메뉴 건너뛰기




Volumn 59, Issue 15, 1999, Pages 3705-3711

The cell cycle regulator p27(kip1) contributes to growth and differentiation of osteoblasts

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; PROTEIN P21; PROTEIN P27;

EID: 17444430336     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (96)

References (57)
  • 1
    • 0027938209 scopus 로고
    • Cyclins and cancer II: Cyclin D and cdk inhibitors come of age
    • Hunter, T., and Pines, J. Cyclins and cancer II: cyclin D and cdk inhibitors come of age. Cell, 79: 573-582, 1994.
    • (1994) Cell , vol.79 , pp. 573-582
    • Hunter, T.1    Pines, J.2
  • 2
    • 0028171292 scopus 로고
    • 1 phase progression: Cycling on cue
    • 1 phase progression: cycling on cue. Cell, 79: 551-555, 1994.
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.J.1
  • 3
    • 0030657690 scopus 로고    scopus 로고
    • The restriction point and control of cell proliferation
    • Planas-Silva, M. D., and Weinberg, R. A. The restriction point and control of cell proliferation. Curr. Opin. Cell Biol., 9: 768-772, 1997.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 768-772
    • Planas-Silva, M.D.1    Weinberg, R.A.2
  • 4
    • 0026703325 scopus 로고
    • Creative blocks: Cell-cycle checkpoints and feedback controls
    • Murray, A. W. Creative blocks: cell-cycle checkpoints and feedback controls. Nature (Lond.), 359: 599-604, 1992.
    • (1992) Nature (Lond.) , vol.359 , pp. 599-604
    • Murray, A.W.1
  • 6
    • 0027731971 scopus 로고
    • Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
    • Gu, Y., Turck, C. W., and Morgan, D. O. Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature (Lond.), 366: 707-710, 1993.
    • (1993) Nature (Lond.) , vol.366 , pp. 707-710
    • Gu, Y.1    Turck, C.W.2    Morgan, D.O.3
  • 10
    • 0028179669 scopus 로고
    • p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest
    • Polyak, K., Kato, J. Y., Solomon, M. J., Sherr, C. J., Massague, J., Roberts, J. M., and Koff, A. p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev., 8: 9-22, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 9-22
    • Polyak, K.1    Kato, J.Y.2    Solomon, M.J.3    Sherr, C.J.4    Massague, J.5    Roberts, J.M.6    Koff, A.7
  • 11
    • 0028363519 scopus 로고
    • 1 cyclin-Cdk protein kinase activity, is related to p21
    • 1 cyclin-Cdk protein kinase activity, is related to p21. Cell, 78: 67-74, 1994.
    • (1994) Cell , vol.78 , pp. 67-74
    • Toyoshima, H.1    Hunter, T.2
  • 12
    • 0028988158 scopus 로고
    • Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
    • Lee, M. H., Reynisdottir, I., and Massague, J. Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev., 9: 639-649, 1995.
    • (1995) Genes Dev. , vol.9 , pp. 639-649
    • Lee, M.H.1    Reynisdottir, I.2    Massague, J.3
  • 13
    • 0028988159 scopus 로고
    • p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene
    • Matsuoka, S., Edwards, M. C., Bai, C., Parker, S., Zhang, P., Baldini, A., Harper, J. W., and Elledge, S. J. p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene. Genes Dev., 9: 650-662, 1995.
    • (1995) Genes Dev. , vol.9 , pp. 650-662
    • Matsuoka, S.1    Edwards, M.C.2    Bai, C.3    Parker, S.4    Zhang, P.5    Baldini, A.6    Harper, J.W.7    Elledge, S.J.8
  • 14
    • 0028582034 scopus 로고
    • Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/ MTS2-related CDK6 inhibitor, correlates with wild-type pRb function
    • Guan, K. L., Jenkins, C. W., Li, Y., Nichols, M. A., Wu, X., O'Keefe, C. L., Matera, A. G., and Xiong, Y. Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/ MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. Genes Dev., 8: 2939-2952, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 2939-2952
    • Guan, K.L.1    Jenkins, C.W.2    Li, Y.3    Nichols, M.A.4    Wu, X.5    O'Keefe, C.L.6    Matera, A.G.7    Xiong, Y.8
  • 15
    • 0028911830 scopus 로고
    • Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4
    • Chan, F. K., Zhang, J., Cheng, L., Shapiro, D. N., and Winoto, A. Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4. Mol. Cell. Biol., 15: 2682-2688, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2682-2688
    • Chan, F.K.1    Zhang, J.2    Cheng, L.3    Shapiro, D.N.4    Winoto, A.5
  • 16
    • 0028168242 scopus 로고
    • p15INK4B is a potential effector of TGF-β-induced cell cycle arrest
    • Hannon, G. J., and Beach, D. p15INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature (Lond.), 371: 257-261, 1994.
