Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1

Oncogene

Volumn 18, Issue 25, 1999, Pages 3742-3753

  Kortylewski, Marcin ^a,b   Heinrich, Peter C ^a   Mackiewicz, Andrzej ^b   Schniertshauer, Ute ^a   Klingmüller, Ursula ^c   Nakajima, Koichi ^d   Hirano, Toshio ^d   Horn, Friedemann ^e   Behrmann, Iris ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^c MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^d OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^e UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Growth arrest; Interleukin 6; Melanoma; Oncostatin M; p27 Kip; STAT

Indexed keywords

GLYCOPROTEIN GP 130; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; MESSENGER RNA; ONCOSTATIN M; PROTEIN P27; RETINOBLASTOMA PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN; TYROSINE;

ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MELANOMA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANTIGENS, CD; CELL CYCLE PROTEINS; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYTOKINE RECEPTOR GP130; DNA-BINDING PROTEINS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MELANOMA; MEMBRANE GLYCOPROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; ONCOSTATIN M; PEPTIDES; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, ERYTHROPOIETIN; RECOMBINANT FUSION PROTEINS; RETINOBLASTOMA PROTEIN; RNA, MESSENGER; RNA, NEOPLASM; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0033600160     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202708     Document Type: Article

References (56)

1. Arcone R, Pucci P, Zappacosta F, Fontaine V, Malorni A, Marino G and Ciliberto G. (1991). Eur. J. Biochem., 198, 541-547.
2. Bellido T, O'Brien CA, Roberson PK and Manolagas SC. (1998). J. Biol. Chem., 273, 21137-21144.
3. Boeuf H, Hauss C, De Graeve F, Baran N and Kedinger C. (1997). J. Cell. Biol., 138, 1207-1217.
4. Boulton TG, Stahl N and Yancopoulos GD. (1994). J. Biol. Chem., 269, 11648-11655.
5. Casagrande F, Bacqueville D, Pillaire MJ, Malecaze F, Manenti S, Breton-Douillon M and Darbon JM. (1998). FEBS Lett., 422, 385-390.
6. Chen L, Mory Y, Zilberstein A and Revel M. (1988). Proc. Natl. Acad. Sci. USA, 85, 8037-8041.
7. Dittrich E, Renfrew Haft C, Muys L, Heinrich PC and Graeve L. (1996). J. Biol. Chem. 271, 5487-5494.
8. Douglas AM, Goss GA, Sutherland RL, Hilton DJ, Berndt MC, Nicola NA and Begley CG. (1997). Oncogene, 14, 661-669.
9. Ernst M, Gearing DP and Dunn AR. (1994). EMBO J., 13, 1574-1584.
10. Florenes VA, MacIandsmo GM, Kerbel RS, Slingerland JM, Nesland JM and Holm R. (1998). Am. J. Pathol., 153, 305-312.
11. Frangioni JV and Neel BG. (1993). Anal. Biochem., 210, 179-187.
12. Fukada T, Hibi M. Yamanaka Y, Takahashi-Tezuka M, Fujitani Y, Yamaguchi T, Nakajima K and Hirano T. (1996). Immunity, 5, 449-460.
13. Fukada T, Ohtani T, Yoshida Y, Shirogane T, Nishida K, Nakajima K, Hibi M and Hirano T. (1998). EMBO J., 17, 6670-6677.
14. Ganapathi MK, Weizer AK, Borsellino, S, Bukowski RM, Ganapathi R, Rice T, Casey G and Kawamura K. (1996). Cell Growth Differ., 7, 923-929.
15. Gearing DP, Comeau MR, Friend DJ, Gimpel SD, Thut CJ, McGourty J, Brasher KK, King JA, Gillis S, Mosley B, Ziegler SF and Cosman D. (1992). Science, 255, 1434-1437.
16. Gerhartz C, Heesel B, Sasse J, Hemmann U, Landgraf C, Schneider-Mergener J, Horn F, Heinrich PC and Graeve L. (1996). J. Biol. Chem., 271, 12991-12998.
17. Heinrich PC, Behrmann I, Müller-Newen G, Schaper F and Graeve L. (1998). Biochem. J., 334, 297-314.
18. Herlyn M. (1990). Cancer and Metastasis Rev., 9, 101-112.
19. Hirano T. (1998). Int. Rev. Immunol., 16, 249-284.
20. Horn D, Fitzpatrick WC, Gompper PT, Ochs V, Bolton-Hansen M, Zarling J, Malik N, Todaro GJ and Linsley PS. (1990). Growth Factors, 2, 157-165.
21. Ihara S, Nakajima K, Fukada T, Hibi M, Nagata S, Hirano T and Fukui Y. (1997). EMBO J., 16, 5345-5352.
