Aberrant p27(kip1) expression in endocrine and other tumors

American Journal of Pathology

Volumn 150, Issue 2, 1997, Pages 401-407

  Lloyd, Ricardo V ^a   Jin, Long ^a   Qian, Xiang ^a   Kulig, Elzbieta ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; KI 67 ANTIGEN; MONOCLONAL ANTIBODY KI 67; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; ENZYME INHIBITOR; MICROTUBULE ASSOCIATED PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CELL CYCLE; CONTROLLED STUDY; ENDOCRINE TUMOR; HELA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOPHYSIS TUMOR; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LABELING INDEX; MAJOR CLINICAL STUDY; PARATHYROID ADENOMA; PARATHYROID HYPERPLASIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH; ENDOCRINE GLAND; HYPERPLASIA; METABOLISM; NEOPLASM; REFERENCE VALUE; TISSUE DISTRIBUTION;

CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; ENDOCRINE GLAND NEOPLASMS; ENDOCRINE GLANDS; ENZYME INHIBITORS; HUMANS; HYPERPLASIA; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASMS; REFERENCE VALUES; TISSUE DISTRIBUTION; TUMOR SUPPRESSOR PROTEINS;

EID: 0030614492     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Sherr CJ: G1 phase progression: cycling on cue. Cell 1994. 79:551-555
2. Hunter T, Pines J: Cyclins and cancer, II. Cyclin D and CDK inhibitors come of age. Cell 1994, 79:573-582
3. Sherr CJ, Roberts JM: Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 1995, 9:1149-1163
4. Kamb A: Cell-cycle regulators and cancer. Trends Genet 1995, 11:136-140
5. Guan KL, Jenkins CW, Li Y, Nichols MA, Wu X, O'Keefe CL, Matera AG, Xiong Y: Growth suppression by p 18, a P16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. Genes Dev 1994, 8:2939-2952
6. Mirai H, Roussel MF, Kato JY, Ashmun RA, Sherr CJ: Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6, Mol Cell Biol 1995, 15:2672-2681
7. Hirama T, Koeffler HP: Role of the cyclin-dependent kinase inhibitors in the development of cancer, Blood 1995. 86:841-854
8. Jin X, Nguyen D, Zhang WW, Kyritsis AP, Roth JA: Cell cycle arrest and inhibition of tumor cell proliferation by the p16/lNK4 gene mediated by an adenovirus vector. Cancer Res 1995, 55:3250-3253
9. Reed JA, Loganzo F Jr, Shea CR, Walker GJ, Flores JF, Glendening JM, Bogdany JK, Shiel MJ, Haluska FG, Fountain JW: Loss of expression of the p16/cyclindependent kinase inhibitor 2 tumor suppressor gene in melanocytic lesions correlates with invasive stage of tumor progression, Cancer Res 1995, 55:2713-2718
10. Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D: p21 is a universal inhibitor of cyclin kinases. Nature 1993, 366:701-704
11. EI-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B: WAF1, a potential mediator of p53 tumor suppression. Cell 1993:75:817-825
12. PolyakK, KatoJY, Solomon MJ, SherrCJ, Massague J, Roberts JM, Koff A: p27 kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev 1994, 8:9-22
13. Polyak K, Lee MH, Erdjument-Bromage H, Koff A, Roberts JM, Tempst P, Massague J: Cloning of p27kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals, Cell 1994, 78:59-66
14. 1 cyclin-Cdk protein kinase activity is related to p21. Cell 1994, 78:67-74
15. Matsuoka S, Edwards MC, Bai C, Parker S, Zhang P, Baldini A, Harper JW, Elledge SJ: p57/Kip2, a structurally distinct member of the p21/CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene. Genes Dev 1995, 15:650-662
16. Lee MH, Reynisdottir L, Massague J: Cloning of p57/ Kip2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution, Genes Dev 1995, 9:639-649
17. kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors, Cell 1996, 85:707-720
18. Kiyokawa H, Kinerman RD, Manova-Todorova M, Scares VC, Huffman ES, Ono M, Khanam D, Hayday AC, Frohman LA, Koff A: Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27 kip1. Cell 1996, 85:721-732
19. klp1-deficient mice. Cell 1996, 85:733-744
20. Lloyd RV, Shmidt K, Coleman K, Wilson BS: Prolactin and growth hormone synthesis and thymidine incorporation in dissociated rat pituitary tumor cells, Proc Soc Exp Biol Med 1986, 181:18-23
21. Qian X, Jin L, Grande JP, Lloyd RV: Transforming growth factor-βand p27 expression in pituitary cells, Endocrinology 1996, 137:3051-3060
22. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature 1970, 227:680-685
23. klp1 gene to 12p13 and its analysis in leukemias, Cancer Res 1995, 55:1206-1210
24. klp1 chromosomal mapping to 12p 12-12p13 and absence of mutations in human tumors. Cancer Res 1995, 55: 1211-1214
25. kip1 in human malignancies. Cancer Res 1995, 35:2266- 2269
26. klp1. J Clin Invest 1996, 97:1983-1988
27. kip1 mutation found in breast cancer. Cancer Res 1996, 56:2400-2404
28. 27kip1 in C3H 10 T1/2 mouse fibroblasts, Cancer Res 1995, 55:1413-1416
29. Poon RYC, Toyoshima H, Hunter T: Redistribution of the CDK inhibitor p27 between different cyclin CDK complexes in the mouse fibroblast cell cycle and in cells arrested with levostatin or ultraviolet irradiation, Mol Biol Cell 1995, 6:1197-1213
30. Gerdes J, Lemke IT, Baisch H, Wacker HH, Schwab V, Stein H: Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki67. J Immunol 1983, 133:1710-1715
31. Schonk DM, Kuijpers HJH, van Drunen E: Assignment of the gene(s) involved in the expression of the proliferation-related ki67 antigen to human chromosome 10. Hum Genet 1989, 83:297-299
32. Verheijen R, Kuijpers HJH, van Driel R, Beck JL, van Dierendonck JH, Brakenhoff GJ, Ramaeckers FC: Ki67 detects a nuclear matrix-associated proliferation-related antigen. II, Localization in mitotic cells and association with chromosomes, J Cell Sci 1989, 92:531-546
33. Broun DC, Gatter KC: Monoclonal antibody Ki67: its use in histopathology. Histopathology 1990, 17:409-503
34. Gerdes J, Becker MH, Key G, Caltoretti G: Immunohistochemical detection of tumor growth fraction (Ki67 antigen) in formalin-fixed and routinely processed tissues, J Pathol 1992, 168:85
35. INk4a gene product in human pituitary tumors. Cancer Res 1996, 56:2493-2496
36. INK4a expression in human breast cancer. Am J Pathol 1996, 149:15-20
37. kip1 accumulation during the cell cycle. Science 1996, 271: 1861-1864
38. kip1 for restriction point control of the fibroblast cell cycle. Science 1996, 272:877-880
39. kip1 in neurons. Proc Natl Acad Sci USA 1996, 93:3259-3263