Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation

EMBO Journal

Volumn 16, Issue 2, 1997, Pages 306-317

  Durand, Béatrice ^a   Gao, Fen Biao ^a   Raff, Martin ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cdk inhibitor; Cell cycle; Kip1; Oligodendrocytes; p27

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN D1; CYCLIN DEPENDENT KINASE; MYELIN; TRANSFERASE INHIBITOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; MITOSIS INHIBITION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN DEFICIENCY; RAT; STEM CELL; VERTEBRATE;

ANIMALS; CDC2 PROTEIN KINASE; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; CYCLINS; ENZYME INHIBITORS; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MICROTUBULE-ASSOCIATED PROTEINS; OLIGODENDROGLIA; ONCOGENE PROTEINS; PLATELET-DERIVED GROWTH FACTOR; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA; VERTEBRATA;

EID: 0031026190     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.2.306     Document Type: Article

References (81)

1. Aprelikova, O., Xiong, Y. and Liu, E. (1995) Both p16 and p21 families of cyclin dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase. J. Biol. Chem., 230, 18195-18197.
2. Barres, B. and Raff, M. (1994) Control of oligodendrocyte number in the developing rat optic nerve. Neuron, 12, 935-942.
3. Barres, B., Hart, I., Coles, H., Burne, J., Voyvodic, J., Richardson, W. and Raff, M. (1992) Cell death and control of cell survival in the oligodendrocyte lineage. Cell, 70, 31-46.
4. Barres, B., Schmid, R., Sendtner, M. and Raff, M. (1993) Multiple extracellular signals are required for long term oligodendrocyte survival. Development, 118, 283-295.
5. Barres, B., Lazar, M. and Raff, M. (1994) A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development. Development, 120, 1097-1108.
6. Böller, O. and Noble, M. (1994) Measurement of time in oligodendrocyte-Type 2 astrocyte (O-2A) progenitors is a cellular process distinct from differentiation or division. Dev. Biol., 162, 525-538.
7. Bottenstein, J. and Sato, G. (1979) Growth of a rat neuroblastoma cell line in serum-free supplemented medium. Proc. Natl Acad. Sci. USA, 76, 514-517.
8. cdc2 kinases in PC12 pheochromocytoma cells. Mol. Biol. Cell, 5, 1225-1241.
9. Burger, C., Wick, M. and Muller, R. (1994) Lineage specific regulation of cell cycle gene expression in differentiating myeloid cells. J. Cell Sci., 107, 2047-2054.
10. Dulic, V., Drullinger, L., Lees, E., Reed, S. and Stein, G. (1993) Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes. Proc. Natl Acad. Sci. USA, 90, 11034-11038.
11. Eisenbarth, G., Walsh, F. and Nirenburg, M. (1979) Monoclonal antibodies to a plasma membrane antigen of neurons. Proc. Natl Acad. Sci. USA, 76, 4913-4916.
12. Fero, M. et al. (1996) A syndrome of multi-organ hyperplasia with features of gigantism, tumorigenesis and female sterility in p27Kip1-deficient mice. Cell, 85, 733-744.
13. ffrench Constant, C. and Raff, M.C. (1986) The oligodendrocyte-type-2 astrocyte cell lineage is specialized for myelination. Nature, 323, 335-338.
14. Fulton, B.P., Burne, J.F. and Raff, M.C. (1992) Visualization of O-2A progenitor cells in developing and adult rat optic nerve by quisqualate-stimulated cobalt uptake. J. Neurosci., 12, 4816-4833.
15. Gotz, R., Kolbeck, R., Lottspeich, F. and Barde, Y. (1992) Production and characterisation of recombinant mouse neurotrophin-3. Eur. J. Biochem., 204, 745-749.