    • (1994) Nature (Lond.) , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 17
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano, M., Hannon, G. J., and Beach, D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature (Lond.), 366: 704-707, 1993.
    • (1993) Nature (Lond.) , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 19
    • 0028863849 scopus 로고
    • Regulation of cyclin e and p27kip during mitosis in BALB/c 3T3 cells
    • Agrawal, D., Dong, F., Wang, Y. Z., Kayda, D., and Pledger, W. J. Regulation of cyclin E and p27kip during mitosis in BALB/c 3T3 cells. Cell Growth Differ., 6: 1199-1205, 1995.
    • (1995) Cell Growth Differ. , vol.6 , pp. 1199-1205
    • Agrawal, D.1    Dong, F.2    Wang, Y.Z.3    Kayda, D.4    Pledger, W.J.5
  • 21
    • 0028941483 scopus 로고
    • Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD
    • Washington DC
    • Halevy, O., Novitch, B. G., Spicer, D. B., Skapek, S. X., Rhee, J., Hannon, G. J., Beach, D., and Lassar, A. B. Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science (Washington DC), 267: 1018-1021, 1995.
    • (1995) Science , vol.267 , pp. 1018-1021
    • Halevy, O.1    Novitch, B.G.2    Spicer, D.B.3    Skapek, S.X.4    Rhee, J.5    Hannon, G.J.6    Beach, D.7    Lassar, A.B.8
  • 22
  • 23
    • 0029664461 scopus 로고    scopus 로고
    • Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle
    • Washington DC
    • Coats, S., Flanagan, W. M., Nourse, J., and Roberts, J. M. Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle. Science (Washington DC), 272: 877-880, 1996.
    • (1996) Science , vol.272 , pp. 877-880
    • Coats, S.1    Flanagan, W.M.2    Nourse, J.3    Roberts, J.M.4
  • 25
    • 0030010591 scopus 로고    scopus 로고
    • Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
    • Nakayama, K., Ishida, N., Shirane, M., Inomata, A., Inoue, T., Shishido, N., Horii, I., and Loh, D. Y. Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell, 85: 707-720, 1996.
    • (1996) Cell , vol.85 , pp. 707-720
    • Nakayama, K.1    Ishida, N.2    Shirane, M.3    Inomata, A.4    Inoue, T.5    Shishido, N.6    Horii, I.7    Loh, D.Y.8
  • 29
    • 0002303623 scopus 로고    scopus 로고
    • Mechanisms regulating osteoblast proliferation and differentiation
    • J. P. Bilezikian, L. G. Raisz, and G. A. Rodan (eds.), San Diego: Academic Press
    • Stein, G. S., Lian, J. B., Stein, J. S., van Wijnen, A. J., Frenkel, B., and Montecino, M. Mechanisms regulating osteoblast proliferation and differentiation. In: J. P. Bilezikian, L. G. Raisz, and G. A. Rodan (eds.), Principles of Bone Biology, pp. 69-86, San Diego: Academic Press, 1996.