22. Kim H, Hawley TS, Hawley RG and Baumann H. (1998). Mol. Cell. Biol., 18, 1525-1533.
23. Kumar G, Gupta S, Wang S and Nel, AE. (1994). J. Immunol., 153, 4436-4447.
24. Lee IS, Liu Y, Narazaki M, Hibi M, Kishimoto T and Taga T. (1997). FEBS Lett., 401, 133-137.
25. Lu C, Vickers MF and Kerbel RS. (1992). Proc. Natl. Acad. Sci. USA, 89, 9215-9219.
26. Lu C, Rak JW, Kobayashi H and Kerbel RS. (1993). Cancer Res., 53, 2708-2711.
27. Lu C, Sheehan C, Rak JW, Chambers CA, Hozumi N and Kerbel RS. (1996). Clin. Cancer Res., 2, 1417-1425.
28. Mackiewicz A, Schooltink H, Heinrich PC and Rose-John S. (1992). J. Immunol., 149, 2021-2027.
29. Manenti S, Malecaze F, Chap H and Darbon JM. (1998). Cancer Res., 58, 1429-1434.
30. Matsuda T, Fukada T, Takahashi-Tezuka M, Okuyama Y, Fujitani Y, Hanazono Y, Hirai H and Hirano T. (1995a). J. Biol. Chem., 270, 11037-11039.
31. Matsuda T, Takahashi-Tezuka M, Fukada T, Okuyama Y, Fujitani Y, Tsukada S, Mano H, Hirai H, Witte ON and Hirano T. (1995b). Blood, 85, 627-633.
32. May P, Gerhartz C, Heesel B, Welte T, Doppler W, Graeve L, Horn F and Heinrich PC. (1996). FEBS. Lett., 394, 221-226.
33. Minami M, Inoue M, Wei S, Takeda K, Matsumoto M, Kishimoto T and Akira S. (1996). Proc. Natl. Acad. Sci. USA, 93, 3963-3966,
34. Morinaga Y, Suzuki H, Takatsuki F, Akiyama Y, Taniyama T, Matsushima K and Onozaki K. (1989). J. Immunol., 143, 3538-3542.
35. Morse L, Chen D, Franklin D, Xiong Y and Chen-Kiang S. (1997). Immunity, 6, 47-56.
36. Mosley B, De Imus C, Friend D, Boiani N, Thoma B, Park LS and Cosman D. (1996). J. Biol. Chem., 271, 32635-32643.
37. Murakami M, Narazaki M, Hibi M, Yawata H, Yasukawa K, Hamaguchi M, Taga T and Kishimoto T. (1991). Proc. Natl. Acad. Sci. USA, 88, 11349-11353.
38. Nakajima K, Yamanaka Y, Nakae K, Kojima H, Ichiba M, Kiuchi N, Kitaoka T, Fukada T, Hibi M and Hirano T. (1996). EMBO J., 15, 3651-3658.
39. Narimatsu M, Nakajima K, Ichiba M and Hirano T. (1997). Biochem. Biophys. Res. Commun., 238, 764-768.
40. Niwa H, Burdon T, Chambers I and Smith A. (1998). Genes Dev., 12, 2048-2060.
41. Oh J-W, Katz A, Harroch S, Eisenbach L, Revel M and Chebath J. (1997). Oncogene, 15, 569-577.
42. Schaper F, Gendo C, Eck M, Schmitz J, Grimm C, Anhuf D, Kerr IM and Heinrich PC. (1998). Biochem. J., 335, 557-565.
43. Sherr CJ and Roberts JM. (1995). Genes. Dev., 9, 1149-1163.
44. Sporeno E, Barbato G, Graziani R, Pucci P, Nitti G and Paonessa G. (1994). Cytokine, 6, 255-264.
45. Stahl N, Farruggella TJ, Boulton TG, Zhong Z, Darnell Jr JE and Yancopoulos GD. (1995). Science, 267, 1349-1353.
46. Swope VB, Abdel-Maleck Z, Kassem LM and Nordlund JJ. (1991). J. Invest. Dermatol., 96, 180-185.
47. Symes A, Stahl N, Reeves SA, Farruggella T, Servidei T, Gearan T, Yancopoulos G and Fink JS. (1997). Curr. Biol., 7, 697-700.
48. Taga T, Hibi M, Hirata Y, Yamasaki K, Yasukawa K, Matsuda T, Hirano T and Kishimoto T. (1989). Cell, 58, 573-581.
49. Takizawa H, Ohtoshi T, Ohta K, Yamashita N, Hirohata S, Hirai K, Hiramatsu K and Ito K. (1993). Cancer Res., 53, 4175-4181.
50. Thiel S, Behrmann I, Dittrich E, Muys L, Tavernier J, Wijdenes J, Heinrich PC and Graeve L. (1998). Biochem. J., 330, 47-54.
51. Wegenka UM, Buschmann J, Lütticken C, Heinrich PC and Horn F. (1993). Mol. Cell. Biol., 13, 276-288.
52. Weiergräber O, Hemmann U, Küster A, Müller-Newen G, Schneider J, Rose-John S, Kurschat P, Brakenhoff JP, Hart MH, Stabel S and Heinrich PC. (1995). Eur. J. Biochem., 234, 661-669
53. Wong LH, Krauer KG, Hatzinisiriou I, Estcourt MJ, Hersey P, Tam ND, Edmondson S, Devenish RJ and Ralph SJ. (1997). J. Biol. Chem., 272, 28779-28785.
54. Yamanaka Y, Nakajima K, Fukada T, Hibi M and Hirano T. (1996). EMBO J., 15, 1557-1565.
55. Zarling JM, Shoyab M, Marquardt H, Hanson MB, Lioubin MN and Todaro GJ. (1986). Proc. Natl. Acad. Sci. USA, 83, 9739-9743.
56. Zhong Z, Wen Z and Darnell Jr JE. (1994) Science. 264, 95-98.