16. Halevy, O., Novitch, B., Spicer, D., Skapek, S., Rhee, J., Hannon, G., Beach, D. and Lassar, A. (1995) Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science, 267, 1018-1021.
17. Hara, E., Smith, R., Parry, D., Tahara, H., Stone, S. and Peters, G. (1996) Regulation of p16Cdkn2 expression and its implication for cell immortalisation and senescence. Mol. Cell. Biol., 16, 859-867.
18. Harper, J. et al. (1995) Inhibition of cyclin-dependent kinases by p21. Mol. Biol. Cell, 6, 387-400.
19. Hart, I., Richardson, W., Bolsover, S. and Raff, M. (1989a) PDGF and intracellular signalling in the timing of oligodendrocyte differentiation. J. Cell Biol., 109, 3411-3417.
20. Hart, I., Richardson, W., Heldin, C.-H., Westermark, B. and Raff, M. (1989b) PDGF receptors on cells of the oligodendrocyte-type-2 astrocyte (O-2A) cell lineage. Development, 105, 595-603.
21. Hart, I., Richardson, W. and Raff, M. (1992) PDGF increases the expression of fos and jun in newly formed oligodendrocytes that have become resistant to the mitogenic effect of PDGF. Glia, 6, 310-313.
22. Hayes, T., Valtz, N. and McKay, R. (1991) Downregulation of Cdc2 upon terminal differentiation of neurons. New Biol., 3, 259-269.
23. Hengst, L. and Reed, S. (1996) Translational control of p27Kip1 accumulation during the cell cycle. Science, 271, 1861-1864.
24. Horiguchi-Yamada, J., Yamada, H., Nakada, S., Ochi, K. and Nemoto, T. (1994) Changes of G1 cyclins, cdk2, and cyclin A during the differentiation of HL60 cells induced by TPA. Mol. Cell. Biochem., 132, 31-37. Hunter, T. and Pines, J. (1994) Cyclins and cancer II: cyclin D and CDK inhibitors come of age. Cell, 79, 573-582.
25. Horiguchi-Yamada, J., Yamada, H., Nakada, S., Ochi, K. and Nemoto, T. (1994) Changes of G1 cyclins, cdk2, and cyclin A during the differentiation of HL60 cells induced by TPA. Mol. Cell. Biochem., 132, 31-37. Hunter, T. and Pines, J. (1994) Cyclins and cancer II: cyclin D and CDK inhibitors come of age. Cell, 79, 573-582.
26. Itoh, N., Mima, T. and Mikawa, T. (1996) Loss of fibroblast growth factor receptors is necessary for terminal differentiation of embryonic limb muscle. Development, 122, 291-300.
27. Jahn, L., Sadoshima, J. and Izumo, S. (1994) Cyclins and cyclin-dependent kinases are differentially regulated during terminal differentiation of C2C12 muscle cells. Exp. Cell Res., 212, 297-307.
28. Jiang, H., Lin, J., Su, Z., Collart, F., Huberman, E. and Fisher, P. (1994) Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, Waf1/Cip1, expression in the absence of p53, Oncogene, 9, 3397-3406.
29. Kip1) of cyclin-dependent kinase 4 activation. Cell, 79, 487-496.
30. King, R., Jackson, P. and Kirschner, M. (1994) Mitosis in transition. Cell, 79, 563-572.
31. Kiyokawa, H. et al. (1996) Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27Kip1. Cell, 85, 721-732.
32. Larsson, O., Zetterberg, A. and Engstrom, W. (1985) Cell-cycle-specific induction of quiescence achieved by limited inhibition of protein synthesis: counteractive effect of addition of purified growth factors. J. Cell Sci., 75, 259-268.
33. Lee, M.-H., Reynisdottir, I. and Massagué, J. (1995) Cloning of p57Kip2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev., 9, 639-649.
34. Lee, M., Nikolic, M., Baptista, C., Lai, E., Tsai, L. and Massagué, J. (1996) The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons. Proc. Natl Acad. Sci. USA, 93, 3259-3263.
35. Lees, E. (1995) Cyclin dependent kinase regulation. Curr. Opin. Cell Biol., 7, 773-780.