    • (1996) Principles of Bone Biology , pp. 69-86
    • Stein, G.S.1    Lian, J.B.2    Stein, J.S.3    Van Wijnen, A.J.4    Frenkel, B.5    Montecino, M.6
  • 30
    • 0028800153 scopus 로고
    • Expression of cell cycle regulatory factors in differentiating osteoblasts: Postproliferative up-regulation of cyclins B and E
    • Smith, E., Frenkel, B., Schlegel, R., Giordano, A., Lian, J. B., Stein, J. L., and Stein, G. S. Expression of cell cycle regulatory factors in differentiating osteoblasts: postproliferative up-regulation of cyclins B and E. Cancer Res., 55: 5019-5024, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 5019-5024
    • Smith, E.1    Frenkel, B.2    Schlegel, R.3    Giordano, A.4    Lian, J.B.5    Stein, J.L.6    Stein, G.S.7
  • 31
    • 0030811548 scopus 로고    scopus 로고
    • Post-proliferative cyclin E-associated kinase activity in differentiated osteoblasts: Inhibition by proliferating osteoblasts and osteosarcoma cells
    • Smith, E., Frenkel, B., MacLachlan, T. K., Giordano, A., Stein, J. L., Lian, J. B., and Stein, G. S. Post-proliferative cyclin E-associated kinase activity in differentiated osteoblasts: inhibition by proliferating osteoblasts and osteosarcoma cells. J. Cell. Biochem., 66: 141-152, 1997.
    • (1997) J. Cell. Biochem. , vol.66 , pp. 141-152
    • Smith, E.1    Frenkel, B.2    MacLachlan, T.K.3    Giordano, A.4    Stein, J.L.5    Lian, J.B.6    Stein, G.S.7
  • 32
    • 0025316785 scopus 로고
    • Progressive development of the rat osteoblast phenotype in vitro: Reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix
    • Owen, T. A., Aronow, M., Shalhoub, V., Barone, L. M., Wilming, L., Tassinari, M. S., Kennedy, M. B., Pockwinse, S., Lian, J. B., and Stein, G. S. Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix. J. Cell. Physiol., 143: 420-430, 1990.
    • (1990) J. Cell. Physiol. , vol.143 , pp. 420-430
    • Owen, T.A.1    Aronow, M.2    Shalhoub, V.3    Barone, L.M.4    Wilming, L.5    Tassinari, M.S.6    Kennedy, M.B.7    Pockwinse, S.8    Lian, J.B.9    Stein, G.S.10
  • 33
    • 0027133421 scopus 로고
    • Characterization of a 5-fluorouracil-enriched osteoprogenitor population of the murine bone marrow
    • Falla, N., van Vlasselaer, P., Bierkens, J., Borremans, B., Schoeters, G., and van Gorp, U. Characterization of a 5-fluorouracil-enriched osteoprogenitor population of the murine bone marrow. Blood, 82: 3580-3591, 1993.
    • (1993) Blood , vol.82 , pp. 3580-3591
    • Falla, N.1    Van Vlasselaer, P.2    Bierkens, J.3    Borremans, B.4    Schoeters, G.5    Van Gorp, U.6
  • 34
    • 0030992384 scopus 로고    scopus 로고
    • Activity of the osteocalcin promoter in skeletal sites of transgenic mice and during osteoblast differentiation in bone marrow-derived stromal cell cultures: Effects of age and sex
    • Frenkel, B., Capparelli, C., van Auken, M., Bryan, J., Stein, J. L., Stein, G. S., and Lian, J. B. Activity of the osteocalcin promoter in skeletal sites of transgenic mice and during osteoblast differentiation in bone marrow-derived stromal cell cultures: effects of age and sex. Endocrinology, 138: 2109-2116, 1997.
    • (1997) Endocrinology , vol.138 , pp. 2109-2116
    • Frenkel, B.1    Capparelli, C.2    Van Auken, M.3    Bryan, J.4    Stein, J.L.5    Stein, G.S.6    Lian, J.B.7
  • 35
    • 0018926608 scopus 로고
    • Parathyroid hormone-responsive clonal cell lines from rat osteosarcoma
    • Majeska, R. J., Rodan, S. B., and Rodan, G. A. Parathyroid hormone-responsive clonal cell lines from rat osteosarcoma. Endocrinology, 107: 1494-1503, 1980.
