • 0028988585 scopus 로고
    • Inhibitors of mammalian G1 cyclin-dependent kinases
    • Sherr CJ, Roberts JM. 1995. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 9:1149-1163.
    • (1995) Genes Dev , vol.9 , pp. 1149-1163
    • Sherr, C.J.1    Roberts, J.M.2
  • 108
    • 0027940495 scopus 로고
    • Absence of WAF1 mutations in a variety of human malignancies
    • Shiohara M, El-Deiry WS, Wada M, Nakamaki T, Takeuchi S, et al. 1994. Absence of WAF1 mutations in a variety of human malignancies. Blood 84:3781-3784.
    • (1994) Blood , vol.84 , pp. 3781-3784
    • Shiohara, M.1    El-Deiry, W.S.2    Wada, M.3    Nakamaki, T.4    Takeuchi, S.5
  • 109
    • 0032522414 scopus 로고    scopus 로고
    • Loss or altered subcellular localization of p27 in Barrett's associated adenocarcinomas
    • Singh SP, Lipman J, Goldman H, Ellis FH, Aizenman L, et al. 1998. Loss or altered subcellular localization of p27 in Barrett's associated adenocarcinomas. Cancer Res 58:1730-1735.
    • (1998) Cancer Res , vol.58 , pp. 1730-1735
    • Singh, S.P.1    Lipman, J.2    Goldman, H.3    Ellis, F.H.4    Aizenman, L.5
  • 110
    • 0032430241 scopus 로고    scopus 로고
    • Inactivation of the cyclin-dependent kinase inhibitor p27 upon loss of the tuberous sclerosis complex gene-2
    • Soucek T, Yeung RS, Hengstschlager M. 1998. Inactivation of the cyclin-dependent kinase inhibitor p27 upon loss of the tuberous sclerosis complex gene-2. Proc Natl Acad Sci USA 95:15653-15658.
    • (1998) Proc Natl Acad Sci Usa , vol.95 , pp. 15653-15658
    • Soucek, T.1    Yeung, R.S.2    Hengstschlager, M.3
  • 111
    • 0029094329 scopus 로고
    • Identification of a myc-dependent step during the formation of active G1 cyclin-cdk complexes
    • Steiner P, Philipp A, Lukas J, Godden-Kent D, Pagano M, et al. 1995. Identification of a myc-dependent step during the formation of active G1 cyclin-cdk complexes. EMBO J 14:4814-4826.
    • (1995) EMBO J , vol.14 , pp. 4814-4826
    • Steiner, P.1    Philipp, A.2    Lukas, J.3    Godden-Kent, D.4    Pagano, M.5
  • 112
    • 0030740210 scopus 로고    scopus 로고
    • Kip1 downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts
    • Kip1 downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts. Mol Cell Biol 17:5348-5358.
    • (1997) Mol Cell Biol , vol.17 , pp. 5348-5358
    • Takuwa, N.1    Takuwa, Y.2
  • 113
    • 0030894787 scopus 로고    scopus 로고
    • The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a, b) invasive breast carcinomas
    • Tan P, Cady B, Wanner M, Worland P, Cukor B, et al. 1997. The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a, b) invasive breast carcinomas. Cancer Res 57:1259-1263.
    • (1997) Cancer Res , vol.57 , pp. 1259-1263
    • Tan, P.1    Cady, B.2    Wanner, M.3    Worland, P.4    Cukor, B.5
  • 114
    • 0031689717 scopus 로고    scopus 로고
    • Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases
    • Thomas GV, Szigeti K, Murphy M, Draetta G, Pagano M, Loda M. 1998. Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases. Am J Pathol 153:681-687.
    • (1998) Am J Pathol , vol.153 , pp. 681-687
    • Thomas, G.V.1    Szigeti, K.2    Murphy, M.3    Draetta, G.4    Pagano, M.5    Loda, M.6
  • 117
    • 0031667133 scopus 로고    scopus 로고
    • Kip1, an inhibitor of G1 cyclin-dependent kinases, uncouple differentiation and growth arrest during the granulosa → luteal transition
    • Kip1, an inhibitor of G1 cyclin-dependent kinases, uncouple differentiation and growth arrest during the granulosa → luteal transition. Cell Growth Differ 9:787-794.
    • (1998) Cell Growth Differ , vol.9 , pp. 787-794
    • Tong, W.1    Kiyokawa, H.2    Soos, T.J.3    Park, M.S.4    Scares, V.C.5
  • 118
    • 0028363519 scopus 로고
    • P27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
    • Toyoshima H, Hunter T. 1994. P27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78:67-74.
    • (1994) Cell , vol.78 , pp. 67-74
    • Toyoshima, H.1    Hunter, T.2
  • 122
    • 0030847760 scopus 로고    scopus 로고
    • Phosphorylation-dependent degradation of the cyclin-dependent inhibitor p27
    • Vlach J, Hennecke S, Amati B. 1997. Phosphorylation-dependent degradation of the cyclin-dependent inhibitor p27. EMBO J 16:5334-5344.
    • (1997) EMBO J , vol.16 , pp. 5334-5344
    • Vlach, J.1    Hennecke, S.2    Amati, B.3
  • 126
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg RA. 1995. The retinoblastoma protein and cell cycle control. Cell 81:323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 127
    • 0000852361 scopus 로고    scopus 로고
    • Cell cycle control gene defects and human cancers
    • Bertino Jr, Editor . New York: Academic
    • Weinstein IB, Zhou P. 1997. Cell cycle control gene defects and human cancers. In: Bertino JR, editor. Encyclopedia of cancer, Vol. 1. New York: Academic. p 256-267.
    • (1997) Encyclopedia of Cancer , vol.1 , pp. 256-267
    • Weinstein, I.B.1    Zhou, P.2
  • 132
    • 0033233430 scopus 로고    scopus 로고
    • Kip1 in the promyelocytic leukemia cell line HL60 accelerates its lineage-specific differentiation
    • in press
    • Kip1 in the promyelocytic leukemia cell line HL60 accelerates its lineage-specific differentiation. Anticancer Res (in press).
    • (1999) Anticancer Res
    • Zhou, P.1    Yao, Y.2    Soh, J.-W.3    Weinstein, I.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.