36. Lillien, L. and Raff, M. (1990) Differentiation signals in the CNS: type-2 astrocyte development in vitro as a model system. Neuron, 5, 111-119.
37. Lucibello, F., Sewing, A., Brusselbach, S., Burger, C. and Muller, R. (1993) Deregulation of cyclins D1 and E and suppression of cdk2 and cdk4 in senescent human fibroblasts. J. Cell Sci., 105, 123-133.
38. Macleod, K., Sherry, N., Hannon, G., Beach, D., Tokino, T., Kinzler, K., Vogelstein, B. and Jacks, T. (1995) p-53 independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev., 9, 935-944.
39. Magaud, J., Sargent, I. and Mason, D. (1988) Detection of human white cell proliferative responses by immunoenzymatic measurement of bromodeoxyuridine uptake. J. Immunol. Methods, 106, 95-100.
40. Cip1 inhibitor family, is a candidate tumor suppressor gene. Genes Dev., 9, 650-662.
41. Morgan, D. (1995) Principles of CDK regulation. Nature, 374, 131-134.
42. Nakayama, K., Ishida, N., Shirane, M., Inomata, A., Inoue, T., Shishido, N., Horii, I., Loy, D. and Nakayama, K.-I. (1996) Mice lacking p27Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia and pituitary tumors. Cell, 85, 707-720.
43. Nebreda, A., Gannon, J. and Hunt, T. (1995) Newly synthesised protein(s) must associate with p34cdc2 to activate MAP kinase and MPF during progesterone-induced maturation of Xenopus oocytes. EMBO J., 14, 5597-5607.
44. Noble, M. and Murray, K. (1984) Purified astrocytes promote the in vitro division of a bipotential glial progenitor cell. EMBO J., 3, 2243-2247.
45. Noda, A., Nina, Y., Venable, S., Pereira-Smith, O. and Smith, J. (1994) Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res., 211, 90-98.
46. Nourse, J., Firpo, E., Flanagan, W., Coats, S., Polyak, K., Lee, M., Massagué, J., Crabtee, G. and Roberts, J. (1994) Interleukin-2-mediated elimination of the p27Kip1 cyclin dependent kinase inhibitor prevented by rapamycin. Nature, 372, 570-573.
47. Okuda, A., Matsuzak, A. and Kimura, G. (1989) Increase in c-fos and c-myc mRNA levels in untransformed and SV40-transtormed 3Y1 fibroblasts after addition of serum: its relationship to the control of initiation of S phase. Exp. Cell Res., 185, 258-270.
48. Pagano, M., Tam, S., Theodoras, A., Beer-Romero, P. Del Sal, G., Chau, V., Renée Yew, P., Draetta, G. and Rolfe, M. (1995) Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science, 269, 682-685.
49. Parker, S., Eichele, G., Zhang, P., Rawls, A., Sands, A., Bradley, A., Olson, A., Harper, J. and Elledge, S. (1995) p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science, 267, 1024-1027.
50. Peter, M. and Herskowitch, I. (1994) Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle. Cell, 79, 181-184.
51. Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev., 8, 9-22.
52. Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell, 78, 59-66.
53. Raff, M. (1989) Glial cell diversification in the rat optic nerve. Science, 243, 1450-1455.
54. Raff, M., Williams, B. and Miller, R. (1984) The in vitro differentiation of a bipotential glial progenitor cell. EMBO J., 3, 1857-1864.
55. Raff, M., Abney, E. and Fok-Seang, J. (1985) Reconstitution of a developmental clock in vitro: a critical role for astrocytes in the timing of oligodendrocyte differentiation. Cell, 42, 61-69.
56. Raff, M., Lillien, L., Richardson, W., Burnem, J. and Noble, M. (1988) Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture. Nature, 333, 562-565.
57. Ranscht, B., Clapshaw, P., Price, J., Noble, M. and Seifert, W. (1982) Development of oligodendrocytes and Schwann cells studied with a monoclonal antibody against galactocerebroside. Proc. Natl Acad. Sci. USA, 79, 2709-2713.