    • (1980) Endocrinology , vol.107 , pp. 1494-1503
    • Majeska, R.J.1    Rodan, S.B.2    Rodan, G.A.3
  • 36
    • 0022262165 scopus 로고
    • A simplified in situ solubilization procedure for the determination of DNA and cell number in tissue cultured mammalian cells
    • West, D. C., Sattar, A., and Kumar, S. A simplified in situ solubilization procedure for the determination of DNA and cell number in tissue cultured mammalian cells. Anal. Biochem., 147: 289-295, 1985.
    • (1985) Anal. Biochem. , vol.147 , pp. 289-295
    • West, D.C.1    Sattar, A.2    Kumar, S.3
  • 37
    • 0028170174 scopus 로고
    • TGF β alters growth and differentiation related gene expression in proliferating osteoblasts in vitro, preventing development of the mature bone phenotype
    • Breen, E. C., Ignotz, R. A., McCabe, L., Stein, J. L., Stein, G. S., and Lian, J. B. TGF β alters growth and differentiation related gene expression in proliferating osteoblasts in vitro, preventing development of the mature bone phenotype. J. Cell. Physiol., 160: 323-335, 1994.
    • (1994) J. Cell. Physiol. , vol.160 , pp. 323-335
    • Breen, E.C.1    Ignotz, R.A.2    McCabe, L.3    Stein, J.L.4    Stein, G.S.5    Lian, J.B.6
  • 39
    • 0028341364 scopus 로고
    • Effects of transforming growth factor β on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagen mRNA in long-term cultures of fetal rat calvarial osteoblasts
    • Harris, S. E., Bonewald, L. F., Harris, M. A., Sabatini, M., Dallas, S., Feng, J. Q., Ghosh-Choudhury, N., Wozney, J., and Mundy, G. R. Effects of transforming growth factor β on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagen mRNA in long-term cultures of fetal rat calvarial osteoblasts. J. Bone Miner. Res., 9: 855-863, 1994.
    • (1994) J. Bone Miner. Res. , vol.9 , pp. 855-863
    • Harris, S.E.1    Bonewald, L.F.2    Harris, M.A.3    Sabatini, M.4    Dallas, S.5    Feng, J.Q.6    Ghosh-Choudhury, N.7    Wozney, J.8    Mundy, G.R.9
  • 40
    • 0028092122 scopus 로고
    • Transforming growth factor β 1 can induce CIP1/WAF1 expression independent of the p53 pathway in ovarian cancer cells
    • Elbendary, A., Berchuck, A., Davis, P., Havrilesky, L., Bast, R. C., Jr., Iglehart, J. D., and Marks, J. R. Transforming growth factor β 1 can induce CIP1/WAF1 expression independent of the p53 pathway in ovarian cancer cells. Cell Growth Differ., 5: 1301-1307, 1994.
    • (1994) Cell Growth Differ. , vol.5 , pp. 1301-1307
    • Elbendary, A.1    Berchuck, A.2    Davis, P.3    Havrilesky, L.4    Bast Jr., R.C.5    Iglehart, J.D.6    Marks, J.R.7
  • 42
    • 0025764218 scopus 로고
    • Pleiotropic effects of vitamin D on osteoblast gene expression are related to the proliferative and differentiated state of the bone cell phenotype: Dependency upon basal levels of gene expression, duration of exposure, and bone matrix competency in normal rat osteoblast cultures
    • Owen, T. A., Aronow, M. S., Barone, L. M., Bettencourt, B., Stein, G. S., and Lian, J. B. Pleiotropic effects of vitamin D on osteoblast gene expression are related to the proliferative and differentiated state of the bone cell phenotype: dependency upon basal levels of gene expression, duration of exposure, and bone matrix competency in normal rat osteoblast cultures. Endocrinology, 128: 1496-1504, 1991.
    • (1991) Endocrinology , vol.128 , pp. 1496-1504
    • Owen, T.A.1    Aronow, M.S.2    Barone, L.M.3    Bettencourt, B.4    Stein, G.S.5    Lian, J.B.6
  • 44
    • 0029153609 scopus 로고
    • Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β
    • Reynisdottir, I., Polyak, K., Iavarone, A., and Massague, J. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β, Genes Dev., 9: 1831-1845, 1995.
