Tumor suppression and inhibition of aneuploid cell accumulation in human brain tumor cells by ectopic overexpression of the cyclin-dependent kinase inhibitor p27KIP1

Journal of Clinical Investigation

Volumn 97, Issue 8, 1996, Pages 1983-1988

  Chen, Jun ^a   Willingham, Timothy ^a   Shuford, Matthew ^a   Nisen, Perry D ^a,b  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Adenovirus; Aneuploidy; Brain tumors; Cell cycle; Gene therapy

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLINE;

ANEUPLOIDY; ARTICLE; BRAIN TUMOR; CANCER INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE;

ANEUPLOIDY; ANIMALS; ASTROCYTOMA; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; CELL LINE; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; DNA, NEOPLASM; ENZYME INHIBITORS; GENE EXPRESSION; HUMANS; MICE; MICE, NUDE; MICROTUBULE-ASSOCIATED PROTEINS; PROTAMINE KINASE; RECOMBINANT PROTEINS; THYMIDINE; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0029988453     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118631     Document Type: Article

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