58. Reed, S., Bailly, E., Dulic, V., Hengst, L., Resnitzky, D. and Slingerland, J. (1994) G1 control in mammalian cells. J. Cell Sci. Suppl., 18, 69-73.
59. Reynisdóttir, I., Polyak, K., Iavarone, A. and Massagué, J. (1995) Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev., 9, 1831-1845.
60. Richardson, W., Raff, M. and Noble, M. (1990) The oligodendrocyte-type-2 astrocyte lineage. Semin. Neurosci., 2, 445-454.
61. Saatcioglu, F., Claret, F. and Karin, M. (1994) Negative transcriptional regulation by nuclear receptors. Semin. Cancer Biol., 5, 347-359.
62. Serrano, M., Lee, H.-W., Cordon-Cardo, C., Beach, D. and Delinho, R. (1996) Role of the INK4a locus in tumor suppression and cell mortality. Cell, 85, 27-37.
63. Sherr, C. (1994) G1 phase progression: cycling on cue. Cell, 79, 551-556.
64. Sherr, C. (1995) D-type cyclins. Trends Biochem. Sci., 20, 187-190.
65. Sherr, C. and Roberts, J. (1995) Inhibitors of mammalian G1 cyclin dependent kinases. Genes Dev., 9, 1149-1163.
66. Skapek, S., Rhee, J., Spicer, D. and Lassar, A. (1995) Inhibition of myogenic differentiation in proliferating myoblasts by cyclin-D1-dependent kinase. Science, 267, 1022-1024.
67. Small, R., Riddle, P. and Noble, M. (1987) Evidence for migration of oligodendrocyte-type-2 astrocyte progenitor cells into the developing rat optic nerve. Nature, 328, 155-157.
68. Soos, T. et al. (1996) Formation of p27-CDK complexes during the human mitotic cell cycle. Cell Growth Differ., 7, 135-146.
69. Stein, G. and Dulic, V. (1995) Origins of G1 arrest in senescent human fibroblasts. BioEssays, 17, 537-543.
70. Steinman, R., Hoffman, B., Iro, A., Guillouf, C., Liebermann, D. and El-Houseini, M. (1994) Induction of p21 (Waf-1/Cip1) during differentiation. Oncogene, 9, 3389-3396.
71. Stockli, K., Lottspeich, F., Sendnter, M., Masiakowski, P., Carrol, P., Gotz, R., Lindholm, D. and Thoenen, H. (1989) Molecular cloning expression and regional distribution of rat ciliary neurotrophic factor. Nature, 342, 920-923.
72. Tamaru, T., Okada, M. and Nakagawa, H. (1994) Differential expression of D type cyclins during neuronal maturation. Neurosci. Lett., 168, 229-232.
73. Temple, S. and Raff, M. (1985) Differentiation of a bipotential glial progenitor cell in single cell microculture. Nature, 313, 223-225.
74. Temple, S. and Raff, M. (1986) Clonal analysis of oligodendrocyte development in culture: evidence for a developmental clock that counts cell divisions. Cell, 44, 773-779.
75. Toyoshima, H. and Hunter, T. (1994) p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21. Cell, 78, 67-74.
76. Waters, C., Littlewood, T. Hancock, D., Moore, J. and Evan, G. (1991) c-myc protein expression in untransformed fibroblasts. Oncogene, 6, 797-805.
77. Wolswijk, G. and Noble, M. (1989) Identification of an adult-specific glial progenitor cell. Development, 105, 387-400.
78. Yaffe, D. and Saxel, O. (1977) Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle. Nature, 270, 725-727.
79. Yan, G.-Z. and Ziff, E. (1995) NGF regulates the PC12 cell cycle machinery through specific inhibition of the cdk kinases and induction of cyclin D1. J. Neurosci., 15, 6200-6212.
80. Zetterberg, A. and Larsson, O. (1991) Coordination between cell growth and cell cycle transit in animal cells. Cold Spring Harbor Symp. Quant. Biol., 56, 137-147.
81. Zetterberg, A., Larsson, O. and Wiman, K. (1995) What is the restriction point. Curr. Opin. Cell Biol., 7, 835-842.