    • (1995) Genes Dev. , vol.9 , pp. 1831-1845
    • Reynisdottir, I.1    Polyak, K.2    Iavarone, A.3    Massague, J.4
  • 45
    • 0024147344 scopus 로고
    • Marrow stromal stem cells
    • Owen, M. Marrow stromal stem cells. J. Cell Sci., 10: 63-76, 1988.
    • (1988) J. Cell Sci. , vol.10 , pp. 63-76
    • Owen, M.1
  • 46
    • 0030065422 scopus 로고    scopus 로고
    • Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937
    • Liu, M., Lee, M. H., Cohen, M., Bommakanti, M., and Freedman, L. P. Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. Genes Dev., 10: 142-153, 1996.
    • (1996) Genes Dev. , vol.10 , pp. 142-153
    • Liu, M.1    Lee, M.H.2    Cohen, M.3    Bommakanti, M.4    Freedman, L.P.5
  • 47
    • 0032516898 scopus 로고    scopus 로고
    • Transcriptional activation of the p21(WAF1, CIP1, SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells
    • Bellido, T., O'Brien, C. A., Roberson, P. K., and Manolagas, S. C. Transcriptional activation of the p21(WAF1, CIP1, SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells. J. Biol. Chem., 273: 21137-21144, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 21137-21144
    • Bellido, T.1    O'Brien, C.A.2    Roberson, P.K.3    Manolagas, S.C.4
  • 50
    • 0027973043 scopus 로고
    • 1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation
    • 1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation. Cell, 79: 487-496, 1994.
    • (1994) Cell , vol.79 , pp. 487-496
    • Kato, J.Y.1    Matsuoka, M.2    Polyak, K.3    Massague, J.4    Sherr, C.J.5
  • 52
    • 85047677382 scopus 로고    scopus 로고
    • Expression of p27Kip1 in osteoblast-like cells during differentiation with parathyroid hormone
    • Onishi, T., and Hruska, K. Expression of p27Kip1 in osteoblast-like cells during differentiation with parathyroid hormone. Endocrinology, 138: 1995-2004, 1997.
    • (1997) Endocrinology , vol.138 , pp. 1995-2004
    • Onishi, T.1    Hruska, K.2
  • 53
    • 0031750613 scopus 로고    scopus 로고
    • Up-regulation of p27Kip1, p21WAF1/Cip1 and p16Ink4a is associated with, but not sufficient for, induction of squamous differentiation
    • Harvat, B. L., Wang, A., Seth, P., and Jetten, A. M. Up-regulation of p27Kip1, p21WAF1/Cip1 and p16Ink4a is associated with, but not sufficient for, induction of squamous differentiation. J. Cell Sci., 111: 1185-1196, 1998.
    • (1998) J. Cell Sci. , vol.111 , pp. 1185-1196
    • Harvat, B.L.1    Wang, A.2    Seth, P.3    Jetten, A.M.4
  • 54
    • 0031032139 scopus 로고    scopus 로고
    • Changes in cyclin-dependent kinase 2 and p27kip1 accompany glial cell differentiation of central glia-4 cells
    • Tikoo, R., Casaccia-Bonnefil, P., Chao, M. V., and Koff, A. Changes in cyclin-dependent kinase 2 and p27kip1 accompany glial cell differentiation of central glia-4 cells. J. Biol. Chem., 272: 442-447, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 442-447
    • Tikoo, R.1    Casaccia-Bonnefil, P.2    Chao, M.V.3    Koff, A.4
  • 55
    • 0028942119 scopus 로고
    • The influence of type I collagen on the development and maintenance of the osteoblast phenotype in primary and passaged rat calvarial osteoblasts: Modification of expression of genes supporting cell growth, adhesion, and extracellular matrix mineralization
    • Lynch, M. P., Stein, J. L., Stein, G. S., and Lian, J. B. The influence of type I collagen on the development and maintenance of the osteoblast phenotype in primary and passaged rat calvarial osteoblasts: modification of expression of genes supporting cell growth, adhesion, and extracellular matrix mineralization. Exp. Cell Res. 216: 35-45, 1995.
    • (1995) Exp. Cell Res. , vol.216 , pp. 35-45
    • Lynch, M.P.1    Stein, J.L.2    Stein, G.S.3    Lian, J.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.